Alejandro Soto–Gutiérrez

8.0k total citations · 2 hit papers
105 papers, 5.8k citations indexed

About

Alejandro Soto–Gutiérrez is a scholar working on Surgery, Hepatology and Molecular Biology. According to data from OpenAlex, Alejandro Soto–Gutiérrez has authored 105 papers receiving a total of 5.8k indexed citations (citations by other indexed papers that have themselves been cited), including 64 papers in Surgery, 54 papers in Hepatology and 37 papers in Molecular Biology. Recurrent topics in Alejandro Soto–Gutiérrez's work include Liver physiology and pathology (44 papers), Pluripotent Stem Cells Research (30 papers) and Organ Transplantation Techniques and Outcomes (27 papers). Alejandro Soto–Gutiérrez is often cited by papers focused on Liver physiology and pathology (44 papers), Pluripotent Stem Cells Research (30 papers) and Organ Transplantation Techniques and Outcomes (27 papers). Alejandro Soto–Gutiérrez collaborates with scholars based in United States, Japan and Sweden. Alejandro Soto–Gutiérrez's co-authors include Naoya Kobayashi, Hiroshi Yagi, Martin L. Yarmush, Nalu Navarro–Álvarez, Yuko Kitagawa, Ronald G. Tompkins, Ira J. Fox, Arno W. Tilles, Yaakov Nahmias and Biju Parekkadan and has published in prestigious journals such as Journal of Clinical Investigation, Nature Medicine and SHILAP Revista de lepidopterología.

In The Last Decade

Alejandro Soto–Gutiérrez

103 papers receiving 5.7k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Organ reengineering through development of a transplantable recellularized liver graft using decellularized liver matrix

2010 1.0k citations Alejandro Soto–Gutiérrez, Hiroshi Yagi et al. profile →
Mesenchymal Stem Cells: Mechanisms of Immunomodulation and Homing

2010 552 citations Hiroshi Yagi, Alejandro Soto–Gutiérrez et al. profile →

Peers

Alejandro Soto–Gutiérrez

SURGE

HEPAT

BIOMA

Ira J. Fox United States

Motokuni Aoki Japan

Yun‐Wen Zheng Japan

Jörg C. Gerlach United States

Ji Bao China

Hiroyuki Koike Japan

Anne‐Christine Bay‐Jensen Denmark

A. M. James Shapiro Canada

Yingying Jing China

Shin Enosawa Japan

Ira J. Fox United States

Alejandro Soto–Gutiérrez

4.9k ×1.4

SURGE

3.6k ×1.9

HEPAT

1.8k ×1.0

389 ×0.3

BIOMA

651 ×0.5

Citations per year, relative to Alejandro Soto–Gutiérrez Alejandro Soto–Gutiérrez (= 1×) peers Ira J. Fox

Countries citing papers authored by Alejandro Soto–Gutiérrez

Since Specialization

Citations

This map shows the geographic impact of Alejandro Soto–Gutiérrez's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Alejandro Soto–Gutiérrez with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Alejandro Soto–Gutiérrez more than expected).

Fields of papers citing papers by Alejandro Soto–Gutiérrez

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Alejandro Soto–Gutiérrez. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Alejandro Soto–Gutiérrez. The network helps show where Alejandro Soto–Gutiérrez may publish in the future.

Co-authorship network of co-authors of Alejandro Soto–Gutiérrez

This figure shows the co-authorship network connecting the top 25 collaborators of Alejandro Soto–Gutiérrez. A scholar is included among the top collaborators of Alejandro Soto–Gutiérrez based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Alejandro Soto–Gutiérrez. Alejandro Soto–Gutiérrez is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

DeBiasio, Richard, Rodrigo M. Florentino, Jacquelyn A. Brown, et al.. (2024). Comparison of wild-type and high-risk PNPLA3 variants in a human biomimetic liver microphysiology system for metabolic dysfunction-associated steatotic liver disease precision therapy. Frontiers in Cell and Developmental Biology. 12. 1423936–1423936. 7 indexed citations

Hu, Zhiping, Takeshi Kurihara, Edgar N. Tafaleng, et al.. (2023). Evaluation of Human Hepatocyte Drug Metabolism Carrying High-Risk or Protection-Associated Liver Disease Genetic Variants. International Journal of Molecular Sciences. 24(17). 13406–13406. 8 indexed citations

Liu, Silvia, Yanping Yu, Bao‐Guo Ren, et al.. (2023). Long-read single-cell sequencing reveals expressions of hypermutation clusters of isoforms in human liver cancer cells. eLife. 12. 2 indexed citations

Higashi, Hisanobu, Hiroshi Yagi, Kohei Kuroda, et al.. (2021). Transplantation of bioengineered liver capable of extended function in a preclinical liver failure model. American Journal of Transplantation. 22(3). 731–744. 13 indexed citations

Tafaleng, Edgar N., Amitava Mukherjee, Aaron Bell, et al.. (2021). Hepatocyte Nuclear Factor 4 alpha 2 Messenger RNA Reprograms Liver‐Enriched Transcription Factors and Functional Proteins in End‐Stage Cirrhotic Human Hepatocytes. Hepatology Communications. 5(11). 1911–1926. 11 indexed citations

Gough, Albert, Alejandro Soto–Gutiérrez, Lawrence A. Vernetti, et al.. (2020). Human biomimetic liver microphysiology systems in drug development and precision medicine. Nature Reviews Gastroenterology & Hepatology. 18(4). 252–268. 85 indexed citations

Vosough, Massoud, Roberto Gramignoli, Ewa Ellis, et al.. (2019). Guide to the Assessment of Mature Liver Gene Expression in Stem Cell-Derived Hepatocytes. Stem Cells and Development. 28(14). 907–919. 46 indexed citations

l’Hortet, Alexandra Collin de, Kazuki Takeishi, Jorge Guzman‐Lepe, et al.. (2019). Generation of Human Fatty Livers Using Custom-Engineered Induced Pluripotent Stem Cells with Modifiable SIRT1 Metabolism. Cell Metabolism. 30(2). 385–401.e9. 73 indexed citations

Guzman‐Lepe, Jorge, Kazuki Takeishi, Toshimasa Nakao, et al.. (2016). SIRT1 Disruption in Human Fetal Hepatocytes Leads to Increased Accumulation of Glucose and Lipids. PLoS ONE. 11(2). e0149344–e0149344. 40 indexed citations

10.

Tafaleng, Edgar N., Souvik Chakraborty, Bing Han, et al.. (2015). Induced pluripotent stem cells model personalized variations in liver disease resulting from α1‐antitrypsin deficiency. Hepatology. 62(1). 147–157. 62 indexed citations

11.

Mann, David A., et al.. (2015). Future Economics of Liver Transplantation: A 20-Year Cost Modeling Forecast and the Prospect of Bioengineering Autologous Liver Grafts. PLoS ONE. 10(7). e0131764–e0131764. 65 indexed citations

12.

Duncan, Andrew W. & Alejandro Soto–Gutiérrez. (2013). Liver repopulation and regeneration. Current Opinion in Organ Transplantation. 18(2). 197–202. 23 indexed citations

13.

Soto–Gutiérrez, Alejandro, Jason A. Wertheim, Harald C. Ott, & Thomas W. Gilbert. (2012). Perspectives on whole-organ assembly: moving toward transplantation on demand. Journal of Clinical Investigation. 122(11). 3817–3823. 84 indexed citations

14.

Yagi, Hiroshi, Alejandro Soto–Gutiérrez, & Yuko Kitagawa. (2012). Whole-organ re-engineering: a regenerative medicine approach in digestive surgery for organ replacement. Surgery Today. 43(6). 587–594. 29 indexed citations

15.

Jaramillo, María, et al.. (2012). Analysis of alternative signaling pathways of endoderm induction of human embryonic stem cells identifies context specific differences. BMC Systems Biology. 6(1). 154–154. 17 indexed citations

16.

Soto–Gutiérrez, Alejandro, Li Zhang, Ken Fukumitsu, et al.. (2011). A Whole-Organ Regenerative Medicine Approach for Liver Replacement. Tissue Engineering Part C Methods. 17(6). 677–686. 232 indexed citations

17.

Navarro–Álvarez, Nalu, Alejandro Soto–Gutiérrez, & Naoya Kobayashi. (2010). Hepatic Stem Cells and Liver Development. Methods in molecular biology. 640. 181–236. 18 indexed citations

18.

Navarro–Álvarez, Nalu, Alejandro Soto–Gutiérrez, José Caballero-Corbalán, et al.. (2009). Intramuscular transplantation of engineered hepatic tissue constructs corrects acute and chronic liver failure in mice. Journal of Hepatology. 52(2). 211–219. 32 indexed citations

19.

Tolboom, Herman, Roos E. Pouw, Maria‐Louisa Izamis, et al.. (2009). Recovery of Warm Ischemic Rat Liver Grafts by Normothermic Extracorporeal Perfusion. Transplantation. 87(2). 170–177. 74 indexed citations

20.

Kobayashi, Naoya, Jorge David Rivas‐Carrillo, Alejandro Soto–Gutiérrez, et al.. (2005). Gene delivery to embryonic stem cells. Birth Defects Research Part C Embryo Today Reviews. 75(1). 10–18. 46 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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