Daniel C. Douek

74.6k total citations · 22 hit papers
338 papers, 44.9k citations indexed

About

Daniel C. Douek is a scholar working on Immunology, Virology and Infectious Diseases. According to data from OpenAlex, Daniel C. Douek has authored 338 papers receiving a total of 44.9k indexed citations (citations by other indexed papers that have themselves been cited), including 251 papers in Immunology, 145 papers in Virology and 76 papers in Infectious Diseases. Recurrent topics in Daniel C. Douek's work include Immune Cell Function and Interaction (180 papers), T-cell and B-cell Immunology (147 papers) and HIV Research and Treatment (143 papers). Daniel C. Douek is often cited by papers focused on Immune Cell Function and Interaction (180 papers), T-cell and B-cell Immunology (147 papers) and HIV Research and Treatment (143 papers). Daniel C. Douek collaborates with scholars based in United States, United Kingdom and Australia. Daniel C. Douek's co-authors include Jason M. Brenchley, Richard A. Koup, David A. Price, Mario Roederer, Brenna J. Hill, Michael R. Betts, Steven G. Deeks, Louis J. Picker, Timothy W. Schacker and Joseph P. Casazza and has published in prestigious journals such as Nature, Science and New England Journal of Medicine.

In The Last Decade

Daniel C. Douek

332 papers receiving 44.2k citations

Hit Papers

Microbial translocation i... 1998 2026 2007 2016 2006 1998 2011 2004 2009 500 1000 1.5k 2.0k 2.5k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Microbial translocation is a cause of systemic immune activation in chronic HIV infection
    2006 2.7k citations Jason M. Brenchley, David A. Price et al. profile →
  2. Changes in thymic function with age and during the treatment of HIV infection
    1998 1.5k citations Daniel C. Douek, Ashley T. Haase et al. profile →
  3. A human memory T cell subset with stem cell–like properties
    2011 1.4k citations Máire F. Quigley, Jorge R. Almeida et al. profile →
  4. CD4+ T Cell Depletion during all Stages of HIV Disease Occurs Predominantly in the Gastrointestinal Tract
    2004 1.4k citations Jason M. Brenchley, Timothy W. Schacker et al. The Journal of Experimental Medicine profile →
  5. HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation
    2009 1.3k citations Nicolas Chomont, Jason M. Brenchley et al. profile →
  6. Sensitive and viable identification of antigen-specific CD8+ T cells by a flow cytometric assay for degranulation
    2003 1.3k citations Michael R. Betts, Jason M. Brenchley et al. profile →
  7. Massive infection and loss of memory CD4+ T cells in multiple tissues during acute SIV infection
    2005 989 citations Daniel C. Douek, Mario Roederer et al. profile →
  8. HIV preferentially infects HIV-specific CD4+ T cells
    2002 982 citations Daniel C. Douek, Jason M. Brenchley et al. profile →
  9. Plasma Levels of Soluble CD14 Independently Predict Mortality in HIV Infection
    2011 856 citations Netanya G. Sandler, Jason M. Brenchley et al. profile →
  10. Impaired TH17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome
    2008 848 citations Jason M. Brenchley, Daniel C. Douek et al. profile →
  11. Expression of CD57 defines replicative senescence and antigen-induced apoptotic death of CD8+ T cells
    2003 812 citations Jason M. Brenchley, Michael R. Betts et al. Blood profile →
  12. PD-1 identifies the patient-specific CD8+ tumor-reactive repertoire infiltrating human tumors
    2014 772 citations Alena Gros, Paul F. Robbins et al. Journal of Clinical Investigation profile →
  13. Preexisting influenza-specific CD4+ T cells correlate with disease protection against influenza challenge in humans
    2012 766 citations Daniel C. Douek et al. profile →
  14. PD-1 is a regulator of virus-specific CD8+ T cell survival in HIV infection
    2006 725 citations Joseph P. Casazza, Jason M. Brenchley et al. The Journal of Experimental Medicine profile →
  15. Systemic Effects of Inflammation on Health during Chronic HIV Infection
    2013 588 citations Steven G. Deeks, Daniel C. Douek et al. profile →
  16. Analysis of Total Human Immunodeficiency Virus (HIV)-Specific CD4 + and CD8 + T-Cell Responses: Relationship to Viral Load in Untreated HIV Infection
    2001 574 citations Michael R. Betts, David R. Ambrozak et al. Journal of Virology profile →
  17. Superior control of HIV-1 replication by CD8+ T cells is reflected by their avidity, polyfunctionality, and clonal turnover
    2007 542 citations Jorge R. Almeida, David A. Price et al. The Journal of Experimental Medicine profile →
  18. Relationship between T Cell Activation and CD4 + T Cell Count in HIV‐Seropositive Individuals with Undetectable Plasma HIV RNA Levels in the Absence of Therapy
    2007 506 citations Peter W. Hunt, Jason M. Brenchley et al. profile →
  19. Persistent HIV-1 replication is associated with lower antiretroviral drug concentrations in lymphatic tissues
    2014 503 citations Gregory J. Beilman, Alexander Khoruts et al. Proceedings of the National Academy of Sciences profile →
  20. Plasma Levels of Bacterial DNA Correlate with Immune Activation and the Magnitude of Immune Restoration in Persons with Antiretroviral‐Treated HIV Infection
    2009 463 citations Peter W. Hunt, Jeffrey N. Martin et al. profile →
  21. Microbial translocation in HIV infection: causes, consequences and treatment opportunities
    2012 352 citations Netanya G. Sandler, Daniel C. Douek profile →
  22. SARS-CoV-2 variant prediction and antiviral drug design are enabled by RBD in vitro evolution
    2021 230 citations Matthew Gagné, Robert A. Seder et al. Nature Microbiology profile →

Author Peers

Peers are selected by citation overlap in the author's most active subfields. citations · hero ref

Author Last Decade Papers Cites
Daniel C. Douek 26.6k 19.1k 11.1k 9.5k 6.2k 338 44.9k
Richard A. Koup 24.4k 0.9× 22.9k 1.2× 13.9k 1.3× 9.4k 1.0× 6.4k 1.0× 309 42.6k
Jason M. Brenchley 14.8k 0.6× 13.8k 0.7× 7.7k 0.7× 6.0k 0.6× 4.1k 0.7× 184 26.6k
Mario Roederer 20.3k 0.8× 7.7k 0.4× 6.3k 0.6× 7.3k 0.8× 9.8k 1.6× 347 36.9k
Louis J. Picker 16.9k 0.6× 8.0k 0.4× 4.0k 0.4× 6.5k 0.7× 4.7k 0.8× 199 29.2k
Steven G. Deeks 12.6k 0.5× 27.4k 1.4× 22.4k 2.0× 10.0k 1.0× 5.6k 0.9× 567 45.1k
Barton F. Haynes 16.7k 0.6× 14.9k 0.8× 8.5k 0.8× 5.7k 0.6× 8.5k 1.4× 432 34.7k
Mario Clerici 11.1k 0.4× 9.6k 0.5× 6.8k 0.6× 6.2k 0.7× 6.2k 1.0× 676 30.0k
Alan Landay 10.0k 0.4× 12.7k 0.7× 9.1k 0.8× 6.6k 0.7× 4.1k 0.7× 525 27.3k
Mary Carrington 21.1k 0.8× 10.7k 0.6× 5.4k 0.5× 6.1k 0.6× 4.0k 0.6× 359 32.3k
Michael M. Lederman 8.4k 0.3× 13.1k 0.7× 9.8k 0.9× 6.4k 0.7× 3.2k 0.5× 381 24.7k

Countries citing papers authored by Daniel C. Douek

Since Specialization
Citations

This map shows the geographic impact of Daniel C. Douek's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Daniel C. Douek with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Daniel C. Douek more than expected).

Fields of papers citing papers by Daniel C. Douek

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Daniel C. Douek. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Daniel C. Douek. The network helps show where Daniel C. Douek may publish in the future.

Co-authorship network of co-authors of Daniel C. Douek

This figure shows the co-authorship network connecting the top 25 collaborators of Daniel C. Douek. A scholar is included among the top collaborators of Daniel C. Douek based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Daniel C. Douek. Daniel C. Douek is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Machmach, Kawthar, Rohit Farmer, Sucheta Godbole, et al.. (2025). NK cell activation and CD4+ T cell α4β7 expression are associated with susceptibility to HIV-1. Journal of Clinical Investigation. 135(15).
2.
3.
Spaulding, Alicen B., Kevin Messacar, Matthew R. Vogt, et al.. (2024). Recruitment and retention of pediatric participants for pandemic preparedness research: Experience from the PREMISE EV-D68 Pilot Study. Contemporary Clinical Trials Communications. 41. 101351–101351.
4.
Chaimongkol, Natthawan, Bianca M. Nagata, Samuel Darko, et al.. (2024). A non-human primate model for human norovirus infection. Nature Microbiology. 9(3). 776–786. 7 indexed citations
5.
Yogev, Ohad, Omer Weissbrod, Giorgia Battistoni, et al.. (2023). From a genome-wide screen of RNAi molecules against SARS-CoV-2 to a validated broad-spectrum and potent prophylaxis. Communications Biology. 6(1). 277–277. 6 indexed citations
6.
Singh, Satya P., Hongwei H. Zhang, Jinguo Chen, et al.. (2023). Human CCR6+ Th Cells Show Both an Extended Stable Gradient of Th17 Activity and Imprinted Plasticity. The Journal of Immunology. 210(11). 1700–1716. 5 indexed citations
7.
Schramm, Chaim A., Noemia S. Lima, Kristin L. Boswell, et al.. (2023). Interaction dynamics between innate and adaptive immune cells responding to SARS-CoV-2 vaccination in non-human primates. Nature Communications. 14(1). 7961–7961. 5 indexed citations
8.
Fahad, Ahmed S., Sheila N. López Acevedo, Bharat Madan, et al.. (2021). Immortalization and functional screening of natively paired human T cell receptor repertoires. Protein Engineering Design and Selection. 35. 5 indexed citations
9.
Wegrecki, Marcin, T. Praveena, Lijing Bu, et al.. (2021). The molecular assembly of the marsupial γμ T cell receptor defines a third T cell lineage. Science. 371(6536). 1383–1388. 16 indexed citations
10.
Furth, Noa, Adina Weinberger, Amiel A. Dror, et al.. (2021). Unified platform for genetic and serological detection of COVID-19 with single-molecule technology. PLoS ONE. 16(7). e0255096–e0255096. 2 indexed citations
11.
Horsburgh, Bethany A., Eunok Lee, Bonnie Hiener, et al.. (2020). High levels of genetically intact HIV in HLA-DR+ memory T cells indicates their value for reservoir studies. AIDS. 34(5). 659–668. 30 indexed citations
12.
Mina, Michael J., C. Jessica E. Metcalf, Adrian B. McDermott, et al.. (2020). A Global Immunological Observatory to meet a time of pandemics. eLife. 9. 51 indexed citations
13.
Pasetto, Anna, Alena Gros, Paul F. Robbins, et al.. (2016). Tumor- and Neoantigen-Reactive T-cell Receptors Can Be Identified Based on Their Frequency in Fresh Tumor. Cancer Immunology Research. 4(9). 734–743. 148 indexed citations
14.
Breed, Matthew W., Andrea P. O. Jordan, Pyone P. Aye, et al.. (2012). Loss of a Tyrosine-Dependent Trafficking Motif in the Simian Immunodeficiency Virus Envelope Cytoplasmic Tail Spares Mucosal CD4 Cells but Does Not Prevent Disease Progression. Journal of Virology. 87(3). 1528–1543. 27 indexed citations
15.
Mendoza, Daniel, Laura E. Ruff, David R. Ambrozak, et al.. (2012). HLA B*5701-Positive Long-Term Nonprogressors/Elite Controllers Are Not Distinguished from Progressors by the Clonal Composition of HIV-Specific CD8 + T Cells. Journal of Virology. 86(7). 4014–4018. 20 indexed citations
16.
Favre, David, Jeff E. Mold, Peter W. Hunt, et al.. (2010). Tryptophan Catabolism by Indoleamine 2,3-Dioxygenase 1 Alters the Balance of T H 17 to Regulatory T Cells in HIV Disease. Science Translational Medicine. 2(32). 32ra36–32ra36. 423 indexed citations
17.
Almeida, Jorge R., Delphine Sauce, David A. Price, et al.. (2009). Antigen sensitivity is a major determinant of CD8+ T-cell polyfunctionality and HIV-suppressive activity. Blood. 113(25). 6351–6360. 160 indexed citations
18.
Venturi, Vanessa, Katherine Kedzierska, David A. Price, et al.. (2006). Sharing of T cell receptors in antigen-specific responses is driven by convergent recombination. Proceedings of the National Academy of Sciences. 103(49). 18691–18696. 129 indexed citations
19.
Brenchley, Jason M., Timothy W. Schacker, Laura E. Ruff, et al.. (2004). CD4+ T Cell Depletion during all Stages of HIV Disease Occurs Predominantly in the Gastrointestinal Tract. The Journal of Experimental Medicine. 200(6). 749–759. 1353 indexed citations breakdown →
20.
Betts, Michael R., David R. Ambrozak, Daniel C. Douek, et al.. (2001). Analysis of Total Human Immunodeficiency Virus (HIV)-Specific CD4 + and CD8 + T-Cell Responses: Relationship to Viral Load in Untreated HIV Infection. Journal of Virology. 75(24). 11983–11991. 574 indexed citations breakdown →

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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