Joseph R. Klim

2.6k total citations · 1 hit paper
19 papers, 1.6k citations indexed

About

Joseph R. Klim is a scholar working on Molecular Biology, Neurology and Genetics. According to data from OpenAlex, Joseph R. Klim has authored 19 papers receiving a total of 1.6k indexed citations (citations by other indexed papers that have themselves been cited), including 14 papers in Molecular Biology, 9 papers in Neurology and 8 papers in Genetics. Recurrent topics in Joseph R. Klim's work include Amyotrophic Lateral Sclerosis Research (9 papers), Neurogenetic and Muscular Disorders Research (8 papers) and Pluripotent Stem Cells Research (6 papers). Joseph R. Klim is often cited by papers focused on Amyotrophic Lateral Sclerosis Research (9 papers), Neurogenetic and Muscular Disorders Research (8 papers) and Pluripotent Stem Cells Research (6 papers). Joseph R. Klim collaborates with scholars based in United States, Netherlands and United Kingdom. Joseph R. Klim's co-authors include Kevin Eggan, Laura L. Kiessling, Lingyin Li, Luis A. Williams, Paul J. Wrighton, Brandi N. Davis‐Dusenbery, Marian S. Piekarczyk, Irune Guerra San Juan, Francesco Limone and Ratmir Derda and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of the American Chemical Society and Neuron.

In The Last Decade

Joseph R. Klim

19 papers receiving 1.6k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

ALS-implicated protein TDP-43 sustains levels of STMN2, a mediator of motor neuron growth and repair

2019 345 citations Joseph R. Klim, Luis A. Williams et al. Nature Neuroscience profile →

Peers

Countries citing papers authored by Joseph R. Klim

Since Specialization

Citations

This map shows the geographic impact of Joseph R. Klim's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Joseph R. Klim with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Joseph R. Klim more than expected).

Fields of papers citing papers by Joseph R. Klim

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Joseph R. Klim. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Joseph R. Klim. The network helps show where Joseph R. Klim may publish in the future.

Co-authorship network of co-authors of Joseph R. Klim

This figure shows the co-authorship network connecting the top 25 collaborators of Joseph R. Klim. A scholar is included among the top collaborators of Joseph R. Klim based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Joseph R. Klim. Joseph R. Klim is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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19 of 19 papers shown

#	Work	Indexed citations
1	Single Acetylation-mimetic Mutation in TDP-43 Nuclear Localization Signal Disrupts Importin α1/β Signaling 2024 ·Journal of Molecular Biology ·Ying‐Hui Ko, Ravi K. Lokareddy, Steven G. Doll, (unknown), Amandeep Girdhar, (unknown), Joseph R. Klim, Noreen F. Rizvi, Rachel Meyers, Richard E. Gillilan, Lin Guo, Gino Cingolani	4
2	Downregulation of the silent potassium channel Kv8.1 increases motor neuron vulnerability in amyotrophic lateral sclerosis 2024 ·Brain Communications ·Xuan Huang, Seungkyu Lee, Kuchuan Chen, Riki Kawaguchi, Ole Wiskow, Sulagna Ghosh, (unknown), (unknown), (unknown), Joseph R. Klim, (unknown), (unknown), Kenneth J. Livak, Daniel H. Geschwind, Brian J. Wainger, Kevin Eggan, Bruce P. Bean, Clifford J. Woolf	3
3	Efficient generation of lower induced motor neurons by coupling Ngn2 expression with developmental cues 2023 ·Cell Reports ·Francesco Limone, Irune Guerra San Juan, Jana M. Mitchell, (unknown), (unknown), Daniel Meyer, Sulagna Ghosh, Alexander Benavides Couto, Joseph R. Klim, Brian Joseph, (unknown), Curtis J. Mello, James Nemesh, (unknown), Matthijs Verhage, Steven A. McCarroll, Olli Pietiläinen, Ralda Nehme, Kevin Eggan	17
4	Granulin loss of function in human mature brain organoids implicates astrocytes in TDP-43 pathology 2023 ·Stem Cell Reports ·Martina de Majo, Mark Koontz, Elise Marsan, Nir Salinas, Marina Ramsey, Yien–Ming Kuo, Kyounghee Seo, (unknown), Nina M. Dräger, Kun Leng, (unknown), Michael Kurnellas, Yuichiro Miyaoka, Joseph R. Klim, Martin Kampmann, Michael E. Ward, Eric J. Huang, Erik M. Ullian	19
5	Loss of mouse Stmn2 function causes motor neuropathy 2022 ·Neuron ·Irune Guerra San Juan, Leslie A. Nash, Kevin S. Smith, (unknown), (unknown), Joseph R. Klim, Francesco Limone, (unknown), Alexander Benavides Couto, Greta Pintacuda, Brian Joseph, (unknown), (unknown), (unknown), (unknown), Amie L. Holmes, Aaron Burberry, Matthijs Verhage, Kevin Eggan	40
6	Pluripotent stem cell strategies for rebuilding the human brain 2022 ·Frontiers in Aging Neuroscience ·Francesco Limone, Joseph R. Klim, Daniel A. Mordes	10
7	Connecting TDP-43 Pathology with Neuropathy 2021 ·Trends in Neurosciences ·Joseph R. Klim, Greta Pintacuda, Leslie A. Nash, Irune Guerra San Juan, Kevin Eggan	44
8	Antisense oligonucleotide therapies for Amyotrophic Lateral Sclerosis: Existing and emerging targets 2019 ·The International Journal of Biochemistry & Cell Biology ·Joseph R. Klim, Caroline Vance, Emma L. Scotter	19
9	ALS-implicated protein TDP-43 sustains levels of STMN2, a mediator of motor neuron growth and repair breakdown → 2019 ·Nature Neuroscience ·Joseph R. Klim, Luis A. Williams, Francesco Limone, Irune Guerra San Juan, Brandi N. Davis‐Dusenbery, Daniel A. Mordes, Aaron Burberry, Michael J. Steinbaugh, Kanchana K. Gamage, Rory Kirchner, Rob Moccia, Seth H. Cassel, Kuchuan Chen, Brian J. Wainger, Clifford J. Woolf, Kevin Eggan	345
10	Dipeptide repeat proteins activate a heat shock response found in C9ORF72-ALS/FTLD patients 2018 ·Acta Neuropathologica Communications ·Daniel A. Mordes, Mercedes Prudencio, Lindsey D. Goodman, Joseph R. Klim, Rob Moccia, Francesco Limone, Olli Pietiläinen, Kaitavjeet Chowdhary, Dennis W. Dickson, Rosa Rademakers, Nancy M. Bonini, Leonard Petrucelli, Kevin Eggan	20
11	Reactive Astrocytes Promote ALS-like Degeneration and Intracellular Protein Aggregation in Human Motor Neurons by Disrupting Autophagy through TGF-β1 2017 ·Stem Cell Reports ·Pratibha Tripathi, Natalia Rodríguez‐Muela, Joseph R. Klim, (unknown), (unknown), Jackson Sandoe, Claúdia Lopes, (unknown), Luis A. Williams, (unknown), Lee L. Rubin, Kevin Eggan, Qiao Zhou	99
12	Modeling ALS with motor neurons derived from human induced pluripotent stem cells 2016 ·Nature Neuroscience ·Samuel Sances, Lucie Bruijn, Siddharthan Chandran, Kevin Eggan, Ritchie Ho, Joseph R. Klim, Matthew R. Livesey, Emily R. Lowry, Jeffrey D. Macklis, David J. Rushton, Cameron Sadegh, Dhruv Sareen, Hynek Wichterle, Su‐Chun Zhang, Clive N. Svendsen	201
13	Genetic Ablation of AXL Does Not Protect Human Neural Progenitor Cells and Cerebral Organoids from Zika Virus Infection 2016 ·Cell stem cell ·Michael F. Wells, Max R. Salick, Ole Wiskow, Daniel Ho, Kathleen A. Worringer, Robert J. Ihry, Sravya Kommineni, Bilada Bilican, Joseph R. Klim, (unknown), Liam T. Kane, Chaoyang Ye, Ajamete Kaykas, Kevin Eggan	211
14	How to make spinal motor neurons 2014 ·Development ·Brandi N. Davis‐Dusenbery, Luis A. Williams, Joseph R. Klim, Kevin Eggan	111
15	Signals from the surface modulate differentiation of human pluripotent stem cells through glycosaminoglycans and integrins 2014 ·Proceedings of the National Academy of Sciences ·Paul J. Wrighton, Joseph R. Klim, (unknown), Chad H. Koonce, Timothy J. Kamp, Laura L. Kiessling	52
16	Small-Molecule-Modified Surfaces Engage Cells through the α_vβ₃ Integrin 2011 ·ACS Chemical Biology ·Joseph R. Klim, Anthony J. Fowler, Adam H. Courtney, Paul J. Wrighton, (unknown), (unknown), Laura L. Kiessling	18
17	Spatial control of cell fate using synthetic surfaces to potentiate TGF-β signaling 2011 ·Proceedings of the National Academy of Sciences ·Lingyin Li, Joseph R. Klim, Ratmir Derda, Adam H. Courtney, Laura L. Kiessling	46
18	High-Throughput Discovery of Synthetic Surfaces That Support Proliferation of Pluripotent Cells 2010 ·Journal of the American Chemical Society ·Ratmir Derda, Samira Musah, Brendan P. Orner, Joseph R. Klim, Lingyin Li, Laura L. Kiessling	104
19	A defined glycosaminoglycan-binding substratum for human pluripotent stem cells 2010 ·Nature Methods ·Joseph R. Klim, Lingyin Li, Paul J. Wrighton, Marian S. Piekarczyk, Laura L. Kiessling	218

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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