Harm-Jan Westra

33.2k citations

38 papers · 1.9k · 1 hit paper · h-index 23

Impact in

Genetics top 2%
- Genetic Associations and Epidemiology
- Genetic Mapping and Diversity in Plants and Animals
Cancer Research top 5%
- Cancer-related molecular mechanisms research

Papers in

Molecular Biology 25
- Bioinformatics and Genomic Networks 10
- RNA modifications and cancer 5
- Gene expression and cancer classification 4
- Single-cell and spatial transcriptomics 3
- Epigenetics and DNA Methylation 3
Genetics 20
- Genetic Associations and Epidemiology 13
- Genetic and phenotypic traits in livestock 3
- Chronic Lymphocytic Leukemia Research 3

Co-authors: Lude Franke (28 shared papers)Rudolf S.N. Fehrmann (5 shared papers)Cisca Wijmenga (10 shared papers)Juha Karjalainen (3 shared papers)Tōnu Esko (4 shared papers)Soumya Raychaudhuri (6 shared papers)Joel N. Hirschhorn (2 shared papers)Tune H. Pers (2 shared papers)
Journals: PLoS Genetics (6 papers)Nature Communications (5 papers)Genome biology (3 papers)Nature Genetics (2 papers)BMC Genomics (2 papers)
Partner nations: Netherlands United States United Kingdom

In The Last Decade

Harm-Jan Westra

38 papers receiving 1.9k citations

Harm-Jan Westra's Hit Papers

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Biological interpretation of genome-wide association studies using predicted gene functions 2015 · 359 citations

Peers

Countries citing papers authored by Harm-Jan Westra

Since Specialization

Citations

This map shows the geographic impact of Harm-Jan Westra's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Harm-Jan Westra with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Harm-Jan Westra more than expected).

Fields of papers citing papers by Harm-Jan Westra

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Harm-Jan Westra. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Harm-Jan Westra. The network helps show where Harm-Jan Westra may publish in the future.

Co-authors

The 25 scholars most cited alongside Harm-Jan Westra, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Harm-Jan Westra Line = papers co-authored together Harm-Jan Westra links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 38 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Biological interpretation of genome-wide association studies using predicted gene functions Nature Communications ·Tune H. Pers, Juha Karjalainen, Yingleong Chan, Harm-Jan Westra, Andrew R. Wood, Jian Yang, Julian C. Lui, Sailaja Vedantam, Stefan Gustafsson, Tōnu Esko, Timothy M. Frayling, Elizabeth K. Speliotes, Michael Boehnke, Soumya Raychaudhuri, Rudolf S.N. Fehrmann, Joel N. Hirschhorn, Lude Franke Hit paper breakdown →	2015	359
2	Human Disease-Associated Genetic Variation Impacts Large Intergenic Non-Coding RNA Expression PLoS Genetics ·Vinod Kumar, Harm-Jan Westra, Juha Karjalainen, Daria V. Zhernakova, Tōnu Esko, Barbara Hrdličková, Rodrigo de Almeida, Alexandra Zhernakova, Eva Reinmaa, Urmo Võsa, Marten H. Hofker, Rudolf S.N. Fehrmann, Jingyuan Fu, Sebo Withoff, Andres Metspalu, Lude Franke, Cisca Wijmenga	2013	216
3	Gene expression analysis identifies global gene dosage sensitivity in cancer Nature Genetics ·Rudolf S.N. Fehrmann, Juha Karjalainen, Małgorzata Krajewska, Harm-Jan Westra, David J. Maloney, Anton Simeonov, Tune H. Pers, Joel N. Hirschhorn, Ritsert C. Jansen, Erik Schultes, Herman H. H. B. M. van Haagen, Elisabeth G.E. de Vries, Gerard J. te Meerman, Cisca Wijmenga, Marcel A.T.M. van Vugt, Lude Franke	2015	209
4	Unraveling the Regulatory Mechanisms Underlying Tissue-Dependent Genetic Variation of Gene Expression PLoS Genetics ·Jingyuan Fu, Marcel G. M. Wolfs, Patrick Deelen, Harm-Jan Westra, Rudolf S.N. Fehrmann, Gerard J. te Meerman, Wim A. Buurman, Sander S. Rensen, Harry J.M. Groen, Rinse K. Weersma, Leonard H. van den Berg, Jan H. Veldink, Roel A. Ophoff, Harold Snieder, David A. van Heel, Ritsert C. Jansen, Marten H. Hofker, Cisca Wijmenga, Lude Franke	2012	160
5	From genome to function by studying eQTLs Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease ·Harm-Jan Westra, Lude Franke	2014	110
6	Genotype harmonizer: automatic strand alignment and format conversion for genotype data integration BMC Research Notes ·Patrick Deelen, Marc Jan Bonder, K van der Velde, Harm-Jan Westra, Erwin Winder, Dennis Hendriksen, Lude Franke, Morris A. Swertz	2014	76
7	Disentangling the Effects of Colocalizing Genomic Annotations to Functionally Prioritize Non-coding Variants within Complex-Trait Loci The American Journal of Human Genetics ·Gosia Trynka, Harm-Jan Westra, Kamil Slowikowski, Xinli Hu, Han Xu, Barbara E. Stranger, Robert J. Klein, Buhm Han, Soumya Raychaudhuri	2015	73
8	Pathogenic implications for autoimmune mechanisms derived by comparative eQTL analysis of CD4+ versus CD8+ T cells PLoS Genetics ·Silva Kasela, Kai Kisand, Liina Tserel, Epp Kaleviste, Anu Remm, Krista Fischer, Tōnu Esko, Harm-Jan Westra, Benjamin P. Fairfax, Seiko Makino, Julian C. Knight, Lude Franke, Andres Metspalu, Pärt Peterson, Lili Milani	2017	62
9	Systematic annotation of celiac disease loci refines pathological pathways and suggests a genetic explanation for increased interferon-gamma levels Human Molecular Genetics ·Vinod Kumar, Javier Gutierrez‐Achury, Kartiek Kanduri, Rodrigo Coutinho de Almeida, Barbara Hrdličková, Daria V. Zhernakova, Harm-Jan Westra, Juha Karjalainen, Isis Ricaño-Ponce, Yang Li, Anna Stachurska, Ettje F. Tigchelaar, Wayel H. Abdulahad, Harri Lähdesmäki, Marten H. Hofker, Alexandra Zhernakova, Lude Franke, Riitta Lahesmaa, Cisca Wijmenga, Sebo Withoff	2014	59
10	Mediation Analysis Demonstrates That Trans-eQTLs Are Often Explained by Cis-Mediation: A Genome-Wide Analysis among 1,800 South Asians PLoS Genetics ·Brandon L. Pierce, Tong Lin, Lin Chen, Ronald Rahaman, Maria Argos, Farzana Jasmine, Shantanu Roy, Rachelle Paul-Brutus, Harm-Jan Westra, Lude Franke, Tōnu Esko, Rakibuz Zaman, Tariqul Islam, Mahfuzar Rahman, John A. Baron, Muhammad G. Kibriya, Habibul Ahsan	2014	58
11	An integrative approach for building personalized gene regulatory networks for precision medicine Genome Medicine ·Monique G.P. van der Wijst, Dylan H. de Vries, Harm Brugge, Harm-Jan Westra, Lude Franke	2018	55
12	MixupMapper: correcting sample mix-ups in genome-wide datasets increases power to detect small genetic effects Bioinformatics ·Harm-Jan Westra, Ritsert C. Jansen, Rudolf S.N. Fehrmann, Gerard J. te Meerman, David A. van Heel, Cisca Wijmenga, Lude Franke	2011	55
13	Single-cell RNA-sequencing of peripheral blood mononuclear cells reveals widespread, context-specific gene expression regulation upon pathogenic exposure Nature Communications ·Roy Oelen, Dylan H. de Vries, Harm Brugge, M. Grace Gordon, Martijn Vochteloo, Chun Ye, Harm-Jan Westra, Lude Franke, Monique G.P. van der Wijst	2022	53
14	Genetic variants in the region of the C1q genes are associated with rheumatoid arthritis Clinical & Experimental Immunology ·Leendert A. Trouw, Nina Daha, Fina Kurreeman, Stefan Böhringer, George N. Goulielmos, Harm-Jan Westra, Alexandra Zhernakova, Lude Franke, Erich Stahl, E. W. Nivine Levarht, Gerrie Stoeken‐Rijsbergen, Willem Verduijn, A. Roos, Yonghong Li, Jeanine J. Houwing‐Duistermaat, T. Huizinga, René E. M. Toes	2013	40
15	A Genome-Wide Association Study of Circulating Galectin-3 PLoS ONE ·Rudolf A. de Boer, Niek Verweij, Dirk J. van Veldhuisen, Harm-Jan Westra, Stephan J. L. Bakker, Ron T. Gansevoort, Anneke C. Muller Kobold, Wiek H. van Gilst, Lude Franke, Irene Mateo Leach, Pim van der Harst	2012	39
16	Inflammation status modulates the effect of host genetic variation on intestinal gene expression in inflammatory bowel disease Nature Communications ·Shixian Hu, Werna T. Uniken Venema, Harm-Jan Westra, Arnau Vich Vila, Ruggero Barbieri, Michiel Voskuil, Tjasso Blokzijl, Bernadien H. Jansen, Yanni Li, Mark J. Daly, Ramnik J. Xavier, Gerard Dijkstra, Eleonora A. Festen, Rinse K. Weersma	2021	34
17	An epigenome-wide association study identifies multiple DNA methylation markers of exposure to endocrine disruptors Environment International ·Xueling Lu, Eliza Fraszczyk, Thomas P. van der Meer, Martijn van Faassen, Vincent W. Bloks, Ido P. Kema, André P. van Beek, Shuang� Li, Lude Franke, Harm-Jan Westra, Xijin Xu, Xia Huo, Harold Snieder, Bruce H. R. Wolffenbuttel, Jana V. van Vliet‐Ostaptchouk	2020	31
18	An integrative systems genetics approach reveals potential causal genes and pathways related to obesity Genome Medicine ·Lisette J. A. Kogelman, Daria V. Zhernakova, Harm-Jan Westra, Susanna Cirera, Merete Fredholm, Lude Franke, Haja N. Kadarmideen	2015	31
19	IMPACT: Genomic Annotation of Cell-State-Specific Regulatory Elements Inferred from the Epigenome of Bound Transcription Factors The American Journal of Human Genetics ·Tiffany Amariuta, Yang Luo, Steven Gazal, Emma E. Davenport, Bryce van de Geijn, Kazuyoshi Ishigaki, Harm-Jan Westra, Nikola C. Teslovich, Yukinori Okada, Kazuhiko Yamamoto, Alkes L. Price, Soumya Raychaudhuri	2019	30
20	Discovering in vivo cytokine-eQTL interactions from a lupus clinical trial Genome biology ·Emma E. Davenport, Tiffany Amariuta, María Gutiérrez‐Arcelus, Kamil Slowikowski, Harm-Jan Westra, Yang Luo, Ciyue Shen, Deepak A. Rao, Ying Zhang, Stephen Pearson, David von Schack, Jean S. Beebe, Nan Bing, Sally John, Michael S. Vincent, Baohong Zhang, Soumya Raychaudhuri	2018	27

About Harm-Jan Westra

Harm-Jan Westra is a scholar working on Molecular Biology, Genetics, Immunology, Genetics and Epidemiology, having authored 38 papers that have together received 1.9k indexed citations. Recurring topics across this work include Genetic Associations and Epidemiology (13 papers), Bioinformatics and Genomic Networks (10 papers), RNA modifications and cancer (5 papers), Gene expression and cancer classification (4 papers), Single-cell and spatial transcriptomics (3 papers), Genetic and phenotypic traits in livestock (3 papers), Chronic Lymphocytic Leukemia Research (3 papers) and Epigenetics and DNA Methylation (3 papers). The work is most often cited by research in Genetics (825 citations), Cancer Research (312 citations), Immunology (371 citations), Gastroenterology (85 citations) and Molecular Biology (1.0k citations). Harm-Jan Westra has collaborated with scholars based in Netherlands, United States and United Kingdom. Frequent co-authors include Lude Franke, Rudolf S.N. Fehrmann, Cisca Wijmenga, Juha Karjalainen, Tōnu Esko, Soumya Raychaudhuri, Joel N. Hirschhorn, Tune H. Pers, Gerard J. te Meerman and Ritsert C. Jansen. Their work appears in journals such as PLoS Genetics, Nature Communications, Genome biology, Nature Genetics and BMC Genomics.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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Harm-Jan Westra

Harm-Jan Westra's Hit Papers

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About Harm-Jan Westra

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