Harold E. Van Wart

7.8k total citations · 2 hit papers
105 papers, 6.4k citations indexed

About

Harold E. Van Wart is a scholar working on Molecular Biology, Cancer Research and Oncology. According to data from OpenAlex, Harold E. Van Wart has authored 105 papers receiving a total of 6.4k indexed citations (citations by other indexed papers that have themselves been cited), including 46 papers in Molecular Biology, 31 papers in Cancer Research and 29 papers in Oncology. Recurrent topics in Harold E. Van Wart's work include Protease and Inhibitor Mechanisms (30 papers), Peptidase Inhibition and Analysis (24 papers) and Enzyme Production and Characterization (15 papers). Harold E. Van Wart is often cited by papers focused on Protease and Inhibitor Mechanisms (30 papers), Peptidase Inhibition and Analysis (24 papers) and Enzyme Production and Characterization (15 papers). Harold E. Van Wart collaborates with scholars based in United States, Switzerland and Canada. Harold E. Van Wart's co-authors include Henning Birkedal‐Hansen, Harold A. Scheraga, Michael D. Bond, Eddie L. Angleton, Eric B. Springman, Kasim A. Mookhtiar, Haesun Kang Baek, Gregg Fields, Satish Mallya and Sarah Netzel–Arnett and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of the American Chemical Society and Journal of Biological Chemistry.

In The Last Decade

Harold E. Van Wart

105 papers receiving 6.0k citations

Hit Papers

The cysteine switch: a pr... 1990 2026 2002 2014 1990 1990 250 500 750 1000
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. The cysteine switch: a principle of regulation of metalloproteinase activity with potential applicability to the entire matrix metalloproteinase gene family.
    1990 1.2k citations Harold E. Van Wart, Henning Birkedal‐Hansen profile →
  2. Multiple modes of activation of latent human fibroblast collagenase: evidence for the role of a Cys73 active-site zinc complex in latency and a "cysteine switch" mechanism for activation.
    1990 577 citations Eric B. Springman, Eddie L. Angleton et al. profile →

Author Peers

Peers are selected by citation overlap in the author's most active subfields. citations · hero ref

Author Last Decade Papers Cites
Harold E. Van Wart 2.5k 2.4k 1.8k 972 551 105 6.4k
Masato Tanaka 1.3k 0.5× 6.2k 2.6× 1.7k 0.9× 895 0.9× 450 0.8× 203 14.8k
Motowo Nakajima 2.2k 0.9× 5.9k 2.4× 2.7k 1.5× 649 0.7× 283 0.5× 225 10.3k
Tor Ny 2.7k 1.1× 2.1k 0.9× 440 0.2× 2.0k 2.1× 139 0.3× 140 6.8k
Philip J. Hogg 1.1k 0.4× 4.0k 1.7× 613 0.3× 2.0k 2.0× 474 0.9× 186 8.4k
Kenneth A. Thomas 1.5k 0.6× 5.7k 2.4× 1.3k 0.7× 274 0.3× 251 0.5× 92 8.5k
John Hood 938 0.4× 4.2k 1.7× 1.1k 0.6× 781 0.8× 503 0.9× 56 7.2k
Vicki Plaks 2.4k 1.0× 3.5k 1.5× 3.3k 1.8× 263 0.3× 124 0.2× 52 8.1k
Hans Brandstetter 712 0.3× 2.5k 1.0× 1.3k 0.7× 1.0k 1.1× 123 0.2× 133 5.1k
Pan Zheng 1.8k 0.7× 6.8k 2.8× 3.4k 1.8× 706 0.7× 360 0.7× 265 15.8k
Bonnie F. Sloane 6.4k 2.6× 6.8k 2.8× 4.3k 2.3× 948 1.0× 954 1.7× 211 14.5k

Countries citing papers authored by Harold E. Van Wart

Since Specialization
Citations

This map shows the geographic impact of Harold E. Van Wart's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Harold E. Van Wart with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Harold E. Van Wart more than expected).

Fields of papers citing papers by Harold E. Van Wart

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Harold E. Van Wart. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Harold E. Van Wart. The network helps show where Harold E. Van Wart may publish in the future.

Co-authorship network of co-authors of Harold E. Van Wart

This figure shows the co-authorship network connecting the top 25 collaborators of Harold E. Van Wart. A scholar is included among the top collaborators of Harold E. Van Wart based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Harold E. Van Wart. Harold E. Van Wart is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Williams, Ashley Robinson, Robert W. Sullivan, Erin K. Bradley, et al.. (2003). Novel Inhibitors of Procollagen C-Terminal Proteinase. Part 1: Diamino Acid Hydroxamates. Bioorganic & Medicinal Chemistry Letters. 13(13). 2101–2104. 14 indexed citations
2.
Williams, Ashley Robinson, Erin K. Bradley, Jeffrey A. Campbell, et al.. (2003). Novel inhibitors of procollagen C-Proteinase. Part 2: glutamic acid hydroxamates. Bioorganic & Medicinal Chemistry Letters. 13(14). 2381–2384. 15 indexed citations
3.
Broka, Chris A., Robert L. Martin, Christine Chan, et al.. (2002). Amino acid derived sulfonamide hydroxamates as inhibitors of procollagen C-Proteinase. Part 2: Solid-Phase optimization of side chains. Bioorganic & Medicinal Chemistry Letters. 12(8). 1233–1235. 12 indexed citations
4.
5.
Billedeau, Roland, et al.. (2000). Solid-phase synthesis of di- and tripeptidic hydroxamic acids as inhibitors of procollagen C-proteinase. Bioorganic & Medicinal Chemistry Letters. 10(22). 2513–2516. 17 indexed citations
6.
Martin, Robert L., et al.. (1997). Hydrolysis of a Broad Spectrum of Extracellular Matrix Proteins by Human Macrophage Elastase. Journal of Biological Chemistry. 272(18). 12189–12194. 261 indexed citations
7.
Dioszegi, Marianna, Paul J. Cannon, & Harold E. Van Wart. (1995). [25] Vertebrate collagenases. Methods in enzymology on CD-ROM/Methods in enzymology. 248. 413–431. 34 indexed citations
8.
9.
Netzel–Arnett, Sarah, et al.. (1994). Evidence for a Triple Helix Recognition Site in the Hemopexin‐like Domains of Human Fibroblast and Neutrophil Interstitial Collagenasesa. Annals of the New York Academy of Sciences. 732(1). 22–30. 14 indexed citations
10.
Wart, Harold E. Van, et al.. (1994). Differential Effect of Halide Anions on the Hydrolysis of Different Dansyl Substrates by Thermolysin. Biochemistry. 33(21). 6516–6523. 10 indexed citations
11.
Mallya, Satish, Kasim A. Mookhtiar, & Harold E. Van Wart. (1992). Kinetics of hydrolysis of type I, II, and III collagens by the class I and IIClostridium histolyticum collagenases. Journal of Protein Chemistry. 11(1). 99–107. 46 indexed citations
12.
Netzel–Arnett, Sarah, Satish Mallya, Hideaki Nagase, Henning Birkedal‐Hansen, & Harold E. Van Wart. (1991). Continuously recording fluorescent assays optimized for five human matrix metalloproteinases. Analytical Biochemistry. 195(1). 86–92. 100 indexed citations
13.
Baek, Haesun Kang, et al.. (1990). Construction of a fast, inexpensive rapid-scanning diode-array detector and spectrometer. Analytical Biochemistry. 190(1). 134–140. 3 indexed citations
14.
Mookhtiar, Kasim A. & Harold E. Van Wart. (1990). Purification to homogeneity of latent and active 58-kilodalton forms of human neutrophil collagenase. Biochemistry. 29(47). 10620–10627. 37 indexed citations
15.
Mallya, Satish, Kasim A. Mookhtiar, Yi Gao, et al.. (1990). Characterization of 58-kilodalton human neutrophil collagenase: comparison with human fibroblast collagenase. Biochemistry. 29(47). 10628–10634. 79 indexed citations
16.
Chuang, Woei‐Jer, Steve A. Johnson, & Harold E. Van Wart. (1988). Resonance Raman spectra of bovine liver catalase: Enhancement of proximal tyrosinate vibrations. Journal of Inorganic Biochemistry. 34(3). 201–219. 21 indexed citations
17.
Mookhtiar, Kasim A., Damian Grobelny, Richard E. Galardy, & Harold E. Van Wart. (1988). Ketone-substrate analogues of Clostridium histolyticum collagenases: tight-binding transition-state analogue inhibitors. Biochemistry. 27(12). 4299–4304. 11 indexed citations
18.
Angleton, Eddie L. & Harold E. Van Wart. (1988). Preparation by direct metal exchange and kinetic study of active site metal substituted class I and class II Clostridium histolyticum collagenases. Biochemistry. 27(19). 7413–7418. 18 indexed citations
19.
Angleton, Eddie L. & Harold E. Van Wart. (1988). Preparation and reconstitution with divalent metal ions of class I and class II Clostridium histolyticum apocollagenases. Biochemistry. 27(19). 7406–7412. 22 indexed citations
20.
Wart, Harold E. Van & Bert L. Vallée. (1977). Exchange inert Co(III)-carboxypeptidase A: A catalytically inactive metallocarboxypeptidase. Biochemical and Biophysical Research Communications. 75(3). 732–738. 8 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact

Breakdown of academic impact, for papers by Masato Tanaka Breakdown of academic impact, for papers by Motowo Nakajima Breakdown of academic impact, for papers by Tor Ny Breakdown of academic impact, for papers by Philip J. Hogg Breakdown of academic impact, for papers by Kenneth A. Thomas Breakdown of academic impact, for papers by John Hood Breakdown of academic impact, for papers by Vicki Plaks Breakdown of academic impact, for papers by Hans Brandstetter Breakdown of academic impact, for papers by Pan Zheng Breakdown of academic impact, for papers by Bonnie F. Sloane
Rankless by CCL
2026