H. Michael Petrassi

3.8k total citations · 1 hit paper
29 papers, 2.4k citations indexed

About

H. Michael Petrassi is a scholar working on Molecular Biology, Physiology and Oncology. According to data from OpenAlex, H. Michael Petrassi has authored 29 papers receiving a total of 2.4k indexed citations (citations by other indexed papers that have themselves been cited), including 24 papers in Molecular Biology, 7 papers in Physiology and 6 papers in Oncology. Recurrent topics in H. Michael Petrassi's work include Amyloidosis: Diagnosis, Treatment, Outcomes (11 papers), Alzheimer's disease research and treatments (6 papers) and Protein Kinase Regulation and GTPase Signaling (5 papers). H. Michael Petrassi is often cited by papers focused on Amyloidosis: Diagnosis, Treatment, Outcomes (11 papers), Alzheimer's disease research and treatments (6 papers) and Protein Kinase Regulation and GTPase Signaling (5 papers). H. Michael Petrassi collaborates with scholars based in United States and United Kingdom. H. Michael Petrassi's co-authors include Jeffery W. Kelly, James C. Sacchettini, Thomas Klabunde, Vibha Oza, Jason Matzen, Prakash Raman, Edward K. Koepf, Marius Sudol, Hans E. Purkey and K. Barry Sharpless and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of the American Chemical Society and Blood.

In The Last Decade

H. Michael Petrassi

27 papers receiving 2.4k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Chemical activation of the mechanotransduction channel Piezo1

2015 487 citations Jason Matzen, David C. Tully et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
H. Michael Petrassi United States	18	1.6k	831	374	304	263	29	2.4k
Richard Foster United Kingdom	29	1.2k 0.8×	674 0.8×	169 0.5×	164 0.5×	156 0.6×	97	2.4k
Choel Kim United States	27	2.0k 1.3×	316 0.4×	235 0.6×	177 0.6×	200 0.8×	56	2.6k
Francesca Magherini Italy	26	1.3k 0.8×	273 0.3×	240 0.6×	259 0.9×	367 1.4×	80	2.2k
Alan C. Rigby United States	25	1.6k 1.0×	525 0.6×	169 0.5×	132 0.4×	182 0.7×	58	2.7k
Samarjit Patnaik United States	22	1.0k 0.6×	650 0.8×	497 1.3×	546 1.8×	96 0.4×	61	3.1k
Yuhong Du United States	34	1.9k 1.2×	227 0.3×	239 0.6×	287 0.9×	427 1.6×	96	3.0k
Mark R. Wardell United States	24	1.7k 1.0×	552 0.7×	463 1.2×	62 0.2×	360 1.4×	36	3.3k
Robert T. Nolte United States	27	4.3k 2.6×	567 0.7×	243 0.6×	623 2.0×	534 2.0×	33	5.8k
Yoshikazu Iwasawa Japan	23	1.3k 0.8×	281 0.3×	203 0.5×	433 1.4×	395 1.5×	68	2.0k
Daniel F. Wyss United States	31	1.6k 1.0×	284 0.3×	132 0.4×	382 1.3×	323 1.2×	58	3.4k

Countries citing papers authored by H. Michael Petrassi

Since Specialization

Citations

This map shows the geographic impact of H. Michael Petrassi's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by H. Michael Petrassi with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites H. Michael Petrassi more than expected).

Fields of papers citing papers by H. Michael Petrassi

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by H. Michael Petrassi. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by H. Michael Petrassi. The network helps show where H. Michael Petrassi may publish in the future.

Co-authorship network of co-authors of H. Michael Petrassi

This figure shows the co-authorship network connecting the top 25 collaborators of H. Michael Petrassi. A scholar is included among the top collaborators of H. Michael Petrassi based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with H. Michael Petrassi. H. Michael Petrassi is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Sanchez, Julian, Wen Ren, Carlton E. Ash, et al.. (2024). Discovery of Potent and Selective Pyridone-Based Small Molecule Kinetic Stabilizers of Amyloidogenic Immunoglobulin Light Chains. Journal of Medicinal Chemistry. 67(23). 21070–21105.

Qin, Bo, Yaocheng Li, Jianying Wang, et al.. (2024). Small Molecule Kinetic Stabilizers Reduce Amyloidogenicity of Free Light Chain Proteins of Diverse Sequences in λ Light Chain Amyloidosis. Blood. 144(Supplement 1). 3372–3372.

Yang, Baiyuan, Gencheng Li, Grant A. L. Bare, et al.. (2023). Synthesis and structure–activity relationships of aryl fluorosulfate-based inhibitors as novel antitubercular agents. Bioorganic & Medicinal Chemistry Letters. 98. 129596–129596. 3 indexed citations

Morgan, Gareth J., et al.. (2023). Pharmacological stabilization of the native state of full-length immunoglobulin light chains to treat light chain amyloidosis. Current Opinion in Chemical Biology. 75. 102319–102319. 7 indexed citations

Pisu, Davide, Kaley M. Wilburn, H. Michael Petrassi, et al.. (2022). Iron limitation in M. tuberculosis has broad impact on central carbon metabolism. Communications Biology. 5(1). 685–685. 17 indexed citations

Wilburn, Kaley M., Christine R. Montague, Ashley K. Woods, et al.. (2022). Pharmacological and genetic activation of cAMP synthesis disrupts cholesterol utilization in Mycobacterium tuberculosis. PLoS Pathogens. 18(2). e1009862–e1009862. 16 indexed citations

Janes, Jeff, Emily Chen, Nicole H. Rogers, et al.. (2018). The ReFRAME library as a comprehensive drug repurposing library and its application to the treatment of cryptosporidiosis. Proceedings of the National Academy of Sciences. 115(42). 10750–10755. 125 indexed citations

Choi, Seung Hyuk, Sang Jun Lee, Mitchell Hull, et al.. (2017). Targeted Disruption of Myc–Max Oncoprotein Complex by a Small Molecule. ACS Chemical Biology. 12(11). 2715–2719. 52 indexed citations

Brand, Martin D., Renata L.S. Goncalves, Adam L. Orr, et al.. (2016). Suppressors of Superoxide-H 2 O 2 Production at Site I Q of Mitochondrial Complex I Protect against Stem Cell Hyperplasia and Ischemia-Reperfusion Injury. Cell Metabolism. 24(4). 582–592. 170 indexed citations

10.

Orr, Adam L., Leonardo Vargas, Jason Matzen, et al.. (2015). Suppressors of superoxide production from mitochondrial complex III. Nature Chemical Biology. 11(11). 834–836. 159 indexed citations

11.

Liu, Bin, Younghee Lee, H. Michael Petrassi, et al.. (2010). Discovery and SAR of a series of 4,6-diamino-1,3,5-triazin-2-ol as novel non-nucleoside reverse transcriptase inhibitors of HIV-1. Bioorganic & Medicinal Chemistry Letters. 20(22). 6592–6596. 17 indexed citations

12.

Li, Jun, et al.. (2008). Substrate optimization for monitoring cathepsin C activity in live cells. Bioorganic & Medicinal Chemistry. 17(3). 1064–1070. 14 indexed citations

13.

Tully, David C., Arnab K. Chatterjee, Jennifer Williams, et al.. (2008). Discovery of inhibitors of the channel-activating protease prostasin (CAP1/PRSS8) utilizing structure-based design. Bioorganic & Medicinal Chemistry Letters. 18(22). 5895–5899. 15 indexed citations

14.

Petrassi, H. Michael, Jennifer Williams, Jun Li, et al.. (2005). A strategy to profile prime and non-prime proteolytic substrate specificity. Bioorganic & Medicinal Chemistry Letters. 15(12). 3162–3166. 39 indexed citations

15.

McCammon, Margaret G., David J. Scott, Catherine A. Keetch, et al.. (2002). Screening Transthyretin Amyloid Fibril Inhibitors. Structure. 10(6). 851–863. 89 indexed citations

16.

Sacchettini, James C., Thomas Klabunde, H. Michael Petrassi, et al.. (2000). Rational design of potent human transthyretin amyloid disease inhibitors.. Nature Structural Biology. 7(4). 312–321. 311 indexed citations

17.

Koepf, Edward K., H. Michael Petrassi, Marius Sudol, & Jeffery W. Kelly. (1999). WW: An isolated three‐stranded antiparallel β‐sheet domain that unfolds and refolds reversibly; evidence for a structured hydrophobic cluster in urea and GdnHCl and a disordered thermal unfolded state. Protein Science. 8(4). 841–853. 138 indexed citations

18.

Oza, Vibha, H. Michael Petrassi, Hans E. Purkey, & Jeffery W. Kelly. (1999). Synthesis and evaluation of anthranilic acid-based transthyretin amyloid fibril inhibitors. Bioorganic & Medicinal Chemistry Letters. 9(1). 1–6. 65 indexed citations

19.

Koepf, Edward K., H. Michael Petrassi, Gayathri Ratnaswamy, et al.. (1999). Characterization of the Structure and Function of W → F WW Domain Variants: Identification of a Natively Unfolded Protein That Folds upon Ligand Binding. Biochemistry. 38(43). 14338–14351. 74 indexed citations

20.

Gestwicki, Jason E., et al.. (1996). Effect of Microwave Radiation on Copper(II) 2,2‘-Bipyridyl-Mediated Hydrolysis of Bis(p-nitrophenyl) Phosphodiester and Enzymatic Hydrolysis of Carbohydrates. The Journal of Organic Chemistry. 61(26). 9599–9602. 8 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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