David J. Carini

7.1k total citations · 3 hit papers
51 papers, 6.0k citations indexed

About

David J. Carini is a scholar working on Molecular Biology, Organic Chemistry and Cardiology and Cardiovascular Medicine. According to data from OpenAlex, David J. Carini has authored 51 papers receiving a total of 6.0k indexed citations (citations by other indexed papers that have themselves been cited), including 28 papers in Molecular Biology, 20 papers in Organic Chemistry and 14 papers in Cardiology and Cardiovascular Medicine. Recurrent topics in David J. Carini's work include Receptor Mechanisms and Signaling (16 papers), Renin-Angiotensin System Studies (13 papers) and Chemical Synthesis and Analysis (9 papers). David J. Carini is often cited by papers focused on Receptor Mechanisms and Signaling (16 papers), Renin-Angiotensin System Studies (13 papers) and Chemical Synthesis and Analysis (9 papers). David J. Carini collaborates with scholars based in United States. David J. Carini's co-authors include Andrew T. Chiu, Pancras C. Wong, Ruth R. Wexler, A.L. Johnson, John V. Duncia, William A. Price, Pieter B.M.W.M. Timmermans, William F. Herblin, P.B.M.W.M. Timmermans and Roger Smith and has published in prestigious journals such as Chemical Reviews, Journal of the American Chemical Society and Biochemical and Biophysical Research Communications.

In The Last Decade

David J. Carini

51 papers receiving 5.7k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Angiotensin II receptors and angiotensin II receptor antagonists.

1993 1.6k citations P.B.M.W.M. Timmermans, Pancras C. Wong et al. profile →
Identification of angiotensin II receptor subtypes

1989 705 citations Andrew T. Chiu, William F. Herblin et al. Biochemical and Biophysical Research Communications profile →
Nonpeptide angiotensin II receptor antagonists: the discovery of a series of N-(biphenylylmethyl)imidazoles as potent, orally active antihypertensives

1991 369 citations David J. Carini, John V. Duncia et al. Journal of Medicinal Chemistry profile →

Peers

Countries citing papers authored by David J. Carini

Since Specialization

Citations

This map shows the geographic impact of David J. Carini's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David J. Carini with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David J. Carini more than expected).

Fields of papers citing papers by David J. Carini

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David J. Carini. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David J. Carini. The network helps show where David J. Carini may publish in the future.

Co-authorship network of co-authors of David J. Carini

This figure shows the co-authorship network connecting the top 25 collaborators of David J. Carini. A scholar is included among the top collaborators of David J. Carini based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with David J. Carini. David J. Carini is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Inhibitors of HIV-1 attachment: The discovery and structure–activity relationships of tetrahydroisoquinolines as replacements for the piperazine benzamide in the 3-glyoxylyl 6-azaindole pharmacophore 2015 ·Bioorganic & Medicinal Chemistry Letters ·Jacob J. Swidorski, Zheng Liu, Zhiwei Yin, Tao Wang, David J. Carini, Sandhya Rahematpura, Ming Zheng, Kim A. Johnson, Sharon Zhang, Pin‐Fang Lin, Dawn D. Parker, Wenying Li, Nicholas A. Meanwell, Lawrence G. Hamann, Alicia Regueiro‐Ren	22
2	The Discovery and Development of Angiotensin II Antagonists 2006 ·Kluwer Academic Publishers eBooks ·David J. Carini, David D. Christ, John V. Duncia, Michael E. Pierce	12
3	Developments in Antiviral Drug Design, Discovery and Development in 2004 2005 ·PubMed ·Nicholas A. Meanwell, Makonen Belema, David J. Carini, Stanley V. D’Andrea, John F. Kadow, Mark Krystal, B. Narasimhulu Naidu, Alicia Regueiro‐Ren, Paul M. Scola, Sing‐Yuen Sit, Michael Walker, Tao Wang, Kap‐Sun Yeung	4
4	Identification of selective inhibitors of cyclin dependent kinase 4 2001 ·Bioorganic & Medicinal Chemistry Letters ·David J. Carini, Robert F. Kaltenbach, Jie Liu, Pamela A. Benfield, John F. Boylan, Michael D. Boisclair, Leonardo Brizuela, Catherine R. Burton, Sarah Cox, Robert H. Grafström, Barbara Harrison, (unknown), (unknown), Jay A. Markwalder, Yuki Nakano, Steven P. Seitz, (unknown), George L. Trainor, Thais M. Sielecki	37
5	Pharmacology and Pharmacokinetics of A Novel Nonpeptide Angiotensin II Receptor Antagonist–DMP 811 1995 ·Clinical and Experimental Hypertension ·Pancras C. Wong, Shiew‐Mei Huang, Robert Ardecky, David J. Carini, Andrew T. Chiu, William A. Price, (unknown), Ruth R. Wexler, (unknown), Wendy Timmermans	3
6	Balanced angiotensin II receptor antagonists. III. The effects of substitution at the imidazole 5-position. 1994 ·Bioorganic & Medicinal Chemistry Letters ·Joseph B. Santella, John V. Duncia, Carol L. Ensinger, (unknown), David J. Carini, Ruth R. Wexler, Andrew T. Chiu, Pancras C. Wong, Pieter B.M.W.M. Timmermans	14
7	The discovery of DuP 753, a potent, orally active nonpeptide angiotensin II receptor antagonist 1992 ·Medicinal Research Reviews ·John V. Duncia, David J. Carini, Andrew T. Chiu, A.L. Johnson, William A. Price, Pancras C. Wong, Ruth R. Wexler, Pieter B.M.W.M. Timmermans	173
8	In Vivo Pharmacology of DuP 753 1991 ·American Journal of Hypertension ·Pancras C. Wong, William A. Price, Andrew T. Chiu, John V. Duncia, David J. Carini, Ruth R. Wexler, A.L. Johnson, Pieter B.M.W.M. Timmermans	99
9	Pharmacology of DuP 532, a selective and noncompetitive AT1 receptor antagonist. 1991 ·Journal of Pharmacology and Experimental Therapeutics ·Pancras C. Wong, (unknown), (unknown), William F. Herblin, David J. Carini, Roger Smith, Ruth R. Wexler, P.B.M.W.M. Timmermans	42
10	The Discovery of a New Class of Highly Specific Nonpeptide Angiotensin II Receptor Antagonists 1991 ·American Journal of Hypertension ·Pieter B.M.W.M. Timmermans, David J. Carini, Andrew T. Chiu, John V. Duncia, William A. Price, Gregory J. Wells, Pancras C. Wong, A.L. Johnson, Ruth R. Wexler	46
11	In Vitro Pharmacology of DuP 753 1991 ·American Journal of Hypertension ·Andrew T. Chiu, Dale E. McCall, William A. Price, Pancras C. Wong, David J. Carini, John V. Duncia, Ruth R. Wexler, Sung Eun Yoo, A.L. Johnson, Pieter B.M.W.M. Timmermans	44
12	Angiotensin II Receptor Heterogeneity 1991 ·American Journal of Hypertension ·William F. Herblin, Andrew T. Chiu, Dale E. McCall, Robert Ardecky, David J. Carini, John V. Duncia, Lori J. Pease, Pancras C. Wong, Ruth R. Wexler, A.L. Johnson, Pieter B.M.W.M. Timmermans	50
13	Angiotensin II receptor antagonists. From discovery to antihypertensive drugs. 1991 ·Hypertension ·P.B.M.W.M. Timmermans, David J. Carini, Andrew T. Chiu, John V. Duncia, William A. Price, Gregory J. Wells, Pancras C. Wong, Ruth R. Wexler, A.L. Johnson	64
14	DuP 532: A second generation of nonpeptide angiotensin II receptor antagonists 1991 ·Biochemical and Biophysical Research Communications ·Andrew T. Chiu, David J. Carini, John V. Duncia, Kam H. Leung, Dale E. McCall, William A. Price, Pancras C. Wong, Ronald D. Smith, Ruth R. Wexler, Pieter B.M.W.M. Timmermans, Raymond S.L. Chang, Victor J. Lotti	64
15	The discovery of potent nonpeptide angiotensin II receptor antagonists: a new class of potent antihypertensives 1990 ·Journal of Medicinal Chemistry ·John V. Duncia, Andrew T. Chiu, David J. Carini, (unknown), A.L. Johnson, William A. Price, Gregory J. Wells, P C Wong, Joseph C. Calabrese, Pieter B.M.W.M. Timmermans	187
16	Nonpeptide angiotensin II receptor antagonists. XI. Pharmacology of EXP3174: an active metabolite of DuP 753, an orally active antihypertensive agent. 1990 ·Journal of Pharmacology and Experimental Therapeutics ·Pancras C. Wong, William A. Price, Andrew T. Chiu, John V. Duncia, David J. Carini, Ruth R. Wexler, A.L. Johnson, P B Timmermans	292
17	Nonpeptide Angiotensin II Receptor Antagonists 1990 ·American Journal of Hypertension ·Pieter B.M.W.M. Timmermans, David J. Carini, Andrew T. Chiu, John V. Duncia, William A. Price, Gregory J. Wells, Pancras C. Wong, Ruth R. Wexler, A.L. Johnson	51
18	Identification of angiotensin II receptor subtypes breakdown → 1989 ·Biochemical and Biophysical Research Communications ·Andrew T. Chiu, William F. Herblin, Dale E. McCall, Robert Ardecky, David J. Carini, John V. Duncia, Lori J. Pease, Pancras C. Wong, Ruth R. Wexler, A.L. Johnson, Pieter B.M.W.M. Timmermans	705
19	Discrimination of angiotensin II receptor subtypes by dithiothreitol 1989 ·European Journal of Pharmacology ·Andrew T. Chiu, Dale E. McCall, Tâm Nguyễn, David J. Carini, John V. Duncia, William F. Herblin, Roy T. Uyeda, P C Wong, Ruth R. Wexler, A.L. Johnson, (unknown)	112
20	Non-peptide angiotensin II receptor antagonists. II . Pharmacology of S-8308 1988 ·European Journal of Pharmacology ·Andrew T. Chiu, David J. Carini, A.L. Johnson, Dale E. McCall, William A. Price, Martin Thoolen, Pancras C. Wong, Robert I. Taber, Pieter B.M.W.M. Timmermans	63

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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