David C. Rees

4.0k citations

16 papers · 3.1k indexed · 2 hit papers · h-index 15

Anesthesiology and Pain Medicine top 1%
Organic Chemistry top 1%
- Click Chemistry and Applications 4
- Catalytic C–H Functionalization Methods 2
- Synthesis and Catalytic Reactions 2
Developmental Neuroscience top 2%
- Anesthesia and Neurotoxicity Research 2
Pharmaceutical Science top 2%
Computational Theory and Mathematics top 1%
- Computational Drug Discovery Methods 6
Molecular Biology
- Chemical Synthesis and Analysis 5
Pharmacology
- Microbial Natural Products and Biosynthesis 2
Economics and Econometrics
- Pharmaceutical Economics and Policy 2

Co-authors: Christopher W. Murray Andrew W. Thomas Luis C. Misal Castro David M. Wilson Anthony Wood Ian Churcher David C. Blakemore Robin A. E. Carr
Cited by: Anesthesiology and Pain Medicine Organic Chemistry Developmental Neuroscience
Journals: Journal of Medicinal Chemistry (3 papers)Angewandte Chemie International Edition (2 papers)Nature Chemistry (1 paper)
Partner nations: United Kingdom Netherlands Switzerland

In The Last Decade

David C. Rees

15 papers receiving 3.0k citations

Hit Papers

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Peers

Countries citing papers authored by David C. Rees

Since Specialization

Citations

This map shows the geographic impact of David C. Rees's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David C. Rees with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David C. Rees more than expected).

Fields of papers citing papers by David C. Rees

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David C. Rees. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David C. Rees. The network helps show where David C. Rees may publish in the future.

Co-authorship network

The 25 scholars most cited alongside David C. Rees, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with David C. Rees Line = papers co-authored together David C. Rees links everyone, so they are left out of the graph.

All Works

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16 of 16 papers shown

#	Work
1	C–H functionalisation tolerant to polar groups could transform fragment-based drug discovery (FBDD) Chemical Science ·Gianni Chessari,Rachel Grainger,王宓,R. Frederick Ludlow,Paul N. Mortenson,David C. Rees	2021	20
2	Fragment-based drug discovery: opportunities for organic synthesis RSC Medicinal Chemistry ·Jeffrey D. St. Denis,Richard J. Hall,Christopher W. Murray,Tom D. Heightman,David C. Rees	2020	50
3	Organic synthesis provides opportunities to transform drug discoverybreakdown → Nature Chemistry ·David C. Blakemore,Luis C. Misal Castro,Ian Churcher,David C. Rees,Andrew W. Thomas,David M. Wilson,Anthony Wood	2018	1152
4	Fragment-to-Lead Medicinal Chemistry Publications in 2016 Journal of Medicinal Chemistry ·Christopher N. Johnson,Daniel A. Erlanson,Wolfgang Jahnke,Paul N. Mortenson,David C. Rees	2017	42
5	Fragment-to-Lead Medicinal Chemistry Publications in 2015 Journal of Medicinal Chemistry ·Christopher N. Johnson,Daniel A. Erlanson,Christopher W. Murray,David C. Rees	2016	52
6	Organische Chemie für die fragmentbasierte Wirkstoffentwicklung (FBDD) Angewandte Chemie ·Christopher W. Murray,David C. Rees	2015	33
7	Opportunity Knocks: Organic Chemistry for Fragment‐Based Drug Discovery (FBDD) Angewandte Chemie International Edition ·Christopher W. Murray,David C. Rees	2015	151
8	Experiences in fragment-based drug discovery Trends in Pharmacological Sciences ·Christopher W. Murray,Marcel L. Verdonk,David C. Rees	2012	179
9	Fragment-based lead discoverybreakdown → Nature Reviews Drug Discovery ·David C. Rees,Miles Congreve,Christopher W. Murray,Robin A. E. Carr	2004	567
10	A Novel Concept of Reversing Neuromuscular Block: Chemical Encapsulation of Rocuronium Bromide by a Cyclodextrin-Based Synthetic Host The discovery of Org 25969 is the result of teamwork with contributions from a number of scientists both inside Organon and outside the company. We would like in particular to acknowledge the following scientists for their invaluable contributions: E. Hutchinson, D. Stevenson, R. Roy, and J. Pick for scaling-up the synthesis; F. Hope, S. Miller, and R. Mason for various in vitro and in vivo pharmacological testing; R. Watson, B. Montgomery, P. Desmond, and A. Osprey for all their analytical effort; and R. McGuire and J. Mestres for graphical presentation of the X-ray crystal structure of the Org 25969–rocuronium complex (Figure 3). We would also like to thank Prof. A. Cooper of Glasgow University who has critically reproduced our calorimetry data of Org 25969–rocuronium complexation (Figure 2). Angewandte Chemie International Edition ·A. Bom,Mark Philip Bradley,Rajkumari Kalpana Devi,John K. Clark,J. van Egmond,Helen Feilden,E.J. MacLean,Alan W. Muir,Ronald Palin,David C. Rees,Ming‐Qiang Zhang	2002	375
11	Anionic Cyclophanes as Potential Reversal Agents of Muscle Relaxants by Chemical Chelation Bioorganic & Medicinal Chemistry Letters ·Marit H. Haukland,Lee A. Fielding,Francis E. McMurtie,Alan W. Muir,David C. Rees,Simon N. Thorn,Ming-Qiang Zhang	2002	17
12	A Novel Concept of Reversing Neuromuscular Block: Chemical Encapsulation of Rocuronium Bromide by a Cyclodextrin-Based Synthetic Host Angewandte Chemie ·A. Bom,Mark Philip Bradley,Rajkumari Kalpana Devi,John K. Clark,J. van Egmond,Helen Feilden,E.J. MacLean,Alan W. Muir,Ronald Palin,David C. Rees,Ming‐Qiang Zhang	2002	173
13	Cyclodextrin-Derived Host Molecules as Reversal Agents for the Neuromuscular Blocker Rocuronium Bromide: Synthesis and Structure−Activity Relationships Journal of Medicinal Chemistry ·Julia M. Adam,David Jonathan Bennett,A. Bom,John K. Clark,Helen Feilden,Edward J. Hutchinson,Ronald Palin,操桐生,David C. Rees,Georgina M. Rosair,Donald Stevenson,Gary J. Tarver,Ming‐Qiang Zhang	2002	190
14	α-Chloronitroso compounds derived from carbohydrate ketones: cycloadditions with cyclic dienes, a synthesis of (−)-physoperuvine and a formal synthesis of (+)-epibatidine Journal of the Chemical Society Perkin Transactions 1 ·Adrian Hall,Patrick D. Bailey,David C. Rees,Georgina M. Rosair,R. H. WIGHTMAN	2000	29
15	A review of recent applications of cyclodextrins for drug discovery Expert Opinion on Therapeutic Patents ·L Lieto,David C. Rees	1999	31
16	Poorly performed lung function tests--the answer is not blowing in the wind. PubMed ·Elizabeth C. Behringer,David C. Rees,Joseph Martí Folguera	1991	0

About David C. Rees

David C. Rees is a scholar working on Developmental Neuroscience, Computational Theory and Mathematics, Anesthesiology and Pain Medicine, Organic Chemistry and Toxicology, having authored 16 papers that have together received 3.1k indexed citations. Recurring topics across this work include Computational Drug Discovery Methods (6 papers), Chemical Synthesis and Analysis (5 papers), Click Chemistry and Applications (4 papers), Catalytic C–H Functionalization Methods (2 papers), Microbial Natural Products and Biosynthesis (2 papers), Anesthesia and Neurotoxicity Research (2 papers), Synthesis and Catalytic Reactions (2 papers) and Pharmaceutical Economics and Policy (2 papers). The work is most often cited by research in Anesthesiology and Pain Medicine (398 citations), Organic Chemistry (1.5k citations), Developmental Neuroscience (201 citations), Pharmaceutical Science (206 citations) and Computational Theory and Mathematics (507 citations). David C. Rees has collaborated with scholars based in United Kingdom, Netherlands and Switzerland. Frequent co-authors include Christopher W. Murray, Andrew W. Thomas, Luis C. Misal Castro, David M. Wilson, Anthony Wood, Ian Churcher, David C. Blakemore, Robin A. E. Carr, Miles Congreve and Ronald Palin. Their work appears in journals such as Journal of Medicinal Chemistry, Angewandte Chemie International Edition, Nature Chemistry, Chemical Science and RSC Medicinal Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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