Darren E. Higgins

6.9k total citations · 1 hit paper
59 papers, 5.3k citations indexed

About

Darren E. Higgins is a scholar working on Biotechnology, Immunology and Molecular Biology. According to data from OpenAlex, Darren E. Higgins has authored 59 papers receiving a total of 5.3k indexed citations (citations by other indexed papers that have themselves been cited), including 34 papers in Biotechnology, 21 papers in Immunology and 16 papers in Molecular Biology. Recurrent topics in Darren E. Higgins's work include Listeria monocytogenes in Food Safety (30 papers), Microbial Inactivation Methods (16 papers) and Vibrio bacteria research studies (12 papers). Darren E. Higgins is often cited by papers focused on Listeria monocytogenes in Food Safety (30 papers), Microbial Inactivation Methods (16 papers) and Vibrio bacteria research studies (12 papers). Darren E. Higgins collaborates with scholars based in United States, Canada and Cuba. Darren E. Higgins's co-authors include John H. Brumell, Katherine P. Lemon, Roberto Kolter, Aimee Shen, Angelika Gründling, Laura S. Burrack, Herbert Tilg, Ann–Hwee Lee, Jonathan N. Glickman and Arthur Kaser and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Darren E. Higgins

59 papers receiving 5.2k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

XBP1 Links ER Stress to Intestinal Inflammation and Confers Genetic Risk for Human Inflammatory Bowel Disease

2008 1.1k citations Darren E. Higgins et al. profile →

Peers

Countries citing papers authored by Darren E. Higgins

Since Specialization

Citations

This map shows the geographic impact of Darren E. Higgins's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Darren E. Higgins with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Darren E. Higgins more than expected).

Fields of papers citing papers by Darren E. Higgins

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Darren E. Higgins. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Darren E. Higgins. The network helps show where Darren E. Higgins may publish in the future.

Co-authorship network of co-authors of Darren E. Higgins

This figure shows the co-authorship network connecting the top 25 collaborators of Darren E. Higgins. A scholar is included among the top collaborators of Darren E. Higgins based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Darren E. Higgins. Darren E. Higgins is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Molecular definition of the endogenous Toll-like receptor signalling pathways 2024 ·Nature ·Daniel Fisch, (unknown), He Sun, (unknown), Yunhao Tan, Steven P. Gygi, Darren E. Higgins, Jonathan C. Kagan	41
2	Sticholysins, pore-forming proteins from a marine anemone can induce maturation of dendritic cells through a TLR4 dependent-pathway 2021 ·Molecular Immunology ·(unknown), (unknown), (unknown), Catarina V. Nogueira, (unknown), (unknown), (unknown), Audry Fernández, Circe Mesa, Fabiola Pazos, Carlos Álvarez, (unknown), Michael N. Starnbach, Darren E. Higgins, Luis E. Fernández, Ieda Maria Longo‐Maugéri, María E. Lanio	5
3	Cutting Edge: NOX2 NADPH Oxidase Controls Infection by an Intracellular Bacterial Pathogen through Limiting the Type 1 IFN Response 2020 ·The Journal of Immunology ·(unknown), Taoyingnan Li, (unknown), (unknown), Aleixo M. Muise, Darren E. Higgins, John H. Brumell	5
4	Invasion of the Brain by Listeria monocytogenes Is Mediated by InlF and Host Cell Vimentin 2018 ·mBio ·Pallab Ghosh, (unknown), Dustin A. Ammendolia, Nirit Mor‐Vaknin, Mary O’Riordan, John H. Brumell, David M. Markovitz, Darren E. Higgins	79
5	Strain-Specific Interactions of Listeria monocytogenes with the Autophagy System in Host Cells 2015 ·PLoS ONE ·Marija Cemma, Grace Y. Lam, Martina Stöckli, Darren E. Higgins, John H. Brumell	11
6	Listeria monocytogenes exploits efferocytosis to promote cell-to-cell spread 2014 ·Nature ·(unknown), Ramzi Fattouh, Jorik M. van Rijn, Veronica Canadien, Suzanne E. Osborne, Aleixo M. Muise, Vijay K. Kuchroo, Darren E. Higgins, John H. Brumell	115
7	Host and bacterial factors that regulate LC3 recruitment to Listeria monocytogenes during the early stages of macrophage infection 2013 ·Autophagy ·Grace Y. Lam, Marija Cemma, Aleixo M. Muise, Darren E. Higgins, John H. Brumell	98
8	Listeriolysin O Suppresses Phospholipase C-Mediated Activation of the Microbicidal NADPH Oxidase to Promote Listeria monocytogenes Infection 2011 ·Cell Host & Microbe ·Grace Y. Lam, Ramzi Fattouh, Aleixo M. Muise, Sergio Grinstein, Darren E. Higgins, John H. Brumell	60
9	TH17-Based Vaccine Design for Prevention of Streptococcus pneumoniae Colonization 2011 ·Cell Host & Microbe ·Kristin Moffitt, Todd M. Gierahn, Ying‐Jie Lu, Paulo Gouveia, Mark R. Alderson, Jessica B. Flechtner, Darren E. Higgins, Richard Malley	152
10	Stimulation of Enhanced CD8 T Cell Responses Following Immunization with a Hyper-Antigen Secreting Intracytosolic Bacterial Pathogen 2008 ·The Journal of Immunology ·Megan J. Smithey, (unknown), Nancy E. Freitag, Darren E. Higgins, H. G. Archie Bouwer	7
11	Inhibition of ROCK activity allows InlF‐mediated invasion and increased virulence ofListeria monocytogenes 2008 ·Molecular Microbiology ·Marieluise Kirchner, Darren E. Higgins	34
12	Listeria monocytogenes evades killing by autophagy during colonization of host cells 2007 ·HAL (Le Centre pour la Communication Scientifique Directe) ·Cheryl L. Birmingham, Veronica Canadien, Edith Gouin, Erin B. Troy, Tamotsu Yoshimori, Pascale Cossart, Darren E. Higgins, John H. Brumell	9
13	A bifunctional O-GlcNAc transferase governs flagellar motility through anti-repression 2006 ·Genes & Development ·Aimee Shen, Heather D. Kamp, Angelika Gründling, Darren E. Higgins	94
14	The MogR Transcriptional Repressor Regulates Nonhierarchal Expression of Flagellar Motility Genes and Virulence in Listeria monocytogenes 2006 ·PLoS Pathogens ·Aimee Shen, Darren E. Higgins	90
15	Genome-Wide RNAi Screen for Host Factors Required for Intracellular Bacterial Infection 2005 ·Science ·Hervé Agaisse, Laura S. Burrack, Jennifer A. Philips, Eric J. Rubin, Norbert Perrimon, Darren E. Higgins	238
16	Listeria monocytogenes regulates flagellar motility gene expression through MogR, a transcriptional repressor required for virulence 2004 ·Proceedings of the National Academy of Sciences ·Angelika Gründling, Laura S. Burrack, H. G. Archie Bouwer, Darren E. Higgins	177
17	Listeria monocytogenes as a Vaccine Vector: Virulence Attenuation or Existing Antivector Immunity Does Not Diminish Therapeutic Efficacy 2004 ·The Journal of Immunology ·(unknown), Kevin W. Bruhn, Hao Shen, Ronald A. Barry, Thomas W. Dubensky, Dirk G. Brockstedt, David J. Hinrichs, Darren E. Higgins, (unknown), Martin Giedlin, H. G. Archie Bouwer	74
18	The Host Resistance Locus sst1 Controls Innate Immunity to Listeria monocytogenes Infection in Immunodeficient Mice 2004 ·The Journal of Immunology ·Victor Boyartchuk, Mauricio Rojas, Bo‐Shiun Yan, Ousman Jobe, (unknown), David M. Dorfman, Darren E. Higgins, William F. Dietrich, Igor Kramnik	29
19	Escherichia coli Expressing Recombinant Antigen and Listeriolysin O Stimulate Class I-Restricted CD8+ T Cells following Uptake by Human APC 2004 ·The Journal of Immunology ·Paul Q. Hu, (unknown), (unknown), (unknown), Darren E. Higgins, Simon C. Watkins, Russell D. Salter	35
20	Inducible Control of Virulence Gene Expression in Listeria monocytogenes : Temporal Requirement of Listeriolysin O during Intracellular Infection 2002 ·Journal of Bacteriology ·Christina E. Dancz, (unknown), Daniel A. Portnoy, Darren E. Higgins	49

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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