Eric B. Springman

1.5k total citations · 1 hit paper
25 papers, 1.1k citations indexed

About

Eric B. Springman is a scholar working on Molecular Biology, Genetics and Organic Chemistry. According to data from OpenAlex, Eric B. Springman has authored 25 papers receiving a total of 1.1k indexed citations (citations by other indexed papers that have themselves been cited), including 9 papers in Molecular Biology, 7 papers in Genetics and 5 papers in Organic Chemistry. Recurrent topics in Eric B. Springman's work include Coagulation, Bradykinin, Polyphosphates, and Angioedema (7 papers), Melanoma and MAPK Pathways (6 papers) and Computational Drug Discovery Methods (4 papers). Eric B. Springman is often cited by papers focused on Coagulation, Bradykinin, Polyphosphates, and Angioedema (7 papers), Melanoma and MAPK Pathways (6 papers) and Computational Drug Discovery Methods (4 papers). Eric B. Springman collaborates with scholars based in United States, United Kingdom and Switzerland. Eric B. Springman's co-authors include Harold E. Van Wart, Henning Birkedal‐Hansen, Eddie L. Angleton, Marina Bukhtiyarova, Michael Karpusas, David J. Casper, W E Serafin, B.A. Katz, Beishan Liu and Younghee Lee and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Biochemistry.

In The Last Decade

Eric B. Springman

23 papers receiving 1.1k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Multiple modes of activation of latent human fibroblast collagenase: evidence for the role of a Cys73 active-site zinc complex in latency and a "cysteine switch" mechanism for activation.

1990 577 citations Eric B. Springman, Eddie L. Angleton et al. Proceedings of the National Academy of Sciences profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Eric B. Springman United States	15	479	434	348	234	142	25	1.1k
Maureen H. Beresini United States	22	560 1.2×	168 0.4×	200 0.6×	114 0.5×	41 0.3×	34	1.2k
Didier Belorgey United Kingdom	23	529 1.1×	458 1.1×	200 0.6×	185 0.8×	59 0.4×	34	1.1k
Michelle L. Kraus United States	7	466 1.0×	129 0.3×	447 1.3×	145 0.6×	68 0.5×	9	1.1k
Ilaria Laurenzana Italy	22	962 2.0×	523 1.2×	180 0.5×	267 1.1×	174 1.2×	55	1.4k
E. Ahn United States	22	869 1.8×	262 0.6×	210 0.6×	193 0.8×	67 0.5×	55	1.4k
Andrea Schweinitz Germany	13	299 0.6×	230 0.5×	151 0.4×	141 0.6×	54 0.4×	23	620
Rama Kannan United States	15	446 0.9×	344 0.8×	330 0.9×	143 0.6×	119 0.8×	22	1.0k
Joseph W. Leone United States	17	888 1.9×	103 0.2×	267 0.8×	104 0.4×	61 0.4×	38	1.5k
Robert Wieder United States	25	907 1.9×	343 0.8×	569 1.6×	81 0.3×	104 0.7×	66	1.6k
Vanessa C. Gray‐Schopfer United Kingdom	7	1.3k 2.7×	195 0.4×	733 2.1×	87 0.4×	46 0.3×	8	1.9k

Countries citing papers authored by Eric B. Springman

Since Specialization

Citations

This map shows the geographic impact of Eric B. Springman's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Eric B. Springman with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Eric B. Springman more than expected).

Fields of papers citing papers by Eric B. Springman

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Eric B. Springman. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Eric B. Springman. The network helps show where Eric B. Springman may publish in the future.

Co-authorship network of co-authors of Eric B. Springman

This figure shows the co-authorship network connecting the top 25 collaborators of Eric B. Springman. A scholar is included among the top collaborators of Eric B. Springman based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Eric B. Springman. Eric B. Springman is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Levitt, Joseph E., Haley Hedlin, Di Lu, et al.. (2023). Evaluation of Acebilustat, a Selective Inhibitor of Leukotriene B4 Biosynthesis, for Treatment of Outpatients With Mild-Moderate Coronavirus Disease 2019: A Randomized, Double-Blind, Placebo-Controlled Phase 2 Trial. Clinical Infectious Diseases. 77(2). 186–193.

Elborn, J.S., Michael W. Konstan, Jennifer L. Taylor‐Cousar, et al.. (2021). Empire-CF study: A phase 2 clinical trial of leukotriene A4 hydrolase inhibitor acebilustat in adult subjects with cystic fibrosis. Journal of Cystic Fibrosis. 20(6). 1026–1034. 11 indexed citations

Bunning, Bryan, Haley Hedlin, Natasha Purington, et al.. (2021). The COVID-19 Outpatient Pragmatic Platform Study (COPPS): Study design of a multi-center pragmatic platform trial. Contemporary Clinical Trials. 108. 106509–106509. 4 indexed citations

Margaroli, Camilla, Cecilia Thompson, Milton R. Brown, et al.. (2020). Distinct compartmentalization of immune cells and mediators characterizes bullous pemphigoid disease. Experimental Dermatology. 29(12). 1191–1198. 12 indexed citations

Margaroli, Camilla, Bekh Bradley, Sanjeev Ahuja, et al.. (2019). 1034 Leukotriene B4 pathway and tissue damage markers are expressed by granulocytes in lesional skin in bullous pemphigoid. Journal of Investigative Dermatology. 139(5). S179–S179.

Elborn, J.S., Sanjeev Ahuja, Eric B. Springman, et al.. (2018). EMPIRE-CF: A phase II randomized placebo-controlled trial of once-daily, oral acebilustat in adult patients with cystic fibrosis – Study design and patient demographics. Contemporary Clinical Trials. 72. 86–94. 25 indexed citations

Gardner, Erin R., Martha J. Kelly, Eric B. Springman, et al.. (2010). Antiangiogenic and antitumor activity of LP-261, a novel oral tubulin binding agent, alone and in combination with bevacizumab. Investigational New Drugs. 30(1). 90–97. 4 indexed citations

Liu, Bin, Younghee Lee, H. Michael Petrassi, et al.. (2010). Discovery and SAR of a series of 4,6-diamino-1,3,5-triazin-2-ol as novel non-nucleoside reverse transcriptase inhibitors of HIV-1. Bioorganic & Medicinal Chemistry Letters. 20(22). 6592–6596. 17 indexed citations

Bukhtiyarova, Marina, et al.. (2010). Analysis of Imatinib and Sorafenib Binding to p38α Compared with c-Abl and b-Raf Provides Structural Insights for Understanding the Selectivity of Inhibitors Targeting the DFG-Out Form of Protein Kinases. Biochemistry. 49(17). 3611–3618. 58 indexed citations

10.

Liu, Bin, et al.. (2009). Structure-based design of substituted biphenyl ethylene ethers as ligands binding in the hydrophobic pocket of gp41 and blocking the helical bundle formation. Bioorganic & Medicinal Chemistry Letters. 19(19). 5693–5697. 12 indexed citations

11.

Michelotti, Enrique L., Martha J. Kelly, Xiaomei Chai, et al.. (2005). Two classes of p38α MAP kinase inhibitors having a common diphenylether core but exhibiting divergent binding modes. Bioorganic & Medicinal Chemistry Letters. 15(23). 5274–5279. 29 indexed citations

12.

Tang, Jie, Christine Yu, Steven R. Williams, et al.. (2005). Expression, Crystallization, and Three-dimensional Structure of the Catalytic Domain of Human Plasma Kallikrein. Journal of Biological Chemistry. 280(49). 41077–41089. 60 indexed citations

13.

Bukhtiyarova, Marina, et al.. (2004). Improved expression, purification, and crystallization of p38α MAP kinase. Protein Expression and Purification. 37(1). 154–161. 39 indexed citations

14.

Casper, David J., Marina Bukhtiyarova, & Eric B. Springman. (2003). A Biacore biosensor method for detailed kinetic binding analysis of small molecule inhibitors of p38α mitogen-activated protein kinase. Analytical Biochemistry. 325(1). 126–136. 50 indexed citations

15.

Broka, Chris A., Robert L. Martin, Christine Chan, et al.. (2002). Amino acid derived sulfonamide hydroxamates as inhibitors of procollagen C-Proteinase. Part 2: Solid-Phase optimization of side chains. Bioorganic & Medicinal Chemistry Letters. 12(8). 1233–1235. 12 indexed citations

16.

Katz, B.A., et al.. (1998). Crystal structure of recombinant human tissue kallikrein at 2.0 Å resolution. Protein Science. 7(4). 875–885. 43 indexed citations

17.

Springman, Eric B., et al.. (1998). Expression and Characterization of Human Tissue Kallikrein Variants. Protein Expression and Purification. 12(3). 361–370. 14 indexed citations

18.

Springman, Eric B., et al.. (1995). Mast Cell Procarboxypeptidase A. Journal of Biological Chemistry. 270(3). 1300–1307. 21 indexed citations

19.

Springman, Eric B., Hideaki Nagase, Henning Birkedal‐Hansen, & Harold E. Van Wart. (1995). Zinc Content and Function in Human Fibroblast Collagenase. Biochemistry. 34(48). 15713–15720. 16 indexed citations

20.

Springman, Eric B., Eddie L. Angleton, Henning Birkedal‐Hansen, & Harold E. Van Wart. (1990). Multiple modes of activation of latent human fibroblast collagenase: evidence for the role of a Cys73 active-site zinc complex in latency and a "cysteine switch" mechanism for activation.. Proceedings of the National Academy of Sciences. 87(1). 364–368. 577 indexed citations breakdown →

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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