Eelke B. Lenselink

1.8k citations

37 papers · 1.3k indexed · h-index 19

Molecular Biology top 10%
Computational Theory and Mathematics top 1%
Materials Chemistry
Cellular and Molecular Neuroscience top 10%
Organic Chemistry top 10%

Co-authors: Adriaan P. IJzerman Herman van Vlijmen Gerard J. P. van Westen Laura H. Heitman George Papadatos Brandon J. Bongers Wojtek Kowalczyk Thijs Beuming
Topics: Receptor Mechanisms and Signaling (18 papers)Computational Drug Discovery Methods (12 papers)Adenosine and Purinergic Signaling (10 papers)
Cited by: Computational Theory and Mathematics Physiology Molecular Biology
Journals: Nature Communications The FASEB Journal Journal of Medicinal Chemistry
Partner nations: Netherlands United States United Kingdom

In The Last Decade

Eelke B. Lenselink

37 papers receiving 1.2k citations

Peers

Countries citing papers authored by Eelke B. Lenselink

Since Specialization

Citations

This map shows the geographic impact of Eelke B. Lenselink's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Eelke B. Lenselink with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Eelke B. Lenselink more than expected).

Fields of papers citing papers by Eelke B. Lenselink

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Eelke B. Lenselink. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Eelke B. Lenselink. The network helps show where Eelke B. Lenselink may publish in the future.

Co-authorship network of co-authors of Eelke B. Lenselink

This figure shows the co-authorship network connecting the top 25 collaborators of Eelke B. Lenselink. A scholar is included among the top collaborators of Eelke B. Lenselink based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Eelke B. Lenselink. Eelke B. Lenselink is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Large-Scale Modeling of Sparse Protein Kinase Activity Data 2023 ·Journal of Chemical Information and Modeling ·(unknown),Erik Meijer,(unknown),(unknown),Pieter F. W. Stouten,Gerard J. P. van Westen,Eelke B. Lenselink	7
2	Enhancing Hit Discovery in Virtual Screening through Absolute Protein–Ligand Binding Free-Energy Calculations 2023 ·Journal of Chemical Information and Modeling ·Wei Chen,(unknown),Steven V. Jerome,Mayako Michino,Eelke B. Lenselink,David J. Huggins,Alexandre Beautrait,Jérémie Vendôme,Robert Abel,Richard A. Friesner,Lingle Wang	69
3	Multitask machine learning models for predicting lipophilicity (logP) in the SAMPL7 challenge 2021 ·Journal of Computer-Aided Molecular Design ·Eelke B. Lenselink,Pieter F. W. Stouten	17
4	Chemical genetics strategy to profile kinase target engagement reveals role of FES in neutrophil phagocytosis 2020 ·Nature Communications ·Tom van der Wel,Riet Hilhorst,Hans den Dulk,(unknown),(unknown),(unknown),Bogdan I. Florea,Eelke B. Lenselink,Gerard J. P. van Westen,Rob Ruijtenbeek,Herman S. Overkleeft,Allard Kaptein,Tjeerd Barf,Mario van der Stelt	9
5	Comprehensive structure-activity-relationship of azaindoles as highly potent FLT3 inhibitors 2019 ·Bioorganic & Medicinal Chemistry ·(unknown),(unknown),(unknown),(unknown),Ruud H. Wijdeven,Eelke B. Lenselink,Adriaan W. Tuin,Adrianus M. C. H. van den Nieuwendijk,Gerard J. P. van Westen,C. A. A. VAN BOECKEL,Herman S. Overkleeft,Jacques Neefjes,Mario van der Stelt	6
6	Synthesis and Pharmacological Evaluation of Triazolopyrimidinone Derivatives as Noncompetitive, Intracellular Antagonists for CC Chemokine Receptors 2 and 5 2019 ·Journal of Medicinal Chemistry ·Natalia V. Ortiz Zacarı́as,Jacobus P. D. van Veldhoven,(unknown),(unknown),(unknown),(unknown),Eelke B. Lenselink,Laura H. Heitman,Adriaan P. IJzerman	13
7	Drug Discovery Maps, a Machine Learning Model That Visualizes and Predicts Kinome–Inhibitor Interaction Landscapes 2018 ·Journal of Chemical Information and Modeling ·Antonius P. A. Janssen,(unknown),Ruud H. Wijdeven,Eelke B. Lenselink,Jacques Neefjes,C. A. A. VAN BOECKEL,Gerard J. P. van Westen,Mario van der Stelt	54
8	Intracellular Receptor Modulation: Novel Approach to Target GPCRs 2018 ·Trends in Pharmacological Sciences ·Natalia V. Ortiz Zacarı́as,Eelke B. Lenselink,Adriaan P. IJzerman,Tracy M. Handel,Laura H. Heitman	49
9	Kinetics of human cannabinoid 1 (CB1) receptor antagonists: Structure-kinetics relationships (SKR) and implications for insurmountable antagonism 2017 ·Biochemical Pharmacology ·Lizi Xia,Henk de Vries,Xue Yang,Eelke B. Lenselink,(unknown),Francis Barth,Julien Louvel,Matthias Dreyer,Daan van der Es,Adriaan P. IJzerman,Laura H. Heitman	10
10	Beyond the hype: deep neural networks outperform established methods using a ChEMBL bioactivity benchmark set 2017 ·Journal of Cheminformatics ·Eelke B. Lenselink,(unknown),Brandon J. Bongers,George Papadatos,Herman van Vlijmen,Wojtek Kowalczyk,Adriaan P. IJzerman,Gerard J. P. van Westen	216
11	In search of novel ligands using a structure-based approach: a case study on the adenosine A2A receptor 2016 ·Journal of Computer-Aided Molecular Design ·Eelke B. Lenselink,Thijs Beuming,(unknown),Arnault Massink,Woody Sherman,Herman van Vlijmen,Adriaan P. IJzerman	18
12	A covalent antagonist for the human adenosine A2A receptor 2016 ·Purinergic Signalling ·Xue Yang,(unknown),(unknown),Eelke B. Lenselink,Laura H. Heitman,Julien Louvel,Adriaan P. IJzerman	20
13	Synthesis and evaluation of N-substituted 2-amino-4,5-diarylpyrimidines as selective adenosine A1 receptor antagonists 2016 ·European Journal of Medicinal Chemistry ·Georgios Alachouzos,Eelke B. Lenselink,Thea Mulder‐Krieger,Henk de Vries,Adriaan P. IJzerman,Julien Louvel	11
14	5′-Substituted Amiloride Derivatives as Allosteric Modulators Binding in the Sodium Ion Pocket of the Adenosine A_2AReceptor 2016 ·Journal of Medicinal Chemistry ·Arnault Massink,Julien Louvel,(unknown),(unknown),(unknown),Gabrielle S. Dijksteel,Dong Guo,Eelke B. Lenselink,Benjamin J. Buckley,Hayden Matthews,Marie Ranson,Michael J. Kelso,Adriaan P. IJzerman	26
15	Scanning mutagenesis in a yeast system delineates the role of the NPxxY(x) 5,6 F motif and helix 8 of the adenosine A 2B receptor in G protein coupling 2015 ·Biochemical Pharmacology ·(unknown),(unknown),(unknown),Eelke B. Lenselink,Adriaan P. IJzerman	16
16	Sodium Ion Binding Pocket Mutations and Adenosine A2A Receptor Function 2014 ·Molecular Pharmacology ·Arnault Massink,Hugo Gutiérrez‐de‐Terán,Eelke B. Lenselink,Natalia V. Ortiz Zacarı́as,Lizi Xia,Laura H. Heitman,Vsevolod Katritch,Raymond C. Stevens,Adriaan P. IJzerman	75
17	Discovery and Mapping of an Intracellular Antagonist Binding Site at the Chemokine Receptor CCR2 2014 ·Molecular Pharmacology ·Annelien J.M. Zweemer,(unknown),(unknown),Fabiana Miraglia,Eelke B. Lenselink,(unknown),Henk de Vries,(unknown),Stefanie Thiele,Mette M. Rosenkilde,Adriaan P. IJzerman,Laura H. Heitman	42
18	Domains for activation and inactivation in G protein-coupled receptors – A mutational analysis of constitutive activity of the adenosine A2B receptor 2014 ·Biochemical Pharmacology ·Miriam C. Peeters,Qilan Li,(unknown),Gerard J. P. van Westen,Eelke B. Lenselink,Christa E. Müller,Adriaan P. IJzerman	9
19	Proteochemometric modeling in a Bayesian framework 2014 ·Journal of Cheminformatics ·Isidro Cortés‐Ciriano,Gerard J. P. van Westen,Eelke B. Lenselink,(unknown),Andreas Bender,Thérèse E. Malliavin	33
20	A yeast screening method to decipher the interaction between the adenosine A2B receptor and the C-terminus of different G protein α-subunits 2014 ·Purinergic Signalling ·(unknown),(unknown),Miriam C. Peeters,Eelke B. Lenselink,Adriaan P. IJzerman	15

About Eelke B. Lenselink

Eelke B. Lenselink is a scholar working on Physiology, Computational Theory and Mathematics and Cellular and Molecular Neuroscience, having authored 37 papers that have together received 1.3k indexed citations. Recurring topics across this work include Receptor Mechanisms and Signaling (18 papers), Computational Drug Discovery Methods (12 papers) and Adenosine and Purinergic Signaling (10 papers). The work is most often cited by research in Computational Theory and Mathematics (585 citations), Physiology (116 citations) and Molecular Biology (963 citations). Eelke B. Lenselink has collaborated with scholars based in Netherlands, United States and United Kingdom. Frequent co-authors include Adriaan P. IJzerman, Herman van Vlijmen, Gerard J. P. van Westen, Laura H. Heitman, George Papadatos, Brandon J. Bongers, Wojtek Kowalczyk, Thijs Beuming, Woody Sherman and Julien Louvel. Their work appears in journals such as Nature Communications, The FASEB Journal and Journal of Medicinal Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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