David C. Rees

4.0k total citations · 2 hit papers
16 papers, 3.1k citations indexed

About

David C. Rees is a scholar working on Organic Chemistry, Molecular Biology and Computational Theory and Mathematics. According to data from OpenAlex, David C. Rees has authored 16 papers receiving a total of 3.1k indexed citations (citations by other indexed papers that have themselves been cited), including 9 papers in Organic Chemistry, 6 papers in Molecular Biology and 6 papers in Computational Theory and Mathematics. Recurrent topics in David C. Rees's work include Computational Drug Discovery Methods (6 papers), Chemical Synthesis and Analysis (5 papers) and Click Chemistry and Applications (4 papers). David C. Rees is often cited by papers focused on Computational Drug Discovery Methods (6 papers), Chemical Synthesis and Analysis (5 papers) and Click Chemistry and Applications (4 papers). David C. Rees collaborates with scholars based in United Kingdom, Netherlands and Switzerland. David C. Rees's co-authors include Christopher W. Murray, Andrew W. Thomas, Luis C. Misal Castro, David M. Wilson, Anthony Wood, Ian Churcher, David C. Blakemore, Robin A. E. Carr, Miles Congreve and Ronald Palin and has published in prestigious journals such as Angewandte Chemie International Edition, Nature Reviews Drug Discovery and Nature Chemistry.

In The Last Decade

David C. Rees

15 papers receiving 3.0k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Organic synthesis provides opportunities to transform drug discovery

2018 1.2k citations David C. Blakemore, Luis C. Misal Castro et al. Nature Chemistry profile →
Fragment-based lead discovery

2004 567 citations David C. Rees, Miles Congreve et al. Nature Reviews Drug Discovery profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
David C. Rees United Kingdom	15	1.5k	1.2k	507	398	311	16	3.1k
Ming‐Qiang Zhang Netherlands	17	443 0.3×	590 0.5×	184 0.4×	402 1.0×	121 0.4×	45	1.7k
John J. Talley United States	25	1.8k 1.2×	571 0.5×	177 0.3×	30 0.1×	59 0.2×	43	3.1k
Rebecca M. Wilson United States	24	1.5k 1.0×	1.1k 0.9×	23 0.0×	38 0.1×	83 0.3×	33	2.3k
Fábio C. Tucci United States	29	1.1k 0.7×	529 0.4×	25 0.0×	27 0.1×	167 0.5×	101	2.6k
Manjunath S. Shet United States	21	197 0.1×	561 0.5×	131 0.3×	50 0.1×	515 1.7×	47	1.8k
Xiaomei Zhuang China	20	188 0.1×	534 0.5×	90 0.2×	12 0.0×	118 0.4×	96	1.6k
Andreas Link Germany	24	813 0.5×	1.4k 1.2×	136 0.3×	7 0.0×	105 0.3×	121	2.3k
Christine Luong United States	16	387 0.3×	549 0.5×	145 0.3×	18 0.0×	65 0.2×	19	1.5k
Hanna Kumpulainen Finland	5	305 0.2×	601 0.5×	84 0.2×	12 0.0×	131 0.4×	8	1.3k

Countries citing papers authored by David C. Rees

Since Specialization

Citations

This map shows the geographic impact of David C. Rees's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David C. Rees with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David C. Rees more than expected).

Fields of papers citing papers by David C. Rees

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David C. Rees. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David C. Rees. The network helps show where David C. Rees may publish in the future.

Co-authorship network of co-authors of David C. Rees

This figure shows the co-authorship network connecting the top 25 collaborators of David C. Rees. A scholar is included among the top collaborators of David C. Rees based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with David C. Rees. David C. Rees is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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16 of 16 papers shown

1.

Chessari, Gianni, et al.. (2021). C–H functionalisation tolerant to polar groups could transform fragment-based drug discovery (FBDD). Chemical Science. 12(36). 11976–11985. 20 indexed citations

2.

Denis, Jeffrey D. St., Richard J. Hall, Christopher W. Murray, Tom D. Heightman, & David C. Rees. (2020). Fragment-based drug discovery: opportunities for organic synthesis. RSC Medicinal Chemistry. 12(3). 321–329. 50 indexed citations

3.

Blakemore, David C., Luis C. Misal Castro, Ian Churcher, et al.. (2018). Organic synthesis provides opportunities to transform drug discovery. Nature Chemistry. 10(4). 383–394. 1152 indexed citations breakdown →

4.

Johnson, Christopher N., Daniel A. Erlanson, Wolfgang Jahnke, Paul N. Mortenson, & David C. Rees. (2017). Fragment-to-Lead Medicinal Chemistry Publications in 2016. Journal of Medicinal Chemistry. 61(5). 1774–1784. 42 indexed citations

5.

Johnson, Christopher N., Daniel A. Erlanson, Christopher W. Murray, & David C. Rees. (2016). Fragment-to-Lead Medicinal Chemistry Publications in 2015. Journal of Medicinal Chemistry. 60(1). 89–99. 52 indexed citations

6.

Murray, Christopher W. & David C. Rees. (2015). Organische Chemie für die fragmentbasierte Wirkstoffentwicklung (FBDD). Angewandte Chemie. 128(2). 498–503. 33 indexed citations

7.

Murray, Christopher W. & David C. Rees. (2015). Opportunity Knocks: Organic Chemistry for Fragment‐Based Drug Discovery (FBDD). Angewandte Chemie International Edition. 55(2). 488–492. 151 indexed citations

8.

Murray, Christopher W., Marcel L. Verdonk, & David C. Rees. (2012). Experiences in fragment-based drug discovery. Trends in Pharmacological Sciences. 33(5). 224–232. 179 indexed citations

9.

Rees, David C., Miles Congreve, Christopher W. Murray, & Robin A. E. Carr. (2004). Fragment-based lead discovery. Nature Reviews Drug Discovery. 3(8). 660–672. 567 indexed citations breakdown →

10.

Bom, A., Mark Philip Bradley, John K. Clark, et al.. (2002). A Novel Concept of Reversing Neuromuscular Block: Chemical Encapsulation of Rocuronium Bromide by a Cyclodextrin-Based Synthetic Host The discovery of Org 25969 is the result of teamwork with contributions from a number of scientists both inside Organon and outside the company. We would like in particular to acknowledge the following scientists for their invaluable contributions: E. Hutchinson, D. Stevenson, R. Roy, and J. Pick for scaling-up the synthesis; F. Hope, S. Miller, and R. Mason for various in vitro and in vivo pharmacological testing; R. Watson, B. Montgomery, P. Desmond, and A. Osprey for all their analytical effort; and R. McGuire and J. Mestres for graphical presentation of the X-ray crystal structure of the Org 25969–rocuronium complex (Figure 3). We would also like to thank Prof. A. Cooper of Glasgow University who has critically reproduced our calorimetry data of Org 25969–rocuronium complexation (Figure 2).. Angewandte Chemie International Edition. 41(2). 265–265. 375 indexed citations

11.

Fielding, Lee A., et al.. (2002). Anionic Cyclophanes as Potential Reversal Agents of Muscle Relaxants by Chemical Chelation. Bioorganic & Medicinal Chemistry Letters. 12(5). 753–755. 17 indexed citations

12.

Bom, A., Mark Philip Bradley, John K. Clark, et al.. (2002). A Novel Concept of Reversing Neuromuscular Block: Chemical Encapsulation of Rocuronium Bromide by a Cyclodextrin-Based Synthetic Host. Angewandte Chemie. 114(2). 275–280. 173 indexed citations

13.

Adam, Julia M., David Jonathan Bennett, A. Bom, et al.. (2002). Cyclodextrin-Derived Host Molecules as Reversal Agents for the Neuromuscular Blocker Rocuronium Bromide: Synthesis and Structure−Activity Relationships. Journal of Medicinal Chemistry. 45(9). 1806–1816. 190 indexed citations

14.

Hall, Adrian, Patrick D. Bailey, David C. Rees, Georgina M. Rosair, & R. H. WIGHTMAN. (2000). α-Chloronitroso compounds derived from carbohydrate ketones: cycloadditions with cyclic dienes, a synthesis of (−)-physoperuvine and a formal synthesis of (+)-epibatidine. Journal of the Chemical Society Perkin Transactions 1. 329–342. 29 indexed citations

15.

Rees, David C., et al.. (1999). A review of recent applications of cyclodextrins for drug discovery. Expert Opinion on Therapeutic Patents. 9(12). 1697–1717. 31 indexed citations

16.

Behringer, Elizabeth C., et al.. (1991). Poorly performed lung function tests--the answer is not blowing in the wind.. PubMed. 80(7). 313–4.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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