Kevin M. Ryan

41.9k total citations · 7 hit papers
115 papers, 11.8k citations indexed

About

Kevin M. Ryan is a scholar working on Molecular Biology, Epidemiology and Oncology. According to data from OpenAlex, Kevin M. Ryan has authored 115 papers receiving a total of 11.8k indexed citations (citations by other indexed papers that have themselves been cited), including 75 papers in Molecular Biology, 55 papers in Epidemiology and 39 papers in Oncology. Recurrent topics in Kevin M. Ryan's work include Autophagy in Disease and Therapy (55 papers), Cancer-related Molecular Pathways (36 papers) and Cell death mechanisms and regulation (19 papers). Kevin M. Ryan is often cited by papers focused on Autophagy in Disease and Therapy (55 papers), Cancer-related Molecular Pathways (36 papers) and Cell death mechanisms and regulation (19 papers). Kevin M. Ryan collaborates with scholars based in United Kingdom, United States and Ireland. Kevin M. Ryan's co-authors include Karen H. Vousden, Jim O’Prey, Simon Wilkinson, Mathias T. Rosenfeldt, Andrew C. Phillips, Jayanta Debnath, Noor Gammoh, Diane Crighton, Mary K. Ernst and Nancy R. Rice and has published in prestigious journals such as Nature, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Kevin M. Ryan

114 papers receiving 11.6k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

DRAM, a p53-Induced Modulator of Autophagy, Is Critical for Apoptosis

2006 1.1k citations Diane Crighton, Simon Wilkinson et al. profile →
Autophagy and autophagy-related pathways in cancer

2023 804 citations Kevin M. Ryan et al. profile →
p53 and metabolism

2009 780 citations Karen H. Vousden, Kevin M. Ryan profile →
Role of NF-κB in p53-mediated programmed cell death

2000 652 citations Kevin M. Ryan et al. profile →
Regulation and function of the p53 tumor suppressor protein

2001 591 citations Kevin M. Ryan et al. profile →
p53 status determines the role of autophagy in pancreatic tumour development

2013 576 citations Mathias T. Rosenfeldt, Jim O’Prey et al. profile →
Mitochondrial inner membrane permeabilisation enables mt DNA release during apoptosis

2018 393 citations Joel S. Riley, Giovanni Quarato et al. The EMBO Journal profile →

Peers

Kevin M. Ryan

EPIDE

ONCOL

Kay F. Macleod United States

Andrew Thorburn United States

Xin Jin China

Wei‐Xing Zong United States

Steven F. Bronk United States

Jorge Moscat United States

Patrick Auberger France

Sebastian Wesselborg Germany

Alfredo Criollo Chile

Xiaoxu Wang China

Kay F. Macleod United States

Kevin M. Ryan

6.5k ×0.9

4.3k ×1.0

EPIDE

2.1k ×0.7

ONCOL

1.9k ×0.8

1.2k ×1.0

Citations per year, relative to Kevin M. Ryan Kevin M. Ryan (= 1×) peers Kay F. Macleod

Countries citing papers authored by Kevin M. Ryan

Since Specialization

Citations

This map shows the geographic impact of Kevin M. Ryan's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Kevin M. Ryan with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Kevin M. Ryan more than expected).

Fields of papers citing papers by Kevin M. Ryan

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Kevin M. Ryan. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Kevin M. Ryan. The network helps show where Kevin M. Ryan may publish in the future.

Co-authorship network of co-authors of Kevin M. Ryan

This figure shows the co-authorship network connecting the top 25 collaborators of Kevin M. Ryan. A scholar is included among the top collaborators of Kevin M. Ryan based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Kevin M. Ryan. Kevin M. Ryan is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Durgan, Joanne, et al.. (2023). Lysosome damage triggers direct ATG8 conjugation and ATG2 engagement via non-canonical autophagy. The Journal of Cell Biology. 222(12). 51 indexed citations

Kania, Elżbieta, Jaclyn S. Long, David G. McEwan, et al.. (2023). LRRK2 phosphorylation status and kinase activity regulate (macro)autophagy in a Rab8a/Rab10-dependent manner. Cell Death and Disease. 14(7). 436–436. 10 indexed citations

Long, Jaclyn S., Elżbieta Kania, David G. McEwan, et al.. (2022). ATG7 is a haploinsufficient repressor of tumor progression and promoter of metastasis. Proceedings of the National Academy of Sciences. 119(28). e2113465119–e2113465119. 19 indexed citations

Baudot, Alice D., Victoria M.-Y. Wang, Jim O’Prey, et al.. (2022). Glycan degradation promotes macroautophagy. Proceedings of the National Academy of Sciences. 119(26). e2111506119–e2111506119. 7 indexed citations

Barthet, Valentin J.A., Marcus J.G.W. Ladds, Christos Kiourtis, et al.. (2021). Autophagy suppresses the formation of hepatocyte-derived cancer-initiating ductular progenitor cells in the liver. Science Advances. 7(23). 33 indexed citations

Townsend, Liam, Helen Fogarty, Adam H. Dyer, et al.. (2021). Prolonged elevation of D‐dimer levels in convalescent COVID‐19 patients is independent of the acute phase response. Journal of Thrombosis and Haemostasis. 19(4). 1064–1070. 120 indexed citations

Torretta, Simone, Alessandra Scagliola, Luisa Ricci, et al.. (2020). D-mannose suppresses macrophage IL-1β production. Nature Communications. 11(1). 6343–6343. 163 indexed citations

New, Maria I., Tim Van Acker, Jun-Ichi Sakamaki, et al.. (2019). MDH1 and MPP7 Regulate Autophagy in Pancreatic Ductal Adenocarcinoma. Cancer Research. 79(8). 1884–1898. 29 indexed citations

Baquero, Pablo, Arunima Mukhopadhyay, Rebecca Mitchell, et al.. (2018). Targeting quiescent leukemic stem cells using second generation autophagy inhibitors. Leukemia. 33(4). 981–994. 95 indexed citations

10.

Campbell, Kirsteen J., Sandeep Dhayade, Nicola Ferrari, et al.. (2018). MCL-1 is a prognostic indicator and drug target in breast cancer. Cell Death and Disease. 9(2). 19–19. 144 indexed citations

11.

Riley, Joel S., Giovanni Quarato, Catherine Cloix, et al.. (2018). Mitochondrial inner membrane permeabilisation enables mt DNA release during apoptosis. The EMBO Journal. 37(17). 393 indexed citations breakdown →

12.

Simon, Hans‐Uwe, Robert R. Friis, Stephen W. G. Tait, & Kevin M. Ryan. (2017). Retrograde signaling from autophagy modulates stress responses. Science Signaling. 10(468). 64 indexed citations

13.

O’Prey, Jim, Jun-Ichi Sakamaki, Alice D. Baudot, et al.. (2016). Application of CRISPR/Cas9 to Autophagy Research. Methods in enzymology on CD-ROM/Methods in enzymology. 588. 79–108. 28 indexed citations

14.

Laine, Anni, Harri Sihto, Christophé Côme, et al.. (2013). Senescence Sensitivity of Breast Cancer Cells Is Defined by Positive Feedback Loop between CIP2A and E2F1. Cancer Discovery. 3(2). 182–197. 101 indexed citations

15.

Vigneron, Arnaud, et al.. (2011). MDM2 promotes SUMO-2/3 modification of p53 to modulate transcriptional activity. Cell Cycle. 10(18). 3176–3188. 47 indexed citations

16.

Helgason, G. Vignir, Jim O’Prey, & Kevin M. Ryan. (2010). Oncogene-Induced Sensitization to Chemotherapy-Induced Death Requires Induction as well as Deregulation of E2F1. Cancer Research. 70(10). 4074–4080. 8 indexed citations

17.

Lorin, Séverine, Sylvie Souquère, Gérard Pierron, et al.. (2009). c-Jun NH2-Terminal Kinase Activation Is Essential for DRAM-Dependent Induction of Autophagy and Apoptosis in 2-Methoxyestradiol–Treated Ewing Sarcoma Cells. Cancer Research. 69(17). 6924–6931. 67 indexed citations

18.

Crighton, Diane, Simon Wilkinson, & Kevin M. Ryan. (2007). DRAM Links Autophagy to p53 and Programmed Cell Death. Autophagy. 3(1). 72–74. 168 indexed citations

19.

Wang, Weiguang, James T. Cassidy, Vincent O’Brien, Kevin M. Ryan, & Elaina Collie–Duguid. (2004). Mechanistic and Predictive Profiling of 5-Fluorouracil Resistance in Human Cancer Cells. Cancer Research. 64(22). 8167–8176. 95 indexed citations

20.

Ryan, Kevin M., et al.. (1986). Pulmonary lymphangioleiomyomatosis complicated by pregnancy.. PubMed. 87(10). 277–8, 293. 34 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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