John Bertin

32.0k total citations · 11 hit papers
127 papers, 21.4k citations indexed

About

John Bertin is a scholar working on Molecular Biology, Immunology and Cancer Research. According to data from OpenAlex, John Bertin has authored 127 papers receiving a total of 21.4k indexed citations (citations by other indexed papers that have themselves been cited), including 80 papers in Molecular Biology, 65 papers in Immunology and 25 papers in Cancer Research. Recurrent topics in John Bertin's work include Cell death mechanisms and regulation (44 papers), Inflammasome and immune disorders (32 papers) and Immune Response and Inflammation (31 papers). John Bertin is often cited by papers focused on Cell death mechanisms and regulation (44 papers), Inflammasome and immune disorders (32 papers) and Immune Response and Inflammation (31 papers). John Bertin collaborates with scholars based in United States, Germany and France. John Bertin's co-authors include Peter J. Gough, Peter S. DiStefano, Anthony J. Coyle, Ethan Grant, Richard A. Flavell, Gabriel Núñez, Peter Vandenabeele, Thirumala‐Devi Kanneganti, Dana J. Philpott and Stephen E. Girardin and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

John Bertin

127 papers receiving 21.1k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

NLRP6 Inflammasome Regulates Colonic Microbial Ecology and Risk for Colitis

2011 1.6k citations John Bertin et al. profile →
Nod1 Detects a Unique Muropeptide from Gram-Negative Bacterial Peptidoglycan

2003 1.2k citations Stephen E. Girardin, Ivo G. Boneca et al. Science profile →
Nod1 responds to peptidoglycan delivered by the Helicobacter pylori cag pathogenicity island

2004 971 citations Jérôme Viala, Ivo G. Boneca et al. Nature Immunology profile →
Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1β in salmonella-infected macrophages

2006 949 citations Luigi Franchi, Amal O. Amer et al. Nature Immunology profile →
Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3

2006 935 citations Thirumala‐Devi Kanneganti, Nesrin Özören et al. profile →
Pathogen blockade of TAK1 triggers caspase-8–dependent cleavage of gasdermin D and cell death

2018 800 citations Pontus Ørning, Dan Weng et al. Science profile →
Critical Role for NALP3/CIAS1/Cryopyrin in Innate and Adaptive Immunity through Its Regulation of Caspase-1

2006 799 citations Ethan Grant, John Bertin et al. profile →
Toll-like Receptor 3-mediated Necrosis via TRIF, RIP3, and MLKL

2013 747 citations William J. Kaiser, Chunzi Huang et al. Journal of Biological Chemistry profile →
MLKL Compromises Plasma Membrane Integrity by Binding to Phosphatidylinositol Phosphates

2014 663 citations Yves Dondelinger, Clark A. Sehon et al. profile →
CARD4/Nod1 mediates NF‐κB and JNK activation by invasive Shigella flexneri

2001 503 citations Stephen E. Girardin, Régis Tournebize et al. EMBO Reports profile →
Neuronal Death After Hemorrhagic Stroke In Vitro and In Vivo Shares Features of Ferroptosis and Necroptosis

2017 428 citations Peter J. Gough, John Bertin et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
John Bertin United States	67	14.1k	11.0k	2.7k	2.3k	1.9k	127	21.4k
Jenny P.‐Y. Ting United States	76	15.1k 1.1×	13.4k 1.2×	3.6k 1.3×	1.7k 0.7×	2.1k 1.1×	215	25.6k
Fabio Martinon Switzerland	55	18.5k 1.3×	13.0k 1.2×	3.6k 1.3×	2.0k 0.9×	2.9k 1.5×	98	27.9k
Feng Shao China	67	23.6k 1.7×	10.6k 1.0×	3.2k 1.2×	1.7k 0.8×	2.0k 1.0×	167	31.7k
Kate Schroder Australia	58	14.4k 1.0×	9.8k 0.9×	3.6k 1.3×	1.1k 0.5×	2.0k 1.0×	143	23.7k
Mohamed Lamkanfi Belgium	69	16.7k 1.2×	10.2k 0.9×	3.1k 1.1×	1.1k 0.5×	2.2k 1.1×	108	22.5k
Kensuke Miyake Japan	78	7.2k 0.5×	15.8k 1.4×	4.0k 1.5×	2.5k 1.1×	1.2k 0.6×	214	23.8k
Paola Ricciardi‐Castagnoli Italy	65	9.7k 0.7×	17.7k 1.6×	2.8k 1.0×	2.9k 1.3×	952 0.5×	179	27.2k
Nobuhiko Kayagaki Japan	57	11.5k 0.8×	9.2k 0.8×	2.0k 0.7×	2.1k 0.9×	1.2k 0.6×	98	17.4k
Gunther Hartmann Germany	76	10.0k 0.7×	16.9k 1.5×	3.3k 1.2×	2.0k 0.9×	895 0.5×	251	25.1k
Martin Krönke Germany	73	10.3k 0.7×	8.1k 0.7×	2.2k 0.8×	2.7k 1.2×	889 0.5×	232	20.5k

Countries citing papers authored by John Bertin

Since Specialization

Citations

This map shows the geographic impact of John Bertin's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by John Bertin with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites John Bertin more than expected).

Fields of papers citing papers by John Bertin

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by John Bertin. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by John Bertin. The network helps show where John Bertin may publish in the future.

Co-authorship network of co-authors of John Bertin

This figure shows the co-authorship network connecting the top 25 collaborators of John Bertin. A scholar is included among the top collaborators of John Bertin based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with John Bertin. John Bertin is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Ørning, Pontus, Roland Elling, Michelle A. Kelliher, et al.. (2025). Raver1 links Ripk1 RNA splicing to caspase-8-mediated pyroptotic cell death, inflammation, and pathogen resistance. Proceedings of the National Academy of Sciences. 122(7). e2420802122–e2420802122. 2 indexed citations

Humphries, Fiachra, Liraz Shmuel-Galia, Zhaozhao Jiang, et al.. (2021). A diamidobenzimidazole STING agonist protects against SARS-CoV-2 infection. Science Immunology. 6(59). 115 indexed citations

Ouyang, Yulin, Li Wen, J. A. Armstrong, et al.. (2021). Protective Effects of Necrostatin-1 in Acute Pancreatitis: Partial Involvement of Receptor Interacting Protein Kinase 1. Cells. 10(5). 1035–1035. 16 indexed citations

Simpson, Jennifer, Zhixuan Loh, Md Ashik Ullah, et al.. (2020). Respiratory Syncytial Virus Infection Promotes Necroptosis and HMGB1 Release by Airway Epithelial Cells. American Journal of Respiratory and Critical Care Medicine. 201(11). 1358–1371. 89 indexed citations

Alfano, Danielle N., Linda R. Klei, Peter J. Gough, et al.. (2020). MALT1 Protease Plays a Dual Role in the Allergic Response by Acting in Both Mast Cells and Endothelial Cells. The Journal of Immunology. 204(9). 2337–2348. 12 indexed citations

Ørning, Pontus, Dan Weng, Kristian K. Starheim, et al.. (2018). Pathogen blockade of TAK1 triggers caspase-8–dependent cleavage of gasdermin D and cell death. Science. 362(6418). 1064–1069. 800 indexed citations breakdown →

Garcia‐Carbonell, Ricard, Jerry Wong, Ju Youn Kim, et al.. (2018). Elevated A20 promotes TNF-induced and RIPK1-dependent intestinal epithelial cell death. Proceedings of the National Academy of Sciences. 115(39). E9192–E9200. 75 indexed citations

Peterson, Lance W., Naomi H. Philip, Alexandra DeLaney, et al.. (2017). RIPK1-dependent apoptosis bypasses pathogen blockade of innate signaling to promote immune defense. The Journal of Experimental Medicine. 214(11). 3171–3182. 94 indexed citations

Hänggi, Kay, Aı̈da Valls, Rosario Yerbes, et al.. (2017). RIPK1/RIPK3 promotes vascular permeability to allow tumor cell extravasation independent of its necroptotic function. Cell Death and Disease. 8(2). e2588–e2588. 62 indexed citations

10.

Yu, Jong W., Sandy Hoffman, Allison M. Beal, et al.. (2015). MALT1 Protease Activity Is Required for Innate and Adaptive Immune Responses. PLoS ONE. 10(5). e0127083–e0127083. 66 indexed citations

11.

Moriwaki, Kenta, John Bertin, Peter J. Gough, & Francis Ka-Ming Chan. (2015). A RIPK3–Caspase 8 Complex Mediates Atypical Pro–IL-1β Processing. The Journal of Immunology. 194(4). 1938–1944. 142 indexed citations

12.

Kaiser, William J., Lisa P. Daley‐Bauer, Roshan J. Thapa, et al.. (2014). RIP1 suppresses innate immune necrotic as well as apoptotic cell death during mammalian parturition. Proceedings of the National Academy of Sciences. 111(21). 7753–7758. 233 indexed citations

13.

Gatheral, Timothy, Daniel M. Reed, Laura Moreno, et al.. (2012). A Key Role for the Endothelium in NOD1 Mediated Vascular Inflammation: Comparison to TLR4 Responses. PLoS ONE. 7(8). e42386–e42386. 37 indexed citations

14.

Chen, Grace, Maochang Liu, Fuyuan Wang, John Bertin, & Gabriel Núñez. (2011). A Functional Role for Nlrp6 in Intestinal Inflammation and Tumorigenesis. The Journal of Immunology. 186(12). 7187–7194. 358 indexed citations

15.

Yamasaki, Kenshi, Jun Muto, Kristen R. Taylor, et al.. (2009). NLRP3/Cryopyrin Is Necessary for Interleukin-1β (IL-1β) Release in Response to Hyaluronan, an Endogenous Trigger of Inflammation in Response to Injury. Journal of Biological Chemistry. 284(19). 12762–12771. 225 indexed citations

16.

Kirshner, Jessica R., Suqin He, Jane Kepros, et al.. (2008). Elesclomol induces cancer cell apoptosis through oxidative stress. Molecular Cancer Therapeutics. 7(8). 2319–2327. 275 indexed citations

17.

Foley, Kevin P., John Bertin, Amy Hutchings, et al.. (2007). The oxidative stress inducer STA-4783 enhances the in vivo efficacy of multiple anti-cancer therapies in mouse tumor models. Molecular Cancer Therapeutics. 6. 4 indexed citations

18.

Franchi, Luigi, Amal O. Amer, Mathilde Body–Malapel, et al.. (2006). Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1β in salmonella-infected macrophages. Nature Immunology. 7(6). 576–582. 949 indexed citations breakdown →

19.

Girardin, Stephen E., Ivo G. Boneca, Letícia A. M. Carneiro, et al.. (2003). Nod1 Detects a Unique Muropeptide from Gram-Negative Bacterial Peptidoglycan. Science. 300(5625). 1584–1587. 1220 indexed citations breakdown →

20.

Girardin, Stephen E., Régis Tournebize, Maria Mavris, et al.. (2001). CARD4/Nod1 mediates NF‐κB and JNK activation by invasive Shigella flexneri. EMBO Reports. 2(8). 736–742. 503 indexed citations breakdown →

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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