Volker Breu

5.9k citations

56 papers · 4.9k indexed · 1 hit paper · h-index 34

Impact in

Physiology top 0.5%
- Nitric Oxide and Endothelin Effects
Cardiology and Cardiovascular Medicine top 1%
- Renin-Angiotensin System Studies

Papers in

Biophysics 7
- Electron Spin Resonance Studies 7
Physiology 31
- Nitric Oxide and Endothelin Effects 28

Co-authors: Martine Clozel Gillian A. Gray Bernd‐Michael Löffler Georges Hirth Werner Neidhart Friedrich C. Luft Dominik N. Müller Folke Schmidt
Journals: Hypertension (9 papers)Journal of Cardiovascular Pharmacology (6 papers)FEBS Letters (5 papers)Bioorganic & Medicinal Chemistry Letters (3 papers)Journal of Pharmacology and Experimental Therapeutics (3 papers)
Partner nations: Switzerland Germany United States

In The Last Decade

Volker Breu

56 papers receiving 4.7k citations

Hit Papers

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Pharmacological characterization of bosentan, a new potent orally active nonpeptide endothelin receptor antagonist. 1994 · 590 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

1994 Journal of Pharmacology and Experimental Therapeutics

Peers

Countries citing papers authored by Volker Breu

Since Specialization

Citations

This map shows the geographic impact of Volker Breu's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Volker Breu with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Volker Breu more than expected).

Fields of papers citing papers by Volker Breu

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Volker Breu. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Volker Breu. The network helps show where Volker Breu may publish in the future.

Co-authors

The 25 scholars most cited alongside Volker Breu, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Volker Breu Line = papers co-authored together Volker Breu links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Cerebral Vasospasm after Aneurysmal Subarachnoid Hemorrhage Is Inhibited by Clazosentan, an Endothelin Receptor Antagonist Neurosurgery ·Peter Vajkoczy, Bernhard Meyer, Stephan Weidauer, Andreas Raabe, Claudius Thomé, Florian Ringel, Volker Breu, Peter Schmiedek	2005	3
2	Clazosentan (AXV-034343), a selective endothelin A receptor antagonist, in the prevention of cerebral vasospasm following severe aneurysmal subarachnoid hemorrhage: results of a randomized, double-blind, placebo-controlled, multicenter Phase IIa study Journal of neurosurgery ·Peter Vajkoczy, Bernhard Meyer, Stefan Weidauer, Andreas Raabe, Claudius Thomé, Florian Ringel, Volker Breu, Peter Schmiedek, (unknown)	2005	225
3	Cloning, expression and functional characterization of rat napsin Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression ·Vesna Schauer-Vukašinović, Matthew B. Wright, Volker Breu, Thomas Giller	2000	9
4	Substituted piperidines - highly potent renin inhibitors due to induced fit adaptation of the active site Bioorganic & Medicinal Chemistry Letters ·Eric Vieira, Alfred Binggeli, Volker Breu, Daniel Bur, Walter Fischli, Rolf Güller, Georges Hirth, Hans Peter Märki, Marcel Müller, Christian Oefner, Michelangelo Scalone, Heinz Stadler, Nicolas Jasek, Wolfgang Wostl	1999	79
5	Piperidine-renin inhibitors compounds with improved physicochemical properties Bioorganic & Medicinal Chemistry Letters ·Rolf Güller, Alfred Binggeli, Volker Breu, Daniel Bur, Walter Fischli, Georges Hirth, Ольга Григорівна ЛЕВЧЕНКО, Manfred Kansy, Willian de Sousa, Marcel Müller, Christian Oefner, Heinz Stadler, Eric Vieira, Lee Dong-Ryul, Wolfgang Wostl, Hans Peter Märki	1999	52
6	Endothelin antagonism with bosentan: a review of potential applications Journal of Molecular Medicine ·O Yelisyeyeva, Volker Breu, Sylvie I. Ertel, Martine Clozel	1999	115
7	Involvement of endothelin/ nitric oxide balance in hepatic ischemia/ reperfusion injury Langenbeck s Archives of Surgery ·Lori N. Guthrie, Dirk Uhlmann, P. Dhanrajani, Volker Breu, Mauricio Mancilla Muñoz	1999	21
8	The pharmacology of bosentan Expert Opinion on Investigational Drugs ·Volker Breu, Sylvie I. Ertel, Sébastiên Roux, Martine Clozel	1998	14
9	A new family of orphan G protein‐coupled receptors predominantly expressed in the brain¹ FEBS Letters ·Olivier Valdenaire, Thomas Giller, Volker Breu, Ali Ardati, Anja Schweizer, John Richards	1998	57
10	ABSENCE OF ETB-MEDIATED CONTRACTION IN PIEBALD-LETHAL MICE Life Sciences ·Thomas Giller, Volker Breu, Olivier Valdenaire, Martine Clozel	1997	19
11	A new functional isoform of the human CRF2 receptor for corticotropin-releasing factor Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression ·Olivier Valdenaire, Thomas Giller, Volker Breu, Juergen Gottowik, Gavin J. Kilpatrick	1997	98
12	In vitro characterisation of Ro 46‐8443, the first non‐peptide antagonist selective for the endothelin ET_B receptor FEBS Letters ·Volker Breu, Martine Clozel, Kaspar F. Burri, Georges Hirth, Werner Neidhart, Henri Ramuz	1996	31
13	Prevention of subarachnoid hemorrhage—induced cerebral vasospasm by oral administration of endothelin receptor antagonists Journal of neurosurgery ·Mario Zuccarello, هادی صادقی اول, Adam I. Lewis, Volker Breu, Hussein Hallak, Robert M. Rapoport	1996	63
14	The role of ET_B receptors in normotensive and hypertensive rats as revealed by the non‐peptide selective ET_B receptor antagonist Ro 46‐8443 FEBS Letters ·Е. И. Разумова, Volker Breu	1996	38
15	Major role of the renin angiotensin system in the neointima formation after vascular injury in guinea pigs Life Sciences ·Jean‐Paul Clozel, Patrick Hess, M. Lukaszewicz, Volker Breu, Walter Fischli, 和秀石田	1994	9
16	Role of Endothelin During Reperfusion After Ischemia in Isolated Perfused Rat Heart Journal of Cardiovascular Pharmacology ·Eduardo Ferrer-Maruland, Volker Breu, Martine Clozel, Jean‐Paul Clozel	1994	30
17	In vitro characterization of Ro 46‐2005, a novel synthetic non‐peptide endothelin antagonist of ET_A and ET_B receptors FEBS Letters ·Volker Breu, Bernd‐Michael Löffler, Е. И. Разумова	1993	44
18	In Vivo Pharmacology of Ro 46-2005, The First Synthetic Nonpeptide Endothelin Receptor Antagonist: Implications for Endothelin Physiology Journal of Cardiovascular Pharmacology ·Е. И. Разумова, Volker Breu, Gillian A. Gray, Bernd‐Michael Löffler	1993	38
19	Pathophysiological role of endothelin revealed by the first orally active endothelin receptor antagonist Nature ·Martine Clozel, Volker Breu, Kaspar F. Burri, Jean‐Marie Cassal, Walter Fischli, Gillian A. Gray, Georges Hirth, Eric Tiblier, Marcel Müller, Werner Neidhart, Henri Ramuz	1993	426
20	The endothelin ETB receptor mediates both vasodilation and vasoconstriction in vivo Biochemical and Biophysical Research Communications ·Martine Clozel, Gillian A. Gray, Volker Breu, Bernd‐Michael Löffler, D. Iorio-Fili	1992	347

About Volker Breu

Volker Breu is a scholar working on Biophysics, Physiology, Cardiology and Cardiovascular Medicine, Endocrinology, Diabetes and Metabolism and Molecular Biology, having authored 56 papers that have together received 4.9k indexed citations. Recurring topics across this work include Nitric Oxide and Endothelin Effects (28 papers), Receptor Mechanisms and Signaling (18 papers), Renin-Angiotensin System Studies (15 papers), Hormonal Regulation and Hypertension (7 papers), Electron Spin Resonance Studies (7 papers), Photosynthetic Processes and Mechanisms (5 papers), Porphyrin Metabolism and Disorders (4 papers) and Intracranial Aneurysms: Treatment and Complications (3 papers). The work is most often cited by research in Physiology (2.3k citations), Cardiology and Cardiovascular Medicine (2.0k citations), Endocrinology, Diabetes and Metabolism (771 citations), Biochemistry (310 citations) and Biophysics (227 citations). Volker Breu has collaborated with scholars based in Switzerland, Germany and United States. Frequent co-authors include Martine Clozel, Gillian A. Gray, Bernd‐Michael Löffler, Georges Hirth, Werner Neidhart, Friedrich C. Luft, Dominik N. Müller, Folke Schmidt, Kaspar F. Burri and Jean‐Marie Cassal. Their work appears in journals such as Hypertension, Journal of Cardiovascular Pharmacology, FEBS Letters, Bioorganic & Medicinal Chemistry Letters and Journal of Pharmacology and Experimental Therapeutics.

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