Andrew Fire

53.6k total citations · 16 hit papers
177 papers, 36.6k citations indexed

About

Andrew Fire is a scholar working on Molecular Biology, Aging and Genetics. According to data from OpenAlex, Andrew Fire has authored 177 papers receiving a total of 36.6k indexed citations (citations by other indexed papers that have themselves been cited), including 143 papers in Molecular Biology, 76 papers in Aging and 26 papers in Genetics. Recurrent topics in Andrew Fire's work include CRISPR and Genetic Engineering (78 papers), Genetics, Aging, and Longevity in Model Organisms (76 papers) and RNA Research and Splicing (25 papers). Andrew Fire is often cited by papers focused on CRISPR and Genetic Engineering (78 papers), Genetics, Aging, and Longevity in Model Organisms (76 papers) and RNA Research and Splicing (25 papers). Andrew Fire collaborates with scholars based in United States, Canada and United Kingdom. Andrew Fire's co-authors include Craig C. Mello, Mary K. Montgomery, Siqun Xu, Lisa Timmons, Susan Parrish, Phillip A. Sharp, Donald L. Court, William G. Kelly, Mark Samuels and Sheng‐Quan Xu and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Andrew Fire

176 papers receiving 35.6k citations

Hit Papers

Potent and specific genetic interference by double-s... 1980 2026 1995 2010 1998 2001 2001 1980 1999 2.5k 5.0k 7.5k 10.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
    1998 11.3k citations Andrew Fire, Craig C. Mello et al. Nature profile →
  2. Genes and Mechanisms Related to RNA Interference Regulate Expression of the Small Temporal RNAs that Control C. elegans Developmental Timing
    2001 1.5k citations Andrew Fire, Gary Ruvkun et al. Cell profile →
  3. Ingestion of bacterially expressed dsRNAs can produce specific and potent genetic interference in Caenorhabditis elegans
    2001 1.5k citations Lisa Timmons, Andrew Fire et al. profile →
  4. DNA-dependent transcription of adenovirus genes in a soluble whole-cell extract.
    1980 1.1k citations Andrew Fire et al. Proceedings of the National Academy of Sciences profile →
  5. The rde-1 Gene, RNA Interference, and Transposon Silencing in C. elegans
    1999 1.0k citations Hiroaki Tabara, Lisa Timmons et al. Cell profile →
  6. On the Role of RNA Amplification in dsRNA-Triggered Gene Silencing
    2001 971 citations Lisa Timmons, Andrew Fire et al. Cell profile →
  7. Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems
    2001 848 citations Andrew Fire et al. Proceedings of the National Academy of Sciences profile →
  8. Rolling replication of short DNA circles.
    1995 647 citations Andrew Fire et al. Proceedings of the National Academy of Sciences profile →
  9. Human tRNA-derived small RNAs in the global regulation of RNA silencing
    2010 574 citations Dirk Haussecker, Yong Huang et al. RNA profile →
  10. A modular set of lacZ fusion vectors for studying gene expression in Caenorhabditis elegans
    1990 560 citations Andrew Fire et al. profile →
  11. Efficient Marker-Free Recovery of Custom Genetic Modifications with CRISPR/Cas9 in Caenorhabditis elegans
    2014 546 citations Karen L. Artiles, Andrew Fire et al. Genetics profile →
  12. RNA-triggered gene silencing
    1999 481 citations Andrew Fire et al. profile →
  13. Distinct Populations of Primary and Secondary Effectors During RNAi in C. elegans
    2006 462 citations Julia Pak, Andrew Fire Science profile →
  14. Integrative transformation of Caenorhabditis elegans
    1986 357 citations Andrew Fire profile →
  15. [35] In Vitro transcription: Whole-cell extract
    1983 286 citations Andrew Fire et al. profile →
  16. Separation and characterization of factors mediating accurate transcription by RNA polymerase II.
    1982 283 citations Andrew Fire et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Andrew Fire United States 76 28.6k 9.1k 5.3k 4.6k 4.3k 177 36.6k
Craig C. Mello United States 55 21.6k 0.8× 6.7k 0.7× 5.0k 0.9× 4.1k 0.9× 2.7k 0.6× 95 26.4k
Ronald H.A. Plasterk Netherlands 90 23.7k 0.8× 5.3k 0.6× 5.3k 1.0× 9.0k 2.0× 4.4k 1.0× 193 31.6k
Victor Ambros United States 55 31.8k 1.1× 6.1k 0.7× 4.0k 0.8× 25.2k 5.5× 1.9k 0.4× 107 42.0k
Woodring E. Wright United States 99 28.4k 1.0× 4.4k 0.5× 2.1k 0.4× 2.4k 0.5× 4.1k 0.9× 294 43.5k
H. Robert Horvitz United States 107 31.7k 1.1× 21.2k 2.3× 2.8k 0.5× 12.6k 2.8× 3.0k 0.7× 252 51.6k
Calvin B. Harley United States 53 18.7k 0.7× 3.9k 0.4× 1.8k 0.3× 1.3k 0.3× 3.4k 0.8× 112 33.5k
Feng Zhang United States 86 76.6k 2.7× 4.6k 0.5× 7.7k 1.5× 4.0k 0.9× 14.9k 3.4× 181 85.6k
R Waterston United States 74 11.9k 0.4× 6.6k 0.7× 2.6k 0.5× 553 0.1× 3.3k 0.8× 155 17.3k
Eric A. Miska United Kingdom 65 25.2k 0.9× 2.1k 0.2× 2.7k 0.5× 15.9k 3.5× 2.8k 0.6× 161 31.6k
Yang Shi United States 94 30.9k 1.1× 1.5k 0.2× 1.7k 0.3× 7.1k 1.6× 4.8k 1.1× 205 36.6k

Countries citing papers authored by Andrew Fire

Since Specialization
Citations

This map shows the geographic impact of Andrew Fire's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Andrew Fire with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Andrew Fire more than expected).

Fields of papers citing papers by Andrew Fire

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Andrew Fire. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Andrew Fire. The network helps show where Andrew Fire may publish in the future.

Co-authorship network of co-authors of Andrew Fire

This figure shows the co-authorship network connecting the top 25 collaborators of Andrew Fire. A scholar is included among the top collaborators of Andrew Fire based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Andrew Fire. Andrew Fire is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Ambros, Victor, Martin Chalfie, Andrew Fire, et al.. (2025). From nematode to Nobel: How community-shared resources fueled the rise of Caenorhabditis elegans as a research organism. Proceedings of the National Academy of Sciences. 122(48). e2522808122–e2522808122. 1 indexed citations
2.
Shoura, Massa J., et al.. (2022). Context-dependent DNA polymerization effects can masquerade as DNA modification signals. BMC Genomics. 23(1). 249–249. 2 indexed citations
3.
Wahba, Lamia, Nimit Jain, Andrew Fire, et al.. (2020). An Extensive Meta-Metagenomic Search Identifies SARS-CoV-2-Homologous Sequences in Pangolin Lung Viromes. mSphere. 5(3). 42 indexed citations
4.
Wolf, Yuri I., Sukrit Silas, Yongjie Wang, et al.. (2020). Doubling of the known set of RNA viruses by metagenomic analysis of an aquatic virome. Nature Microbiology. 5(10). 1262–1270. 153 indexed citations
5.
Jain, Nimit, Lucas R. Blauch, Michał R. Szymański, et al.. (2020). Transcription polymerase–catalyzed emergence of novel RNA replicons. Science. 368(6487). 19 indexed citations
6.
Shoura, Massa J., et al.. (2019). Deconvolution of nucleic-acid length distributions: a gel electrophoresis analysis tool and applications. Nucleic Acids Research. 47(16). e92–e92. 9 indexed citations
7.
Artiles, Karen L., Andrew Fire, & Christian Frøkjær‐Jensen. (2019). Assessment and Maintenance of Unigametic Germline Inheritance for C. elegans. Developmental Cell. 48(6). 827–839.e9. 16 indexed citations
8.
Shoura, Massa J., Idan Gabdank, Loren Hansen, et al.. (2017). Intricate and Cell Type-Specific Populations of Endogenous Circular DNA (eccDNA) in Caenorhabditis elegans and Homo sapiens. G3 Genes Genomes Genetics. 7(10). 3295–3303. 79 indexed citations
9.
Stadler, Michael & Andrew Fire. (2013). Conserved Translatome Remodeling in Nematode Species Executing a Shared Developmental Transition. PLoS Genetics. 9(10). e1003739–e1003739. 36 indexed citations
10.
Pak, Julia, Jay M. Maniar, Cecilia C. Mello, & Andrew Fire. (2012). Protection from Feed-Forward Amplification in an Amplified RNAi Mechanism. Cell. 151(4). 885–899. 63 indexed citations
11.
Valouev, Anton, Steven Johnson, Scott D. Boyd, et al.. (2011). Determinants of nucleosome organization in primary human cells. Nature. 474(7352). 516–520. 482 indexed citations
12.
13.
Haussecker, Dirk, Yong Huang, Ashley Lau, et al.. (2010). Human tRNA-derived small RNAs in the global regulation of RNA silencing. RNA. 16(4). 673–695. 574 indexed citations breakdown →
14.
Sasaki, Shin, Cecilia C. Mello, Atsuko Shimada, et al.. (2008). Chromatin-Associated Periodicity in Genetic Variation Downstream of Transcriptional Start Sites. Science. 323(5912). 401–404. 104 indexed citations
15.
Lui, Weng‐Onn, Nader Pourmand, Bruce K. Patterson, & Andrew Fire. (2007). Patterns of Known and Novel Small RNAs in Human Cervical Cancer. Cancer Research. 67(13). 6031–6043. 376 indexed citations
16.
Parameswaran, Poornima, Roxana Jalili, Li Tao, et al.. (2007). A pyrosequencing-tailored nucleotide barcode design unveils opportunities for large-scale sample multiplexing. Nucleic Acids Research. 35(19). e130–e130. 271 indexed citations
17.
Fire, Andrew, Rosa Alcazar, & Frederick J. Tan. (2006). Unusual DNA Structures Associated With Germline Genetic Activity in Caenorhabditis elegans. Genetics. 173(3). 1259–1273. 51 indexed citations
18.
Pak, Julia & Andrew Fire. (2006). Distinct Populations of Primary and Secondary Effectors During RNAi in C. elegans. Science. 315(5809). 241–244. 462 indexed citations breakdown →
19.
Timmons, Lisa, Hiroaki Tabara, Craig C. Mello, & Andrew Fire. (2003). Inducible Systemic RNA Silencing in Caenorhabditis elegans. Molecular Biology of the Cell. 14(7). 2972–2983. 108 indexed citations
20.
Moerman, Donald G. & Andrew Fire. (1997). 16 Muscle: Structure, Function, and Development. Cold Spring Harbor Monograph Archive. 33. 417–470. 3 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact

Breakdown of academic impact, for papers by Craig C. Mello Breakdown of academic impact, for papers by Ronald H.A. Plasterk Breakdown of academic impact, for papers by Victor Ambros Breakdown of academic impact, for papers by Woodring E. Wright Breakdown of academic impact, for papers by H. Robert Horvitz Breakdown of academic impact, for papers by Calvin B. Harley Breakdown of academic impact, for papers by Feng Zhang Breakdown of academic impact, for papers by R Waterston Breakdown of academic impact, for papers by Eric A. Miska Breakdown of academic impact, for papers by Yang Shi
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