Mikio Furuse

39.1k total citations · 20 hit papers
160 papers, 31.0k citations indexed

About

Mikio Furuse is a scholar working on Neurology, Molecular Biology and Cell Biology. According to data from OpenAlex, Mikio Furuse has authored 160 papers receiving a total of 31.0k indexed citations (citations by other indexed papers that have themselves been cited), including 128 papers in Neurology, 108 papers in Molecular Biology and 35 papers in Cell Biology. Recurrent topics in Mikio Furuse's work include Barrier Structure and Function Studies (125 papers), Connexins and lens biology (72 papers) and Neurological Disease Mechanisms and Treatments (34 papers). Mikio Furuse is often cited by papers focused on Barrier Structure and Function Studies (125 papers), Connexins and lens biology (72 papers) and Neurological Disease Mechanisms and Treatments (34 papers). Mikio Furuse collaborates with scholars based in Japan, United States and Germany. Mikio Furuse's co-authors include Shöichiro Tsukita, Masahiko Itoh, Hiroyuki Sasaki, Kazushi Fujimoto, Kazumasa Morita, Kyoko Furuse, Shigenobu Yonemura, Tetsuaki Hirase, Mitinori Saitou and Akira Nagafuchi and has published in prestigious journals such as Cell, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

In The Last Decade

Mikio Furuse

159 papers receiving 30.5k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Occludin: a novel integral membrane protein localizing at tight junctions.

1993 2.1k citations Mikio Furuse, Masahiko Itoh et al. The Journal of Cell Biology profile →
Multifunctional strands in tight junctions

2001 2.1k citations Shöichiro Tsukita, Mikio Furuse et al. Nature Reviews Molecular Cell Biology profile →
Claudin-1 and -2: Novel Integral Membrane Proteins Localizing at Tight Junctions with No Sequence Similarity to Occludin

1998 1.7k citations Mikio Furuse, Shöichiro Tsukita et al. The Journal of Cell Biology profile →
Size-selective loosening of the blood-brain barrier in claudin-5–deficient mice

2003 1.4k citations Masaki Hata, Hiroyuki Sasaki et al. The Journal of Cell Biology profile →
Claudin-based tight junctions are crucial for the mammalian epidermal barrier

2002 1.2k citations Mikio Furuse, Masaki Hata et al. The Journal of Cell Biology profile →
Claudin multigene family encoding four-transmembrane domain protein components of tight junction strands

1999 941 citations Mikio Furuse, Shöichiro Tsukita et al. Proceedings of the National Academy of Sciences profile →
Complex Phenotype of Mice Lacking Occludin, a Component of Tight Junction Strands

2000 926 citations Mitinori Saitou, Mikio Furuse et al. profile →
Direct Binding of Three Tight Junction-Associated Maguks, Zo-1, Zo-2, and Zo-3, with the Cooh Termini of Claudins

1999 907 citations Masahiko Itoh, Mikio Furuse et al. The Journal of Cell Biology profile →
Direct association of occludin with ZO-1 and its possible involvement in the localization of occludin at tight junctions.

1994 797 citations Mikio Furuse, Masahiko Itoh et al. The Journal of Cell Biology profile →
A Single Gene Product, Claudin-1 or -2, Reconstitutes Tight Junction Strands and Recruits Occludin in Fibroblasts

1998 770 citations Mikio Furuse, Hiroyuki Sasaki et al. The Journal of Cell Biology profile →
Endothelial Claudin

1999 704 citations Hiroyuki Sasaki, Mikio Furuse et al. The Journal of Cell Biology profile →
ZO-1 and ZO-2 Independently Determine Where Claudins Are Polymerized in Tight-Junction Strand Formation

2006 654 citations Junichi Ikenouchi, Kyoko Furuse et al. profile →
Conversion of Zonulae Occludentes from Tight to Leaky Strand Type by Introducing Claudin-2 into Madin-Darby Canine Kidney I Cells

2001 611 citations Mikio Furuse, Kyoko Furuse et al. The Journal of Cell Biology profile →
Tricellulin constitutes a novel barrier at tricellular contacts of epithelial cells

2005 609 citations Junichi Ikenouchi, Mikio Furuse et al. The Journal of Cell Biology profile →
Manner of Interaction of Heterogeneous Claudin Species within and between Tight Junction Strands

1999 592 citations Mikio Furuse, Hiroyuki Sasaki et al. The Journal of Cell Biology profile →
Regulation of tight junctions during the epithelium-mesenchyme transition:direct repression of the gene expression of claudins/occludin by Snail

2003 553 citations Junichi Ikenouchi, Mikio Furuse et al. Journal of Cell Science profile →
Occludin is a functional component of the tight junction

1996 539 citations Mikio Furuse, Shöichiro Tsukita et al. Journal of Cell Science profile →
Occludin as a possible determinant of tight junction permeability in endothelial cells

1997 517 citations Mitinori Saitou, Masahiko Itoh et al. Journal of Cell Science profile →
Clostridium perfringens Enterotoxin Fragment Removes Specific Claudins from Tight Junction Strands

1999 509 citations Mikio Furuse, Hiroyuki Sasaki et al. The Journal of Cell Biology profile →
Tight Junction Structure and Function Revisited

2020 463 citations Tetsuhisa Otani, Mikio Furuse Trends in Cell Biology profile →

Peers

Countries citing papers authored by Mikio Furuse

Since Specialization

Citations

This map shows the geographic impact of Mikio Furuse's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Mikio Furuse with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Mikio Furuse more than expected).

Fields of papers citing papers by Mikio Furuse

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Mikio Furuse. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Mikio Furuse. The network helps show where Mikio Furuse may publish in the future.

Co-authorship network of co-authors of Mikio Furuse

This figure shows the co-authorship network connecting the top 25 collaborators of Mikio Furuse. A scholar is included among the top collaborators of Mikio Furuse based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Mikio Furuse. Mikio Furuse is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	Claudin-11 regulates immunological barrier formation and spermatogonial proliferation through stem cell factor 2025 ·Communications Biology ·T. Sugawara, (unknown), (unknown), Kazuhiro Noguchi, (unknown), Mikio Furuse, Tomohiko Wakayama	1
2	Bicellular Localization of Tricellular Junctional Protein Angulin-3/ILDR2 Allows Detection of Podocyte Injury 2024 ·American Journal Of Pathology ·Atsuko Y. Higashi, Akira Saitō, Tomohito Higashi, (unknown), Mikio Furuse, Hideki Chiba, Junichiro James Kazama	1
3	Tight junction membrane proteins regulate the mechanical resistance of the apical junctional complex 2024 ·The Journal of Cell Biology ·(unknown), Tetsuhisa Otani, Motosuke Tsutsumi, Noriyuki Kinoshita, Sachiko Fujiwara, Tomomi Nemoto, Toshihiko Fujimori, Mikio Furuse	13
4	Mechanism of interdigitation formation at apical boundary of MDCK cell 2023 ·iScience ·(unknown), Tetsuhisa Otani, Kei Sugihara, Toshihiko Fujimori, Mikio Furuse, Takashi Miura	3
5	Nanoscale segregation of channel and barrier claudins enables paracellular ion flux 2022 ·Nature Communications ·(unknown), Christopher Schmied, (unknown), Jenny Eichhorst, Nina Himmerkus, Jörg Piontek, Dorothee Günzel, Markus Bleich, Mikio Furuse, Volker Haucke, Martin Lehmann	44
6	The novel membrane protein Hoka regulates septate junction organization and stem cell homeostasis in the Drosophila gut 2021 ·Journal of Cell Science ·Yasushi Izumi, Kyoko Furuse, Mikio Furuse	8
7	Septate junctions regulate gut homeostasis through regulation of stem cell proliferation and enterocyte behavior in Drosophila 2019 ·Journal of Cell Science ·Yasushi Izumi, Kyoko Furuse, Mikio Furuse	29
8	Claudins and JAM-A coordinately regulate tight junction formation and epithelial polarity 2019 ·The Journal of Cell Biology ·Tetsuhisa Otani, (unknown), Shinsaku Tokuda, Kei Sugihara, T. Sugawara, Kyoko Furuse, Takashi Miura, Klaus Ebnet, Mikio Furuse	161
9	Ripply3 is required for the maintenance of epithelial sheets in the morphogenesis of pharyngeal pouches 2018 ·Development Growth & Differentiation ·(unknown), Yusuke Mii, Kazunori Okada, Mikio Furuse, Tadashi Okubo, Shinji Takada	4
10	Epidermal tight junction barrier function is altered by skin inflammation, but not by filaggrin-deficient stratum corneum 2014 ·Journal of Dermatological Science ·Mariko Yokouchi, Akiharu Kubo, Hiroshi Kawasaki, Kazue Yoshida, Ken Ishii, Mikio Furuse, Masayuki Amagai	76
11	Contribution of Tight Junction Proteins to Ion, Macromolecule, and Water Barrier in Keratinocytes 2013 ·Journal of Investigative Dermatology ·Nina Kirschner, Rita Rosenthal, Mikio Furuse, Ingrid Moll, Michael Fromm, Johanna M. Brandner	138
12	LSR defines cell corners for tricellular tight junction formation in epithelial cells 2011 ·Journal of Cell Science ·Sayuri Masuda, Yukako Oda, Hiroyuki Sasaki, Junichi Ikenouchi, Tomohito Higashi, Masaya Akashi, Eiichiro Nishi, Mikio Furuse	198
13	Claudins and renal salt transport 2011 ·Clinical and Experimental Nephrology ·Shigeaki Muto, Mikio Furuse, Eiji Kusano	24
14	Claudin-2–deficient mice are defective in the leaky and cation-selective paracellular permeability properties of renal proximal tubules 2010 ·Proceedings of the National Academy of Sciences ·Shigeaki Muto, Masaki Hata, Junichi Taniguchi, Shuichi Tsuruoka, Kazumasa Moriwaki, Mitinori Saitou, Kyoko Furuse, Hiroyuki Sasaki, Akio Fujimura, Masashi Imai, Eiji Kusano, Shöichiro Tsukita, Mikio Furuse	228
15	CD44 Regulates Tight-Junction Assembly and Barrier Function 2010 ·Journal of Investigative Dermatology ·Nina Kirschner, Marek Haftek, Carien M. Niessen, Martin J. Behne, Mikio Furuse, Ingrid Moll, Johanna M. Brandner	63
16	Dynamic behavior of paired claudin strands within apposing plasma membranes 2003 ·Proceedings of the National Academy of Sciences ·Hiroyuki Sasaki, Chiyuki Matsui, Kyoko Furuse, Yuko Mimori‐Kiyosue, Mikio Furuse, Shöichiro Tsukita	191
17	Overexpression of Interferon α/β Receptor β Chain in Fetal Down Syndrome Brain 2003 ·Rosa Ferrando-Miguel, Ki‐Shuk Shim, Myeong Sook Cheon, Mario Gimona, Mikio Furuse, Gert Lübec	8
18	Multifunctional strands in tight junctions breakdown → 2001 ·Nature Reviews Molecular Cell Biology ·Shöichiro Tsukita, Mikio Furuse, Masahiko Itoh	2054
19	Occludin and claudins in tight-junction strands: leading or supporting players? 1999 ·Trends in Cell Biology ·(unknown), (unknown), Mikio Furuse	493
20	Strong induction of ICAM‐1 in human T cells transformed by human T‐cell‐leukemia virus type 1 and depression of ICAM‐1 or LFA‐1 in adult T‐cell‐leukemia‐derived cell lines 1992 ·International Journal of Cancer ·Kenji Fukudome, Mikio Furuse, Norio Fukuhara, Satoshi Orita, Toshio Imai, Shin Takagi, Morio Nagira, Yorio Hinuma, Osamu Yoshie	64

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact