Frederick Peter Guengerich

89.8k citations
1.1k papers · 83.3k · 31 hit papers · h-index 137

Impact in

  • Pharmacology top 0.01%
    • Pharmacogenetics and Drug Metabolism
    • Drug-Induced Hepatotoxicity and Protection
    • Carcinogens and Genotoxicity Assessment

Papers in

Frederick Peter Guengerich

1.1k papers receiving 78.3k citations

Frederick Peter Guengerich's Hit Papers

Structural analyses of Candida albicans sterol 14α-demethylase complexed with azole drugs address the molecular basis of azole-mediated inhibition of fungal sterol biosynthesis 2017 · 358 citations
3580+11+23Years since publication50010001.5k2.0k

Peers

Frederick Peter Guengerich
Comparison fields: 5 of 154
  • Pharmacology 34.0k
  • Cancer Research 4.3k
  • Inorganic Chemistry 3.9k
  • Biochemistry 703
  • Molecular Biology 8.5k
Replace Frank J. Gonzalez with:
Frank J. Gonzalez United States
Magnus Ingelman‐Sundberg Sweden
Daniel W. Nebert United States
C. Roland Wolf United Kingdom
David J. Waxman United States
Bharat Bhushan Aggarwal United States
Allan H. Conney United States
Ronald Paul Mason United States
Minor J. Coon United States
Helmut Sies Germany
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Citations per field
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Frank J. Gonzalez · 1×
Citations per year

Countries citing papers authored by Frederick Peter Guengerich

Since Specialization
Citations

This map shows the geographic impact of Frederick Peter Guengerich's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Frederick Peter Guengerich with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Frederick Peter Guengerich more than expected).

Fields of papers citing papers by Frederick Peter Guengerich

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Frederick Peter Guengerich. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Frederick Peter Guengerich. The network helps show where Frederick Peter Guengerich may publish in the future.

Co-authors

The 25 scholars most cited alongside Frederick Peter Guengerich, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Frederick Peter Guengerich Line = papers co-authored together Frederick Peter Guengerich links everyone, so they are left out of the graph.

All Works

20 of 20 papers shown

Showing the 20 most-cited of 1.1k papers — load more, or switch the sort, to bring in the rest.

#Work
1
Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.
Hit paper breakdown →
19942455
2
The P450 Superfamily: Update on New Sequences, Gene Mapping, Accession Numbers, Early Trivial Names of Enzymes, and Nomenclature
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19931457
3
Common and Uncommon Cytochrome P450 Reactions Related to Metabolism and Chemical Toxicity
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20011386
4
Cytochrome P450 and Chemical Toxicology
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20071361
5
CYTOCHROME P-450 3A4: Regulation and Role in Drug Metabolism
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19991102
6
Role of human cytochrome P-450 IIE1 in the oxidation of many low molecular weight cancer suspects
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19911065
7
The P450 Superfamily: Update on New Sequences, Gene Mapping, and Recommended Nomenclature
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1991979
8
Purification and characterization of liver microsomal cytochromes P-450: electrophoretic, spectral, catalytic, and immunochemical properties and inducibility of eight isozymes isolated from rats treated with phenobarbital or .beta.-naphthoflavone
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1982969
9
Oxidation of toxic and carcinogenic chemicals by human cytochrome P-450 enzymes
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1991901
10
Mapping the Genetic Architecture of Gene Expression in Human Liver
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2008781
11
The P450 Gene Superfamily: Recommended Nomenclature
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1987711
12
Activation of chemically diverse procarcinogens by human cytochrome P-450 1B1.
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1996698
13
Characterization of rat and human liver microsomal cytochrome P-450 forms involved in nifedipine oxidation, a prototype for genetic polymorphism in oxidative drug metabolism.
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1986686
14
Human Cytochrome P450 Enzymes
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1995668
15
Dealkylation of pentoxyresorufin: A rapid and sensitive assay for measuring induction of cytochrome(s) P-450 by phenobarbital and other xenobiotics in the rat
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1985618
16
Human cytochrome P-450PA (P-450IA2), the phenacetin O-deethylase, is primarily responsible for the hepatic 3-demethylation of caffeine and N-oxidation of carcinogenic arylamines.
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1989578
17
The P450 Superfamily: Updated Listing of All Genes and Recommended Nomenclature for the Chromosomal Loci
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1989564
18
Regulation of rat hepatic cytochrome P-450: age-dependent expression, hormonal imprinting, and xenobiotic inducibility of sex-specific isoenzymes
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1985561
19
Reactions and significance of cytochrome P-450 enzymes
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1991524
20
Hydroxylation of chlorzoxazone as a specific probe for human liver cytochrome P-450IIE1
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1990504

About Frederick Peter Guengerich

Frederick Peter Guengerich is a scholar working on Pharmacology, Inorganic Chemistry, Cancer Research, Molecular Biology and Food Science, having authored 1.1k papers that have together received 83.3k indexed citations. Recurring topics across this work include Pharmacogenetics and Drug Metabolism (519 papers), DNA Repair Mechanisms (80 papers), Metal-Catalyzed Oxygenation Mechanisms (73 papers), Carcinogens and Genotoxicity Assessment (65 papers), DNA and Nucleic Acid Chemistry (16 papers), Agricultural safety and regulations (14 papers), Glutathione Transferases and Polymorphisms (12 papers) and Mycotoxins in Agriculture and Food (11 papers). The work is most often cited by research in Pharmacology (34.0k citations), Cancer Research (4.3k citations), Inorganic Chemistry (3.9k citations), Biochemistry (703 citations) and Molecular Biology (8.5k citations). Frederick Peter Guengerich has collaborated with scholars based in United States, Japan and South Korea. Frequent co-authors include Tsutomu Shimada, Hiroshi Yamazaki, Ghazi A. Dannan, David J. Waxman, Martha V. Martin, Chul‐Ho Yun, Yukiharu Inui, Elizabeth M. J. Gillam, Mayumi Mimura and Laurence S. Kaminsky. Their work appears in journals such as Journal of Biological Chemistry, Chemical Research in Toxicology, Biochemistry, Archives of Biochemistry and Biophysics and Drug Metabolism and Disposition.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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