Jan Wehkamp

14.7k citations

159 papers · 11.2k indexed · 3 hit papers · h-index 51

Impact in

Microbiology top 0.05%
- Antimicrobial Peptides and Activities
Immunology top 0.5%
- Immune Response and Inflammation
- IL-33, ST2, and ILC Pathways

Papers in

Microbiology 74
- Antimicrobial Peptides and Activities 74
Emergency Medical Services 23
- Pediatric health and respiratory diseases 23

Co-authors: Eduard F. Stange Klaus Fellermann Sabine Nuding Charles Bevins Jürgen Harder Matthias Schwab Miriam Schlee Klaus Herrlinger
Journals: Gastroenterology (14 papers)Journal of Crohn s and Colitis (10 papers)Inflammatory Bowel Diseases (7 papers)Frontiers in Immunology (5 papers)Mucosal Immunology (5 papers)
Partner nations: Germany United States Denmark

In The Last Decade

Jan Wehkamp

153 papers receiving 11.0k citations

Hit Papers

align trajectories log scale

Secukinumab, a human anti-IL-17A monoclonal antibody, for moderate to severe Crohn's disease: unexpected results of a randomised, double-blind placebo-controlled trial 2012 · 1.2k citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2012 Gut
2005 Proceedings of the National Academy of Sciences
2004 Gut

Peers

Countries citing papers authored by Jan Wehkamp

Since Specialization

Citations

This map shows the geographic impact of Jan Wehkamp's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jan Wehkamp with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jan Wehkamp more than expected).

Fields of papers citing papers by Jan Wehkamp

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jan Wehkamp. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jan Wehkamp. The network helps show where Jan Wehkamp may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Jan Wehkamp, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Jan Wehkamp Line = papers co-authored together Jan Wehkamp links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Host defense peptides human β defensin 2 and LL-37 ameliorate murine necrotizing enterocolitis iScience ·Denis Brnadeau-Moreau, Amy H. Stanford, Jennifer Berger, Huiyu Gong, S.A. Mohammed, Benjamin A. H. Jensen, Peter Nordkild, Eveliina Myllymaa, Jan Wehkamp, Mark A. Underwood, Steven J. McElroy	2024	4
2	Using Computer Vision to Improve Endoscopic Disease Quantification in Therapeutic Clinical Trials of Ulcerative Colitis Gastroenterology ·Ryan W. Stidham, Jorge Juárez Rosales, Shuyang Cheng, H. Brommer, 宾东华, I. J. Reeve, Michael Rice, Shrinivas Bishu, Jan Wehkamp, А. В. Ткачев, Najat Khan, Aleksandar Stojmirović, Louis R. Ghanem, Kayvan Najarian	2023	30
3	Mo1736 PREDICTING REMISSION EARLY IN ULCERATIVE COLITIS CLINICAL TRIALS USING COMPUTER VISION ANALYSIS OF ENDOSCOPIC VIDEO Gastroenterology ·Yunqing He, Michael Twaits, Lorena Guale Alcivar, Jorge Juárez Rosales, Shuyang Cheng, H. Brommer, 宾东华, Michael Rice, Shrinivas Bishu, Jan Wehkamp, Najat Khan, Tommaso Mansi, Xiaoying Wu, А. В. Ткачев, Aleksandar Stojmirović, Louis R. Ghanem, Kayvan Najarian	2023	1
4	Proteolytic Degradation of reduced Human Beta Defensin 1 generates a Novel Antibiotic Octapeptide Scientific Reports ·Aaron David Tucker, Bjoern O. Schroeder, Sahithi Rudrabhatla, Laérico Antônio Gonçalves Jacovine, Daniela Mailänder‐Sánchez, 英一琴岡, Naraynam Srikanth, Martin Schaller, Eduard F. Stange, Nisar P. Malek, Christopher Weidenmaier, Salomé LeibundGut‐Landmann, Jan Wehkamp	2019	19
5	Histone deacetylase-mediated regulation of the antimicrobial peptide hBD2 differs in intestinal cell lines and cultured tissue Scientific Reports ·M. BARTELS, Maureen J. Ostaff, Eduard F. Stange, Nisar P. Malek, Jan Wehkamp	2018	15
6	Human Endogenous Retroviruses: Residues of Ancient Times Are Differentially Expressed in Crohn’s Disease Inflammatory Intestinal Diseases ·Thomas Klag, Paweł Nawrocki, Maureen J. Ostaff, German Ott, Eduard F. Stange, Nisar P. Malek, Wolfgang Seifarth, Jan Wehkamp	2018	8
7	Inflammatory Bowel Disease: Crohn’s disease and ulcerative colitis Deutsches Ärzteblatt international ·Jan Wehkamp, Martín Götz, Klaus Herrlinger, Wolfgang Steurer, Eduard F. Stange	2016	124
8	Correction: Bacteria Regulate Intestinal Epithelial Cell Differentiation Factors Both In Vitro and In Vivo PLoS ONE ·Sven Becker, Tobias A. Oelschlaeger, Andy Wullaert, Katerina Vlantis, Manolis Pasparakis, Jan Wehkamp, Eduard F. Stange, Michael Gersemann	2013	12
9	Gastric Antimicrobial Peptides Fail to Eradicate Helicobacter pylori Infection Due to Selective Induction and Resistance PLoS ONE ·Sabine Nuding, Michael Gersemann, Yoshio Hosaka, J. J. Po-An Hsieh, Christian Schaefer, Julia Beisner, Bjoern O. Schroeder, Maureen J. Ostaff, FJM Rietmeijer, German Ott, Martin Schaller, Eduard F. Stange, Jan Wehkamp	2013	33
10	Human α-Defensin 6 Promotes Mucosal Innate Immunity Through Self-Assembled Peptide Nanonets Science ·Hiutung Chu, Marzena Pazgier, Grace Jung, Sean‐Paul Nuccio, Patricia A. Castillo, Maarten F. de Jong, Maria G. Winter, Sebastian Winter, Jan Wehkamp, Bo Shen, Nita H. Salzman, Mark A. Underwood, Renée M. Tsolis, Glenn M. Young, Wuyuan Lu, Robert I. Lehrer, Andreas J. Bäumler, Charles Bevins	2012	328
11	Secukinumab, a human anti-IL-17A monoclonal antibody, for moderate to severe Crohn's disease: unexpected results of a randomised, double-blind placebo-controlled trial Gut ·Wolfgang Hueber, Bruce E. Sands, Steve Lewitzky, Marc Vandemeulebroecke, Walter Reinisch, Peter Higgins, Jan Wehkamp, Brian G. Feagan, Michael Yao, Marek Karczewski, Jacek Karczewski, Nicole Pezous, Stephan Bek, Gerard Bruin, E. Muret, C Berger, Marco Londei, Arthur P. Bertolino, Gervais Tougas, Simon Travis, (unknown) Hit paper breakdown →	2012	1156
12	From intestinal stem cells to inflammatory bowel diseases. PubMed ·Michael Gersemann, Eduard F. Stange, Jan Wehkamp	2011	79
13	Peroxisome proliferator-activated receptor gamma activation is required for maintenance of innate antimicrobial immunity in the colon Proceedings of the National Academy of Sciences ·Laurent Peyrin‐Biroulet, Julia Beisner, Guoxing Wang, Sabine Nuding, محمود أحمد عبد اللطيف, D. F. Kelly, Erika Parmentier-Decrucq, Rodrigue Dessein, Emilie Mérour, Philippe Chavatte, Teddy Grandjean, Aude Bressenot, Pierre Desreumaux, Jean–Frédéric Colombel, Béatrice Desvergne, Eduard F. Stange, Jan Wehkamp, Mathias Chamaillard	2010	161
14	Genetic Variants of Wnt Transcription Factor TCF-4 (TCF7L2) Putative Promoter Region Are Associated with Small Intestinal Crohn's Disease PLoS ONE ·Maureen J. Koslowski, Irmgard Kübler, Mathias Chamaillard, Elke Schaeffeler, Walter Reinisch, Guoxing Wang, Julia Beisner, Alexander Teml, Laurent Peyrin‐Biroulet, Stefan Winter, Klaus Herrlinger, Paul Rutgeerts, Séverine Vermeire, Rachel Cooney, Klaus Fellermann, Derek P. Jewell, Charles Bevins, Matthias Schwab, Eduard F. Stange, Jan Wehkamp	2009	101
15	Antibacterial activity of human defensins on anaerobic intestinal bacterial species: a major role of HBD-3 Microbes and Infection ·Sabine Nuding, Lutz Zabel, Corinne Enders, Edith Porter, Klaus Fellermann, Jan Wehkamp, Andrés Pérez Moreno, Eduard F. Stange	2009	44
16	Differences in goblet cell differentiation between Crohn's disease and ulcerative colitis Differentiation ·Michael Gersemann, Sven Becker, Irmgard Kübler, Maureen J. Koslowski, Guoxing Wang, Klaus Herrlinger, Joscha Griger, Péter Fritz, Klaus Fellermann, Matthias Schwab, Jan Wehkamp, Eduard F. Stange	2009	221
17	Antimicrobial host defense in the upper gastrointestinal tract European Journal of Gastroenterology & Hepatology ·Yoshio Hosaka, Maureen J. Koslowski, Sabine Nuding, Guoxing Wang, Miriam Schlee, Christian Schäfer, FJM Rietmeijer, Eduard F. Stange, Jan Wehkamp	2008	15
18	The Paneth Cell α-Defensin Deficiency of Ileal Crohn’s Disease Is Linked to Wnt/Tcf-4 The Journal of Immunology ·Jan Wehkamp, Guoxing Wang, Irmgard Kübler, Sabine Nuding, Alex Gregorieff, Anke Schnabel, Robert J. Kays, Klaus Fellermann, Oliver Burk, Matthias Schwab, Hans Clevers, Charles Bevins, Eduard F. Stange	2007	220
19	Paneth cells and the innate immune response Current Opinion in Gastroenterology ·Jan Wehkamp, Eduard F. Stange	2006	32
20	Reduced Paneth cell α-defensins in ileal Crohn's disease Proceedings of the National Academy of Sciences ·Jan Wehkamp, Nita H. Salzman, Edith Porter, Sabine Nuding, Michael Weichenthal, Robert E. Petras, Bo Shen, Elke Schaeffeler, Matthias Schwab, Rose Linzmeier, Ryan W. Feathers, Hiutung Chu, Heriberto Lima, Klaus Fellermann, Tomas Ganz, Eduard F. Stange, Charles Bevins Hit paper breakdown →	2005	749

About Jan Wehkamp

Jan Wehkamp is a scholar working on Microbiology, Emergency Medical Services, Immunology, Genetics and Food Science, having authored 159 papers that have together received 11.2k indexed citations. Recurring topics across this work include Antimicrobial Peptides and Activities (74 papers), Inflammatory Bowel Disease (45 papers), Probiotics and Fermented Foods (32 papers), Immune Response and Inflammation (28 papers), Pediatric health and respiratory diseases (23 papers), Gut microbiota and health (20 papers), Infant Nutrition and Health (19 papers) and Helicobacter pylori-related gastroenterology studies (16 papers). The work is most often cited by research in Microbiology (2.9k citations), Immunology (3.6k citations), Gastroenterology (685 citations), Genetics (3.2k citations) and Emergency Medical Services (791 citations). Jan Wehkamp has collaborated with scholars based in Germany, United States and Denmark. Frequent co-authors include Eduard F. Stange, Klaus Fellermann, Sabine Nuding, Charles Bevins, Jürgen Harder, Matthias Schwab, Miriam Schlee, Klaus Herrlinger, Michael Gersemann and Maureen J. Ostaff. Their work appears in journals such as Gastroenterology, Journal of Crohn s and Colitis, Inflammatory Bowel Diseases, Frontiers in Immunology and Mucosal Immunology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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