Jonathan C. Kagan

22.4k citations

121 papers · 16.0k indexed · 15 hit papers · h-index 54

Impact in

Immunology top 0.05%
- Immune Response and Inflammation
- interferon and immune responses
- Immune Cell Function and Interaction
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Immune cells in cancer
- Immunotherapy and Immune Responses
Endocrinology top 0.2%
- Legionella and Acanthamoeba research

Papers in

Immunology 101
- Immune Response and Inflammation 59
- interferon and immune responses 51
- Immune Cell Function and Interaction 19
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms 17
Endocrinology 12

Co-authors: Katherine A. Fitzgerald Ruslan Medzhitov Gregory M. Barton Ivan Zanoni Craig R. Roy Yunhao Tan Charles L. Evavold Hao Wu
Journals: Cell (12 papers)Immunity (9 papers)Science Immunology (6 papers)Trends in Immunology (5 papers)Science (4 papers)
Partner nations: United States Italy United Kingdom

In The Last Decade

Jonathan C. Kagan

116 papers receiving 15.8k citations

Hit Papers

15 papers align trajectories log scale

Molecular mechanisms of gasdermin D pore-forming activity 2023 · 148 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2023 Nature Immunology
2023 Cell Reports
2023 Immunity
2021 Cell
2020 Science
2020 Cell
2017 Immunity
2016 Science
2015 Annual Review of Immunology
2011 Cell
2010 Cell
2009 Nature reviews. Immunology
2008 Nature Immunology
2006 Cell
2005 Nature Immunology

Peers

Countries citing papers authored by Jonathan C. Kagan

Since Specialization

Citations

This map shows the geographic impact of Jonathan C. Kagan's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jonathan C. Kagan with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jonathan C. Kagan more than expected).

Fields of papers citing papers by Jonathan C. Kagan

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jonathan C. Kagan. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jonathan C. Kagan. The network helps show where Jonathan C. Kagan may publish in the future.

Co-authors

The 25 scholars most cited alongside Jonathan C. Kagan, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Jonathan C. Kagan Line = papers co-authored together Jonathan C. Kagan links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	MAVS oligomerization drives a faster and more efficient antiviral signaling activation at peroxisomes compared to mitochondria FEBS Journal ·Silvia Stammen, Mario Z. Rosenberg, Ayaka Shimodouzono, Jonathan C. Kagan, Daniela Ribeiro	2025	0
2	Towards a molecular and structural definition of cell death Nature Structural & Molecular Biology ·Eli Arama, Katia Cosentino, Peter E. Czabotar, Boyi Gan, Elizabeth L. Hartland, Xuejun Jiang, Jonathan C. Kagan, Shigekazu Nagata, Kate Schroder, M. B. Popova, Fabian Landaverde S., Junying Yuan	2025	0
3	Molecular definition of the endogenous Toll-like receptor signalling pathways Nature ·Daniel Fisch, Emmanuel Liégeon, He Sun, Yubo Guo, Yunhao Tan, Steven P. Gygi, Darren E. Higgins, Jonathan C. Kagan	2024	41
4	Structural transitions enable interleukin-18 maturation and signaling Immunity ·Ying Dong, L'. Janků, Pascal Devant, Zhuoyi Liang, Thomas Pucci, Julian Mintseris, James M. Aramini, Gang Du, Stephen P. Gygi, Jonathan C. Kagan, (unknown), Hao Wu	2024	10
5	Structural insights into cytokine cleavage by inflammatory caspase-4 Nature ·Pascal Devant, Ying Dong, Julian Mintseris, Yubo Guo, Steven P. Gygi, Hao Wu, Jonathan C. Kagan	2023	44
6	Gasdermin D pore-forming activity is redox-sensitive Cell Reports ·Pascal Devant, Carlos Fredique Méndez, Elsy M. Ngwa, Haopeng Xiao, Edward T. Chouchani, Jay R. Thiagarajah, Iva Hafner‐Bratkovič, Charles L. Evavold, Jonathan C. Kagan Hit paper breakdown →	2023	85
7	Human Cytomegalovirus vMIA Inhibits MAVS Oligomerization at Peroxisomes in an MFF-Dependent Manner Frontiers in Cell and Developmental Biology ·Ana Ferreira, А К Туркумбаев, Ana C. Magalhães, L. Malcolm, Ayaka Shimodouzono, Jonathan C. Kagan, Daniela Ribeiro	2022	15
8	Deep-sea microbes as tools to refine the rules of innate immune pattern recognition Science Immunology ·Anna E. Gauthier, Courtney E. Chandler, Valentina Poli, Samantha Ellingson, Марина Колеснікова, Richard D. Smith, Kevin S. Bonham, Erik E. Cordes, Timothy M. Shank, Ivan Zanoni, David R. Goodlett, Steven J. Biller, Robert K. Ernst, Randi Rotjan, Jonathan C. Kagan	2021	27
9	TBK1 and IKKε act like an OFF switch to limit NLRP3 inflammasome pathway activation Proceedings of the National Academy of Sciences ·А.Б. Шикалов, C Pniewska, Анатолий Дмитриевич Качан, Eirini Pantazi, Sara Danielli, Benjamin Demarco, Michael Ohlmeyer, Michelle Sue Jann Lee, Cevayir Coban, Jonathan C. Kagan, Elena Di Daniel, Jelena S. Bezbradica	2021	28
10	Heterologous Expression and Assembly of Human TLR Signaling Components in Saccharomyces cerevisiae Biomolecules ·Julia María Coronas-Serna, V.A. Proshkina, Jonathan C. Kagan, Marı́a Molina, Vı́ctor J. Cid	2021	4
11	HDAC6 mediates an aggresome-like mechanism for NLRP3 and pyrin inflammasome activation Science ·Venkat Giri Magupalli, Roberto Negro, Yuzi Tian, Arthur V. Hauenstein, Giuseppe Di Caprio, Wesley Skillern, Qiufang Deng, Pontus Ørning, Hasan B. Alam, Zoltan Maliga, Humayun Sharif, Jun Hu, Charles L. Evavold, Jonathan C. Kagan, Florian I. Schmidt, Katherine A. Fitzgerald, Tomas Kirchhausen, Yongqing Li, Hao Wu Hit paper breakdown →	2020	286
12	Patterns, dynamics and consequences of microplastic ingestion by the temperate coral, Astrangia poculata Proceedings of the Royal Society B Biological Sciences ·Randi Rotjan, Koty Sharp, Anna E. Gauthier, Ishita Ramdasi, Matheus Eduardo Dos Santos, Jessica Carilli, Jonathan C. Kagan, Juanita Urban-Rich	2019	116
13	An endogenous caspase-11 ligand elicits interleukin-1 release from living dendritic cells Science ·Ivan Zanoni, Yunhao Tan, Marco Di Gioia, Achille Broggi, Jianbin Ruan, Jianjin Shi, Carlos Donado, Feng Shao, Hao Wu, James R. Springstead, Jonathan C. Kagan Hit paper breakdown →	2016	442
14	Microbe‐inducible trafficking pathways that control Toll‐like receptor signaling Traffic ·Yunhao Tan, Jonathan C. Kagan	2016	22
15	A Bicistronic MAVS Transcript Highlights a Class of Truncated Variants in Antiviral Immunity Cell ·Sky W. Brubaker, Anna E. Gauthier, Eric W. Mills, Nicholas T. Ingolia, Jonathan C. Kagan	2014	117
16	Peroxisomes Are Signaling Platforms for Antiviral Innate Immunity Cell ·Evelyn Dixit, Steeve Boulant, Yijing Zhang, Amy S.Y. Lee, Charlotte Odendall, Bennett O. V. Shum, Nir Hacohen, Zhijian J. Chen, Sean P. J. Whelan, Marc Fransen, Max L. Nibert, Giulio Superti‐Furga, Jonathan C. Kagan Hit paper breakdown →	2010	649
17	Microtubule motors control membrane dynamics of Salmonella-containing vacuoles Journal of Cell Science ·Julie Guignot, Emmanuelle Caron, Carmen R. Beuzón, Cecilia Bucci, Jonathan C. Kagan, Craig R. Roy, David W. Holden	2004	102
18	Legionella Subvert the Functions of Rab1 and Sec22b to Create a Replicative Organelle The Journal of Experimental Medicine ·Jonathan C. Kagan, Mary‐Pat Stein, Marc Pypaert, Craig R. Roy	2004	236
19	A C-terminal translocation signal required for Dot/Icm-dependent delivery of the Legionella RalF protein to host cells Proceedings of the National Academy of Sciences ·Hiroki Nagai, Eric D. Cambronne, Jonathan C. Kagan, Juan Carlos Amor, Richard Kahn, Craig R. Roy	2004	232
20	A Bacterial Guanine Nucleotide Exchange Factor Activates ARF on Legionella Phagosomes Science ·Hiroki Nagai, Jonathan C. Kagan, Xinjun Zhu, Richard Kahn, Craig R. Roy	2002	450

About Jonathan C. Kagan

Jonathan C. Kagan is a scholar working on Immunology, Endocrinology, Microbiology, Molecular Biology and Physiology, having authored 121 papers that have together received 16.0k indexed citations. Recurring topics across this work include Immune Response and Inflammation (59 papers), interferon and immune responses (51 papers), Inflammasome and immune disorders (36 papers), Immune Cell Function and Interaction (19 papers), Neutrophil, Myeloperoxidase and Oxidative Mechanisms (17 papers), Heme Oxygenase-1 and Carbon Monoxide (9 papers), Influenza Virus Research Studies (8 papers) and Antimicrobial Peptides and Activities (7 papers). The work is most often cited by research in Immunology (9.5k citations), Endocrinology (1.5k citations), Molecular Biology (7.5k citations), Microbiology (584 citations) and Infectious Diseases (1.5k citations). Jonathan C. Kagan has collaborated with scholars based in United States, Italy and United Kingdom. Frequent co-authors include Katherine A. Fitzgerald, Ruslan Medzhitov, Gregory M. Barton, Ivan Zanoni, Craig R. Roy, Yunhao Tan, Charles L. Evavold, Hao Wu, Kevin S. Bonham and Sky W. Brubaker. Their work appears in journals such as Cell, Immunity, Science Immunology, Trends in Immunology and Science.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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