Kostas Vekrellis

6.6k total citations · 2 hit papers
58 papers, 4.8k citations indexed

About

Kostas Vekrellis is a scholar working on Neurology, Cellular and Molecular Neuroscience and Physiology. According to data from OpenAlex, Kostas Vekrellis has authored 58 papers receiving a total of 4.8k indexed citations (citations by other indexed papers that have themselves been cited), including 43 papers in Neurology, 20 papers in Cellular and Molecular Neuroscience and 17 papers in Physiology. Recurrent topics in Kostas Vekrellis's work include Parkinson's Disease Mechanisms and Treatments (42 papers), Neurological disorders and treatments (14 papers) and Nerve injury and regeneration (13 papers). Kostas Vekrellis is often cited by papers focused on Parkinson's Disease Mechanisms and Treatments (42 papers), Neurological disorders and treatments (14 papers) and Nerve injury and regeneration (13 papers). Kostas Vekrellis collaborates with scholars based in Greece, United States and United Kingdom. Kostas Vekrellis's co-authors include Leonidas Stefanis, Evangelia Emmanouilidou, Maria Xilouri, Katerina Melachroinou, Spiros D. Garbis, Theodoros I. Roumeliotis, Lukas H. Margaritis, Maria Ntzouni, Hardy J. Rideout and David S. Park and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Nature Medicine.

In The Last Decade

Kostas Vekrellis

57 papers receiving 4.7k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Cell-Produced α-Synuclein Is Secreted in a Calcium-Dependent Manner by Exosomes and Impacts Neuronal Survival

2010 912 citations Evangelia Emmanouilidou, Katerina Melachroinou et al. profile →
Wild Type α-Synuclein Is Degraded by Chaperone-mediated Autophagy and Macroautophagy in Neuronal Cells

2008 551 citations Maria Xilouri, Kostas Vekrellis et al. profile →

Peers

Kostas Vekrellis

NEURO

PHYSI

CMN

EPIDE

Clemens R. Scherzer United States

Emma Deas United Kingdom

Laura A. Volpicelli‐Daley United States

Anne Grünewald Germany

Joseph R. Mazzulli United States

Karin M. Danzer Germany

Erin H. Norris United States

Miratul M. K. Muqit United Kingdom

Manabu Funayama Japan

Simone Engelender Israel

Clemens R. Scherzer United States

Kostas Vekrellis

1.8k ×0.6

NEURO

1.8k ×1.1

1.6k ×1.0

PHYSI

1.2k ×1.0

CMN

571 ×0.6

EPIDE

Citations per year, relative to Kostas Vekrellis Kostas Vekrellis (= 1×) peers Clemens R. Scherzer

Countries citing papers authored by Kostas Vekrellis

Since Specialization

Citations

This map shows the geographic impact of Kostas Vekrellis's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Kostas Vekrellis with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Kostas Vekrellis more than expected).

Fields of papers citing papers by Kostas Vekrellis

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Kostas Vekrellis. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Kostas Vekrellis. The network helps show where Kostas Vekrellis may publish in the future.

Co-authorship network of co-authors of Kostas Vekrellis

This figure shows the co-authorship network connecting the top 25 collaborators of Kostas Vekrellis. A scholar is included among the top collaborators of Kostas Vekrellis based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Kostas Vekrellis. Kostas Vekrellis is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Semitekolou, Maria, Manousos Makridakis, Antonia Vlahou, et al.. (2024). α-Synuclein oligomers potentiate neuroinflammatory NF-κB activity and induce Cav3.2 calcium signaling in astrocytes. Translational Neurodegeneration. 13(1). 11–11. 10 indexed citations

Vekrellis, Kostas, Evangelia Emmanouilidou, Maria Xilouri, & Leonidas Stefanis. (2024). α-Synuclein in Parkinson's Disease: 12 Years Later. Cold Spring Harbor Perspectives in Medicine. 14(11). a041645–a041645. 2 indexed citations

Kanata, Ειrini, Kostas Vekrellis, Vasilios C. Constantinides, et al.. (2024). SIMOA Diagnostics on Alzheimer’s Disease and Frontotemporal Dementia. Biomedicines. 12(6). 1253–1253. 5 indexed citations

Melachroinou, Katerina, Vasilios C. Constantinides, Nishant N. Vaikath, et al.. (2023). Assessment of Aggregated and Exosome-Associated α-Synuclein in Brain Tissue and Cerebrospinal Fluid Using Specific Immunoassays. Diagnostics. 13(13). 2192–2192. 8 indexed citations

Vaikath, Nishant N., et al.. (2023). Screening for Novel Inhibitors of Amyloid Beta Aggregation and Toxicity as Potential Drugs for Alzheimer’s Disease. International Journal of Molecular Sciences. 24(14). 11326–11326. 4 indexed citations

Melachroinou, Katerina, Sotirios P. Fortis, Gina Papadopoulou, et al.. (2023). Endogenous Alpha-Synuclein is Essential for the Transfer of Pathology by Exosome-Enriched Extracellular Vesicles, Following Inoculation with Preformed Fibrils in vivo. Aging and Disease. 15(2). 869–892. 4 indexed citations

Vaikath, Nishant N., Indulekha P. Sudhakaran, Ilham Y. Abdi, et al.. (2022). Structural and Biophysical Characterization of Stable Alpha-Synuclein Oligomers. International Journal of Molecular Sciences. 23(23). 14630–14630. 11 indexed citations

Polissidis, Alexia, Georgia Nikolopoulou, Catherine Viel, et al.. (2022). A double-hit in vivo model of GBA viral microRNA-mediated downregulation and human alpha-synuclein overexpression demonstrates nigrostriatal degeneration. Neurobiology of Disease. 163. 105612–105612. 6 indexed citations

Oliveira, Luís M. A., Thomas Gasser, Robert H. Edwards, et al.. (2021). Alpha-synuclein research: defining strategic moves in the battle against Parkinson’s disease. npj Parkinson s Disease. 7(1). 65–65. 96 indexed citations

10.

Pediaditakis, Iosif, Konstantia Kodella, Dimitris V. Manatakis, et al.. (2021). Modeling alpha-synuclein pathology in a human brain-chip to assess blood-brain barrier disruption. Nature Communications. 12(1). 5907–5907. 150 indexed citations

11.

Breza, Marianthi, Evangelia Emmanouilidou, Anastasia Bougea, et al.. (2020). Elevated Serum α-Synuclein Levels in Huntington’s Disease Patients. Neuroscience. 431. 34–39. 7 indexed citations

12.

Melachroinou, Katerina, et al.. (2020). Intrastriatal Administration of Exosome-Associated Pathological Alpha-Synuclein Is Not Sufficient by Itself to Cause Pathology Transmission. Frontiers in Neuroscience. 14. 246–246. 13 indexed citations

13.

Delenclos, Marion, Jeremy D. Burgess, Agaristi Lamprokostopoulou, et al.. (2019). Cellular models of alpha‐synuclein toxicity and aggregation. Journal of Neurochemistry. 150(5). 566–576. 85 indexed citations

14.

Emmanouilidou, Evangelia, et al.. (2019). Voltage-Gated Calcium Channels and α-Synuclein: Implications in Parkinson’s Disease. Frontiers in Molecular Neuroscience. 12. 237–237. 34 indexed citations

15.

Emmanouilidou, Evangelia, et al.. (2014). In silico modeling of the effects of alpha-synuclein oligomerization on dopaminergic neuronal homeostasis. BMC Systems Biology. 8(1). 54–54. 19 indexed citations

16.

Gonçalves, S., Anna Villar‐Piqué, Patrícia Guerreiro, et al.. (2014). The small GTPase Rab11 co-localizes with -synuclein in intracellular inclusions and modulates its aggregation, secretion and toxicity. Human Molecular Genetics. 23(25). 6732–6745. 73 indexed citations

17.

Melachroinou, Katerina, Maria Xilouri, Evangelia Emmanouilidou, et al.. (2013). Deregulation of calcium homeostasis mediates secreted α–synuclein-induced neurotoxicity. Neurobiology of Aging. 34(12). 2853–2865. 61 indexed citations

18.

Moraitou, Marina, et al.. (2012). Increased dimerization of alpha-synuclein in erythrocytes in Gaucher disease and aging. Neuroscience Letters. 528(2). 205–209. 26 indexed citations

19.

Xu, Jindong, Maria Xilouri, Junichi Shioi, et al.. (2011). Extracellular progranulin protects cortical neurons from toxic insults by activating survival signaling. Neurobiology of Aging. 32(12). 2326.e5–2326.e16. 90 indexed citations

20.

Emmanouilidou, Evangelia, Leonidas Stefanis, & Kostas Vekrellis. (2008). Cell-produced α-synuclein oligomers are targeted to, and impair, the 26S proteasome. Neurobiology of Aging. 31(6). 953–968. 174 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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