Ian Holt

14.8k total citations · 2 hit papers
160 papers, 11.0k citations indexed

About

Ian Holt is a scholar working on Molecular Biology, Clinical Biochemistry and Cellular and Molecular Neuroscience. According to data from OpenAlex, Ian Holt has authored 160 papers receiving a total of 11.0k indexed citations (citations by other indexed papers that have themselves been cited), including 144 papers in Molecular Biology, 73 papers in Clinical Biochemistry and 22 papers in Cellular and Molecular Neuroscience. Recurrent topics in Ian Holt's work include Mitochondrial Function and Pathology (99 papers), Metabolism and Genetic Disorders (73 papers) and ATP Synthase and ATPases Research (39 papers). Ian Holt is often cited by papers focused on Mitochondrial Function and Pathology (99 papers), Metabolism and Genetic Disorders (73 papers) and ATP Synthase and ATPases Research (39 papers). Ian Holt collaborates with scholars based in United Kingdom, United States and Finland. Ian Holt's co-authors include A. E. Harding, J A Morgan-Hughes, Aurelio Reyes, Howard T. Jacobs, Richard Petty, Lawrence Kazak, Takehiro Yasukawa, Mingyao Yang, Glenn E. Morris and Johannes N. Spelbrink and has published in prestigious journals such as Nature, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Ian Holt

158 papers receiving 10.7k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Deletions of muscle mitochondrial DNA in patients with mitochondrial myopathies

1988 1.4k citations Ian Holt, A. E. Harding et al. profile →
A new mitochondrial disease associated with mitochondrial DNA heteroplasmy.

1990 776 citations Ian Holt, A. E. Harding et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Ian Holt United Kingdom	60	10.0k	4.7k	1.1k	657	486	160	11.0k
Joanna Poulton United Kingdom	51	6.1k 0.6×	3.0k 0.6×	593 0.5×	789 1.2×	561 1.2×	197	7.9k
Maria Falkenberg Sweden	46	8.3k 0.8×	2.9k 0.6×	528 0.5×	579 0.9×	923 1.9×	91	9.4k
Orly Elpeleg Israel	56	7.0k 0.7×	3.2k 0.7×	917 0.8×	1.6k 2.4×	728 1.5×	244	10.4k
Sarah E. Calvo United States	35	6.7k 0.7×	2.0k 0.4×	478 0.4×	635 1.0×	724 1.5×	49	7.8k
Robert N. Lightowlers United Kingdom	50	7.0k 0.7×	2.4k 0.5×	585 0.5×	463 0.7×	431 0.9×	142	7.8k
Jan‐Willem Taanman United Kingdom	43	5.8k 0.6×	1.9k 0.4×	1.3k 1.2×	604 0.9×	864 1.8×	115	7.6k
Marie T. Lott United States	38	8.4k 0.8×	4.2k 0.9×	860 0.8×	1.3k 1.9×	754 1.6×	53	9.8k
Josseline Kaplan France	41	6.9k 0.7×	660 0.1×	911 0.8×	1.4k 2.2×	590 1.2×	172	9.0k
Kirby D. Smith United States	39	4.6k 0.5×	879 0.2×	236 0.2×	1.5k 2.3×	900 1.9×	93	6.3k
Konstantin Khrapko United States	32	4.0k 0.4×	887 0.2×	530 0.5×	439 0.7×	380 0.8×	74	4.8k

Countries citing papers authored by Ian Holt

Since Specialization

Citations

This map shows the geographic impact of Ian Holt's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ian Holt with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ian Holt more than expected).

Fields of papers citing papers by Ian Holt

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ian Holt. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ian Holt. The network helps show where Ian Holt may publish in the future.

Co-authorship network of co-authors of Ian Holt

This figure shows the co-authorship network connecting the top 25 collaborators of Ian Holt. A scholar is included among the top collaborators of Ian Holt based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Ian Holt. Ian Holt is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Holt, Ian, et al.. (2024). Proteomic characterization of human LMNA-related congenital muscular dystrophy muscle cells. Neuromuscular Disorders. 38. 26–41. 2 indexed citations

Brown, Sharon J., Rachel Kline, Silvia A. Synowsky, et al.. (2022). The Proteome Signatures of Fibroblasts from Patients with Severe, Intermediate and Mild Spinal Muscular Atrophy Show Limited Overlap. Cells. 11(17). 2624–2624. 6 indexed citations

Holt, Ian. (2022). R-Loops and Mitochondrial DNA Metabolism. Methods in molecular biology. 2528. 173–202. 7 indexed citations

Loera‐Valencia, Raúl, Julen Goikolea, Patricia Rodriguez‐Rodriguez, et al.. (2022). Defects of Nutrient Signaling and Autophagy in Neurodegeneration. Frontiers in Cell and Developmental Biology. 10. 836196–836196. 13 indexed citations

Schwartz, Christine, Martina Fischer, Kamel Mamchaoui, et al.. (2017). Lamins and nesprin-1 mediate inside-out mechanical coupling in muscle cell precursors through FHOD1. Scientific Reports. 7(1). 1253–1253. 38 indexed citations

Malena, Adriana, Boris Pantic, Gianluca Sgarbi, et al.. (2016). Mitochondrial quality control: Cell-type-dependent responses to pathological mutant mitochondrial DNA. Autophagy. 12(11). 2098–2112. 25 indexed citations

Ghanem, Dana, Francisco-José Fernández-Gómez, Fanny Jumeau, et al.. (2014). Tau exon 2 responsive elements deregulated in myotonic dystrophy type I are proximal to exon 2 and synergistically regulated by MBNL1 and MBNL2. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1842(4). 654–664. 26 indexed citations

Holt, Ian, Virginie Jacquemin, Majid Fardaei, et al.. (2008). Muscleblind-Like Proteins. American Journal Of Pathology. 174(1). 216–227. 59 indexed citations

Iacovino, Michelina, Hiroshi Sembongi, Monika Bokori-Brown, et al.. (2008). The conserved translocase Tim17 prevents mitochondrial DNA loss. Human Molecular Genetics. 18(1). 65–74. 20 indexed citations

10.

Reyes, Aurelio, Takehiro Yasukawa, & Ian Holt. (2007). Analysis of Replicating Mitochondrial DNA by Two-Dimensional Agarose Gel Electrophoresis. Methods in molecular biology. 372. 219–232. 12 indexed citations

11.

Bokori-Brown, Monika & Ian Holt. (2006). Expression of Algal Nuclear ATP Synthase Subunit 6 in Human Cells Results in Protein Targeting to Mitochondria but No Assembly into ATP Synthase. Rejuvenation Research. 9(4). 455–469. 31 indexed citations

12.

Tyynismaa, Henna, Hiroshi Sembongi, Monika Bokori-Brown, et al.. (2004). Twinkle helicase is essential for mtDNA maintenance and regulates mtDNA copy number. Human Molecular Genetics. 13(24). 3219–3227. 197 indexed citations

13.

Holt, Ian. (2003). Genetics of mitochondrial diseases. Oxford University Press eBooks. 10 indexed citations

14.

Holt, Ian, Lisa Clements, S. Manilal, & Glenn E. Morris. (2001). How Does a g993t Mutation in the Emerin Gene Cause Emery–Dreifuss Muscular Dystrophy?. Biochemical and Biophysical Research Communications. 287(5). 1129–1133. 12 indexed citations

15.

Holt, Ian & Michael J. Marshall. (1998). Integrin subunit β3 plays a crucial role in the movement of osteoclasts from the periosteum to the bone surface. Journal of Cellular Physiology. 175(1). 1–9. 14 indexed citations

16.

Holt, Ian. (1997). Behaviour of a population of partially duplicated mitochondrial DNA molecules in cell culture: segregation, maintenance and recombination dependent upon nuclear background. Human Molecular Genetics. 6(8). 1251–1260. 78 indexed citations

17.

Holt, Ian, M.W.J. Davie, Isobel Braidman, & Michael J. Marshall. (1994). Interleukin-6 does not mediate the stimulation by prostaglandin E2, parathyroid hormone, or 1,25 dihydroxyvitamin D3 of osteoclast differentiation and bone resorption in neonatal mouse parietal bones. Calcified Tissue International. 55(2). 114–119. 24 indexed citations

18.

Schapira, Anthony H.V., Ian Holt, Mary G. Sweeney, et al.. (1990). Mitochondrial DNA analysis in Parkinson's disease. Movement Disorders. 5(4). 294–297. 87 indexed citations

19.

Holt, Ian, et al.. (1989). MOLECULAR GENETICS OF AMYLOID NEUROPATHY IN EUROPE. The Lancet. 333(8637). 524–526. 37 indexed citations

20.

Holt, Ian, A. E. Harding, & J A Morgan-Hughes. (1988). Mitochondrial DNA polymorphism in mitochondrial myopathy. Human Genetics. 79(1). 53–57. 27 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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