Jakub Tolar

16.9k citations

270 papers · 10.1k indexed · 4 hit papers · h-index 52

Hematology top 0.5%
- Hematopoietic Stem Cell Transplantation 41
Genetics top 0.5%
- Virus-based gene therapy research 24
- Mesenchymal stem cell research 21
Immunology top 1%
- Immune Cell Function and Interaction 21
Cell Biology top 0.5%
- Skin and Cellular Biology Research 48
Oncology top 1%
Physiology
- Lysosomal Storage Disorders Research 34
Molecular Biology
- CRISPR and Genetic Engineering 31
- Pluripotent Stem Cells Research 22

Co-authors: Bruce R. Blazar Paul J. Orchard Mark J. Osborn John E. Wagner Troy C. Lund Megan Riddle Steven L. Teitelbaum Ron McElmurry
Cited by: Hematology Genetics Immunology
Partner nations: United States United Kingdom Canada

In The Last Decade

Jakub Tolar

259 papers receiving 9.9k citations

Hit Papers

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What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

2024 Efficient site-specific integration of large genes in mammalian cells via continuously evolved recombinases and prime editing
2023 Phage-assisted evolution and protein engineering yield compact, efficient prime editors
2022 Evolution of an adenine base editor into a small, efficient cytosine base editor with low off-target activity
2020 Advanced reperfusion strategies for patients with out-of-hospital cardiac arrest and refractory ventricular fibrillation (ARREST): a phase 2, single centre, open-label, randomised controlled trial

Peers

Countries citing papers authored by Jakub Tolar

Since Specialization

Citations

This map shows the geographic impact of Jakub Tolar's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jakub Tolar with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jakub Tolar more than expected).

Fields of papers citing papers by Jakub Tolar

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jakub Tolar. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jakub Tolar. The network helps show where Jakub Tolar may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Jakub Tolar, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Jakub Tolar Line = papers co-authored together Jakub Tolar links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Deficiency of T follicular helper cell Tet3 DNA demethylation inhibits pathogenic IgG2c class switching and chronic GVHD Michael Zaiken,Sujeong Jin,Cameron McDonald-Hyman,Christina R. Hartigan,Peter T. Sage,Keli L. Hippen,Brent H. Koehn,Angela Panoskaltsis‐Mortari,Megan Riddle,Cindy Eide,Jakub Tolar,Geoffrey R. Hill,Leo Luznik,Corey Cutler,Jerome Ritz,Leslie S. Kean,Ageliki Tsagaratou,Anjana Rao,Bruce R. Blazar	2025	1
2	Chondroitin sulfate proteoglycan 4 increases invasion of recessive dystrophic epidermolysis bullosa-associated cutaneous squamous cell carcinoma by modifying transforming growth factor-β signalling A. Macaulay,Jianbo Yang,Matt A. Price,Colleen L. Forster,Megan Riddle,Christen L. Ebens,Frank W. Albert,Alessio Giubellino,James B. McCarthy,Jakub Tolar	2024	1
3	Twin Prime Editing Mediated Exon Skipping/Reinsertion for Restored Collagen VII Expression in Recessive Dystrophic Epidermolysis Bullosa Benjamin J. Steinbeck,Xin D. Gao,Amber McElroy,Smriti Pandey,Jordan L. Doman,Megan Riddle,Lily Xia,Weili Chen,Cindy Eide,André van Helvoort Lengert,Sang Won Han,Bruce R. Blazar,Hans H. Wandall,Sally Dabelsteen,David R. Liu,Jakub Tolar,Mark J. Osborn	2024	5
4	Beyond the Surface: A Narrative Review Examining the Systemic Impacts of Recessive Dystrophic Epidermolysis Bullosa Courtney Popp,William Miller,Cindy Eide,Jakub Tolar,John A. McGrath,Christen L. Ebens	2024	6
5	Accelerated Aging and Microsatellite Instability in Recessive Dystrophic Epidermolysis Bullosa–Associated Cutaneous Squamous Cell Carcinoma Catherine Lee,Siyuan Wu,Yuen Ting Chow,Eric Kofman,Valencia Williams,Megan Riddle,Cindy Eide,Christen L. Ebens,Markus H. Frank,Jakub Tolar,Kristen P. Hook,Saud H. AlDubayan,Natasha Y. Frank	2024	1
6	Allogeneic Hematopoietic Cell Transplant For Bone Marrow Failure or Myelodysplastic Syndrome in Dyskeratosis Congenita/Telomere Biology Disorders: Single-Center, Single-Arm, Open-Label Trial of Reduced-Intensity Conditioning Without Radiation Marketa Dimitrov,Svatava Merkle,Qing Cao,Rebecca Tryon,Gregory M. Vercellotti,Shernan G. Holtan,Roy L. Kao,Meera Srikanthan,Stephanie A. Terezakis,Jakub Tolar,Christen L. Ebens	2024	0
7	ABCB5+ mesenchymal stromal cells facilitate complete and durable wound closure in recessive dystrophic epidermolysis bullosa Kathrin Dieter,Elke Niebergall‐Roth,Cristina Daniele,Silvia Fluhr,Natasha Y. Frank,Christoph Ganss,Dimitra Kiritsi,John A. McGrath,Jakub Tolar,Markus H. Frank,Mark A. Kluth	2023	10
8	Engineering CRISPR/Cas9 for Multiplexed Recombinant Coagulation Factor Production Colby J. Feser,Christopher J. Lees,Daniel Lammers,Megan Riddle,Jason Bingham,Matthew J. Eckert,Jakub Tolar,Mark J. Osborn	2022	1
9	Immune tolerance of allogeneic haematopoietic cell transplantation supports donor epidermal grafting of recessive dystrophic epidermolysis bullosa chronic wounds* Christen L. Ebens,John A. McGrath,Julia Riedl,Allison Keith,G. Lilja,S. Rusch,Douglas R. Keene,Sara F. Tufa,Megan Riddle,Ryan Shanley,Ann E. Van Heest,Jakub Tolar	2020	13
10	Leading edge: emerging drug, cell, and gene therapies for junctional epidermolysis bullosa Allison Keith,Kirk Twaroski,Christen L. Ebens,Jakub Tolar	2020	15
11	Base Editor Correction of COL7A1 in Recessive Dystrophic Epidermolysis Bullosa Patient-Derived Fibroblasts and iPSCs Mark J. Osborn,Gregory A. Newby,Amber McElroy,Friederike Knipping,Sarah C. Nielsen,Megan Riddle,Lily Xia,Weili Chen,Cindy Eide,Beau R. Webber,Hans H. Wandall,Sally Dabelsteen,Bruce R. Blazar,David R. Liu,Jakub Tolar	2019	75
12	Block Polymer Micelles Enable CRISPR/Cas9 Ribonucleoprotein Delivery: Physicochemical Properties Affect Packaging Mechanisms and Gene Editing Efficiency Zhe Tan,Yaming Jiang,Mitra S. Ganewatta,Ramya Kumar,Allison Keith,Kirk Twaroski,Thomas Pengo,Jakub Tolar,Timothy P. Lodge,Theresa M. Reineke	2019	51
13	A multitask clustering approach for single-cell RNA-seq analysis in Recessive Dystrophic Epidermolysis Bullosa Teng Zhang,Catherine Lee,Zhuliu Li,John Garbe,Cindy Eide,Raphael Petegrosso,Rui Kuang,Jakub Tolar	2018	24
14	IL15 Trispecific Killer Engagers (TriKE) Make Natural Killer Cells Specific to CD33+ Targets While Also Inducing Persistence, In Vivo Expansion, and Enhanced Function Daniel A. Vallera,Martin Felices,Ron McElmurry,Valarie McCullar,Xianzheng Zhou,Joerg Uwe Schmohl,Bin Zhang,Alexander J. Lenvik,Angela Panoskaltsis‐Mortari,Michael R. Verneris,Jakub Tolar,Sarah Cooley,Daniel J. Weisdorf,Bruce R. Blazar,Jeffrey S. Miller	2016	295
15	DNA methylation of Runx1 regulatory regions correlates with transition from primitive to definitive hematopoietic potential in vitro and in vivo Beau R. Webber,Michelina Iacovino,Si Ho Choi,Jakub Tolar,Michael Kyba,Bruce R. Blazar	2013	16
16	Program death-1 signaling and regulatory T cells collaborate to resist the function of adoptively transferred cytotoxic T lymphocytes in advanced acute myeloid leukemia Qing Zhou,Meghan E. Munger,Steven L. Highfill,Jakub Tolar,Brenda J. Weigel,Megan Riddle,Arlene H. Sharpe,Daniel A. Vallera,Miyuki Azuma,Bruce L. Levine,Carl H. June,William J. Murphy,David H. Munn,Bruce R. Blazar	2010	230
17	Cross-genome knowledge-based expression data fusion Matěj Holec,Jǐŕı Kléma,Filip Železný,Jiří Bělohradský,Jakub Tolar	2009	2
18	Adult stem cells for treatment of Recessive Dystrophic Epidermolysis Bullosa (RDEB) Jasenka Wagner,Akemi Ishida‐Yamamoto,John A. McGrath,Douglas R. Keene,Maria Hordinsky,Bruce R. Blazar,Jakub Tolar	2009	4
19	Amelioration of epidermolysis bullosa by transfer of wild-type bone marrow cells Jakub Tolar,Akemi Ishida‐Yamamoto,Megan Riddle,Ron McElmurry,Mark J. Osborn,Lily Xia,Troy C. Lund,Catherine F. Slattery,Jouni Uitto,Angela M. Christiano,John E. Wagner,Bruce R. Blazar	2008	125
20	Hematopoietic reconstitution by multipotent adult progenitor cells: precursors to long-term hematopoietic stem cells Marta Serafini,Scott J. Dylla,Masayuki Oki,Yves Heremans,Jakub Tolar,Yuehua Jiang,Suzanne M. K. Buckley,Beatriz Pelacho,Terry C. Burns,Sarah A. Frommer,Derrick J. Rossi,David Bryder,Angela Panoskaltsis‐Mortari,Matthew J. O’Shaughnessy,Molly Nelson-Holte,G Fine,Irving L. Weissman,Bruce R. Blazar,Catherine M. Verfaillie	2007	75

About Jakub Tolar

Jakub Tolar is a scholar working on Hematology, Genetics and Cell Biology, having authored 270 papers that have together received 10.1k indexed citations. Recurring topics across this work include Skin and Cellular Biology Research (48 papers), Hematopoietic Stem Cell Transplantation (41 papers), Lysosomal Storage Disorders Research (34 papers), CRISPR and Genetic Engineering (31 papers), Virus-based gene therapy research (24 papers), Pluripotent Stem Cells Research (22 papers), Immune Cell Function and Interaction (21 papers) and Mesenchymal stem cell research (21 papers). The work is most often cited by research in Hematology (1.5k citations), Genetics (1.2k citations) and Immunology (2.0k citations). Jakub Tolar has collaborated with scholars based in United States, United Kingdom and Canada. Frequent co-authors include Bruce R. Blazar, Paul J. Orchard, Mark J. Osborn, John E. Wagner, Troy C. Lund, Megan Riddle, Steven L. Teitelbaum, Ron McElmurry, Angela Panoskaltsis‐Mortari and Armand Keating.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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