Kenneth S. Lown

4.4k total citations · 1 hit paper
23 papers, 3.0k citations indexed

About

Kenneth S. Lown is a scholar working on Pharmacology, Oncology and Pediatrics, Perinatology and Child Health. According to data from OpenAlex, Kenneth S. Lown has authored 23 papers receiving a total of 3.0k indexed citations (citations by other indexed papers that have themselves been cited), including 13 papers in Pharmacology, 11 papers in Oncology and 4 papers in Pediatrics, Perinatology and Child Health. Recurrent topics in Kenneth S. Lown's work include Pharmacogenetics and Drug Metabolism (12 papers), Drug Transport and Resistance Mechanisms (9 papers) and Renal Transplantation Outcomes and Treatments (4 papers). Kenneth S. Lown is often cited by papers focused on Pharmacogenetics and Drug Metabolism (12 papers), Drug Transport and Resistance Mechanisms (9 papers) and Renal Transplantation Outcomes and Treatments (4 papers). Kenneth S. Lown collaborates with scholars based in United States, United Kingdom and Canada. Kenneth S. Lown's co-authors include Paul B. Watkins, Phyllissa Schmiedlin‐Ren, D. Kim Turgeon, Kenneth E. Thummel, Joseph C. Kolars, Steven Wrighton, Paul B. Watkins, Mary F. Paine, Robert M. Merion and Alan B. Leichtman and has published in prestigious journals such as Journal of Clinical Investigation, Gastroenterology and Molecular Pharmacology.

In The Last Decade

Kenneth S. Lown

23 papers receiving 2.9k citations

Hit Papers

align trajectories sort by overperformance

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Role of intestinal P-glycoprotein (mdr1) in interpatient variation in the oral bioavailability of cyclosporine*

1997 576 citations Kenneth S. Lown, Robert R. Mayo et al. Clinical Pharmacology & Therapeutics profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Kenneth S. Lown United States	19	1.7k	1.5k	878	369	331	23	3.0k
Phyllissa Schmiedlin‐Ren United States	19	1.3k 0.7×	1.3k 0.8×	739 0.8×	354 1.0×	242 0.7×	31	2.5k
Vincent J. Wacher United States	18	1.3k 0.8×	1.9k 1.2×	1.2k 1.3×	457 1.2×	313 0.9×	25	3.1k
Cynthia Brimer United States	9	1.7k 1.0×	1.5k 1.0×	827 0.9×	581 1.6×	124 0.4×	9	3.0k
Kenji Otsubo Japan	31	1.2k 0.7×	1.8k 1.2×	1.2k 1.3×	812 2.2×	358 1.1×	71	3.9k
Yvonne S. Lin United States	32	1.9k 1.1×	1.4k 0.9×	898 1.0×	849 2.3×	296 0.9×	65	4.0k
Paul B. Watkins United States	15	956 0.6×	1.0k 0.7×	531 0.6×	227 0.6×	153 0.5×	20	1.7k
Mark VandenBranden United States	24	2.4k 1.4×	1.3k 0.9×	492 0.6×	615 1.7×	361 1.1×	28	3.1k
Lydiane Pichard France	18	1.3k 0.8×	808 0.5×	323 0.4×	450 1.2×	191 0.6×	33	2.2k
George K. Dresser Canada	28	1.4k 0.8×	1.5k 0.9×	886 1.0×	518 1.4×	584 1.8×	59	3.9k
Oliver von Richter Germany	25	1.5k 0.9×	2.9k 1.9×	1.8k 2.0×	973 2.6×	326 1.0×	66	4.6k

Countries citing papers authored by Kenneth S. Lown

Since Specialization

Citations

This map shows the geographic impact of Kenneth S. Lown's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Kenneth S. Lown with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Kenneth S. Lown more than expected).

Fields of papers citing papers by Kenneth S. Lown

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Kenneth S. Lown. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Kenneth S. Lown. The network helps show where Kenneth S. Lown may publish in the future.

Co-authorship network of co-authors of Kenneth S. Lown

This figure shows the co-authorship network connecting the top 25 collaborators of Kenneth S. Lown. A scholar is included among the top collaborators of Kenneth S. Lown based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Kenneth S. Lown. Kenneth S. Lown is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

1.

Watkins, Paul B., Steven Wrighton, Jeffrey L. Barnett, et al.. (2019). Interpatient heterogeneity in expression of CYP3A4 and CYP3A5 in small bowel: Lack of prediction by the erythromycin breath test. Carolina Digital Repository (University of North Carolina at Chapel Hill). 11 indexed citations

2.

Jaffe, Craig A., D. Kim Turgeon, Kenneth S. Lown, Roberta DeMott-Friberg, & Paul B. Watkins. (2002). Growth hormone secretion pattern is an independent regulator of growth hormone actions in humans. American Journal of Physiology-Endocrinology and Metabolism. 283(5). E1008–E1015. 107 indexed citations

3.

Lown, Kenneth S., et al.. (1999). Effects of a chargrilled meat diet on expression of CYP3A, CYP1A, and P-glycoprotein levels in healthy volunteers. Gastroenterology. 117(1). 89–98. 101 indexed citations

4.

Hall, Stephen D., Kenneth E. Thummel, Paul B. Watkins, et al.. (1999). Symposium Article: Molecular and Physical Mechanisms of First-Pass Extraction. Drug Metabolism and Disposition. 27(2). 161–166. 86 indexed citations

5.

Lown, Kenneth S.. (1998). Drug-induced liver disease. Current Opinion in Gastroenterology. 14(3). 208–214. 7 indexed citations

6.

Lown, Kenneth S., Mita Ghosh, & Paul B. Watkins. (1998). Sequences of intestinal and hepatic cytochrome P450 3A4 cDNAs are identical.. PubMed. 26(2). 185–7. 50 indexed citations

7.

Lown, Kenneth S., David G. Bailey, Robert J. Fontana, et al.. (1997). Grapefruit juice increases felodipine oral availability in humans by decreasing intestinal CYP3A protein expression.. Journal of Clinical Investigation. 99(10). 2545–2553. 495 indexed citations

8.

Schmiedlin‐Ren, Phyllissa, Kenneth E. Thummel, Jeannine M. Fisher, et al.. (1997). Expression of Enzymatically Active CYP3A4 by Caco-2 Cells Grown on Extracellular Matrix-Coated Permeable Supports in the Presence of 1α,25-Dihydroxyvitamin D3. Molecular Pharmacology. 51(5). 741–754. 276 indexed citations

9.

Lown, Kenneth S., Robert R. Mayo, Alan B. Leichtman, et al.. (1997). Role of intestinal P-glycoprotein (mdr1) in interpatient variation in the oral bioavailability of cyclosporine*. Clinical Pharmacology & Therapeutics. 62(3). 248–260. 576 indexed citations breakdown →

10.

Schmiedlin‐Ren, Phyllissa, David Edwards, Michael E. Fitzsimmons, et al.. (1997). Mechanisms of enhanced oral availability of CYP3A4 substrates by grapefruit constituents. Decreased enterocyte CYP3A4 concentration and mechanism-based inactivation by furanocoumarins.. PubMed. 25(11). 1228–33. 108 indexed citations

11.

Magee, John C., Jonathan S. Bromberg, Darrell A. Campbell, et al.. (1996). Update of the Adult and Pediatric Liver Transplant Program at the University of Michigan.. PubMed. 203–16. 4 indexed citations

12.

Lown, Kenneth S., et al.. (1996). Selective expression of CYP3A5 and not CYP3A4 in human blood. Pharmacogenetics. 6(5). 379–385. 38 indexed citations

13.

Lown, Kenneth S., Kenneth E. Thummel, Patrick E. Benedict, et al.. (1995). The erythromycin breath test predicts the clearance of midazolam*. Clinical Pharmacology & Therapeutics. 57(1). 16–24. 108 indexed citations

14.

Kolars, Joseph C., Kenneth S. Lown, Phyllissa Schmiedlin‐Ren, et al.. (1994). CYP3A gene expression in human gut epithelium. Pharmacogenetics. 4(5). 247–259. 321 indexed citations

15.

Turgeon, D. Kim, Alan B. Leichtman, Robert Schmouder, et al.. (1994). PREDICTION OF INTERPATIENT AND INTRAPATIENT VARIATION IN OG 37–325 DOSING REQUIREMENTS BY THE ERYTHROMYCIN BREATH TEST. Transplantation. 57(12). 1736–1741. 19 indexed citations

16.

Turgeon, D. Kim, Alan B. Leichtman, Kenneth S. Lown, et al.. (1994). P450 3A activity and cyclosporine dosing in kidney and heart transplant recipients. Clinical Pharmacology & Therapeutics. 56(3). 253–260. 47 indexed citations

17.

Lown, Kenneth S., Joseph C. Kolars, Kenneth E. Thummel, et al.. (1994). Interpatient heterogeneity in expression of CYP3A4 and CYP3A5 in small bowel. Lack of prediction by the erythromycin breath test.. Drug Metabolism and Disposition. 22(6). 947–955. 87 indexed citations

18.

Turgeon, D. Kim, Alan B. Leichtman, Robert Schmouder, et al.. (1994). PREDICTION OF INTERPATIENT AND INTRAPATIENT VARIATION IN OG 37–325 DOSING REQUIREMENTS BY THE ERYTHROMYCIN BREATH TEST. Transplantation. 57(12). 1736–1741. 15 indexed citations

19.

Watkins, Paul B., D. Kim Turgeon, Paul Saenger, et al.. (1992). Comparison of urinary 6-β-cortisol and the erythromycin breath test as measures of hepatic P450IIIA (CYP3A) activity. Clinical Pharmacology & Therapeutics. 52(3). 265–273. 115 indexed citations

20.

Lown, Kenneth S., Joseph C. Kolars, D. Kim Turgeon, et al.. (1992). The erythromycin breath test selectively measures P450IIIA in patients with severe liver disease. Clinical Pharmacology & Therapeutics. 51(3). 229–238. 108 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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