Fred C. Lam

2.7k citations

64 papers · 1.8k indexed · h-index 18

Impact in

Biological Psychiatry top 10%
Biomaterials top 10%
- Nanoparticle-Based Drug Delivery

Papers in ⓘ

Surgery 19
- Management of metastatic bone disease 5
Molecular Biology 16
- DNA Repair Mechanisms 4

Co-authors: Peter B. Reiner (2 shared papers)Michael B. Yaffe (4 shared papers)Peihua Lu (1 shared paper)Adam B. Shapiro (1 shared paper)Jack‐Michel Renoir (1 shared paper)Frances J. Sharom (1 shared paper)Amanda Maffa (2 shared papers)Ekkehard Kasper (1 shared paper)
Journals: Nature Communications (3 papers)Journal of Neurosurgery Spine (3 papers)The Journal of Clinical Pharmacology (3 papers)Emergency Medicine Journal (2 papers)Frontiers in Bioengineering and Biotechnology (2 papers)
Partner nations: United States Canada New Zealand

In The Last Decade

Fred C. Lam

51 papers receiving 1.8k citations

Peers

Countries citing papers authored by Fred C. Lam

Since Specialization

Citations

This map shows the geographic impact of Fred C. Lam's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Fred C. Lam with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Fred C. Lam more than expected).

Fields of papers citing papers by Fred C. Lam

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Fred C. Lam. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Fred C. Lam. The network helps show where Fred C. Lam may publish in the future.

Co-authors

The 25 scholars most cited alongside Fred C. Lam, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Fred C. Lam Line = papers co-authored together Fred C. Lam links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 64 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	β‐Amyloid efflux mediated by p‐glycoprotein Journal of Neurochemistry ·Fred C. Lam, Ronghua Liu, Peihua Lu, Adam B. Shapiro, Jack‐Michel Renoir, Frances J. Sharom, Peter B. Reiner	2001	313
2	The DNA-sensing AIM2 inflammasome controls radiation-induced cell death and tissue injury Science ·Bo Hu, Chengcheng Jin, Huabing Li, Jiyu Tong, Xinshou Ouyang, Naniye Mallı Cetinbas, Shu Zhu, Till Strowig, Fred C. Lam, Chen Zhao, Jorge Henao‐Mejia, Ömer Yılmaz, Katherine A. Fitzgerald, Stephanie C. Eisenbarth, Eran Elinav, Richard A. Flavell	2016	303
3	Enhanced efficacy of combined temozolomide and bromodomain inhibitor therapy for gliomas using targeted nanoparticles Nature Communications ·Fred C. Lam, Stephen W. Morton, Jeffrey Wyckoff, Tu-Lan Vu Han, Mun Kyung Hwang, Amanda Maffa, Elena Balkanska-Sinclair, Michael B. Yaffe, Scott Floyd, Paula T. Hammond	2018	276
4	Regulation of Amyloid Precursor Protein Catabolism Involves the Mitogen-Activated Protein Kinase Signal Transduction Pathway Journal of Neuroscience ·Julia Mills, David L. Charest, Fred C. Lam, Konrad Beyreuther, Nobuo Ida, Steven Pelech, Peter B. Reiner	1997	121
5	BRD4 prevents the accumulation of R-loops and protects against transcription–replication collision events and DNA damage Nature Communications ·Fred C. Lam, Yi Wen Kong, Qiuying Huang, Tu-Lan Vu Han, Amanda Maffa, Ekkehard M. Kasper, Michael B. Yaffe	2020	107
6	Area method for the estimation of partition coefficients for physiological pharmacokinetic models Journal of Pharmacokinetics and Biopharmaceutics ·James M. Gallo, Fred C. Lam, Donald Perrier	1987	73
7	Augmented Autologous Pericranium Duraplasty in 100 Posterior Fossa Surgeries—A Retrospective Case Series Operative Neurosurgery ·Fred C. Lam, Ekkehard Kasper	2012	59
8	Ascending-dose study of noribogaine in healthy volunteers: Pharmacokinetics, pharmacodynamics, safety, and tolerability The Journal of Clinical Pharmacology ·Paul Glue, Michelle Lockhart, Fred C. Lam, Noelyn Hung, Cheung‐Tak Hung, Lawrence Friedhoff	2014	47
9	Ascending Single‐Dose, Double‐Blind, Placebo‐Controlled Safety Study of Noribogaine in Opioid‐Dependent Patients Clinical Pharmacology in Drug Development ·Paul Glue, Gavin Cape, Donna Tunnicliff, Michelle Lockhart, Fred C. Lam, Noelyn Hung, Cheung‐Tak Hung, Sarah Harland, Jane Devane, R. S. Crockett, John F. Howes, Börje Darpö, Meijian Zhou, Holger Weis, Lawrence Friedhoff	2016	45
10	Phage Particles of Controlled Length and Genome for In Vivo Targeted Glioblastoma Imaging and Therapeutic Delivery ACS Nano ·Uyanga Tsedev, Ching‐Wei Lin, Gaelen T. Hess, Jann N. Sarkaria, Fred C. Lam, Angela M. Belcher	2022	43
11	Antibody-targeting of ultra-small nanoparticles enhances imaging sensitivity and enables longitudinal tracking of multiple myeloma Nanoscale ·Alexandre Detappe, Mairéad Reidy, Yingjie Yu, C. Mathieu, Hung V.‐T. Nguyen, Thibaud Coroller, Fred C. Lam, Petr Jarolı́m, Peter Harvey, Andrea Protti, Quang‐Dé Nguyen, Jeremiah A. Johnson, Yannick Crémillieux, Olivier Tillement, Irene M. Ghobrial, P. Peter Ghoroghchian	2019	31
12	A new technique for reduction of prolapsed fetal membranes for emergency cervical cerclage. PubMed ·L Scheerer, Fred C. Lam, L Bartolucci, M Katz	1989	26
13	Enhancing chemotherapy response through augmented synthetic lethality by co-targeting nucleotide excision repair and cell-cycle checkpoints Nature Communications ·Yi Wen Kong, Erik C. Dreaden, Sandra Morandell, Wen Zhou, Sanjeev Dhara, Ganapathy Sriram, Fred C. Lam, Jesse C. Patterson, Mohiuddin Quadir, Anh Dinh, Kevin E. Shopsowitz, Shohreh Varmeh, Ömer Yılmaz, Stephen J. Lippard, Hans Christian Reinhardt, Michael T. Hemann, Paula T. Hammond, Michael B. Yaffe	2020	24
14	Safety and efficacy of extended release ketamine tablets in patients with treatment-resistant depression and anxiety: open label pilot study SHILAP Revista de lepidopterología ·Paul Glue, Natalie J. Medlicott, Shona Neehoff, Peter Surman, Fred C. Lam, Noelyn Hung, Cheung‐Tak Hung	2020	24
15	Poly (I:C) therapy decreases cerebral ischaemia/reperfusion injury via TLR3‐mediated prevention of Fas/FADD interaction Journal of Cellular and Molecular Medicine ·Xia Zhang, Tuanzhu Ha, Chen Lu, Fred C. Lam, Li Liu, John B. Schweitzer, John H. Kalbfleisch, Race L. Kao, David L. Williams, Chuanfu Li	2014	23
16	A comprehensive literature review and meta‐analysis of the prevalence of pan‐cancer BRCA mutations, homologous recombination repair gene mutations, and homologous recombination deficiencies Environmental and Molecular Mutagenesis ·Changxia Shao, Jun Wan, Fred C. Lam, Huilin Tang, Andrew R. Marley, Yiqing Song, Chelsey Miller, Madeline Brown, Jiali Han, Gboyega Adeboyeje	2022	23
17	Nicotine Increases Impulsivity and Decreases Willingness to Exert Cognitive Effort despite Improving Attention in “Slacker” Rats: Insights into Cholinergic Regulation of Cost/Benefit Decision Making PLoS ONE ·Jay G. Hosking, Fred C. Lam, Catharine A. Winstanley	2014	21
18	The DNA damage response - from cell biology to human disease Fred C. Lam	2022	17
19	The Effects of Design and Positioning of Carbon Fiber Lumbar Interbody Cages and Their Subsidence in Vertebral Bodies Journal of Spinal Disorders & Techniques ·Fred C. Lam, Ron N. Alkalay, Michael W. Groff	2011	16
20	Current Treatment Approaches and Global Consensus Guidelines for Brain Metastases in Melanoma Frontiers in Oncology ·Xiang‐Lin Tan, Amy Le, Fred C. Lam, Emilie Scherrer, Robert Kerr, Anthony Lau, Jiali Han, Ruixuan Jiang, Scott J. Diede, Irene M. Shui	2022	13

About Fred C. Lam

Fred C. Lam is a scholar working on Surgery, Molecular Biology, Neurology, Genetics and Pulmonary and Respiratory Medicine, having authored 64 papers that have together received 1.8k indexed citations. Recurring topics across this work include Glioma Diagnosis and Treatment (10 papers), Brain Metastases and Treatment (9 papers), Meningioma and schwannoma management (7 papers), Neurofibromatosis and Schwannoma Cases (7 papers), Management of metastatic bone disease (5 papers), Vascular Malformations Diagnosis and Treatment (4 papers), DNA Repair Mechanisms (4 papers) and Spine and Intervertebral Disc Pathology (4 papers). The work is most often cited by research in Biological Psychiatry (37 citations), Biomaterials (182 citations), Oncology (363 citations), Cellular and Molecular Neuroscience (215 citations) and Neurology (93 citations). Fred C. Lam has collaborated with scholars based in United States, Canada and New Zealand. Frequent co-authors include Peter B. Reiner, Michael B. Yaffe, Peihua Lu, Adam B. Shapiro, Jack‐Michel Renoir, Frances J. Sharom, Amanda Maffa, Ekkehard Kasper, Paula T. Hammond and Jeffrey Wyckoff. Their work appears in journals such as Nature Communications, Journal of Neurosurgery Spine, The Journal of Clinical Pharmacology, Emergency Medicine Journal and Frontiers in Bioengineering and Biotechnology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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