Thomas Franke

20.9k citations

49 papers · 17.6k indexed · 9 hit papers · h-index 36

Molecular Biology top 0.2%
- PI3K/AKT/mTOR signaling in cancer 21
- Protein Kinase Regulation and GTPase Signaling 6
- Cell death mechanisms and regulation 6
- Genomics, phytochemicals, and oxidative stress 5
- Cancer-related gene regulation 4
Developmental Neuroscience top 1%
Cancer Research top 0.5%
Cellular and Molecular Neuroscience top 0.5%
- Neuroscience and Neuropharmacology Research 5
Immunology top 1%
Oncology
- Cytokine Signaling Pathways and Interactions 5
Hematology
- Multiple Myeloma Research and Treatments 3

Co-authors: David R. Kaplan Lewis C. Cantley John C. Reed Michael H. Cardone Natalie Roy Eric J. Stanbridge Guy S. Salvesen Henning R. Stennicke
Cited by: Molecular Biology Developmental Neuroscience Cancer Research
Partner nations: United States Canada France

In The Last Decade

Thomas Franke

47 papers receiving 17.4k citations

Hit Papers

9 papers align trajectories log scale

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

2003 PI3K/Akt and apoptosis: size matters
2001 Akt Phosphorylates and Negatively Regulates Apoptosis Signal-Regulating Kinase 1
2001 Akt Activation Preserves Cardiac Function and Prevents Injury After Transient Cardiac Ischemia In Vivo
1999 Ca ²⁺ -Induced Apoptosis Through Calcineurin Dephosphorylation of BAD
1999 Regulation of endothelium-derived nitric oxide production by the protein kinase Akt
1998 Regulation of Cell Death Protease Caspase-9 by Phosphorylation
1997 Regulation of Neuronal Survival by the Serine-Threonine Protein Kinase Akt
1997 PI3K: Downstream AKTion Blocks Apoptosis
1995 The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

Peers

Countries citing papers authored by Thomas Franke

Since Specialization

Citations

This map shows the geographic impact of Thomas Franke's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Thomas Franke with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Thomas Franke more than expected).

Fields of papers citing papers by Thomas Franke

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Thomas Franke. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Thomas Franke. The network helps show where Thomas Franke may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Thomas Franke, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Thomas Franke Line = papers co-authored together Thomas Franke links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Context-dependent expression of a conditionally-inducible form of active Akt Soyeon Park,Robert E. Burke,Tatyana Kareva,Nikolai Kholodilov,Pascaline Aimé,Thomas Franke,Oren Levy,Lloyd A. Greene	2018	5
2	Tau pathology induces loss of GABAergic interneurons leading to altered synaptic plasticity and behavioral impairments Josien Levenga,Pavan Krishnamurthy,Hameetha B. Rajamohamedsait,Helen Wong,Thomas Franke,Peter Cain,Einar M. Sigurdsson,Charles A. Hoeffer	2013	99
3	Opposite effects of fear conditioning and extinction on dendritic spine remodelling Cora Sau Wan Lai,Thomas Franke,Wen‐Biao Gan	2012	316
4	Inhibition of 5‐HT_1A receptor‐dependent cell survival by cAMP/protein kinase A: Role of protein phosphatase 2A and Bax Shu‐chi Hsiung,Adrianne Tin,Hadassah Tamir,Thomas Franke,Kuo‐peing Liu	2008	20
5	Roles of extracellular signal‐regulated kinase and Akt signaling in coordinating nuclear transcription factor‐κB‐dependent cell survival after serotonin 1A receptor activation Shu‐chi Hsiung,Hadassah Tamir,Thomas Franke,Kuo‐peing Liu	2005	42
6	Identifying the concepts contained in outcome measures of clinical trials on musculoskeletal disorders and chronic widespread pain using the international classification of functioning, disability and health as a reference Thomas Brockow,Heide Kuhlow,Tanja Sigl,Thomas Franke,Michael Harder,Gerold Stucki,Alarcos Cieza	2004	97
7	Identifying the concepts contained in outcome measures of clinical trials on depressive disorders using the international classification of functioning, disability and health as a reference Thomas Brockow,Kathrin Wohlfahrt,Andreas Hillert,Szilvia Geyh,Martin Weigl,Thomas Franke,Karl Ludwig Resch,Alarcos Cieza	2004	39
8	Identifying the concepts contained in outcome measures of clinical trials on breast cancer using the international classification of functioning, disability and health as a reference Thomas Brockow,Katharina Duddeck,Szilvia Geyh,S. R. Schwarzkopf,Martin Weigl,Thomas Franke,Mirjam Brach	2004	32
9	Effect of estradiol on estrogen receptor-α gene expression and activity can be modulated by the ErbB2/PI 3-K/Akt pathway Gerald E. Stoica,Thomas Franke,Maria Moroni,Susette C. Mueller,Elisha Morgan,Mary C. Iann,Abigail Winder,Ronald Reiter,Anton Wellstein,Mary Beth Martin,Adriana Stoica	2003	142
10	PI3K/Akt and apoptosis: size mattersbreakdown → Thomas Franke,Christoph Hornik,Lisa Segev,Grigoriy A Shostak,Chizuru Sugimoto	2003	1014
11	Activation of ERK, Controlled by Rac1 and Cdc42 via Akt, Is Required for Anoikis Wilfrid Rul,Olivier Zugasti,Pierre Roux,Carole Peyssonnaux,Alain Eychène,Thomas Franke,Philippe Lenormand,Philippe Fort,Urszula Hibner	2002	33
12	A Role for Akt in Mediating the Estrogenic Functions of Epidermal Growth Factor and Insulin-Like Growth Factor I¹ Mary Beth Martin,Thomas Franke,Gerald E. Stoica,Pierre Chambon,Benita S. Katzenellenbogen,Bogdan A. Stoica,Michael S. McLemore,Susan E. Olivo,Adriana Stoica	2000	200
13	Regulation of endothelium-derived nitric oxide production by the protein kinase Aktbreakdown → David Fulton,Jean‐Philippe Gratton,Timothy J. McCabe,Jason Fontana,Yasushi Fujio,Kenneth Walsh,Thomas Franke,Andreas Papapetropoulos,William C. Sessa	1999	2179
14	Macrophage Colony-stimulating Factor Promotes Cell Survival through Akt/Protein Kinase B Todd W. Kelley,Mandy M. Graham,Andrea I. Doseff,Richard W. Pomerantz,Sey M. Lau,Michael C. Ostrowski,Thomas Franke,Clay B. Marsh	1999	148
15	Phosphoinositide 3-Kinase Regulation of T Cell Receptor-mediated Interleukin-2 Gene Expression in Normal T Cells Astrid Eder,Lourdes Domínguez,Thomas Franke,Jonathan D. Ashwell	1998	65
16	Role of Akt and c-Jun N-terminal Kinase 2 in Apoptosis Induced by Interleukin-4 Deprivation Ana Cerezo,Carlos Martı́nez-A,Diego Lanzarot,Siegmund Fischer,Thomas Franke,Angelita Rebollo	1998	43
17	PI3K: Downstream AKTion Blocks Apoptosisbreakdown → Thomas Franke,David R. Kaplan,Lewis C. Cantley	1997	1501
18	A Bad kinase makes good Thomas Franke,Lewis C. Cantley	1997	154
19	Frühklassizismus : Position und Opposition : Winckelmann, Mengs, Heinse Helmut Pfotenhauer,Markus Bernauer,Norbert Miller,Thomas Franke	1995	0
20	Die Legionslegaten der römischen Armee in der Zeit von Augustus bis Traian Thomas Franke	1991	3

About Thomas Franke

Thomas Franke is a scholar working on Molecular Biology, Oncology and Cellular and Molecular Neuroscience, having authored 49 papers that have together received 17.6k indexed citations. Recurring topics across this work include PI3K/AKT/mTOR signaling in cancer (21 papers), Protein Kinase Regulation and GTPase Signaling (6 papers), Cell death mechanisms and regulation (6 papers), Genomics, phytochemicals, and oxidative stress (5 papers), Neuroscience and Neuropharmacology Research (5 papers), Cytokine Signaling Pathways and Interactions (5 papers), Cancer-related gene regulation (4 papers) and Multiple Myeloma Research and Treatments (3 papers). The work is most often cited by research in Molecular Biology (11.8k citations), Developmental Neuroscience (516 citations) and Cancer Research (1.8k citations). Thomas Franke has collaborated with scholars based in United States, Canada and France. Frequent co-authors include David R. Kaplan, Lewis C. Cantley, John C. Reed, Michael H. Cardone, Natalie Roy, Eric J. Stanbridge, Guy S. Salvesen, Henning R. Stennicke, Steven M. Frisch and Geoffrey M. Cooper.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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