John R. Ussher

12.0k total citations · 3 hit papers
119 papers, 9.0k citations indexed

About

John R. Ussher is a scholar working on Molecular Biology, Cardiology and Cardiovascular Medicine and Physiology. According to data from OpenAlex, John R. Ussher has authored 119 papers receiving a total of 9.0k indexed citations (citations by other indexed papers that have themselves been cited), including 57 papers in Molecular Biology, 46 papers in Cardiology and Cardiovascular Medicine and 46 papers in Physiology. Recurrent topics in John R. Ussher's work include Cardiovascular Function and Risk Factors (42 papers), Adipose Tissue and Metabolism (36 papers) and Diabetes Treatment and Management (26 papers). John R. Ussher is often cited by papers focused on Cardiovascular Function and Risk Factors (42 papers), Adipose Tissue and Metabolism (36 papers) and Diabetes Treatment and Management (26 papers). John R. Ussher collaborates with scholars based in Canada, United States and United Kingdom. John R. Ussher's co-authors include Gary D. Lopaschuk, Daniel J. Drucker, Jagdip S. Jaswal, Clifford D.L. Folmes, William C. Stanley, Jason R.B. Dyck, Deborah M. Muoio, Timothy R. Koves, Olga Ilkayeva and Christopher B. Newgard and has published in prestigious journals such as Journal of Biological Chemistry, Circulation and Nature Medicine.

In The Last Decade

John R. Ussher

113 papers receiving 8.9k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Myocardial Fatty Acid Metabolism in Health and Disease

2010 1.6k citations Gary D. Lopaschuk, John R. Ussher et al. profile →
Mitochondrial Overload and Incomplete Fatty Acid Oxidation Contribute to Skeletal Muscle Insulin Resistance

2008 1.6k citations Timothy R. Koves, John R. Ussher et al. Cell Metabolism profile →
Glucagon-like peptide 1 receptor agonists: cardiovascular benefits and mechanisms of action

2023 282 citations John R. Ussher, Daniel J. Drucker profile →

Peers

John R. Ussher

PHYSI

CCM

EDM

SURGE

Augusto C. Montezano United Kingdom

Frank C. Brosius United States

Rebecca H. Ritchie Australia

Hiroshi Maegawa Japan

Sihem Boudina United States

Toyoshi Inoguchi Japan

Bernard Lassègue United States

Yasuo Ido United States

Matthew D. Breyer United States

Ryuichi Kikkawa Japan

Augusto C. Montezano United Kingdom

John R. Ussher

3.0k ×0.7

2.4k ×0.8

PHYSI

2.6k ×0.9

CCM

1.6k ×0.7

EDM

1.2k ×0.8

SURGE

Citations per year, relative to John R. Ussher John R. Ussher (= 1×) peers Augusto C. Montezano

Countries citing papers authored by John R. Ussher

Since Specialization

Citations

This map shows the geographic impact of John R. Ussher's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by John R. Ussher with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites John R. Ussher more than expected).

Fields of papers citing papers by John R. Ussher

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by John R. Ussher. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by John R. Ussher. The network helps show where John R. Ussher may publish in the future.

Co-authorship network of co-authors of John R. Ussher

This figure shows the co-authorship network connecting the top 25 collaborators of John R. Ussher. A scholar is included among the top collaborators of John R. Ussher based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with John R. Ussher. John R. Ussher is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Ussher, John R., et al.. (2026). Pharmacokinetics of Inhibitors of Succinyl-CoA:3-Ketoacid CoA Transferase in Sprague–Dawley Rats, and the Effect of a High-Fat Diet. The AAPS Journal. 28(2). 52–52.

Zhao, Yuan, Farah Eaton, Michelle Mendiola, et al.. (2025). Tumour initiated purinergic signalling promotes cardiomyocyte RBFOX1 degradation and cardiotoxicity from DNA damaging anticancer agents. Nature Communications. 16(1). 6861–6861.

Zhao, Yuan, Arno G. Siraki, Adam Kinnaird, et al.. (2025). Cysteine oxidation of a redox hub within complex I can facilitate electron transport chain supercomplex formation. Journal of Biological Chemistry. 301(9). 110555–110555.

Ussher, John R., et al.. (2025). The multifaceted roles of ketones in physiology. Experimental Physiology. 111(1). 1–13.

Greenwell, Amanda A., Cory S. Wagg, Farah Eaton, et al.. (2024). Pharmacological Inhibition of Succinyl Coenzyme A:3‐Ketoacid Coenzyme A Transferase Alleviates the Progression of Diabetic Cardiomyopathy. Journal of the American Heart Association. 13(7). e032697–e032697. 5 indexed citations

Greenwell, Amanda A., et al.. (2023). The antianginal ranolazine fails to improve glycaemia in obese liver‐specific pyruvate dehydrogenase deficient male mice. Basic & Clinical Pharmacology & Toxicology. 133(2). 194–201. 1 indexed citations

Greenwell, Amanda A., Farah Eaton, Peter A. Crawford, et al.. (2023). Ketone ester administration improves glycemia in obese mice. American Journal of Physiology-Cell Physiology. 325(3). C750–C757. 9 indexed citations

Greenwell, Amanda A., Kim L. Ho, Keshav Gopal, et al.. (2022). An isoproteic cocoa butter-based ketogenic diet fails to improve glucose homeostasis and promote weight loss in obese mice. American Journal of Physiology-Endocrinology and Metabolism. 323(1). E8–E20. 8 indexed citations

Gopal, Keshav, Nikole J. Byrne, Bruno Saleme, et al.. (2022). TRIM35-mediated degradation of nuclear PKM2 destabilizes GATA4/6 and induces P53 in cardiomyocytes to promote heart failure. Science Translational Medicine. 14(669). eabm3565–eabm3565. 18 indexed citations

10.

Ho, Kim L., Qutuba G. Karwi, David J. Connolly, et al.. (2022). Metabolic, structural and biochemical changes in diabetes and the development of heart failure. Diabetologia. 65(3). 411–423. 41 indexed citations

11.

Gopal, Keshav, Rami Al Batran, Tariq Altamimi, et al.. (2021). FoxO1 inhibition alleviates type 2 diabetes-related diastolic dysfunction by increasing myocardial pyruvate dehydrogenase activity. Cell Reports. 35(1). 108935–108935. 48 indexed citations

12.

Greenwell, Amanda A., Keshav Gopal, Tariq Altamimi, et al.. (2021). Barth syndrome-related cardiomyopathy is associated with a reduction in myocardial glucose oxidation. American Journal of Physiology-Heart and Circulatory Physiology. 320(6). H2255–H2269. 10 indexed citations

13.

Uddin, Golam M., Qutuba G. Karwi, Simran Pherwani, et al.. (2021). Deletion of BCATm increases insulin-stimulated glucose oxidation in the heart. Metabolism. 124. 154871–154871. 30 indexed citations

14.

Batran, Rami Al, et al.. (2019). Dietary-Induced Obesity, Hepatic Cytochrome P450, and Lidocaine Metabolism: Comparative Effects of High-Fat Diets in Mice and Rats and Reversibility of Effects With Normalization of Diet. Journal of Pharmaceutical Sciences. 109(2). 1199–1210. 16 indexed citations

15.

Gopal, Keshav, Malak Almutairi, Rami Al Batran, et al.. (2018). Cardiac-Specific Deletion of Pyruvate Dehydrogenase Impairs Glucose Oxidation Rates and Induces Diastolic Dysfunction. Frontiers in Cardiovascular Medicine. 5. 17–17. 34 indexed citations

16.

Ussher, John R., Laurie L. Baggio, Jonathan E. Campbell, et al.. (2014). Inactivation of the cardiomyocyte glucagon-like peptide-1 receptor (GLP-1R) unmasks cardiomyocyte-independent GLP-1R-mediated cardioprotection. Molecular Metabolism. 3(5). 507–517. 106 indexed citations

17.

Ali, Safina, John R. Ussher, Laurie L. Baggio, et al.. (2014). Cardiomyocyte glucagon receptor signaling modulates outcomes in mice with experimental myocardial infarction. Molecular Metabolism. 4(2). 132–143. 58 indexed citations

18.

Jaswal, Jagdip S., Wendy Keung, Wei Wang, John R. Ussher, & Gary D. Lopaschuk. (2011). Targeting fatty acid and carbohydrate oxidation — A novel therapeutic intervention in the ischemic and failing heart. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1813(7). 1333–1350. 303 indexed citations

19.

Zhang, Liyan, John R. Ussher, Tatsujiro Oka, et al.. (2010). Cardiac diacylglycerol accumulation in high fat-fed mice is associated with impaired insulin-stimulated glucose oxidation. Cardiovascular Research. 89(1). 148–156. 103 indexed citations

20.

Koves, Timothy R., John R. Ussher, Robert C. Noland, et al.. (2008). Mitochondrial Overload and Incomplete Fatty Acid Oxidation Contribute to Skeletal Muscle Insulin Resistance. Cell Metabolism. 7(1). 45–56. 1551 indexed citations breakdown →

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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