Frank Guarnieri

4.9k total citations · 1 hit paper
53 papers, 4.1k citations indexed

About

Frank Guarnieri is a scholar working on Molecular Biology, Cellular and Molecular Neuroscience and Atomic and Molecular Physics, and Optics. According to data from OpenAlex, Frank Guarnieri has authored 53 papers receiving a total of 4.1k indexed citations (citations by other indexed papers that have themselves been cited), including 35 papers in Molecular Biology, 12 papers in Cellular and Molecular Neuroscience and 7 papers in Atomic and Molecular Physics, and Optics. Recurrent topics in Frank Guarnieri's work include Protein Structure and Dynamics (20 papers), Receptor Mechanisms and Signaling (12 papers) and Neuroscience and Neuropharmacology Research (6 papers). Frank Guarnieri is often cited by papers focused on Protein Structure and Dynamics (20 papers), Receptor Mechanisms and Signaling (12 papers) and Neuroscience and Neuropharmacology Research (6 papers). Frank Guarnieri collaborates with scholars based in United States, Denmark and South Africa. Frank Guarnieri's co-authors include J. Thomas August, Kevin F. Staveley-O’Carroll, T.‐C. Wu, Drew M. Pardoll, Hyam I. Levitsky, Juan Antonio Ballesteros‐Cánovas, Ernest L. Mehler, W. Clark Still, Harel Weinstein and Rui Xu and has published in prestigious journals such as Science, Proceedings of the National Academy of Sciences and Journal of the American Chemical Society.

In The Last Decade

Frank Guarnieri

53 papers receiving 3.9k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Treatment of established tumors with a novel vaccine that enhances major histocompatibility class II presentation of tumor antigen.

1996 870 citations Frank Guarnieri, Kevin F. Staveley-O’Carroll et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Frank Guarnieri United States	31	2.5k	1.3k	842	464	458	53	4.1k
Ronald W. Barrett United States	28	3.6k 1.4×	483 0.4×	376 0.4×	354 0.8×	457 1.0×	59	5.4k
Eric W. Hewitt United Kingdom	35	2.9k 1.1×	1.1k 0.8×	241 0.3×	655 1.4×	484 1.1×	56	5.1k
Friedrich W. Herberg Germany	41	4.0k 1.6×	313 0.2×	508 0.6×	311 0.7×	215 0.5×	153	5.1k
Brian A. Fox United States	18	4.9k 1.9×	914 0.7×	2.9k 3.5×	630 1.4×	134 0.3×	45	6.4k
Kurt S. Thorn United States	26	4.1k 1.6×	322 0.2×	378 0.4×	304 0.7×	372 0.8×	35	5.8k
Dean R. Madden United States	30	2.8k 1.1×	2.2k 1.7×	870 1.0×	269 0.6×	280 0.6×	92	5.3k
Bernard Maigret France	38	2.6k 1.0×	263 0.2×	1.1k 1.3×	505 1.1×	216 0.5×	157	4.9k
M.G. Rudolph Switzerland	34	2.3k 0.9×	1.6k 1.2×	131 0.2×	607 1.3×	309 0.7×	89	4.5k
Jacqueline Cherfils France	39	5.0k 2.0×	444 0.3×	283 0.3×	533 1.1×	259 0.6×	108	6.4k
Sjoerd J. de Vries Netherlands	21	3.9k 1.5×	502 0.4×	196 0.2×	416 0.9×	259 0.6×	37	5.0k

Countries citing papers authored by Frank Guarnieri

Since Specialization

Citations

This map shows the geographic impact of Frank Guarnieri's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Frank Guarnieri with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Frank Guarnieri more than expected).

Fields of papers citing papers by Frank Guarnieri

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Frank Guarnieri. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Frank Guarnieri. The network helps show where Frank Guarnieri may publish in the future.

Co-authorship network of co-authors of Frank Guarnieri

This figure shows the co-authorship network connecting the top 25 collaborators of Frank Guarnieri. A scholar is included among the top collaborators of Frank Guarnieri based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Frank Guarnieri. Frank Guarnieri is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Xu, Yu, et al.. (2022). Use of a Molecular Switch Probe to Activate or Inhibit GIRK1 Heteromers In Silico Reveals a Novel Gating Mechanism. International Journal of Molecular Sciences. 23(18). 10820–10820. 3 indexed citations

Guarnieri, Frank, et al.. (2019). Fragment-based design of small molecule PCSK9 inhibitors using simulated annealing of chemical potential simulations. PLoS ONE. 14(12). e0225780–e0225780. 12 indexed citations

Kulp, John L., et al.. (2017). Hot-spot identification on a broad class of proteins and RNA suggest unifying principles of molecular recognition. PLoS ONE. 12(8). e0183327–e0183327. 5 indexed citations

Dickson, John K., Thomas E. Barta, Brian Grella, et al.. (2017). Design, synthesis and biological evaluation of renin inhibitors guided by simulated annealing of chemical potential simulations. Bioorganic & Medicinal Chemistry. 25(15). 3947–3963. 4 indexed citations

Guarnieri, Frank. (2015). Designing an Orally Available Nontoxic p38 Inhibitor with a Fragment-Based Strategy. Methods in molecular biology. 1289. 211–226. 7 indexed citations

Guarnieri, Frank. (2015). Designing a Small Molecule Erythropoietin Mimetic. Methods in molecular biology. 1289. 185–210. 7 indexed citations

Kulp, John L., et al.. (2012). A fragment-based approach to the SAMPL3 Challenge. Journal of Computer-Aided Molecular Design. 26(5). 583–594. 17 indexed citations

Bradbury, M. W. B., Decherd Stump, Frank Guarnieri, & Paul D. Berk. (2011). Molecular Modeling and Functional Confirmation of a Predicted Fatty Acid Binding Site of Mitochondrial Aspartate Aminotransferase. Journal of Molecular Biology. 412(3). 412–422. 22 indexed citations

Guarnieri, Frank, J. L. Spencer, Edgar C. Lucey, Matthew A. Nugent, & Phillip J. Stone. (2010). A human surfactant peptide-elastase inhibitor construct as a treatment for emphysema. Proceedings of the National Academy of Sciences. 107(23). 10661–10666. 16 indexed citations

10.

Chuang, Gwo‐Yu, Dima Kozakov, Ryan Brenke, et al.. (2009). Binding Hot Spots and Amantadine Orientation in the Influenza A Virus M2 Proton Channel. Biophysical Journal. 97(10). 2846–2853. 35 indexed citations

11.

Whitnell, Robert M., Dow P. Hurst, Patricia H. Reggio, & Frank Guarnieri. (2007). Conformational memories with variable bond angles. Journal of Computational Chemistry. 29(5). 741–752. 12 indexed citations

12.

Shi, Lei, George Liapakis, Rui Xu, et al.. (2002). β2 Adrenergic Receptor Activation. Journal of Biological Chemistry. 277(43). 40989–40996. 354 indexed citations

13.

McAllister, Sean D., Tao Qing, Judy Barnett‐Norris, et al.. (2002). A critical role for a tyrosine residue in the cannabinoid receptors for ligand recognition. Biochemical Pharmacology. 63(12). 2121–2136. 55 indexed citations

14.

Jensen, Anne D., Frank Guarnieri, Søren G. F. Rasmussen, et al.. (2001). Agonist-induced Conformational Changes at the Cytoplasmic Side of Transmembrane Segment 6 in the β2 Adrenergic Receptor Mapped by Site-selective Fluorescent Labeling. Journal of Biological Chemistry. 276(12). 9279–9290. 121 indexed citations

15.

Mehler, Ernest L. & Frank Guarnieri. (1999). A Self-Consistent, Microenvironment Modulated Screened Coulomb Potential Approximation to Calculate pH-Dependent Electrostatic Effects in Proteins. Biophysical Journal. 77(1). 3–22. 141 indexed citations

16.

Mezei, Mihaly & Frank Guarnieri. (1998). Computer Simulation Studies of the Fully Solvated Wild-type and Mutated GnRH in Extended and βturn Conformations. Journal of Biomolecular Structure and Dynamics. 16(3). 723–732. 14 indexed citations

17.

Ruff, Albert L., Frank Guarnieri, Kevin F. Staveley-O’Carroll, Robert F. Siliciano, & Thomas J. August. (1997). The Enhanced Immune Response to the HIV gp160/LAMP Chimeric Gene Product Targeted to the Lysosome Membrane Protein Trafficking Pathway. Journal of Biological Chemistry. 272(13). 8671–8678. 58 indexed citations

18.

Laakkonen, Liisa, et al.. (1996). Restricted analogues provide evidence of a biologically active conformation of thyrotropin-releasing hormone.. Molecular Pharmacology. 49(6). 1092–1096. 13 indexed citations

19.

Levitsky, Hyam I., Joel M. Montgomery, Mojgan Ahmadzadeh, et al.. (1996). Immunization with granulocyte-macrophage colony-stimulating factor-transduced, but not B7-1-transduced, lymphoma cells primes idiotype-specific T cells and generates potent systemic antitumor immunity. The Journal of Immunology. 156(10). 3858–3865. 155 indexed citations

20.

Guarnieri, Frank & Stephen R. Wilson. (1995). Conformational memories and a simulated annealing program that learns: Application to LTB₄. Journal of Computational Chemistry. 16(5). 648–653. 30 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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