Mei-Chu Lo

2.3k total citations · 1 hit paper
19 papers, 957 citations indexed

About

Mei-Chu Lo is a scholar working on Molecular Biology, Organic Chemistry and Computational Theory and Mathematics. According to data from OpenAlex, Mei-Chu Lo has authored 19 papers receiving a total of 957 indexed citations (citations by other indexed papers that have themselves been cited), including 17 papers in Molecular Biology, 3 papers in Organic Chemistry and 3 papers in Computational Theory and Mathematics. Recurrent topics in Mei-Chu Lo's work include Glycosylation and Glycoproteins Research (3 papers), Computational Drug Discovery Methods (3 papers) and Ubiquitin and proteasome pathways (3 papers). Mei-Chu Lo is often cited by papers focused on Glycosylation and Glycoproteins Research (3 papers), Computational Drug Discovery Methods (3 papers) and Ubiquitin and proteasome pathways (3 papers). Mei-Chu Lo collaborates with scholars based in United States, Canada and United Kingdom. Mei-Chu Lo's co-authors include Ann Aulabaugh, George A. Ellestad, Guixian Jin, Michael S. Malamas, Rebecca Cowling, Jonathan Bard, Suzanne Walker, Victor J. Cee, John D. McCarter and Ryan P. Wurz and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of the American Chemical Society and Journal of Biological Chemistry.

In The Last Decade

Mei-Chu Lo

18 papers receiving 937 citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Evaluation of fluorescence-based thermal shift assays for hit identification in drug discovery

2004 533 citations Mei-Chu Lo, Ann Aulabaugh et al. Analytical Biochemistry profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Mei-Chu Lo United States	11	750	132	117	97	77	19	957
Jörg Bomke Germany	13	572 0.8×	94 0.7×	104 0.9×	75 0.8×	108 1.4×	15	816
Guixian Jin United States	15	714 1.0×	264 2.0×	108 0.9×	75 0.8×	90 1.2×	21	1.1k
Yaxue Zhao China	17	782 1.0×	121 0.9×	161 1.4×	63 0.6×	70 0.9×	44	1.2k
Maria Fälth Savitski Germany	8	1.2k 1.6×	130 1.0×	134 1.1×	67 0.7×	178 2.3×	10	1.5k
M.J. Romanowski United States	21	1.0k 1.4×	261 2.0×	101 0.9×	124 1.3×	95 1.2×	37	1.4k
Brent M. Dorr United States	12	965 1.3×	200 1.5×	116 1.0×	83 0.9×	72 0.9×	14	1.2k
Mark Ammirati United States	14	598 0.8×	169 1.3×	173 1.5×	69 0.7×	121 1.6×	20	1.2k
Yehuda Goldgur United States	19	1.4k 1.8×	180 1.4×	149 1.3×	114 1.2×	53 0.7×	50	2.0k
Krisna C. Duong‐Ly United States	13	609 0.8×	87 0.7×	62 0.5×	63 0.6×	73 0.9×	21	877
Siân Rowsell United Kingdom	12	725 1.0×	292 2.2×	245 2.1×	119 1.2×	71 0.9×	13	1.1k

Countries citing papers authored by Mei-Chu Lo

Since Specialization

Citations

This map shows the geographic impact of Mei-Chu Lo's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Mei-Chu Lo with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Mei-Chu Lo more than expected).

Fields of papers citing papers by Mei-Chu Lo

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Mei-Chu Lo. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Mei-Chu Lo. The network helps show where Mei-Chu Lo may publish in the future.

Co-authorship network of co-authors of Mei-Chu Lo

This figure shows the co-authorship network connecting the top 25 collaborators of Mei-Chu Lo. A scholar is included among the top collaborators of Mei-Chu Lo based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Mei-Chu Lo. Mei-Chu Lo is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

19 of 19 papers shown

Fotsch, Christopher, Ryan Case, Chen‐Tung Arthur Chen, et al.. (2024). Creating a more strategic small molecule biophysical hit characterization workflow. SLAS DISCOVERY. 29(4). 100159–100159.

Jackson, Jeffrey J., Aaron C. Siegmund, Wen‐Ju Bai, et al.. (2023). Imidazolone as an Amide Bioisostere in the Development of β-1,3-N-Acetylglucosaminyltransferase 2 (B3GNT2) Inhibitors. Journal of Medicinal Chemistry. 66(23). 16120–16140. 10 indexed citations

Murray, Justin K., Lei Liu, Michael Ollmann, et al.. (2021). Identification and Optimization of a Minor Allele-Specific siRNA to Prevent PNPLA3 I148M-Driven Nonalcoholic Fatty Liver Disease. Nucleic Acid Therapeutics. 31(5). 324–340. 15 indexed citations

Das, Amrita, et al.. (2020). An Automated High-Throughput Fluorescence In Situ Hybridization (FISH) Assay Platform for Use in the Identification and Optimization of siRNA-Based Therapeutics. SLAS DISCOVERY. 26(2). 281–291. 2 indexed citations

Hao, Yue, Amandine Créquer, Hao Chen, et al.. (2020). Structures and mechanism of human glycosyltransferase β1,3-N-acetylglucosaminyltransferase 2 (B3GNT2), an important player in immune homeostasis. Journal of Biological Chemistry. 296. 100042–100042. 23 indexed citations

Wurz, Ryan P., Mei-Chu Lo, John D. McCarter, et al.. (2017). A “Click Chemistry Platform” for the Rapid Synthesis of Bispecific Molecules for Inducing Protein Degradation. Journal of Medicinal Chemistry. 61(2). 453–461. 150 indexed citations

Thomasson, Bobbie, et al.. (2016). Development of a scintillation proximity binding assay for high-throughput screening of hematopoietic prostaglandin D2 synthase. Analytical Biochemistry. 511. 17–23. 4 indexed citations

Xia, Fang, et al.. (2015). Development of a nucleotide sugar purification method using a mixed mode column & mass spectrometry detection. Journal of Pharmaceutical and Biomedical Analysis. 115. 402–409. 7 indexed citations

Wang, Yingcai, Jieping Zhu, Jiwen Liu, et al.. (2014). Optimization beyond AMG 232: Discovery and SAR of sulfonamides on a piperidinone scaffold as potent inhibitors of the MDM2-p53 protein–protein interaction. Bioorganic & Medicinal Chemistry Letters. 24(16). 3782–3785. 13 indexed citations

10.

Lo, Mei-Chu, Kang Dai, Cong Li, et al.. (2011). Development of a time-resolved fluorescence resonance energy transfer assay for cyclin-dependent kinase 4 and identification of its ATP-noncompetitive inhibitors. Analytical Biochemistry. 421(2). 368–377. 5 indexed citations

11.

Lo, Mei-Chu, Minghan Wang, Ki Won Kim, et al.. (2008). A highly sensitive high-throughput luminescence assay for malonyl-CoA decarboxylase. Analytical Biochemistry. 376(1). 122–130. 2 indexed citations

12.

Lo, Mei-Chu, Ann Aulabaugh, Guixian Jin, et al.. (2004). Evaluation of fluorescence-based thermal shift assays for hit identification in drug discovery. Analytical Biochemistry. 332(1). 153–159. 533 indexed citations breakdown →

13.

Lo, Mei-Chu, Ann Aulabaugh, Girija Krishnamurthy, et al.. (2004). Probing the Interaction of HTI-286 with Tubulin Using a Stilbene Analogue. Journal of the American Chemical Society. 126(32). 9898–9899. 7 indexed citations

14.

Krishnamurthy, Girija, Wendy H.Y. Cheng, Mei-Chu Lo, et al.. (2003). Biophysical Characterization of the Interactions of HTI-286 with Tubulin Heterodimer and Microtubules. Biochemistry. 42(46). 13484–13495. 17 indexed citations

15.

Olland, Andrea, Kathryn Underwood, Robert Czerwiński, et al.. (2002). Identification, Characterization, and Crystal Structure ofBacillus subtilis Nicotinic Acid Mononucleotide Adenylyltransferase. Journal of Biological Chemistry. 277(5). 3698–3707. 49 indexed citations

16.

Lo, Mei-Chu, et al.. (2001). A New Structure for the Substrate-Binding Antibiotic Ramoplanin. Journal of the American Chemical Society. 123(35). 8640–8641. 32 indexed citations

17.

Ha, Sha, Emmanuel J. Chang, Mei-Chu Lo, et al.. (1999). The Kinetic Characterization of Escherichia coli MurG Using Synthetic Substrate Analogues. Journal of the American Chemical Society. 121(37). 8415–8426. 68 indexed citations

18.

Lo, Mei-Chu, Sha Ha, István Pelczer, Santona Pal, & Suzanne Walker. (1998). The solution structure of the DNA-binding domain of Skn-1. Proceedings of the National Academy of Sciences. 95(15). 8455–8460. 12 indexed citations

19.

Pal, Santona, et al.. (1997). Skn-1: Evidence for a bipartite recognition helix in DNA binding. Proceedings of the National Academy of Sciences. 94(11). 5556–5561. 8 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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