Michael E. Fitzsimmons

833 total citations
16 papers, 466 citations indexed

About

Michael E. Fitzsimmons is a scholar working on Molecular Biology, Organic Chemistry and Oncology. According to data from OpenAlex, Michael E. Fitzsimmons has authored 16 papers receiving a total of 466 indexed citations (citations by other indexed papers that have themselves been cited), including 6 papers in Molecular Biology, 4 papers in Organic Chemistry and 3 papers in Oncology. Recurrent topics in Michael E. Fitzsimmons's work include Pharmacogenetics and Drug Metabolism (3 papers), Hormonal and reproductive studies (3 papers) and Glutathione Transferases and Polymorphisms (2 papers). Michael E. Fitzsimmons is often cited by papers focused on Pharmacogenetics and Drug Metabolism (3 papers), Hormonal and reproductive studies (3 papers) and Glutathione Transferases and Polymorphisms (2 papers). Michael E. Fitzsimmons collaborates with scholars based in United States and Japan. Michael E. Fitzsimmons's co-authors include Jerry M. Collins, Patrick M. Woster, M.W. Anders, Paul F. Hollenberg, Paul B. Watkins, Phyllissa Schmiedlin‐Ren, Kan He, Jeannine M. Fisher, Kenneth S. Lown and Kenneth E. Thummel and has published in prestigious journals such as Environmental Science & Technology, Biochemistry and Journal of Pharmacology and Experimental Therapeutics.

In The Last Decade

Michael E. Fitzsimmons

16 papers receiving 451 citations

Peers

Michael E. Fitzsimmons

PHARM

ONCOL

PPCH

Leslie M. Tompkins United States

Jane Sayi Tanzania

P E Sanders United States

I. Gardner United Kingdom

Cornelia M. Smith United States

Jignesh Patel United States

Lilly Xu United States

Otito F. Iwuchukwu United States

Dorothee Frank Germany

Darryl Gilbert United States

Leslie M. Tompkins United States

Michael E. Fitzsimmons

316 ×1.8

PHARM

164 ×1.1

ONCOL

151 ×1.2

46 ×0.4

68 ×1.0

PPCH

Citations per year, relative to Michael E. Fitzsimmons Michael E. Fitzsimmons (= 1×) peers Leslie M. Tompkins

Countries citing papers authored by Michael E. Fitzsimmons

Since Specialization

Citations

This map shows the geographic impact of Michael E. Fitzsimmons's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Michael E. Fitzsimmons with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Michael E. Fitzsimmons more than expected).

Fields of papers citing papers by Michael E. Fitzsimmons

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Michael E. Fitzsimmons. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Michael E. Fitzsimmons. The network helps show where Michael E. Fitzsimmons may publish in the future.

Co-authorship network of co-authors of Michael E. Fitzsimmons

This figure shows the co-authorship network connecting the top 25 collaborators of Michael E. Fitzsimmons. A scholar is included among the top collaborators of Michael E. Fitzsimmons based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Michael E. Fitzsimmons. Michael E. Fitzsimmons is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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16 of 16 papers shown

Fitch, William L., Steven M. Smith, Michael S. Saporito, et al.. (2023). Complex Metabolism of the Novel Neurosteroid, Ganaxolone, in Humans: A Unique Challenge for Metabolites in Safety Testing Assessment. Drug Metabolism and Disposition. 51(6). 753–763. 7 indexed citations

Khetarpal, Vinod, Steven R. Ash, Michael E. Fitzsimmons, et al.. (2021). Pharmacokinetics and metabolic disposition of a potent and selective kynurenine monooxygenase inhibitor, CHDI-340246, in laboratory animals. Xenobiotica. 51(10). 1155–1180. 1 indexed citations

Hollenberg, Paul F., David Edwards, Kan He, et al.. (2019). Mechanisms of enhanced oral availability of CYP3A4 substrates by grapefruit constituents: Decreased enterocyte CYP3A4 concentration and mechanism-based inactivation by furanocoumarins. UNC Libraries. 21 indexed citations

Mansbach, Robert S., et al.. (2017). Absorption, Distribution, and Excretion of 14C-APX001 after Single-Dose Administration to Rats and Monkeys. Open Forum Infectious Diseases. 4(suppl_1). S472–S472. 17 indexed citations

Fitzsimmons, Michael E., Gang Sun, Vladimir Kuksa, & Michael Reid. (2017). Disposition, profiling and identification of emixustat and its metabolites in humans. Xenobiotica. 48(6). 592–604. 10 indexed citations

Ohtsu, Yoshiaki, Jacqueline A. Gibbons, Katsuhiro Suzuki, et al.. (2016). Absorption, Distribution, Metabolism, and Excretion of the Androgen Receptor Inhibitor Enzalutamide in Rats and Dogs. European Journal of Drug Metabolism and Pharmacokinetics. 42(4). 611–626. 9 indexed citations

Kinsella, Timothy J., et al.. (1998). Preclinical evaluation of 5-iodo-2-pyrimidinone-2'-deoxyribose as a prodrug for 5-iodo-2'-deoxyuridine-mediated radiosensitization in mouse and human tissues.. PubMed. 4(1). 99–109. 21 indexed citations

Fitzsimmons, Michael E. & Jerry M. Collins. (1997). Selective biotransformation of the human immunodeficiency virus protease inhibitor saquinavir by human small-intestinal cytochrome P4503A4: potential contribution to high first-pass metabolism.. PubMed. 25(2). 256–66. 199 indexed citations

Schmiedlin‐Ren, Phyllissa, David Edwards, Michael E. Fitzsimmons, et al.. (1997). Mechanisms of enhanced oral availability of CYP3A4 substrates by grapefruit constituents. Decreased enterocyte CYP3A4 concentration and mechanism-based inactivation by furanocoumarins.. PubMed. 25(11). 1228–33. 108 indexed citations

10.

Fitzsimmons, Michael E., Colin Thorpe, & M. W. Anders. (1995). Medium-Chain Acyl-CoA Dehydrogenase- and Enoyl-CoA Hydratase-Dependent Bioactivation of 5,6-Dichloro-4-thia-5-hexenoyl-CoA. Biochemistry. 34(13). 4276–4286. 9 indexed citations

11.

Fitzsimmons, Michael E., Raymond B. Baggs, & M. W. Anders. (1994). Nephrotoxicity and hepatotoxicity of 5,6-dichloro-4-thia-5-hexenoic acid: evidence for fatty acid beta-oxidation-dependent bioactivation.. Journal of Pharmacology and Experimental Therapeutics. 271(1). 515–523. 6 indexed citations

12.

Fitzsimmons, Michael E. & M.W. Anders. (1993). Fatty acid .beta.-oxidation-dependent bioactivation of halogenated thiaalkanoic acids in isolated rat hepatocytes. Chemical Research in Toxicology. 6(5). 662–668. 6 indexed citations

13.

Fitzsimmons, Michael E., et al.. (1991). Stereochemistry of the Microsomal Glutathione S-Transferase-Catalyzed Addition of Glutathione to Chlorotrifluoroethene in Isolated Rat Hepatocytes. Advances in experimental medicine and biology. 283. 289–293. 2 indexed citations

14.

Fitzsimmons, Michael E., et al.. (1991). Stereochemistry of the microsomal glutathione S-transferase catalyzed addition of glutathione to chlorotrifluoroethene. Biochemistry. 30(3). 717–721. 30 indexed citations

15.

Fitzsimmons, Michael E. & M.W. Anders. (1991). Fatty Acid β-Oxidation-Dependent Bioactivation of 5,6-Dichloro-4-Thia-5-Hexenoate and Analogs in Isolated Rat Hepatocytes. Advances in experimental medicine and biology. 283. 281–284. 2 indexed citations

16.

Lukasewycz, Marta T., et al.. (1989). Analysis of inorganic and organic chloramines: derivatization with 2-mercaptobenzothiazole. Environmental Science & Technology. 23(2). 196–199. 18 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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