John D. Schuetz

24.2k total citations · 3 hit papers
196 papers, 19.4k citations indexed

About

John D. Schuetz is a scholar working on Oncology, Molecular Biology and Pharmacology. According to data from OpenAlex, John D. Schuetz has authored 196 papers receiving a total of 19.4k indexed citations (citations by other indexed papers that have themselves been cited), including 134 papers in Oncology, 73 papers in Molecular Biology and 39 papers in Pharmacology. Recurrent topics in John D. Schuetz's work include Drug Transport and Resistance Mechanisms (122 papers), Pharmacogenetics and Drug Metabolism (35 papers) and Pharmacological Effects and Toxicity Studies (25 papers). John D. Schuetz is often cited by papers focused on Drug Transport and Resistance Mechanisms (122 papers), Pharmacogenetics and Drug Metabolism (35 papers) and Pharmacological Effects and Toxicity Studies (25 papers). John D. Schuetz collaborates with scholars based in United States, Japan and Netherlands. John D. Schuetz's co-authors include Erin G. Schuetz, Mary V. Relling, Brian P. Sorrentino, Sheng Zhou, Kazuto Yasuda, Daxi Sun, Partha Krishnamurthy, Janardhan Sampath, Stephen C. Strom and Philip S. Guzelian and has published in prestigious journals such as Nature, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

John D. Schuetz

193 papers receiving 18.9k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype

2001 1.8k citations Sheng Zhou, John D. Schuetz et al. Nature Medicine profile →
Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression

2001 1.8k citations John D. Schuetz et al. profile →
The Stem Cell Marker Bcrp/ABCG2 Enhances Hypoxic Cell Survival through Interactions with Heme

2004 520 citations Partha Krishnamurthy, Sheng Zhou et al. Journal of Biological Chemistry profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
John D. Schuetz United States	74	10.9k	6.6k	4.7k	4.3k	2.1k	196	19.4k
Alex Sparreboom United States	86	14.2k 1.3×	8.9k 1.3×	3.3k 0.7×	3.3k 0.8×	1.3k 0.6×	408	24.4k
Erin G. Schuetz United States	77	9.7k 0.9×	4.7k 0.7×	9.8k 2.1×	4.0k 0.9×	1.6k 0.8×	198	19.9k
Kathleen M. Giacomini United States	66	7.5k 0.7×	5.3k 0.8×	2.4k 0.5×	4.0k 0.9×	1.4k 0.7×	289	15.8k
Alfred H. Schinkel Netherlands	88	22.2k 2.0×	8.7k 1.3×	4.0k 0.8×	10.6k 2.5×	3.9k 1.9×	297	30.8k
Ken‐ichi Inui Japan	75	10.5k 1.0×	5.3k 0.8×	1.7k 0.4×	5.8k 1.3×	2.4k 1.1×	502	19.7k
George L. Scheffer Netherlands	62	10.5k 1.0×	5.3k 0.8×	1.1k 0.2×	4.1k 1.0×	2.7k 1.3×	141	14.9k
Els Wagenaar Netherlands	53	10.1k 0.9×	4.3k 0.7×	1.8k 0.4×	5.0k 1.2×	1.8k 0.9×	97	14.1k
Susan P.C. Cole Canada	70	15.8k 1.4×	8.7k 1.3×	1.2k 0.2×	5.5k 1.3×	3.4k 1.6×	245	21.8k
Olaf van Tellingen Netherlands	64	10.0k 0.9×	5.3k 0.8×	1.8k 0.4×	3.8k 0.9×	1.2k 0.5×	238	16.1k
Dietrich Keppler Germany	85	14.0k 1.3×	5.6k 0.8×	3.6k 0.8×	6.9k 1.6×	4.3k 2.0×	261	22.5k

Countries citing papers authored by John D. Schuetz

Since Specialization

Citations

This map shows the geographic impact of John D. Schuetz's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by John D. Schuetz with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites John D. Schuetz more than expected).

Fields of papers citing papers by John D. Schuetz

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by John D. Schuetz. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by John D. Schuetz. The network helps show where John D. Schuetz may publish in the future.

Co-authorship network of co-authors of John D. Schuetz

This figure shows the co-authorship network connecting the top 25 collaborators of John D. Schuetz. A scholar is included among the top collaborators of John D. Schuetz based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with John D. Schuetz. John D. Schuetz is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Budhraja, Amit, J.A. Lynch, Kathryn G. Roberts, et al.. (2020). The Heme-Regulated Inhibitor Pathway Modulates Susceptibility of Poor Prognosis B-Lineage Acute Leukemia to BH3-Mimetics. Molecular Cancer Research. 19(4). 636–650. 12 indexed citations

Vo, BaoHan T., Jingjing Liu, Beisi Xu, et al.. (2020). An ABC Transporter Drives Medulloblastoma Pathogenesis by Regulating Sonic Hedgehog Signaling. Cancer Research. 80(7). 1524–1537. 7 indexed citations

Fukuda, Yu, Yao Wang, Shangli Lian, et al.. (2017). Upregulated heme biosynthesis, an exploitable vulnerability in MYCN-driven leukemogenesis. JCI Insight. 2(15). 36 indexed citations

Kusuhara, Hiroyuki, et al.. (2017). Investigation of the Importance of Multidrug Resistance-Associated Protein 4 (Mrp4/ Abcc4 ) in the Active Efflux of Anionic Drugs Across the Blood–Brain Barrier. Journal of Pharmaceutical Sciences. 106(9). 2566–2575. 25 indexed citations

Moon, Changsuk, Weiqiang Zhang, Aixia Ren, et al.. (2015). Compartmentalized Accumulation of cAMP near Complexes of Multidrug Resistance Protein 4 (MRP4) and Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Contributes to Drug-induced Diarrhea. Journal of Biological Chemistry. 290(18). 11246–11257. 30 indexed citations

Morfouace, Marie, Satish Cheepala, Sadhana Jackson, et al.. (2015). ABCG2 Transporter Expression Impacts Group 3 Medulloblastoma Response to Chemotherapy. Cancer Research. 75(18). 3879–3889. 29 indexed citations

Lynch, J.A., Yu Fukuda, Partha Krishnamurthy, Guoqing Du, & John D. Schuetz. (2009). Cell Survival under Stress Is Enhanced by a Mitochondrial ATP-Binding Cassette Transporter That Regulates Hemoproteins. Cancer Research. 69(13). 5560–5567. 48 indexed citations

Matsushima, Soichiro, Kazuya Maeda, Hisamitsu Hayashi, et al.. (2008). Involvement of Multiple Efflux Transporters in Hepatic Disposition of Fexofenadine. Molecular Pharmacology. 73(5). 1474–1483. 83 indexed citations

Ose, Atsushi, Hiroyuki Kusuhara, Kenzo Yamatsugu, et al.. (2008). Limited Brain Distribution of [3R,4R,5S ]-4-Acetamido-5-amino-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylate Phosphate (Ro 64-0802), a Pharmacologically Active Form of Oseltamivir, by Active Efflux across the Blood-Brain Barrier Mediated by Organic Anion Transporter 3 (Oat3/Slc22a8) and Multidrug Resistance-Associated Protein 4 (Mrp4/Abcc4). Drug Metabolism and Disposition. 37(2). 315–321. 100 indexed citations

10.

Yamada, Akihiro, Kazuya Maeda, Emi Kamiyama, et al.. (2007). Multiple Human Isoforms of Drug Transporters Contribute to the Hepatic and Renal Transport of Olmesartan, a Selective Antagonist of the Angiotensin II AT1-Receptor. Drug Metabolism and Disposition. 35(12). 2166–2176. 111 indexed citations

11.

Takenaka, Kazumasa, James P. Morgan, George L. Scheffer, et al.. (2007). Substrate Overlap between Mrp4 and Abcg2/Bcrp Affects Purine Analogue Drug Cytotoxicity and Tissue Distribution. Cancer Research. 67(14). 6965–6972. 73 indexed citations

12.

Li, Chunying, Partha Krishnamurthy, Xue Wang, et al.. (2007). Spatiotemporal Coupling of cAMP Transporter to CFTR Chloride Channel Function in the Gut Epithelia. Cell. 131(5). 940–951. 158 indexed citations

13.

Kleemann, P. P., et al.. (2006). Multidrug-resistance-associated protein 1 (Mrp1) is probably not required for murine Th cell activation. International Immunology. 18(11). 1603–1606. 3 indexed citations

14.

Hasegawa, Maki, Hiroyuki Kusuhara, Masashi Adachi, et al.. (2006). Multidrug Resistance–Associated Protein 4 Is Involved in the Urinary Excretion of Hydrochlorothiazide and Furosemide. Journal of the American Society of Nephrology. 18(1). 37–45. 97 indexed citations

15.

Yamaguchi, Hiroaki, Ingrid van der Heijden, Peter R. Wielinga, et al.. (2006). cGMP transport by vesicles from human and mouse erythrocytes. FEBS Journal. 274(2). 439–450. 55 indexed citations

16.

Leggas, Markos, Masashi Adachi, George L. Scheffer, et al.. (2004). Mrp4 Confers Resistance to Topotecan and Protects the Brain from Chemotherapy. Molecular and Cellular Biology. 24(17). 7612–7621. 321 indexed citations

17.

Wagner, Martin, Peter Fickert, Gernot Zollner, et al.. (2003). Role of farnesoid X receptor in determining hepatic ABC transporter expression and liver injury in bile duct-ligated mice. Gastroenterology. 125(3). 825–838. 216 indexed citations

18.

Adachi, Masashi, Glen Reid, & John D. Schuetz. (2002). Therapeutic and biological importance of getting nucleotides out of cells: a case for the ABC transporters, MRP4 and 5. Advanced Drug Delivery Reviews. 54(10). 1333–1342. 44 indexed citations

19.

Wielinga, Peter R., Glen Reid, Ingrid van der Heijden, et al.. (2002). Thiopurine Metabolism and Identification of the Thiopurine Metabolites Transported by MRP4 and MRP5 Overexpressed in Human Embryonic Kidney Cells. Molecular Pharmacology. 62(6). 1321–1331. 149 indexed citations

20.

Zhou, Sheng, John D. Schuetz, Kevin D. Bunting, et al.. (2001). The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype. Nature Medicine. 7(9). 1028–1034. 1846 indexed citations breakdown →

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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