Jim O’Prey

4.7k total citations · 3 hit papers
41 papers, 3.7k citations indexed

About

Jim O’Prey is a scholar working on Molecular Biology, Epidemiology and Oncology. According to data from OpenAlex, Jim O’Prey has authored 41 papers receiving a total of 3.7k indexed citations (citations by other indexed papers that have themselves been cited), including 28 papers in Molecular Biology, 16 papers in Epidemiology and 13 papers in Oncology. Recurrent topics in Jim O’Prey's work include Autophagy in Disease and Therapy (16 papers), Cancer-related Molecular Pathways (12 papers) and Cell death mechanisms and regulation (7 papers). Jim O’Prey is often cited by papers focused on Autophagy in Disease and Therapy (16 papers), Cancer-related Molecular Pathways (12 papers) and Cell death mechanisms and regulation (7 papers). Jim O’Prey collaborates with scholars based in United Kingdom, United States and Germany. Jim O’Prey's co-authors include Kevin M. Ryan, Simon Wilkinson, Paul R. Harrison, Diane Crighton, Tim Crook, Nelofer Syed, Milena Gasco, Ornella Garrone, Paul Smith and Colin Nixon and has published in prestigious journals such as Nature, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Jim O’Prey

40 papers receiving 3.6k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

DRAM, a p53-Induced Modulator of Autophagy, Is Critical for Apoptosis

2006 1.1k citations Diane Crighton, Simon Wilkinson et al. Cell profile →
p53 status determines the role of autophagy in pancreatic tumour development

2013 576 citations Mathias T. Rosenfeldt, Jim O’Prey et al. Nature profile →
Mitochondrial inner membrane permeabilisation enables mt DNA release during apoptosis

2018 393 citations Joel S. Riley, Giovanni Quarato et al. The EMBO Journal profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Jim O’Prey United Kingdom	26	2.3k	1.8k	750	608	476	41	3.7k
Kurt Degenhardt United States	22	3.0k 1.3×	2.1k 1.2×	705 0.9×	713 1.2×	401 0.8×	26	4.5k
Ezgi Tasdemir France	16	1.9k 0.8×	2.1k 1.2×	448 0.6×	426 0.7×	250 0.5×	16	3.4k
Mojgan Djavaheri‐Mergny France	28	1.8k 0.8×	1.4k 0.8×	342 0.5×	542 0.9×	345 0.7×	59	3.3k
Mario P. Tschan Switzerland	38	2.2k 1.0×	1.1k 0.6×	767 1.0×	753 1.2×	407 0.9×	116	3.6k
Brian Beaudoin United States	6	2.6k 1.1×	3.1k 1.7×	468 0.6×	734 1.2×	309 0.6×	6	4.2k
Vassiliki Karantza‐Wadsworth United States	9	2.5k 1.1×	3.0k 1.7×	428 0.6×	716 1.2×	311 0.7×	11	4.2k
Cristina M. Karp United States	11	1.8k 0.8×	2.0k 1.1×	327 0.4×	571 0.9×	190 0.4×	15	3.0k
Shengbing Huang United States	23	1.9k 0.8×	1.2k 0.7×	567 0.8×	447 0.7×	222 0.5×	39	2.9k
Kevin Bray United States	12	2.9k 1.2×	3.4k 1.9×	483 0.6×	923 1.5×	384 0.8×	13	4.8k
Mei Kong United States	25	2.2k 0.9×	1.1k 0.6×	558 0.7×	1.2k 2.0×	351 0.7×	42	3.4k

Countries citing papers authored by Jim O’Prey

Since Specialization

Citations

This map shows the geographic impact of Jim O’Prey's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jim O’Prey with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jim O’Prey more than expected).

Fields of papers citing papers by Jim O’Prey

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jim O’Prey. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jim O’Prey. The network helps show where Jim O’Prey may publish in the future.

Co-authorship network of co-authors of Jim O’Prey

This figure shows the co-authorship network connecting the top 25 collaborators of Jim O’Prey. A scholar is included among the top collaborators of Jim O’Prey based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Jim O’Prey. Jim O’Prey is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Baudot, Alice D., Victoria M.-Y. Wang, Jim O’Prey, et al.. (2022). Glycan degradation promotes macroautophagy. Proceedings of the National Academy of Sciences. 119(26). e2111506119–e2111506119. 7 indexed citations

Beaumatin, Florian, Jim O’Prey, Valentin J.A. Barthet, et al.. (2019). mTORC1 Activation Requires DRAM-1 by Facilitating Lysosomal Amino Acid Efflux. Molecular Cell. 76(1). 163–176.e8. 40 indexed citations

Riley, Joel S., Giovanni Quarato, Catherine Cloix, et al.. (2018). Mitochondrial inner membrane permeabilisation enables mt DNA release during apoptosis. The EMBO Journal. 37(17). 393 indexed citations breakdown →

Fitzwalter, Brent E., Christina G. Towers, Kelly D. Sullivan, et al.. (2018). Autophagy Inhibition Mediates Apoptosis Sensitization in Cancer Therapy by Relieving FOXO3a Turnover. Developmental Cell. 44(5). 555–565.e3. 168 indexed citations

O’Prey, Jim, Jun-Ichi Sakamaki, Alice D. Baudot, et al.. (2016). Application of CRISPR/Cas9 to Autophagy Research. Methods in enzymology on CD-ROM/Methods in enzymology. 588. 79–108. 28 indexed citations

Baudot, Alice D., Diane Crighton, Jim O’Prey, et al.. (2016). p53 directly regulates the glycosidase FUCA1 to promote chemotherapy-induced cell death. Cell Cycle. 15(17). 2299–2308. 25 indexed citations

O’Prey, Jim, Jaclyn S. Long, Florian Beaumatin, et al.. (2015). DRAM-3 modulates autophagy and promotes cell survival in the absence of glucose. Cell Death and Differentiation. 22(10). 1714–1726. 21 indexed citations

Rosenfeldt, Mathias T., Jim O’Prey, Jennifer P. Morton, et al.. (2013). p53 status determines the role of autophagy in pancreatic tumour development. Nature. 504(7479). 296–300. 576 indexed citations breakdown →

O’Prey, Jim, et al.. (2012). DRAM-1 encodes multiple isoforms that regulate autophagy. Autophagy. 8(1). 18–28. 45 indexed citations

10.

Wilkinson, Simon, et al.. (2011). The cyclin-dependent kinase PITSLRE/CDK11 is required for successful autophagy. Autophagy. 7(11). 1295–1301. 32 indexed citations

11.

Helgason, G. Vignir, Jim O’Prey, & Kevin M. Ryan. (2010). Oncogene-Induced Sensitization to Chemotherapy-Induced Death Requires Induction as well as Deregulation of E2F1. Cancer Research. 70(10). 4074–4080. 8 indexed citations

12.

Fricker, Michael, Jim O’Prey, Aviva M. Tolkovsky, & Kevin M. Ryan. (2010). Phosphorylation of Puma modulates its apoptotic function by regulating protein stability. Cell Death and Disease. 1(7). e59–e59. 54 indexed citations

13.

Wilkinson, Simon, Jim O’Prey, Michael Fricker, & Kevin M. Ryan. (2009). Hypoxia-selective macroautophagy and cell survival signaled by autocrine PDGFR activity. Genes & Development. 23(11). 1283–1288. 59 indexed citations

14.

Bell, Helen, Christine Dufès, Jim O’Prey, et al.. (2007). A p53-derived apoptotic peptide derepresses p73 to cause tumor regression in vivo. Journal of Clinical Investigation. 117(4). 1008–1018. 59 indexed citations

15.

Crighton, Diane, Jim O’Prey, Helen Bell, & Kevin M. Ryan. (2007). p73 regulates DRAM-independent autophagy that does not contribute to programmed cell death. Cell Death and Differentiation. 14(6). 1071–1079. 82 indexed citations

16.

Bell, Laura A., Jim O’Prey, & Kevin M. Ryan. (2006). DNA-binding independent cell death from a minimal proapoptotic region of E2F-1. Oncogene. 25(41). 5656–5663. 28 indexed citations

17.

Crighton, Diane, Simon Wilkinson, Jim O’Prey, et al.. (2006). DRAM, a p53-Induced Modulator of Autophagy, Is Critical for Apoptosis. Cell. 126(1). 121–134. 1093 indexed citations breakdown →

18.

Leslie, Nicholas R., Jim O’Prey, Chris Bartholomew, & Paul R. Harrison. (1998). An Activating Mutation in the Kit Receptor Abolishes the Stroma Requirement for Growth of ELM Erythroleukemia Cells, But Does Not Prevent Their Differentiation in Response to Erythropoietin. Blood. 92(12). 4798–4807. 2 indexed citations

19.

O’Prey, Jim & Paul R. Harrison. (1995). Tissue-specific regulation of the rabbit 15-lipoxygenase gene in erythroid cells by a transcriptional silencer. Nucleic Acids Research. 23(18). 3664–3672. 21 indexed citations

20.

Fleming, Janis, B Thiele, John Chester, et al.. (1989). The complete sequence of the rabbit erythroid cell-specific 15-lipoxygenase mRNA: comparison of the predicted amino acid sequence of the erythrocyte lipoxygenase with other lipoxygenases. Gene. 79(1). 181–188. 83 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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