Howard L. Weiner

106.9k total citations · 31 hit papers
826 papers, 73.1k citations indexed

About

Howard L. Weiner is a scholar working on Immunology, Pathology and Forensic Medicine and Molecular Biology. According to data from OpenAlex, Howard L. Weiner has authored 826 papers receiving a total of 73.1k indexed citations (citations by other indexed papers that have themselves been cited), including 325 papers in Immunology, 247 papers in Pathology and Forensic Medicine and 139 papers in Molecular Biology. Recurrent topics in Howard L. Weiner's work include Multiple Sclerosis Research Studies (238 papers), T-cell and B-cell Immunology (185 papers) and Immunotherapy and Immune Responses (133 papers). Howard L. Weiner is often cited by papers focused on Multiple Sclerosis Research Studies (238 papers), T-cell and B-cell Immunology (185 papers) and Immunotherapy and Immune Responses (133 papers). Howard L. Weiner collaborates with scholars based in United States, Canada and Israel. Howard L. Weiner's co-authors include Vijay K. Kuchroo, David A. Hafler, Estelle Bettelli, Mohamed Oukka, Samia J. Khoury, Thomas Korn, Yijun Carrier, Francisco J. Quintana, Terry B. Strom and Wenda Gao and has published in prestigious journals such as Nature, Science and New England Journal of Medicine.

In The Last Decade

Howard L. Weiner

802 papers receiving 71.3k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

2006 5.6k citations Howard L. Weiner et al. profile →
Identification of a unique TGF-β–dependent molecular and functional signature in microglia

2013 1.9k citations Oleg Butovsky, Amanda J. Lanser et al. profile →
Regulatory T Cell Clones Induced by Oral Tolerance: Suppression of Autoimmune Encephalomyelitis

1994 1.6k citations Howard L. Weiner et al. profile →
Control of Treg and TH17 cell differentiation by the aryl hydrocarbon receptor

2008 1.5k citations Francisco J. Quintana, Howard L. Weiner et al. profile →
Loss of Functional Suppression by CD4+CD25+ Regulatory T Cells in Patients with Multiple Sclerosis

2004 1.5k citations Howard L. Weiner et al. profile →
B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: Application to autoimmune disease therapy

1995 1.4k citations Howard L. Weiner et al. profile →
Alemtuzumab for patients with relapsing multiple sclerosis after disease-modifying therapy: a randomised controlled phase 3 trial

2012 884 citations Howard L. Weiner et al. profile →
Alemtuzumab versus interferon beta 1a as first-line treatment for patients with relapsing-remitting multiple sclerosis: a randomised controlled phase 3 trial

2012 883 citations Howard L. Weiner et al. profile →
T-cell recognition of an immuno-dominant myelin basic protein epitope in multiple sclerosis

1990 764 citations Howard L. Weiner et al. profile →
Oral Tolerance: Immunologic Mechanisms and Treatment of Animal and Human Organ-Specific Autoimmune Diseases by Oral Administration of Autoantigens

1994 746 citations Howard L. Weiner, Samia J. Khoury et al. profile →
CCR5⁺and CXCR3⁺T cells are increased in multiple sclerosis and their ligands MIP-1α and IP-10 are expressed in demyelinating brain lesions

1999 711 citations Howard L. Weiner et al. Proceedings of the National Academy of Sciences profile →
MicroRNA-124 promotes microglia quiescence and suppresses EAE by deactivating macrophages via the C/EBP-α–PU.1 pathway

2010 678 citations Howard L. Weiner et al. profile →
Peripheral deletion of antigen-reactive T cells in oral tolerance

1995 667 citations Howard L. Weiner et al. profile →
A dominant function for interleukin 27 in generating interleukin 10–producing anti-inflammatory T cells

2007 664 citations Howard L. Weiner et al. profile →
Multiple Sclerosis: Mechanisms and Immunotherapy

2018 659 citations Howard L. Weiner et al. profile →
Intensive Immunosuppression in Progressive Multiple Sclerosis

1983 651 citations Stephen L. Hauser, Howard L. Weiner et al. profile →
Myelin Oligodendrocyte Glycoprotein–specific T Cell Receptor Transgenic Mice Develop Spontaneous Autoimmune Optic Neuritis

2003 638 citations Howard L. Weiner et al. profile →
Microglial signatures and their role in health and disease

2018 637 citations Oleg Butovsky, Howard L. Weiner profile →
Suppressor T cells generated by oral tolerization to myelin basic protein suppress both in vitro and in vivo immune responses by the release of transforming growth factor beta after antigen-specific triggering.

1992 629 citations Howard L. Weiner et al. Proceedings of the National Academy of Sciences profile →
Oral tolerance to myelin basic protein and natural recovery from experimental autoimmune encephalomyelitis are associated with downregulation of inflammatory cytokines and differential upregulation of transforming growth factor beta, interleukin 4, and prostaglandin E expression in the brain.

1992 621 citations Samia J. Khoury, Howard L. Weiner et al. profile →
Oral tolerance: immune mechanisms and treatment of autoimmune diseases

1997 600 citations Howard L. Weiner profile →
The Host Shapes the Gut Microbiota via Fecal MicroRNA

2016 595 citations Andre Pires da Cunha, Rafael M. Rezende et al. profile →
The aryl hydrocarbon receptor interacts with c-Maf to promote the differentiation of type 1 regulatory T cells induced by IL-27

2010 593 citations Francisco J. Quintana, Howard L. Weiner et al. profile →
Effects of Oral Administration of Type II Collagen on Rheumatoid Arthritis

1993 524 citations Howard L. Weiner et al. profile →
Induction of anergy or active suppression following oral tolerance is determined by antigen dosage.

1994 515 citations Howard L. Weiner et al. Proceedings of the National Academy of Sciences profile →
Oral tolerance

2005 506 citations Howard L. Weiner et al. profile →
Loss of ‘homeostatic’ microglia and patterns of their activation in active multiple sclerosis

2017 483 citations Oleg Butovsky, Howard L. Weiner et al. profile →
Oral fingolimod in primary progressive multiple sclerosis (INFORMS): a phase 3, randomised, double-blind, placebo-controlled trial

2016 335 citations Howard L. Weiner et al. profile →
Evaluation of No Evidence of Disease Activity in a 7-Year Longitudinal Multiple Sclerosis Cohort

2014 297 citations Brian C. Healy, Tanuja Chitnis et al. profile →
Gut Microbiome in Progressive Multiple Sclerosis

2021 190 citations Laura M. Cox, Shahamat Tauhid et al. profile →
Multiple sclerosis: Neuroimmune crosstalk and therapeutic targeting

2023 120 citations Howard L. Weiner, Francisco J. Quintana et al. profile →

Peers

Countries citing papers authored by Howard L. Weiner

Since Specialization

Citations

This map shows the geographic impact of Howard L. Weiner's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Howard L. Weiner with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Howard L. Weiner more than expected).

Fields of papers citing papers by Howard L. Weiner

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Howard L. Weiner. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Howard L. Weiner. The network helps show where Howard L. Weiner may publish in the future.

Co-authorship network of co-authors of Howard L. Weiner

This figure shows the co-authorship network connecting the top 25 collaborators of Howard L. Weiner. A scholar is included among the top collaborators of Howard L. Weiner based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Howard L. Weiner. Howard L. Weiner is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Faecal mucoprotein MUC2 is decreased in multiple sclerosis and is associated with mucin degrading bacteria 2025 ·EBioMedicine ·(unknown), Federico Montini, Tanuja Chitnis, Laura M. Cox, Howard L. Weiner	3
2	Epilepsy surgery outcomes in children with tuberous sclerosis complex: a systematic review and meta-analysis 2025 ·Journal of Neurosurgery Pediatrics ·Andrew T. Hale, Cody Savage, Dagoberto Estévez-Ordoñez, T. Oliver, (unknown), Shelly Wang, John Ragheb, Aglaia Vignoli, Chad Carlson, (unknown), Yuan Liu, (unknown), Srinivas Chivukula, Aria Fallah, Ismail Mohamed, E. Martina Bebin, Curtis J. Rozzelle, Howard L. Weiner, Shuli Liang, Jeffrey P. Blount	0
3	Unraveling the dual nature of brain CD8+ T cells in Alzheimer’s disease 2024 ·Molecular Neurodegeneration ·Dan Hu, Howard L. Weiner	5
4	Repeat Exchange Autologous Cranioplasty for Recurrent Benign Osteoma: Meta-analysis and Literature Review 2024 ·Journal of Craniofacial Surgery ·(unknown), (unknown), (unknown), Jonathan E. Martin, Howard L. Weiner, Christopher D. Hughes	1
5	A survey of the members of the American Society of Pediatric Neurosurgeons and factors associated with well-being 2024 ·Journal of Neurosurgery Pediatrics ·(unknown), Ann Marie Flannery, (unknown), Paul M. Kanev, (unknown), Chima Oluigbo, Jeffrey S. Raskin, Zulma Tovar-Spinoza, Albert Tu, Howard L. Weiner, Bradley E. Weprin, Chiu‐Hsieh Hsu, Gerald A. Grant, Anthony M. Avellino	0
6	In Search of a Common Language: The Standardized Electrode Nomenclature for Stereoelectroencephalography Applications 2024 ·Journal of Clinical Neurophysiology ·(unknown), Jeffrey Bolton, Jeffrey S. Raskin, Daniel J. Curry, Howard L. Weiner, Phillip L. Pearl, Scellig Stone	0
7	Monocyte regulation by gut microbial signals 2023 ·Trends in Microbiology ·(unknown), Howard L. Weiner	10
8	1692. Increasing incidence of Streptococcus anginosus group intracranial complications of sinusitis, otitis media and mastoiditis in a pediatric population 2023 ·Open Forum Infectious Diseases ·(unknown), (unknown), James J. Dunn, Howard L. Weiner, (unknown), Anthony R. Flores, Sheldon L. Kaplan, Jesús G. Vallejo, J. Chase McNeil	0
9	Behavioral Improvements following Lesion Resection for Pediatric Epilepsy: Pediatric Psychosurgery? 2023 ·Pediatric Neurosurgery ·(unknown), Abdul Wali Khan, Nisha Gadgil, Himanshu Sharma, (unknown), Fatema Malbari, Howard L. Weiner	0
10	Nasal administration of anti-CD3 monoclonal antibody ameliorates disease in a mouse model of Alzheimer’s disease 2023 ·Proceedings of the National Academy of Sciences ·(unknown), Xiaoming Zhang, (unknown), (unknown), Lydia Guo, (unknown), Hadi Abou‐El‐Hassan, (unknown), (unknown), Marília Gerhardt de Oliveira, (unknown), Lei Liu, Oleg Butovsky, Rafael M. Rezende, Howard L. Weiner	13
11	Myeloid cell subsets that express latency-associated peptide promote cancer growth by modulating T cells 2021 ·iScience ·Galina Gabriely, Duanduan Ma, Shafiuddin Siddiqui, Linqing Sun, Nathaniel P. Skillin, Hadi Abou‐El‐Hassan, Thaís G. Moreira, Dustin J. Donnelly, Andre Pires da Cunha, Mai Fujiwara, (unknown), Amee B. Patel, (unknown), Stuart S. Levine, Brian C. Healy, Rafael M. Rezende, Gopal Murugaiyan, Howard L. Weiner	5
12	Regional microglial activation in the substantia nigra is linked with fatigue in MS 2020 ·Neurology Neuroimmunology & Neuroinflammation ·Tarun Singhal, (unknown), Hong Pan, Kelsey Carter, Shipra Dubey, Renxin Chu, Bonnie I. Glanz, Shelley Hurwitz, Shahamat Tauhid, Mi‐Ae Park, Marie Foley Kijewski, Emily Stern, Rohit Bakshi, David Silbersweig, Howard L. Weiner	13
13	Serum antibodies to phosphatidylcholine in MS 2020 ·Neurology Neuroimmunology & Neuroinflammation ·María C. Sádaba, Veit Rothhammer, Úrsula Muñoz, (unknown), Esther Escudero, Pia Kivisäkk, (unknown), Guillermo Izquierdo, Stephen L. Hauser, Sergio E. Baranzini, Jorge R. Oksenberg, Roberto Álvarez‐Lafuente, Rohit Bakshi, Howard L. Weiner, Francisco J. Quintana	17
14	Perioperative Procalcitonin in Predicting Infection in Children Undergoing Surgical Procedures 2020 ·Journal of Surgical Research ·(unknown), (unknown), Sridevi Devaraj, Danielle Guffey, (unknown), Howard L. Weiner, Christopher A. Caldarone, Lara Shekerdemian	1
15	Gray matter microglial activation in relapsing vs progressive MS 2019 ·Neurology Neuroimmunology & Neuroinflammation ·Tarun Singhal, (unknown), Shipra Dubey, Hong Pan, Renxin Chu, Shelley Hurwitz, (unknown), Shahamat Tauhid, David Silbersweig, Emily Stern, Marie Foley Kijewski, Marcelo F. DiCarli, Howard L. Weiner, Rohit Bakshi	34
16	Calorie restriction slows age-related microbiota changes in an Alzheimer’s disease model in female mice 2019 ·Scientific Reports ·Laura M. Cox, Marissa J. Schafer, Jiho Sohn, (unknown), Howard L. Weiner, Stephen D. Ginsberg, Martin J. Blaser	111
17	Disruption of theATP/adenosine balance inCD39^−/−mice is associated with handling‐induced seizures 2017 ·Immunology ·Amanda J. Lanser, Rafael M. Rezende, Stephen Rubino, Paul J. Lorello, Dustin J. Donnelly, Huixin Xu, Lauren A. Lau, Chris G. Dulla, Barbara J. Caldarone, Simon C. Robson, Howard L. Weiner	27
18	Handling changes in MRI acquisition parameters in modeling whole brain lesion volume and atrophy data in multiple sclerosis subjects: Comparison of linear mixed-effect models 2015 ·NeuroImage Clinical ·Alicia S. Chua, Svetlana Egorova, Mark Anderson, Mariann Polgar‐Turcsanyi, Tanuja Chitnis, Howard L. Weiner, Charles R.G. Guttmann, Rohit Bakshi, Brian C. Healy	18
19	Smoking and Disease Progression in Multiple Sclerosis 2009 ·Archives of Neurology ·Brian C. Healy, (unknown), Charles R.G. Guttmann, Tanuja Chitnis, Bonnie I. Glanz, Guy J. Buckle, Maria K. Houtchens, Lynn Stazzone, (unknown), Annika Berger, Yang Duan, Rohit Bakshi, Samia J. Khoury, Howard L. Weiner, Alberto Ascherio	177
20	Anti-immunoglobulin stimulation of murine lymphocytes. I. Age dependency of the proliferative response. 1976 ·Munich Personal RePEc Archive (Ludwig Maximilian University of Munich) ·Howard L. Weiner, John W. Moorhead, Henry N. Claman	65

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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