Robert S. Mittler

9.8k total citations · 2 hit papers
105 papers, 8.2k citations indexed

About

Robert S. Mittler is a scholar working on Immunology, Radiology, Nuclear Medicine and Imaging and Oncology. According to data from OpenAlex, Robert S. Mittler has authored 105 papers receiving a total of 8.2k indexed citations (citations by other indexed papers that have themselves been cited), including 93 papers in Immunology, 21 papers in Radiology, Nuclear Medicine and Imaging and 19 papers in Oncology. Recurrent topics in Robert S. Mittler's work include Immune Cell Function and Interaction (65 papers), T-cell and B-cell Immunology (65 papers) and Immunotherapy and Immune Responses (42 papers). Robert S. Mittler is often cited by papers focused on Immune Cell Function and Interaction (65 papers), T-cell and B-cell Immunology (65 papers) and Immunotherapy and Immune Responses (42 papers). Robert S. Mittler collaborates with scholars based in United States, South Korea and Germany. Robert S. Mittler's co-authors include Lieping Chen, Anthony T. Vella, Ignacio Melero, Alejandro Aruffo, Michael K. Hoffmann, Walter W. Shuford, Jeffrey A. Ledbetter, Chikara Takahashi, Karl Erik Hellström and Jeff Bradshaw and has published in prestigious journals such as Science, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

In The Last Decade

Robert S. Mittler

105 papers receiving 7.9k citations

Hit Papers

Monoclonal antibodies against the 4-1BB T-cell activation... 1997 2026 2006 2016 1997 1997 200 400 600
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Monoclonal antibodies against the 4-1BB T-cell activation molecule eradicate established tumors
    1997 727 citations Alejandro Aruffo, Robert S. Mittler et al. profile →
  2. 4-1BB Costimulatory Signals Preferentially Induce CD8+ T Cell Proliferation and Lead to the Amplification In Vivo of Cytotoxic T Cell Responses
    1997 649 citations Anthony W. Siadak, T J Brown et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Robert S. Mittler United States 50 6.4k 2.6k 1.5k 746 515 105 8.2k
John R. Yannelli United States 34 5.5k 0.9× 3.6k 1.4× 2.2k 1.4× 597 0.8× 793 1.5× 74 7.3k
Giulia Casorati Italy 48 5.8k 0.9× 2.1k 0.8× 1.5k 0.9× 429 0.6× 843 1.6× 131 7.4k
Paolo Dellabona Italy 46 5.7k 0.9× 2.5k 1.0× 1.2k 0.8× 486 0.7× 446 0.9× 130 7.6k
Matthew F. Mescher United States 43 5.7k 0.9× 1.8k 0.7× 1.3k 0.8× 418 0.6× 358 0.7× 86 6.9k
Isabelle Durand France 41 6.9k 1.1× 1.8k 0.7× 1.2k 0.8× 328 0.4× 283 0.5× 56 8.4k
Richard J. Armitage United States 45 7.1k 1.1× 1.8k 0.7× 1.6k 1.1× 712 1.0× 484 0.9× 75 9.3k
Daniel L. Mueller United States 42 4.9k 0.8× 1.3k 0.5× 1.5k 1.0× 551 0.7× 543 1.1× 83 6.6k
Danila Valmori Switzerland 53 8.0k 1.2× 2.6k 1.0× 2.9k 1.9× 764 1.0× 465 0.9× 139 9.5k
Clive R. Wood United States 21 5.2k 0.8× 4.4k 1.7× 1.8k 1.2× 663 0.9× 394 0.8× 35 8.4k
Roberto S. Accolla Italy 41 3.9k 0.6× 1.2k 0.5× 1.4k 0.9× 1.4k 1.9× 421 0.8× 179 5.8k

Countries citing papers authored by Robert S. Mittler

Since Specialization
Citations

This map shows the geographic impact of Robert S. Mittler's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Robert S. Mittler with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Robert S. Mittler more than expected).

Fields of papers citing papers by Robert S. Mittler

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Robert S. Mittler. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Robert S. Mittler. The network helps show where Robert S. Mittler may publish in the future.

Co-authorship network of co-authors of Robert S. Mittler

This figure shows the co-authorship network connecting the top 25 collaborators of Robert S. Mittler. A scholar is included among the top collaborators of Robert S. Mittler based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Robert S. Mittler. Robert S. Mittler is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Adams, David E., Yuehong Wu, Robert S. Mittler, et al.. (2013). Recombinant soluble CD137 prevents type one diabetes in nonobese diabetic mice. Journal of Autoimmunity. 47. 94–103. 31 indexed citations
2.
Engram, Jessica C., Barbara Cervasi, José A. M. Borghans, et al.. (2010). Lineage-specific T-cell reconstitution following in vivo CD4+ and CD8+ lymphocyte depletion in nonhuman primates. Blood. 116(5). 748–758. 25 indexed citations
3.
Zhang, Benyue, et al.. (2010). Dendritic Cells and Stat3 Are Essential for CD137-Induced CD8 T Cell Activation-Induced Cell Death. The Journal of Immunology. 184(9). 4770–4778. 25 indexed citations
4.
Kim, Young H., Beom K. Choi, Ho S. Oh, et al.. (2009). Mechanisms involved in synergistic anticancer effects of anti-4-1BB and cyclophosphamide therapy. Molecular Cancer Therapeutics. 8(2). 469–478. 41 indexed citations
5.
Lee, Seung‐Woo, Shahram Salek‐Ardakani, Robert S. Mittler, & Michael Croft. (2009). Hypercostimulation through 4-1BB Distorts Homeostasis of Immune Cells. The Journal of Immunology. 182(11). 6753–6762. 49 indexed citations
6.
Robertson, Shelly J., Ronald J. Messer, Aaron Carmody, et al.. (2008). CD137 costimulation of CD8+ T cells confers resistance to suppression by virus-induced regulatory cells (Journal of Immunology (2008) 180 (5267-5274)). The Journal of Immunology. 181(2). 14 indexed citations
7.
Robertson, Shelly J., Ronald J. Messer, Aaron Carmody, et al.. (2008). CD137 Costimulation of CD8+ T Cells Confers Resistance to Suppression by Virus-Induced Regulatory T Cells. The Journal of Immunology. 180(8). 5267–5274. 40 indexed citations
8.
Bandyopadhyay, Suman, Meixiao Long, Adam T. Hagymasi, et al.. (2008). Self-Antigen Prevents CD8 T Cell Effector Differentiation by CD134 and CD137 Dual Costimulation. The Journal of Immunology. 181(11). 7728–7737. 15 indexed citations
9.
Lee, Seungjoo, Robert J. Rossi, Sun‐Kyeong Lee, et al.. (2007). CD134 Costimulation Couples the CD137 Pathway to Induce Production of Supereffector CD8 T Cells That Become IL-7 Dependent. The Journal of Immunology. 179(4). 2203–2214. 48 indexed citations
10.
Zhang, Benyue & Robert S. Mittler. (2007). CD137 crosslinking mediates effector T cell death and immune suppression during LCMV infection (B126). The Journal of Immunology. 178(1_Supplement). LB26–LB26. 1 indexed citations
11.
Ménoret, Antoine, Lara Myers, Seungjoo Lee, et al.. (2006). TGFβ Protein Processing and Activity through TCR Triggering of Primary CD8+ T Regulatory Cells. The Journal of Immunology. 177(9). 6091–6097. 25 indexed citations
12.
Wohlfert, Elizabeth A., Leonid Gorelik, Robert S. Mittler, Richard A. Flavell, & Robert B. Clark. (2006). Cutting Edge: Deficiency in the E3 Ubiquitin Ligase Cbl-b Results in a Multifunctional Defect in T Cell TGF-β Sensitivity In Vitro and In Vivo. The Journal of Immunology. 176(3). 1316–1320. 119 indexed citations
13.
Fukushima, Atsuki, Tomoko Yamaguchi, Waka Ishida, et al.. (2005). Engagement of 4-1BB Inhibits the Development of Experimental Allergic Conjunctivitis in Mice. The Journal of Immunology. 175(8). 4897–4903. 53 indexed citations
14.
Myers, Lara, Michael Croft, Byoung S. Kwon, Robert S. Mittler, & Anthony T. Vella. (2005). Peptide-Specific CD8 T Regulatory Cells Use IFN-γ to Elaborate TGF-β-Based Suppression. The Journal of Immunology. 174(12). 7625–7632. 88 indexed citations
15.
Foell, Juergen, Shawn P. O’Neil, Megan McCausland, et al.. (2003). CD137 costimulatory T cell receptor engagement reverses acute disease in lupus-prone NZB × NZW F1 mice. Journal of Clinical Investigation. 111(10). 1505–1518. 133 indexed citations
16.
Foell, Juergen, Shawn P. O’Neil, Megan McCausland, et al.. (2003). CD137 costimulatory T cell receptor engagement reverses acute disease in lupus-prone NZB × NZW F1 mice. Journal of Clinical Investigation. 111(10). 1505–1518. 145 indexed citations
17.
Wilcox, Ryan A., Andrei I. Chapoval, Kevin Gorski, et al.. (2002). Cutting Edge: Expression of Functional CD137 Receptor by Dendritic Cells. The Journal of Immunology. 168(9). 4262–4267. 189 indexed citations
18.
Diehl, Linda, Geertje J. D. van Mierlo, Annemieke Th. den Boer, et al.. (2002). In Vivo Triggering Through 4-1BB Enables Th-Independent Priming of CTL in the Presence of an Intact CD28 Costimulatory Pathway. The Journal of Immunology. 168(8). 3755–3762. 75 indexed citations
19.
Tan, Joyce T., Jason K. Whitmire, Kaja Murali‐Krishna, et al.. (2000). 4-1BB Costimulation Is Required for Protective Anti-Viral Immunity After Peptide Vaccination. The Journal of Immunology. 164(5). 2320–2325. 121 indexed citations
20.
Ledbetter, J A, J A Francisco, Clay B. Siegall, et al.. (1997). Agonistic activity of a CD40-specific single-chain Fv constructed from the variable regions of mAb G28-5.. PubMed. 17(5-6). 427–35. 5 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact

Breakdown of academic impact, for papers by John R. Yannelli Breakdown of academic impact, for papers by Giulia Casorati Breakdown of academic impact, for papers by Paolo Dellabona Breakdown of academic impact, for papers by Matthew F. Mescher Breakdown of academic impact, for papers by Isabelle Durand Breakdown of academic impact, for papers by Richard J. Armitage Breakdown of academic impact, for papers by Daniel L. Mueller Breakdown of academic impact, for papers by Danila Valmori Breakdown of academic impact, for papers by Clive R. Wood Breakdown of academic impact, for papers by Roberto S. Accolla
Rankless by CCL
2026