Alejandro Soto–Gutiérrez

8.0k citations

105 papers · 5.8k indexed · 2 hit papers · h-index 39

Co-authors: Naoya Kobayashi Hiroshi Yagi Martin L. Yarmush Nalu Navarro–Álvarez Yuko Kitagawa Ronald G. Tompkins Ira J. Fox Arno W. Tilles
Topics: Liver physiology and pathology (44 papers)Pluripotent Stem Cells Research (30 papers)Organ Transplantation Techniques and Outcomes (27 papers)
Cited by: Hepatology Biomaterials Genetics
Journals: Journal of Clinical Investigation Nature MedicineSHILAP Revista de lepidopterología
Partner nations: United States Japan Sweden

In The Last Decade

Alejandro Soto–Gutiérrez

103 papers receiving 5.7k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Organ reengineering through development of a transplantable recellularized liver graft using decellularized liver matrix

2010 1.0k citations Alejandro Soto–Gutiérrez, Hiroshi Yagi et al. profile →
Mesenchymal Stem Cells: Mechanisms of Immunomodulation and Homing

2010 552 citations Hiroshi Yagi, Alejandro Soto–Gutiérrez et al. profile →

Peers

Countries citing papers authored by Alejandro Soto–Gutiérrez

Since Specialization

Citations

This map shows the geographic impact of Alejandro Soto–Gutiérrez's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Alejandro Soto–Gutiérrez with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Alejandro Soto–Gutiérrez more than expected).

Fields of papers citing papers by Alejandro Soto–Gutiérrez

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Alejandro Soto–Gutiérrez. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Alejandro Soto–Gutiérrez. The network helps show where Alejandro Soto–Gutiérrez may publish in the future.

Co-authorship network of co-authors of Alejandro Soto–Gutiérrez

This figure shows the co-authorship network connecting the top 25 collaborators of Alejandro Soto–Gutiérrez. A scholar is included among the top collaborators of Alejandro Soto–Gutiérrez based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Alejandro Soto–Gutiérrez. Alejandro Soto–Gutiérrez is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Comparison of wild-type and high-risk PNPLA3 variants in a human biomimetic liver microphysiology system for metabolic dysfunction-associated steatotic liver disease precision therapy 2024 ·Frontiers in Cell and Developmental Biology ·(unknown),(unknown),(unknown),(unknown),Richard DeBiasio,(unknown),(unknown),Rodrigo M. Florentino,(unknown),Jacquelyn A. Brown,Lawrence A. Vernetti,Mark E. Schurdak,Andrew M. Stern,Albert Gough,Jaideep Behari,Alejandro Soto–Gutiérrez,D. Lansing Taylor,Mark T. Miedel	7
2	Evaluation of Human Hepatocyte Drug Metabolism Carrying High-Risk or Protection-Associated Liver Disease Genetic Variants 2023 ·International Journal of Molecular Sciences ·(unknown),(unknown),(unknown),(unknown),(unknown),Zhiping Hu,Takeshi Kurihara,Edgar N. Tafaleng,Rodrigo M. Florentino,Zi Wang,Mengying Xia,Mark T. Miedel,D. Lansing Taylor,Jaideep Behari,Alina Ostrowska,Robert Constantine,Albert P. Li,Alejandro Soto–Gutiérrez	8
3	Long-read single-cell sequencing reveals expressions of hypermutation clusters of isoforms in human liver cancer cells 2023 ·eLife ·Silvia Liu,Yanping Yu,Bao‐Guo Ren,(unknown),Caroline Obert,M. Smith,Wenjia Wang,Alina Ostrowska,Alejandro Soto–Gutiérrez,Jianhua Luo	2
4	Transplantation of bioengineered liver capable of extended function in a preclinical liver failure model 2021 ·American Journal of Transplantation ·Hisanobu Higashi,Hiroshi Yagi,Kohei Kuroda,Kazuki Tajima,(unknown),(unknown),(unknown),(unknown),Kazumasa Fukuda,Kentaro Matsubara,Minoru Kitago,Masahiro Shinoda,Hideaki Obara,Shungo Adachi,(unknown),Tohru Natsume,Masatoshi Tomi,Alejandro Soto–Gutiérrez,Yuko Kitagawa	13
5	Hepatocyte Nuclear Factor 4 alpha 2 Messenger RNA Reprograms Liver‐Enriched Transcription Factors and Functional Proteins in End‐Stage Cirrhotic Human Hepatocytes 2021 ·Hepatology Communications ·Edgar N. Tafaleng,Amitava Mukherjee,Aaron Bell,(unknown),Jorge Guzman‐Lepe,Nils Haep,Rodrigo M. Florentino,(unknown),Carla Frau,Alina Ostrowska,Joshua R. Schultz,Paolo Martini,Alejandro Soto–Gutiérrez,Ira J. Fox	11
6	Human biomimetic liver microphysiology systems in drug development and precision medicine 2020 ·Nature Reviews Gastroenterology & Hepatology ·Albert Gough,Alejandro Soto–Gutiérrez,Lawrence A. Vernetti,Mo R. Ebrahimkhani,Andrew M. Stern,D. Lansing Taylor	85
7	Guide to the Assessment of Mature Liver Gene Expression in Stem Cell-Derived Hepatocytes 2019 ·Stem Cells and Development ·(unknown),(unknown),Massoud Vosough,(unknown),(unknown),Roberto Gramignoli,Ewa Ellis,Kristina Kannisto,Alexandra Collin de l’Hortet,Kazuki Takeishi,Alejandro Soto–Gutiérrez,Stephen C. Strom	46
8	Generation of Human Fatty Livers Using Custom-Engineered Induced Pluripotent Stem Cells with Modifiable SIRT1 Metabolism 2019 ·Cell Metabolism ·Alexandra Collin de l’Hortet,Kazuki Takeishi,Jorge Guzman‐Lepe,(unknown),Abhinav Achreja,Branimir Popovic,Yang Wang,Kan Handa,Anjali Mittal,Noah Meurs,Ziwen Zhu,Frank Weinberg,Michael Salomon,Ira J. Fox,Chu‐Xia Deng,Deepak Nagrath,Alejandro Soto–Gutiérrez	73
9	SIRT1 Disruption in Human Fetal Hepatocytes Leads to Increased Accumulation of Glucose and Lipids 2016 ·PLoS ONE ·(unknown),Jorge Guzman‐Lepe,Kazuki Takeishi,Toshimasa Nakao,Yang Wang,Fanying Meng,(unknown),Alexandra Collin de l’Hortet,Alejandro Soto–Gutiérrez	40
10	Induced pluripotent stem cells model personalized variations in liver disease resulting from α1‐antitrypsin deficiency 2015 ·Hepatology ·Edgar N. Tafaleng,Souvik Chakraborty,Bing Han,Pamela Hale,(unknown),Alejandro Soto–Gutiérrez,Carol Feghali‐Bostwick,Andrew A. Wilson,Darrell N. Kotton,Masaki Nagaya,Stephen C. Strom,Jayanta Roy‐Chowdhury,Donna B. Stolz,David H. Perlmutter,Ira J. Fox	62
11	Future Economics of Liver Transplantation: A 20-Year Cost Modeling Forecast and the Prospect of Bioengineering Autologous Liver Grafts 2015 ·PLoS ONE ·(unknown),David A. Mann,(unknown),Alejandro Soto–Gutiérrez	65
12	Liver repopulation and regeneration 2013 ·Current Opinion in Organ Transplantation ·Andrew W. Duncan,Alejandro Soto–Gutiérrez	23
13	Perspectives on whole-organ assembly: moving toward transplantation on demand 2012 ·Journal of Clinical Investigation ·Alejandro Soto–Gutiérrez,Jason A. Wertheim,Harald C. Ott,Thomas W. Gilbert	84
14	Whole-organ re-engineering: a regenerative medicine approach in digestive surgery for organ replacement 2012 ·Surgery Today ·Hiroshi Yagi,Alejandro Soto–Gutiérrez,Yuko Kitagawa	29
15	Analysis of alternative signaling pathways of endoderm induction of human embryonic stem cells identifies context specific differences 2012 ·BMC Systems Biology ·(unknown),María Jaramillo,(unknown),(unknown),Alejandro Soto–Gutiérrez,Ipsita Banerjee	17
16	A Whole-Organ Regenerative Medicine Approach for Liver Replacement 2011 ·Tissue Engineering Part C Methods ·Alejandro Soto–Gutiérrez,Li Zhang,(unknown),Ken Fukumitsu,Denver M. Faulk,Hongbin Jiang,Janet E. Reing,Roberto Gramignoli,Junji Komori,Mark A. Ross,Masaki Nagaya,Eric Lagasse,Donna B. Stolz,Stephen C. Strom,Ira J. Fox,Stephen F. Badylak	232
17	Hepatic Stem Cells and Liver Development 2010 ·Methods in molecular biology ·Nalu Navarro–Álvarez,Alejandro Soto–Gutiérrez,Naoya Kobayashi	18
18	Intramuscular transplantation of engineered hepatic tissue constructs corrects acute and chronic liver failure in mice 2009 ·Journal of Hepatology ·Nalu Navarro–Álvarez,Alejandro Soto–Gutiérrez,(unknown),José Caballero-Corbalán,(unknown),Satoru Kobayashi,Yoshitaka Kondo,Masaya Iwamuro,Kazuhide Yamamoto,Eisei Kondo,Noriaki Tanaka,Ira J. Fox,Naoya Kobayashi	32
19	Recovery of Warm Ischemic Rat Liver Grafts by Normothermic Extracorporeal Perfusion 2009 ·Transplantation ·Herman Tolboom,Roos E. Pouw,Maria‐Louisa Izamis,Jack M. Milwid,Nripen Sharma,Alejandro Soto–Gutiérrez,Yaakov Nahmias,Korkut Uygun,François Berthiaume,Martin L. Yarmush	74
20	Gene delivery to embryonic stem cells 2005 ·Birth Defects Research Part C Embryo Today Reviews ·Naoya Kobayashi,Jorge David Rivas‐Carrillo,Alejandro Soto–Gutiérrez,Takuya Fukazawa,Yong Chen,Nalu Navarro–Álvarez,Noriaki Tanaka	46

About Alejandro Soto–Gutiérrez

Alejandro Soto–Gutiérrez is a scholar working on Hepatology, Surgery and Biomaterials, having authored 105 papers that have together received 5.8k indexed citations. Recurring topics across this work include Liver physiology and pathology (44 papers), Pluripotent Stem Cells Research (30 papers) and Organ Transplantation Techniques and Outcomes (27 papers). The work is most often cited by research in Hepatology (1.9k citations), Biomaterials (1.4k citations) and Genetics (825 citations). Alejandro Soto–Gutiérrez has collaborated with scholars based in United States, Japan and Sweden. Frequent co-authors include Naoya Kobayashi, Hiroshi Yagi, Martin L. Yarmush, Nalu Navarro–Álvarez, Yuko Kitagawa, Ronald G. Tompkins, Ira J. Fox, Arno W. Tilles, Yaakov Nahmias and Biju Parekkadan. Their work appears in journals such as Journal of Clinical Investigation, Nature Medicine and SHILAP Revista de lepidopterología.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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