Frances J. Sharom

10.3k citations

140 papers · 8.7k indexed · 3 hit papers · h-index 50

Oncology top 0.2%
- Drug Transport and Resistance Mechanisms 73
Pediatrics, Perinatology and Child Health top 0.5%
- Pharmacological Effects and Toxicity Studies 20
Molecular Biology top 1%
- Lipid Membrane Structure and Behavior 36
- Glycosylation and Glycoproteins Research 24
- Protein Interaction Studies and Fluorescence Analysis 17
- DNA and Nucleic Acid Chemistry 11
Molecular Medicine top 2%
Infectious Diseases top 1%
- HIV/AIDS drug development and treatment 14
Pharmacology
- Antibiotics Pharmacokinetics and Efficacy 12

Co-authors: Paul D. W. Eckford Ronghua Liu Carl A. Doige Yolanda Romsicki Peihua Lu Xiaohong Yu Chris W.M. Grant Joseph W.K. Chu
Cited by: Oncology Pediatrics, Perinatology and Child Health Molecular Biology
Partner nations: Canada United States Venezuela

In The Last Decade

Frances J. Sharom

139 papers receiving 8.5k citations

Hit Papers

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What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

2011 The P-glycoprotein multidrug transporter
2009 ABC Efflux Pump-Based Resistance to Chemotherapy Drugs
2007 ABC Multidrug Transporters: Structure, Function and Role in Chemoresistance

Peers

Countries citing papers authored by Frances J. Sharom

Since Specialization

Citations

This map shows the geographic impact of Frances J. Sharom's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Frances J. Sharom with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Frances J. Sharom more than expected).

Fields of papers citing papers by Frances J. Sharom

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Frances J. Sharom. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Frances J. Sharom. The network helps show where Frances J. Sharom may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Frances J. Sharom, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Frances J. Sharom Line = papers co-authored together Frances J. Sharom links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	A semisynthetic taxane Yg-3-46a effectively evades P-glycoprotein and β-III tubulin mediated tumor drug resistance in vitro Pei Cai,Peihua Lu,Frances J. Sharom,Wei‐Shuo Fang	2013	18
2	Synthesis and evaluation of Strychnos alkaloids as MDR reversal agents for cancer cell eradication Surendrachary Munagala,Gopal Sirasani,Praveen Kokkonda,Manali Phadke,Natalia F. Krynetskaia,Peihua Lu,Frances J. Sharom,Sidhartha Chaudhury,Mohamed Diwan M. AbdulHameed,Gregory J. Tawa,Anders Wallqvist,Rogelio L. Martinez,Wayne E. Childers,Magid Abou‐Gharbia,Evgeny Krynetskiy,Rodrigo Andrade	2013	29
3	Essays In Biochemistry: 50 Frances J. Sharom	2011	1
4	Transient Kinetics of Nucleotide Binding to the P-glycoprotein Multidrug Transporter Miguel R. Lugo,Joseph W.K. Chu,Frances J. Sharom	2011	1
5	Effects of C7 substitutions in a high affinity microtubule-binding taxane on antitumor activity and drug transport Xi Xiao,Wu Ju,Chiara Trigili,Hui Chen,Joseph W.K. Chu,Ying Zhao,Peihua Lu,Sheng Li,Yan Li,Frances J. Sharom,Isabel Barasoaı́n,J. Fernando Dı́az,Wei‐Shuo Fang	2011	8
6	Fluorescence Studies of Drug Binding and Translocation by Membrane Transporters Frances J. Sharom,Ronghua Liu,Balpreet Vinepal	2010	7
7	Interaction of insecticides with mammalian P-glycoprotein and their effect on its transport function K. Sreeramulu,Ronghua Liu,Frances J. Sharom	2007	41
8	P‐Glycoprotein is localized in intermediate‐density membrane microdomains distinct from classical lipid rafts and caveolar domains Galina Radeva,Jocelyne Perabo,Frances J. Sharom	2005	55
9	New Insights into the Drug Binding, Transport and Lipid Flippase Activities of the P-Glycoprotein Multidrug Transporter Frances J. Sharom,Miguel R. Lugo,Paul D. W. Eckford	2005	32
10	Celastraceae Sesquiterpenes as a New Class of Modulators That Bind Specifically to Human P-Glycoprotein and Reverse Cellular Multidrug Resistance Francisco Muñoz‐Martínez,Peihua Lu,Fernando Cortés-Selva,José M. Pérez‐Victoria,Ignacio A. Jiménez,Ángel G. Ravelo,Frances J. Sharom,Francisco Gamarro,Santiago Castanys	2004	73
11	Comparison of proto‐oncogenic and mutant forms of the transmembrane region of the Neu receptor in TFE R. Scott Houliston,Robert S. Hodges,Frances J. Sharom,James H. Davis	2002	14
12	Exploring the structure and function of the P-glycoprotein multidrug transporter using fluorescence spectroscopic tools Frances J. Sharom,Ronghua Liu,Qin Qu,Yolanda Romsicki	2001	51
13	β‐Amyloid efflux mediated by p‐glycoprotein Fred C. Lam,Ronghua Liu,Peihua Lu,Adam B. Shapiro,Jack‐Michel Renoir,Frances J. Sharom,Peter B. Reiner	2001	313
14	Insights into the structure and substrate interactions of the P-glycoprotein multidrug transporter from spectroscopic studies Frances J. Sharom,Ronghua Liu,Yolanda Romsicki,Peihua Lu	1999	77
15	Spectroscopic and biophysical approaches for studying the structure and function of the P-glycoprotein multidrug transporter Frances J. Sharom,Ronghua Liu,Yolanda Romsicki	1998	2
16	The P-Glycoprotein Efflux Pump: How Does it Transport Drugs? Frances J. Sharom	1997	388
17	Effect of micellar and bilayer gangliosides on proliferation of interleukin-2-dependent lymphocytes Joseph W.K. Chu,Frances J. Sharom	1991	15
18	Interleukin-2 binds to gangliosides in micelles and lipid bilayers Joseph W.K. Chu,Frances J. Sharom	1990	20
19	Interaction of Concanavalin A and a Divalent Derivative with Lymphocytes and Reconstituted Lymphocyte Membrane Glycoproteins Frances J. Sharom,Susan Head,Christine C. Kupsh,Lauretta Williams	1989	3
20	Inhibition of lymphocyte 5′-nucleotidase by lectins: effects of lectin specificityand cross-linking ability Frances J. Sharom,Mary P. Lamb,Christine C. Kupsh,Susan Head	1988	4

About Frances J. Sharom

Frances J. Sharom is a scholar working on Oncology, Equine and Molecular Biology, having authored 140 papers that have together received 8.7k indexed citations. Recurring topics across this work include Drug Transport and Resistance Mechanisms (73 papers), Lipid Membrane Structure and Behavior (36 papers), Glycosylation and Glycoproteins Research (24 papers), Pharmacological Effects and Toxicity Studies (20 papers), Protein Interaction Studies and Fluorescence Analysis (17 papers), HIV/AIDS drug development and treatment (14 papers), Antibiotics Pharmacokinetics and Efficacy (12 papers) and DNA and Nucleic Acid Chemistry (11 papers). The work is most often cited by research in Oncology (5.2k citations), Pediatrics, Perinatology and Child Health (1.5k citations) and Molecular Biology (4.5k citations). Frances J. Sharom has collaborated with scholars based in Canada, United States and Venezuela. Frequent co-authors include Paul D. W. Eckford, Ronghua Liu, Carl A. Doige, Yolanda Romsicki, Peihua Lu, Xiaohong Yu, Chris W.M. Grant, Joseph W.K. Chu, Xin Yu and Marty T. Lehto.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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