Hua-Chien Chen

2.3k total citations · 1 hit paper
14 papers, 1.8k citations indexed

About

Hua-Chien Chen is a scholar working on Molecular Biology, Cancer Research and Epidemiology. According to data from OpenAlex, Hua-Chien Chen has authored 14 papers receiving a total of 1.8k indexed citations (citations by other indexed papers that have themselves been cited), including 11 papers in Molecular Biology, 5 papers in Cancer Research and 2 papers in Epidemiology. Recurrent topics in Hua-Chien Chen's work include MicroRNA in disease regulation (5 papers), Cancer-related molecular mechanisms research (3 papers) and RNA modifications and cancer (2 papers). Hua-Chien Chen is often cited by papers focused on MicroRNA in disease regulation (5 papers), Cancer-related molecular mechanisms research (3 papers) and RNA modifications and cancer (2 papers). Hua-Chien Chen collaborates with scholars based in Taiwan, United States and Slovakia. Hua-Chien Chen's co-authors include Shu-Jen Chen, Yi Huang, Wei-Chih Tsai, Roger Shen, Sheng‐Da Hsu, Hsien‐Da Huang, Ann‐Ping Tsou, Michael Hsiao, Ming‐Ta Hsu and Jaw‐Ching Wu and has published in prestigious journals such as Journal of Biological Chemistry, Journal of Clinical Investigation and The EMBO Journal.

In The Last Decade

Hua-Chien Chen

14 papers receiving 1.8k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

MicroRNA-122 plays a critical role in liver homeostasis and hepatocarcinogenesis

2012 670 citations Wei-Chih Tsai, Sheng‐Da Hsu et al. Journal of Clinical Investigation profile →

Peers

Hua-Chien Chen

MB

CR

EPIDE

OC

ONCOL

Chunli Wu China

Chen‐Kung Chou Taiwan

Lin Lv China

Do‐Sim Park South Korea

Nicoletta Potenza Italy

Osamu Koiwai Japan

Norimasa Tamehiro Japan

Fulvia Farabegoli Italy

Johan Vande Voorde Belgium

Margarita Hadzopoulou‐Cladaras United States

Chunli Wu China

Hua-Chien Chen

907 ×0.9

MB

356 ×0.4

CR

282 ×0.9

EPIDE

171 ×1.1

OC

154 ×1.2

ONCOL

Citations per year, relative to Hua-Chien Chen Hua-Chien Chen (= 1×) peers Chunli Wu

Countries citing papers authored by Hua-Chien Chen

Since Specialization

Citations

This map shows the geographic impact of Hua-Chien Chen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Hua-Chien Chen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Hua-Chien Chen more than expected).

Fields of papers citing papers by Hua-Chien Chen

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Hua-Chien Chen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Hua-Chien Chen. The network helps show where Hua-Chien Chen may publish in the future.

Co-authorship network of co-authors of Hua-Chien Chen

This figure shows the co-authorship network connecting the top 25 collaborators of Hua-Chien Chen. A scholar is included among the top collaborators of Hua-Chien Chen based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Hua-Chien Chen. Hua-Chien Chen is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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14 of 14 papers shown

1.

Chiu, Ching‐Chi, Rou-Shayn Chen, Hua-Chien Chen, et al.. (2019). Upregulated Expression of MicroRNA-204-5p Leads to the Death of Dopaminergic Cells by Targeting DYRK1A-Mediated Apoptotic Signaling Cascade. Frontiers in Cellular Neuroscience. 13. 399–399. 42 indexed citations

2.

Lai, Yi‐Hsuan, Hsuan Liu, Wei-Fan Chiang, et al.. (2017). MiR-31-5p-ACOX1 Axis Enhances Tumorigenic Fitness in Oral Squamous Cell Carcinoma Via the Promigratory Prostaglandin E2. Theranostics. 8(2). 486–504. 89 indexed citations

3.

Chen, Shu‐Mei, Hua-Chien Chen, Shu‐Jen Chen, et al.. (2013). MicroRNA-495 inhibits proliferation of glioblastoma multiforme cells by downregulating cyclin-dependent kinase 6. World Journal of Surgical Oncology. 11(1). 87–87. 46 indexed citations

4.

Tsai, Wei-Chih, Sheng‐Da Hsu, Tsung‐Ching Lai, et al.. (2012). MicroRNA-122 plays a critical role in liver homeostasis and hepatocarcinogenesis. Journal of Clinical Investigation. 122(8). 2884–2897. 670 indexed citations breakdown →

5.

Liu, Hsuan, Shen Liang Chen, Tzu‐Hao Wang, et al.. (2012). Epigenetic silencing of myogenic gene program by Myb‐binding protein 1a suppresses myogenesis. The EMBO Journal. 31(7). 1739–1751. 20 indexed citations

6.

Chou, Yu‐Ting, Yung-Chang Lien, Yuan‐Hung Wang, et al.. (2010). EGFR Promotes Lung Tumorigenesis by Activating miR-7 through a Ras/ERK/Myc Pathway That Targets the Ets2 Transcriptional Repressor ERF. Cancer Research. 70(21). 8822–8831. 232 indexed citations

7.

Lin, Wei-Chen, Wen‐chang Lin, Jyh-Wei Shin, et al.. (2009). Identification of microRNA in the protist Trichomonas vaginalis. Genomics. 93(5). 487–493. 59 indexed citations

8.

Lee, Cheng‐Chung, Chih‐Jung Kuo, Tzu‐Ping Ko, et al.. (2009). Structural Basis of Inhibition Specificities of 3C and 3C-like Proteases by Zinc-coordinating and Peptidomimetic Compounds. Journal of Biological Chemistry. 284(12). 7646–7655. 106 indexed citations

9.

Chen, Ching-Ping, Chi-Hung Lin, Yingying Chang, et al.. (2003). Synthesis and Biological Evaluation of N-Heterocyclic Indolyl Glyoxylamides as Orally Active Anticancer Agents. Journal of Medicinal Chemistry. 46(9). 1706–1715. 146 indexed citations

10.

Chen, Hua-Chien, et al.. (2001). MST4, a new Ste20-related kinase that mediates cell growth and transformation via modulating ERK pathway. Oncogene. 20(45). 6559–6569. 87 indexed citations

11.

Parcells, Mark S., Su‐Fang Lin, Robert L. Dienglewicz, et al.. (2001). Marek's Disease Virus (MDV) Encodes an Interleukin-8 Homolog (vIL-8): Characterization of the vIL-8 Protein and a vIL-8 Deletion Mutant MDV. Journal of Virology. 75(11). 5159–5173. 132 indexed citations

12.

Lin, Wen‐chang, Hsiao‐Wei Kao, Daniel Robinson, et al.. (2000). Tyrosine kinases and gastric cancer. Oncogene. 19(49). 5680–5689. 58 indexed citations

13.

Chen, Chung‐Yi, Fang‐Rong Chang, Yi-Chen Chia, et al.. (2000). Cytotoxic Constituents of Polyalthia longifolia var. pendula. Journal of Natural Products. 63(11). 1475–1478. 80 indexed citations

14.

Chen, Hua-Chien, Hsing-Jien Kung, & Dan R. Robinson. (1998). Digital cloning: Identification of human cDNAs homologous to novel kinases through expressed sequence tag database searching. Journal of Biomedical Science. 5(2). 86–92. 13 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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