Howard T. Jacobs

17.3k citations

200 papers · 12.2k indexed · 3 hit papers · h-index 49

Impact in

Aging top 0.1%
- Genetics, Aging, and Longevity in Model Organisms
Clinical Biochemistry top 0.05%
- Metabolism and Genetic Disorders

Papers in

Aging 18
- Genetics, Aging, and Longevity in Model Organisms 18
Clinical Biochemistry 42
- Metabolism and Genetic Disorders 42

Co-authors: Ian Holt Johannes N. Spelbrink Anja T. Rovio Nils‐Göran Larsson Anna Wredenberg Rolf Wibom Aleksandra Trifunović Pierre Rustin
Journals: EMBO Reports (18 papers)Nucleic Acids Research (12 papers)Trends in Genetics (10 papers)Journal of Biological Chemistry (8 papers)Human Molecular Genetics (8 papers)
Partner nations: Finland United Kingdom United States

In The Last Decade

Howard T. Jacobs

197 papers receiving 12.0k citations

Hit Papers

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Mitochondrial electron transport chain is necessary for NLRP3 inflammasome activation 2022 · 216 citations

Peers

Countries citing papers authored by Howard T. Jacobs

Since Specialization

Citations

This map shows the geographic impact of Howard T. Jacobs's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Howard T. Jacobs with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Howard T. Jacobs more than expected).

Fields of papers citing papers by Howard T. Jacobs

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Howard T. Jacobs. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Howard T. Jacobs. The network helps show where Howard T. Jacobs may publish in the future.

Co-authors

The 25 scholars most cited alongside Howard T. Jacobs, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Howard T. Jacobs Line = papers co-authored together Howard T. Jacobs links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Mitochondria: great balls of fire FEBS Journal ·Howard T. Jacobs, Pierre Rustin, Paule Bénit, Dan Davidi, Mügen Terzioglu	2024	4
2	Mitochondrial temperature homeostasis resists external metabolic stresses eLife ·Mügen Terzioglu, Kristo Veeroja, Toni Montonen, Teemu O. Ihalainen, Tiina S. Salminen, Paule Bénit, Pierre Rustin, Young‐Tae Chang, Takeharu Nagai, Howard T. Jacobs	2023	8
3	Alternative oxidase causes cell type- and tissue-specific responses in mutator mice Life Science Alliance ·Lilli Ikonen, Sini Pirnes-Karhu, Swagat Pradhan, Howard T. Jacobs, Marten Szibor, Anu Suomalainen	2023	4
4	Mitochondrial electron transport chain is necessary for NLRP3 inflammasome activation Nature Immunology ·Leah K. Billingham, Joshua S. Stoolman, Karthik Vasan, Arianne E Rodriguez, Taylor A. Poor, Marten Szibor, Howard T. Jacobs, Colleen R. Reczek, Aida Rashidi, Peng Zhang, Jason Miska, Navdeep S. Chandel Hit paper breakdown →	2022	216
5	Alternative oxidase encoded by sequence-optimized and chemically-modified RNA transfected into mammalian cells is catalytically active Gene Therapy ·Luca Giordano, Manish K. Aneja, Natascha Sommer, Nasim Alebrahimdehkordi, Alireza Seraji, Norbert Weißmann, Carsten Rudolph, Christian Plank, Howard T. Jacobs, Marten Szibor	2021	8
6	A second hybrid-binding domain modulates the activity of Drosophila ribonuclease H1 The Journal of Biochemistry ·Jose M. González de Cózar, Maria Carretero-Junquera, Grzegorz L. Ciesielski, Sini Miettinen, Markku Varjosalo, Laurie S. Kaguni, Éric Dufour, Howard T. Jacobs	2020	2
7	Respiratory chain signalling is essential for adaptive remodelling following cardiac ischaemia Journal of Cellular and Molecular Medicine ·Marten Szibor, Rolf Schreckenberg, Zemfira Gizatullina, Éric Dufour, Marion Wiesnet, Praveen K. Dhandapani, Grażyna Dębska–Vielhaber, Juliana Heidler, Ilka Wittig, Tuula A. Nyman, Ulrich Gärtner, Andrew Hall, Victoria R. Pell, Carlo Viscomi, Thomas Krieg, Michael P. Murphy, Thomas Braun, Frank N. Gellerich, Klaus‐Dieter Schlüter, Howard T. Jacobs	2020	18
8	Effects on Dopaminergic Neurons Are Secondary in COX-Deficient Locomotor Dysfunction in Drosophila iScience ·Cagri Yalgin, Bohdana M. Rovenko, Ana Andjelković, M. Neefjes, Burak Oymak, Éric Dufour, Ville Hietakangas, Howard T. Jacobs	2020	4
9	Minimal effects of spargel (PGC-1) overexpression in a Drosophila mitochondrial disease model Biology Open ·Jack George, Howard T. Jacobs	2019	5
10	Lethal Interaction of Nuclear and Mitochondrial Genotypes in Drosophila melanogaster G3 Genes Genomes Genetics ·Tiina S. Salminen, Giuseppe Cannino, Marcos T. Oliveira, Päivi Lillsunde, Howard T. Jacobs, Laurie S. Kaguni	2019	11
11	Alternative NADH dehydrogenase extends lifespan and increases resistance to xenobiotics in Drosophila Biogerontology ·Dmytro V. Gospodaryov, Olha Strilbytska, Uliana Semaniuk, Natalia V. Perkhulyn, Bohdana M. Rovenko, Ihor Yurkevych, Ana G. Barata, Tobias P. Dick, Oleh Lushchak, Howard T. Jacobs	2019	21
12	Hyperoxia but not AOX expression mitigates pathological cardiac remodeling in a mouse model of inflammatory cardiomyopathy Scientific Reports ·Praveen K. Dhandapani, Isabel M. Begines-Moreno, Gloria Brea‐Calvo, Ulrich Gärtner, Thomas G. Graeber, Gerardo Javier Sanchez, Rory E. Morty, Kai Schönig, Johanna ten Hoeve, Astrid Wietelmann, Thomas Braun, Howard T. Jacobs, Marten Szibor	2019	14
13	Developmental arrest in Drosophila melanogaster caused by mitochondrial DNA replication defects cannot be rescued by the alternative oxidase Scientific Reports ·Ana Paula Rodrigues, André Ferreira de Camargo, Ana Andjelković, Howard T. Jacobs, Marcos T. Oliveira	2018	10
14	Alternative Oxidase Attenuates Cigarette Smoke–induced Lung Dysfunction and Tissue Damage American Journal of Respiratory Cell and Molecular Biology ·Luca Giordano, Antoine Farnham, Praveen K. Dhandapani, Laura Salminen, Jahnavi Bhaskaran, Robert Voswinckel, Peter Rauschkolb, Susan Scheibe, Natascha Sommer, Christoph Beißwenger, Norbert Weißmann, Thomas Braun, Howard T. Jacobs, Robert Bals, Christian Herr, Marten Szibor	2018	36
15	Expression of alternative oxidase in Drosophila ameliorates diverse phenotypes due to cytochrome oxidase deficiency Human Molecular Genetics ·Kia K. Kemppainen, Juho Rinne, Ashwin Sriram, Matti Lakanmaa, Akbar Zeb, Tea Tuomela, Anna Popplestone, Satpal Singh, Alberto Sanz, Pierre Rustin, Howard T. Jacobs	2013	51
16	Effects on mitochondrial transcription of manipulating mTERF protein levels in cultured human HEK293 cells BMC Molecular Biology ·Anne K. Hyvärinen, Mona K Kumanto, Sanna Marjavaara, Howard T. Jacobs	2010	15
17	Acquisition of the wobble modification in mitochondrial tRNALeu(CUN) bearing the G12300A mutation suppresses the MELAS molecular defect Human Molecular Genetics ·Yohei Kirino, Takehiro Yasukawa, Sanna Marjavaara, Howard T. Jacobs, Ian Holt, Kimitsuna Watanabe, Tsutomu Suzuki	2006	31
18	Mitochondrial DNA mutations in patients with postlingual, nonsyndromic hearing impairment European Journal of Human Genetics ·Howard T. Jacobs, Timothy Hutchin, Timo Käppi, Greta Gillies, Kia Minkkinen, John Walker, Karen Thompson, Anja T. Rovio, Massimo Carella, Salvatore Melchionda, Leopoldo Zelante, Paolo Gasparini, Ilmari Pyykkö, Zahid H. Shah, Massimo Zeviani, Robert F. Mueller	2004	99
19	Mitochondrial Deafness Annals of Medicine ·Howard T. Jacobs	1997	27
20	Molecular Phenotype of a Human Lymphoblastoid Cell-line Homoplasmic for the np 7445 Deafness-associated Mitochondrial Mutation Human Molecular Genetics ·Fiona Reid, Anja T. Rovio, Ian Holt, Howard T. Jacobs	1997	42

About Howard T. Jacobs

Howard T. Jacobs is a scholar working on Aging, Clinical Biochemistry, Molecular Biology, Physiology and Cellular and Molecular Neuroscience, having authored 200 papers that have together received 12.2k indexed citations. Recurring topics across this work include Mitochondrial Function and Pathology (130 papers), ATP Synthase and ATPases Research (42 papers), Metabolism and Genetic Disorders (42 papers), RNA and protein synthesis mechanisms (41 papers), RNA modifications and cancer (25 papers), DNA Repair Mechanisms (20 papers), RNA Research and Splicing (19 papers) and Genetics, Aging, and Longevity in Model Organisms (18 papers). The work is most often cited by research in Aging (890 citations), Clinical Biochemistry (2.8k citations), Molecular Biology (9.5k citations), Immunology (1.2k citations) and Biological Psychiatry (134 citations). Howard T. Jacobs has collaborated with scholars based in Finland, United Kingdom and United States. Frequent co-authors include Ian Holt, Johannes N. Spelbrink, Anja T. Rovio, Nils‐Göran Larsson, Anna Wredenberg, Rolf Wibom, Aleksandra Trifunović, Pierre Rustin, Maria Falkenberg and Carl E.G. Bruder. Their work appears in journals such as EMBO Reports, Nucleic Acids Research, Trends in Genetics, Journal of Biological Chemistry and Human Molecular Genetics.

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