Takeharu Nagai

20.4k total citations · 6 hit papers
228 papers, 15.4k citations indexed

About

Takeharu Nagai is a scholar working on Molecular Biology, Biophysics and Cellular and Molecular Neuroscience. According to data from OpenAlex, Takeharu Nagai has authored 228 papers receiving a total of 15.4k indexed citations (citations by other indexed papers that have themselves been cited), including 138 papers in Molecular Biology, 87 papers in Biophysics and 61 papers in Cellular and Molecular Neuroscience. Recurrent topics in Takeharu Nagai's work include Advanced Fluorescence Microscopy Techniques (79 papers), Photoreceptor and optogenetics research (41 papers) and bioluminescence and chemiluminescence research (37 papers). Takeharu Nagai is often cited by papers focused on Advanced Fluorescence Microscopy Techniques (79 papers), Photoreceptor and optogenetics research (41 papers) and bioluminescence and chemiluminescence research (37 papers). Takeharu Nagai collaborates with scholars based in Japan, United States and Canada. Takeharu Nagai's co-authors include Atsushi Miyawaki, Katsuhiko Mikoshiba, Mie Kubota, Keiji Ibata, Tomoki Matsuda, Jun Aruga, Masahiro Nakano, Asako Sakaue‐Sawano, Yasunori Hayashi and Kenichi Okamoto and has published in prestigious journals such as Nature, Science and Proceedings of the National Academy of Sciences.

In The Last Decade

Takeharu Nagai

220 papers receiving 15.2k citations

Hit Papers

A variant of yellow fluorescent protein with fast and eff... 2001 2026 2009 2017 2002 2011 2004 2009 2001 500 1000 1.5k 2.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. A variant of yellow fluorescent protein with fast and efficient maturation for cell-biological applications
    2002 2.3k citations Takeharu Nagai, Atsushi Miyawaki et al. profile →
  2. An Expanded Palette of Genetically Encoded Ca 2+ Indicators
    2011 993 citations Yongxin Zhao, Jiahui Wu et al. Science profile →
  3. Expanded dynamic range of fluorescent indicators for Ca 2+ by circularly permuted yellow fluorescent proteins
    2004 844 citations Takeharu Nagai, Shuichi Yamada et al. Proceedings of the National Academy of Sciences profile →
  4. Visualization of ATP levels inside single living cells with fluorescence resonance energy transfer-based genetically encoded indicators
    2009 820 citations Hiromi Imamura, Kenta Saito et al. Proceedings of the National Academy of Sciences profile →
  5. Circularly permuted green fluorescent proteins engineered to sense Ca 2+
    2001 786 citations Takeharu Nagai, Atsushi Miyawaki et al. Proceedings of the National Academy of Sciences profile →
  6. Rapid and persistent modulation of actin dynamics regulates postsynaptic reorganization underlying bidirectional plasticity
    2004 668 citations Takeharu Nagai, Atsushi Miyawaki et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Takeharu Nagai Japan 54 10.6k 4.1k 3.2k 1.8k 1.3k 228 15.4k
Michael Z. Lin United States 49 11.0k 1.0× 5.6k 1.4× 2.3k 0.7× 2.1k 1.2× 691 0.5× 107 17.2k
Thomas J. Deerinck United States 61 9.2k 0.9× 2.8k 0.7× 1.4k 0.4× 3.0k 1.7× 607 0.5× 126 14.9k
Martin Chalfie United States 57 10.1k 0.9× 3.1k 0.7× 1.8k 0.6× 2.2k 1.3× 1.4k 1.1× 119 17.6k
Alice Y. Ting United States 63 14.1k 1.3× 2.1k 0.5× 2.4k 0.8× 6.1k 3.5× 770 0.6× 128 21.4k
Ehud Y. Isacoff United States 75 11.1k 1.0× 10.3k 2.5× 1.4k 0.4× 1.7k 1.0× 651 0.5× 192 18.6k
Loren L. Looger United States 62 8.9k 0.8× 10.8k 2.6× 3.5k 1.1× 1.7k 0.9× 858 0.6× 141 21.0k
Leslie M. Loew United States 60 6.3k 0.6× 3.8k 0.9× 2.5k 0.8× 1.0k 0.6× 326 0.2× 230 12.6k
Ian Parker United States 74 10.7k 1.0× 6.2k 1.5× 1.1k 0.4× 2.3k 1.3× 511 0.4× 283 19.5k
Eric R. Schreiter United States 31 4.4k 0.4× 5.9k 1.4× 1.9k 0.6× 945 0.5× 328 0.2× 50 12.0k
Sergey Lukyanov Russia 59 12.1k 1.1× 2.6k 0.6× 5.3k 1.7× 1.4k 0.8× 2.0k 1.5× 150 18.7k

Countries citing papers authored by Takeharu Nagai

Since Specialization
Citations

This map shows the geographic impact of Takeharu Nagai's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Takeharu Nagai with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Takeharu Nagai more than expected).

Fields of papers citing papers by Takeharu Nagai

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Takeharu Nagai. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Takeharu Nagai. The network helps show where Takeharu Nagai may publish in the future.

Co-authorship network of co-authors of Takeharu Nagai

This figure shows the co-authorship network connecting the top 25 collaborators of Takeharu Nagai. A scholar is included among the top collaborators of Takeharu Nagai based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Takeharu Nagai. Takeharu Nagai is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Goda, Keisuke, Tatsushi Igaki, Bernd Kuhn, et al.. (2025). Japan can be a science heavyweight once more — if it rethinks funding. Nature. 638(8050). 318–320.
2.
Nakaoka, Hidenori, Yusuke Hara, Yoshiyuki Arai, et al.. (2025). Mesoscale heterogeneity is a critical determinant for spiral pattern formation in developing social amoeba. Scientific Reports. 15(1). 1422–1422. 1 indexed citations
3.
Oketani, Ryosuke, Kazunori Sugiura, Tomoki Matsuda, et al.. (2024). Selective-plane-activation structured illumination microscopy. Nature Methods. 21(5). 889–896. 13 indexed citations
4.
Iwano, Megumi, Noriyuki Suetsugu, Ryuichi Nishihama, et al.. (2024). MID1-COMPLEMENTING ACTIVITY regulates cell proliferation and development via Ca2+ signaling in Marchantia polymorpha. PLANT PHYSIOLOGY. 197(1). 1 indexed citations
5.
Bannai, Hiroko, Akihiko Takashima, Yoshiyuki Soeda, et al.. (2024). Research on the molecular mechanism of singularity phenomenon in neurological disorders. Biophysics and Physicobiology. 21(Supplemental). n/a–n/a. 1 indexed citations
6.
Wazawa, Tetsuichi, et al.. (2024). Extremely Sensitive Genetically Encoded Temperature Indicator Enabling Measurement at the Organelle Level. ACS Sensors. 9(8). 3889–3897. 4 indexed citations
7.
Terzioglu, Mügen, Teemu O. Ihalainen, Tiina S. Salminen, et al.. (2023). Mitochondrial temperature homeostasis resists external metabolic stresses. eLife. 12. 8 indexed citations
8.
Wazawa, Tetsuichi & Takeharu Nagai. (2023). Joule heating involving ion currents through channel proteins. Biophysics and Physicobiology. 20(3). n/a–n/a. 3 indexed citations
9.
Wazawa, Tetsuichi, et al.. (2022). Intracellular Heat Transfer and Thermal Property Revealed by Kilohertz Temperature Imaging with a Genetically Encoded Nanothermometer. Nano Letters. 22(14). 5698–5707. 25 indexed citations
10.
Sugiura, Kazunori, Hajime Shinoda, Kai Lu, et al.. (2021). Visible-Wavelength Multiphoton Activation Confocal Microscopy. ACS Photonics. 8(9). 2666–2673. 2 indexed citations
11.
Hara, Satoshi, Wei‐Chih Chen, Takashi Washio, Tetsuichi Wazawa, & Takeharu Nagai. (2019). SPoD-Net: Fast Recovery of Microscopic Images Using Learned ISTA. Asian Conference on Machine Learning. 694–709. 1 indexed citations
12.
Suzuki, Kazushi & Takeharu Nagai. (2017). Recent progress in expanding the chemiluminescent toolbox for bioimaging. Current Opinion in Biotechnology. 48. 135–141. 44 indexed citations
13.
Nakano, Masahiro, Kenta Saito, Tomonobu M. Watanabe, et al.. (2015). Expanded palette of Nano-lanterns for real-time multicolor luminescence imaging. Proceedings of the National Academy of Sciences. 112(14). 4352–4356. 102 indexed citations
14.
Zhao, Yongxin, Jiahui Wu, Takayuki Teramoto, et al.. (2011). An Expanded Palette of Genetically Encoded Ca 2+ Indicators. Science. 333(6051). 1888–1891. 993 indexed citations breakdown →
15.
Imamura, Hiromi, Kenta Saito, Ryota Iino, et al.. (2009). Visualization of ATP levels inside single living cells with fluorescence resonance energy transfer-based genetically encoded indicators. Proceedings of the National Academy of Sciences. 106(37). 15651–15656. 820 indexed citations breakdown →
16.
Takemoto, Kiwamu, Erina Kuranaga, Ayako Tonoki, et al.. (2007). Local initiation of caspase activation in Drosophila salivary gland programmed cell death in vivo. Proceedings of the National Academy of Sciences. 104(33). 13367–13372. 54 indexed citations
17.
Kohyama, Jun, Akinori Tokunaga, Yūkō Fujita, et al.. (2005). Visualization of spatiotemporal activation of Notch signaling: Live monitoring and significance in neural development. Developmental Biology. 286(1). 311–325. 63 indexed citations
18.
Nagai, Takeharu, Shuichi Yamada, Takashi Tominaga, Michinori Ichikawa, & Atsushi Miyawaki. (2004). Expanded dynamic range of fluorescent indicators for Ca 2+ by circularly permuted yellow fluorescent proteins. Proceedings of the National Academy of Sciences. 101(29). 10554–10559. 844 indexed citations breakdown →
19.
Iwano, Megumi, Hiroshi Shiba, Fang‐Sik Che, et al.. (2004). Ca2+ Dynamics in a Pollen Grain and Papilla Cell during Pollination of Arabidopsis. PLANT PHYSIOLOGY. 136(3). 3562–3571. 137 indexed citations
20.
Aruga, Jun, Osamu Minowa, Hiroyuki Yaginuma, et al.. (1998). MouseZic1Is Involved in Cerebellar Development. Journal of Neuroscience. 18(1). 284–293. 168 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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