Jean‐Philippe Gratton

9.0k total citations · 1 hit paper
70 papers, 7.2k citations indexed

About

Jean‐Philippe Gratton is a scholar working on Molecular Biology, Physiology and Cell Biology. According to data from OpenAlex, Jean‐Philippe Gratton has authored 70 papers receiving a total of 7.2k indexed citations (citations by other indexed papers that have themselves been cited), including 45 papers in Molecular Biology, 39 papers in Physiology and 15 papers in Cell Biology. Recurrent topics in Jean‐Philippe Gratton's work include Nitric Oxide and Endothelin Effects (35 papers), Angiogenesis and VEGF in Cancer (13 papers) and Receptor Mechanisms and Signaling (12 papers). Jean‐Philippe Gratton is often cited by papers focused on Nitric Oxide and Endothelin Effects (35 papers), Angiogenesis and VEGF in Cancer (13 papers) and Receptor Mechanisms and Signaling (12 papers). Jean‐Philippe Gratton collaborates with scholars based in Canada, United States and Brazil. Jean‐Philippe Gratton's co-authors include William C. Sessa, David Fulton, Jason Fontana, Timothy J. McCabe, Kenneth Walsh, Andreas Papapetropoulos, Yasushi Fujio, Thomas Franke, Pascal Bernatchez and Manuel Morales‐Ruiz and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

In The Last Decade

Jean‐Philippe Gratton

70 papers receiving 7.1k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Regulation of endothelium-derived nitric oxide production by the protein kinase Akt

1999 2.2k citations David Fulton, Jean‐Philippe Gratton et al. Nature profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Jean‐Philippe Gratton Canada	39	4.0k	2.7k	1.4k	1.3k	908	70	7.2k
Richard C. Venema United States	48	2.9k 0.7×	2.7k 1.0×	1.4k 1.0×	925 0.7×	702 0.8×	77	6.0k
Chantal Dessy Belgium	43	3.1k 0.8×	2.1k 0.8×	1.8k 1.2×	901 0.7×	472 0.5×	103	7.0k
Markus Hecker Germany	53	3.2k 0.8×	4.1k 1.5×	2.2k 1.5×	692 0.5×	1.4k 1.5×	232	10.2k
Harold A. Singer United States	50	3.4k 0.8×	1.7k 0.6×	1.3k 0.9×	541 0.4×	474 0.5×	121	5.9k
Wolfgang Siess Germany	49	3.1k 0.8×	958 0.4×	1.8k 1.3×	683 0.5×	934 1.0×	157	8.0k
Belinda J. Michell Australia	27	4.4k 1.1×	2.7k 1.0×	849 0.6×	489 0.4×	358 0.4×	31	6.5k
Jason X.‐J. Yuan United States	60	5.5k 1.4×	2.1k 0.8×	2.9k 2.0×	433 0.3×	492 0.5×	199	11.8k
Fumikazu Okajima Japan	59	7.1k 1.8×	1.6k 0.6×	409 0.3×	1.8k 1.4×	1.2k 1.3×	197	9.9k
Chieko Mineo United States	44	3.6k 0.9×	1.1k 0.4×	871 0.6×	1.6k 1.3×	1.2k 1.3×	106	7.7k
Virginia J. Venema United States	32	2.9k 0.7×	1.5k 0.6×	916 0.6×	829 0.6×	405 0.4×	40	4.8k

Countries citing papers authored by Jean‐Philippe Gratton

Since Specialization

Citations

This map shows the geographic impact of Jean‐Philippe Gratton's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jean‐Philippe Gratton with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jean‐Philippe Gratton more than expected).

Fields of papers citing papers by Jean‐Philippe Gratton

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jean‐Philippe Gratton. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jean‐Philippe Gratton. The network helps show where Jean‐Philippe Gratton may publish in the future.

Co-authorship network of co-authors of Jean‐Philippe Gratton

This figure shows the co-authorship network connecting the top 25 collaborators of Jean‐Philippe Gratton. A scholar is included among the top collaborators of Jean‐Philippe Gratton based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Jean‐Philippe Gratton. Jean‐Philippe Gratton is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Goyette, Marie-Anne, Islam E. Elkholi, Hellen Kuasne, et al.. (2021). Targeting Axl favors an antitumorigenic microenvironment that enhances immunotherapy responses by decreasing Hif-1α levels. Proceedings of the National Academy of Sciences. 118(29). 51 indexed citations

Oubaha, Malika, Gaël Cagnone, Cécile Boscher, et al.. (2021). eNOS controls angiogenic sprouting and retinal neovascularization through the regulation of endothelial cell polarity. Cellular and Molecular Life Sciences. 79(1). 37–37. 44 indexed citations

Abu-Thuraia, Afnan, Marie-Anne Goyette, Jonathan Boulais, et al.. (2020). AXL confers cell migration and invasion by hijacking a PEAK1-regulated focal adhesion protein network. Nature Communications. 11(1). 3586–3586. 47 indexed citations

Boscher, Cécile, et al.. (2019). Polarization and sprouting of endothelial cells by angiopoietin-1 require PAK2 and paxillin-dependent Cdc42 activation. Molecular Biology of the Cell. 30(17). 2227–2239. 15 indexed citations

Goyette, Marie-Anne, Islam E. Elkholi, Afnan Abu-Thuraia, et al.. (2019). AXL knockdown gene signature reveals a drug repurposing opportunity for a class of antipsychotics to reduce growth and metastasis of triple-negative breast cancer. Oncotarget. 10(21). 2055–2067. 38 indexed citations

Chidiac, Rony, et al.. (2016). Comparative Phosphoproteomics Analysis of VEGF and Angiopoietin-1 Signaling Reveals ZO-1 as a Critical Regulator of Endothelial Cell Proliferation. Molecular & Cellular Proteomics. 15(5). 1511–1525. 22 indexed citations

Souza, Cleiton Martins, Dominique Davidson, Inmoo Rhee, et al.. (2012). The Phosphatase PTP-PEST/PTPN12 Regulates Endothelial Cell Migration and Adhesion, but Not Permeability, and Controls Vascular Development and Embryonic Viability. Journal of Biological Chemistry. 287(51). 43180–43190. 35 indexed citations

Pandey, Deepesh, Jean‐Philippe Gratton, Ruslan Rafikov, Stephen M. Black, & David Fulton. (2011). Calcium/Calmodulin-Dependent Kinase II Mediates the Phosphorylation and Activation of NADPH Oxidase 5. Molecular Pharmacology. 80(3). 407–415. 76 indexed citations

Desjardins, Fanny, et al.. (2010). Vascular Endothelial Growth Factor Receptor-2 Activates ADP-ribosylation Factor 1 to Promote Endothelial Nitric-oxide Synthase Activation and Nitric Oxide Release from Endothelial Cells. Journal of Biological Chemistry. 285(32). 24591–24599. 21 indexed citations

10.

Duval, Martine, Fabrice Le Bœuf, Jacques Huot, & Jean‐Philippe Gratton. (2007). Src-mediated Phosphorylation of Hsp90 in Response to Vascular Endothelial Growth Factor (VEGF) Is Required for VEGF Receptor-2 Signaling to Endothelial NO Synthase. Molecular Biology of the Cell. 18(11). 4659–4668. 116 indexed citations

11.

Oubaha, Malika, et al.. (2007). Phosphorylation of Tyrosine 801 of Vascular Endothelial Growth Factor Receptor-2 Is Necessary for Akt-dependent Endothelial Nitric-oxide Synthase Activation and Nitric Oxide Release from Endothelial Cells. Journal of Biological Chemistry. 282(14). 10660–10669. 67 indexed citations

12.

Blain, Jean‐François, et al.. (2005). A role for caveolin‐1 in post‐injury reactive neuronal plasticity. Journal of Neurochemistry. 92(4). 831–839. 54 indexed citations

13.

Papapetropoulos, Andreas, David Fulton, Michelle I. Lin, et al.. (2004). Vanadate Is a Potent Activator of Endothelial Nitric-Oxide Synthase: Evidence for the Role of the Serine/Threonine Kinase Akt and the 90-kDa Heat Shock Protein. Molecular Pharmacology. 65(2). 407–415. 43 indexed citations

14.

Gratton, Jean‐Philippe, Jun Yu, Jason W. Griffith, et al.. (2003). Cell-permeable peptides improve cellular uptake and therapeutic gene delivery of replication-deficient viruses in cells and in vivo. Nature Medicine. 9(3). 357–362. 153 indexed citations

15.

Morales‐Ruiz, Manuel, Menq-Jer Lee, Stefan Zöllner, et al.. (2001). Sphingosine 1-Phosphate Activates Akt, Nitric Oxide Production, and Chemotaxis through a GiProtein/Phosphoinositide 3-Kinase Pathway in Endothelial Cells. Journal of Biological Chemistry. 276(22). 19672–19677. 241 indexed citations

16.

Bukowski, John, et al.. (2001). The Sonic Hedgehog Receptor Patched Associates with Caveolin-1 in Cholesterol-rich Microdomains of the Plasma Membrane. Journal of Biological Chemistry. 276(22). 19503–19511. 116 indexed citations

17.

Fulton, David, Jean‐Philippe Gratton, Timothy J. McCabe, et al.. (1999). Regulation of endothelium-derived nitric oxide production by the protein kinase Akt. Nature. 399(6736). 597–601. 2179 indexed citations breakdown →

18.

Gratton, Jean‐Philippe, et al.. (1998). Endothelin-B Receptor-Dependent Modulation of the Pressor and Prostacyclin-Releasing Properties of Dynamically Converted Big Endothelin-1 in the Anesthetized Rabbit. Journal of Cardiovascular Pharmacology. 31. S161–S163. 6 indexed citations

19.

Gratton, Jean‐Philippe, et al.. (1995). Characterization of Endothelin Receptors and Endothelin-Converting Enzyme Activity in the Rabbit Lung. Journal of Cardiovascular Pharmacology. 26. S88–90. 9 indexed citations

20.

Télémaque, Sabine, et al.. (1993). Endothelin-1 induces vasoconstriction and prostacyclin release via the activation of endothelin ETA receptors in the perfused rabbit kidney. European Journal of Pharmacology. 237(2-3). 275–281. 32 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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