James M. Staddon

4.8k total citations · 2 hit papers
52 papers, 3.7k citations indexed

About

James M. Staddon is a scholar working on Molecular Biology, Neurology and Physiology. According to data from OpenAlex, James M. Staddon has authored 52 papers receiving a total of 3.7k indexed citations (citations by other indexed papers that have themselves been cited), including 33 papers in Molecular Biology, 10 papers in Neurology and 9 papers in Physiology. Recurrent topics in James M. Staddon's work include Barrier Structure and Function Studies (8 papers), Wnt/β-catenin signaling in development and cancer (6 papers) and Microbial infections and disease research (5 papers). James M. Staddon is often cited by papers focused on Barrier Structure and Function Studies (8 papers), Wnt/β-catenin signaling in development and cancer (6 papers) and Microbial infections and disease research (5 papers). James M. Staddon collaborates with scholars based in United Kingdom, Japan and United States. James M. Staddon's co-authors include Lee L. Rubin, Caroline Smales, Tetsuaki Hirase, Shöichiro Tsukita, Enrique Rozengurt, Kurt Herrenknecht, Richard G. Hansford, Alistair J. Lax, Kazushi Fujimoto and Mikio Furuse and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and The Journal of Cell Biology.

In The Last Decade

James M. Staddon

52 papers receiving 3.7k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

THE CELL BIOLOGY OF THE BLOOD-BRAIN BARRIER

1999 771 citations Lee L. Rubin, James M. Staddon profile →
Occludin as a possible determinant of tight junction permeability in endothelial cells

1997 517 citations Tetsuaki Hirase, James M. Staddon et al. profile →

Peers

Countries citing papers authored by James M. Staddon

Since Specialization

Citations

This map shows the geographic impact of James M. Staddon's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by James M. Staddon with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites James M. Staddon more than expected).

Fields of papers citing papers by James M. Staddon

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by James M. Staddon. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by James M. Staddon. The network helps show where James M. Staddon may publish in the future.

Co-authorship network of co-authors of James M. Staddon

This figure shows the co-authorship network connecting the top 25 collaborators of James M. Staddon. A scholar is included among the top collaborators of James M. Staddon based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with James M. Staddon. James M. Staddon is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	High-content phenotypic screen to identify small molecule enhancers of Parkin-dependent ubiquitination and mitophagy 2023 ·SLAS DISCOVERY ·Roberta Tufi, Emily H. Clark, Tamaki Hoshikawa, (unknown), (unknown), (unknown), James M. Staddon, Thomas Briston	7
2	Identification of pyrimidinyl piperazines as non-iminosugar glucocerebrosidase (GCase) pharmacological chaperones 2023 ·Bioorganic & Medicinal Chemistry Letters ·Tamaki Hoshikawa, Tôru Watanabe, (unknown), (unknown), (unknown), Siân Lewis, Thomas Briston, (unknown), James M. Staddon, (unknown), Anthony H.V. Schapira, Andrew K. Takle	1
3	Advancing novel therapies for neurodegeneration through an innovative model for industry–academia collaborations: A decade of the Eisai–UCL experience 2023 ·Drug Discovery Today ·Peter J. Atkinson, (unknown), Nicola Ridgway, Malcolm C. Roberts, (unknown), Thomas T. Warner, James M. Staddon, Andrew K. Takle	1
4	Microglial signalling pathway deficits associated with the patient derived R47H TREM2 variants linked to AD indicate inability to activate inflammasome 2021 ·Scientific Reports ·Katharina Cosker, Anna Mallach, (unknown), Thomas M. Piers, James M. Staddon, Stephen J. Neame, John Hardy, Jennifer M. Pocock	32
5	Mitochondrial permeability transition pore: sensitivity to opening and mechanistic dependence on substrate availability 2017 ·Scientific Reports ·Thomas Briston, Malcolm C. Roberts, Siân Lewis, (unknown), James M. Staddon, György Szabadkai, Michael R. Duchen	119
6	Identification of ER-000444793, a Cyclophilin D-independent inhibitor of mitochondrial permeability transition, using a high-throughput screen in cryopreserved mitochondria 2016 ·Scientific Reports ·Thomas Briston, Siân Lewis, (unknown), Kavita Mistry, Yongchun Shen, (unknown), (unknown), (unknown), Michael R. Duchen, György Szabadkai, James M. Staddon, Malcolm C. Roberts, (unknown)	23
7	Amphiphysin I phosphorylation on residue threonine 260 in a pentylenetetrazole-induced seizure model 2008 ·Neuroscience Letters ·(unknown), Oliver Kleiner, Raymond Chung, (unknown), Louise Morgan, Toshal R. Patel, James M. Staddon	1
8	Inflammation and dephosphorylation of the tight junction protein occludin in an experimental model of multiple sclerosis 2007 ·Neuroscience ·Louise Morgan, Bina Shah, (unknown), (unknown), Anthony Groom, R. Chung, Daniel R. Higazi, H. Desmond, Terence Smith, James M. Staddon	94
9	Development of a pentylenetetrazole-induced seizure model to evaluate kinase inhibitor efficacy in the central nervous system 2005 ·Neuroscience Letters ·Louise Morgan, Stephen J. Neame, Hannah Child, Raymond Chung, Bina Shah, (unknown), James M. Staddon, Toshal R. Patel	6
10	High-throughput methods to detect dimerization of Bcl-2 family proteins 2003 ·Analytical Biochemistry ·Jonathan R. Whitfield, (unknown), Catherine Bardelle, James M. Staddon	9
11	Regulation of Tight Junction Permeability and Occludin Phosphorylation by RhoA-p160ROCK-dependent and -independent Mechanisms 2001 ·Journal of Biological Chemistry ·Tetsuaki Hirase, Seinosuke Kawashima, Elaine Y.M. Wong, Tomomi Ueyama, Yoshiyuki Rikitake, Shöichiro Tsukita, Mitsuhiro Yokoyama, James M. Staddon	250
12	Cyclic AMP Blocks Bacterial Lipopolysaccharide-Induced Myosin Light Chain Phosphorylation in Endothelial Cells Through Inhibition of Rho/Rho Kinase Signaling 2000 ·The Journal of Immunology ·Markus Essler, James M. Staddon, Christian Weber, Martin Aepfelbacher	131
13	Treatment with BBB022A or rolipram stabilizes the blood-brain barrier in experimental autoimmune encephalomyelitis: an additional mechanism for the therapeutic effect of type IV phosphodiesterase inhibitors 1999 ·Journal of Neuroimmunology ·Virginia A Folcik, Terry J. Smith, (unknown), Julie A. Kawczak, Bin Zhu, Hideki Sakurai, (unknown), James M. Staddon, Andrzej Głąbiński, Ann Chernosky, Marie Tani, Justin M. Johnson, Vincent K. Tuohy, Lee L. Rubin, Richard M. Ransohoff	51
14	Phosphodiesterase 4 Conformers: Preparation of Recombinant Enzymes and Assay for Inhibitors 1999 ·Analytical Biochemistry ·Catherine Bardelle, Caroline Smales, Masashi Ito, K. Nomoto, Elaine Y.M. Wong, Hiroyuki Kato, T. Saeki, James M. Staddon	12
15	Dephosphorylation of the catenins p120 and p100 in endothelial cells in response to inflammatory stimuli 1999 ·Biochemical Journal ·M. Ratcliffe, Caroline Smales, James M. Staddon	9
16	Protein phosphorylation and the regulation of cell-cell junctions in brain endothelial cells. 1997 ·PubMed ·James M. Staddon, M. Ratcliffe, Louise Morgan, Tetsuaki Hirase, Caroline Smales, Lee L. Rubin	11
17	Lysophosphatidic Acid Increases Tight Junction Permeability in Cultured Brain Endothelial Cells 1997 ·Journal of Neurochemistry ·Charlotte Schulze, Caroline Smales, Lee L. Rubin, James M. Staddon	140
18	Effects of Age and Adenosine in the Modulation of Insulin Action on Rat Adipocyte Metabolism 1990 ·Journal of Gerontology ·(unknown), (unknown), James M. Staddon, Ellen M. Rogus, Andrew P. Goldberg	16
19	Sequence analysis of the potent mitogenic toxin of Pasteurella multocida 1990 ·FEBS Letters ·Alistair J. Lax, N. Chanter, Gillian D. Pullinger, Theresa Higgins, James M. Staddon, Enrique Rozengurt	37
20	Evidence indicating that the glucagon‐induced increase in cytoplasmic free Ca²⁺ concentration in hepatocytes is mediated by an increase in cyclic AMP concentration 1989 ·European Journal of Biochemistry ·James M. Staddon, Richard G. Hansford	55

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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