Edward C. O’Rourke

2.6k total citations · 1 hit paper
15 papers, 2.2k citations indexed

About

Edward C. O’Rourke is a scholar working on Molecular Biology, Oncology and Genetics. According to data from OpenAlex, Edward C. O’Rourke has authored 15 papers receiving a total of 2.2k indexed citations (citations by other indexed papers that have themselves been cited), including 11 papers in Molecular Biology, 4 papers in Oncology and 3 papers in Genetics. Recurrent topics in Edward C. O’Rourke's work include Protein Kinase Regulation and GTPase Signaling (4 papers), Virus-based gene therapy research (3 papers) and Viral Infectious Diseases and Gene Expression in Insects (3 papers). Edward C. O’Rourke is often cited by papers focused on Protein Kinase Regulation and GTPase Signaling (4 papers), Virus-based gene therapy research (3 papers) and Viral Infectious Diseases and Gene Expression in Insects (3 papers). Edward C. O’Rourke collaborates with scholars based in United States, Malaysia and Sweden. Edward C. O’Rourke's co-authors include Venkata Nanduri, Mariano Barbacid, Rüdiger Klein, Peter Tapley, Shuqian Jing, Kevin R. Jones, Louis F. Reichardt, Carlos Cordon‐Cardo, Karla Kovary and Fabienne Lamballe and has published in prestigious journals such as Cell, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

In The Last Decade

Edward C. O’Rourke

15 papers receiving 2.1k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The trk proto-oncogene encodes a receptor for nerve growth factor

1991 1.2k citations Rüdiger Klein, Venkata Nanduri et al. Cell profile →

Peers

Edward C. O’Rourke

CMN

ONCOL

Arne Sutter Germany

Linda K. Long United States

Enrique Escandón United States

L. Julie Huber United States

Christine D. Pozniak United States

D Wen United States

Clive Da Costa United Kingdom

Craig Crowley United States

Stuart J. Rabin United States

Wilfredo Mellado United States

Arne Sutter Germany

Edward C. O’Rourke

1.3k ×1.0

957 ×0.8

CMN

330 ×0.9

204 ×0.7

ONCOL

173 ×0.8

Citations per year, relative to Edward C. O’Rourke Edward C. O’Rourke (= 1×) peers Arne Sutter

Countries citing papers authored by Edward C. O’Rourke

Since Specialization

Citations

This map shows the geographic impact of Edward C. O’Rourke's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Edward C. O’Rourke with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Edward C. O’Rourke more than expected).

Fields of papers citing papers by Edward C. O’Rourke

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Edward C. O’Rourke. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Edward C. O’Rourke. The network helps show where Edward C. O’Rourke may publish in the future.

Co-authorship network of co-authors of Edward C. O’Rourke

This figure shows the co-authorship network connecting the top 25 collaborators of Edward C. O’Rourke. A scholar is included among the top collaborators of Edward C. O’Rourke based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Edward C. O’Rourke. Edward C. O’Rourke is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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15 of 15 papers shown

O’Rourke, Edward C., Bernadette Kienzle, Laura Blinderman, et al.. (1995). A 30-Amino Acid Truncation of the Microsomal Triglyceride Transfer Protein Large Subunit Disrupts Its Interaction with Protein Disulfide-isomerase and Causes Abetalipoproteinemia. Journal of Biological Chemistry. 270(24). 14281–14285. 63 indexed citations

Metz, R, Andrew J. Bannister, Christian Hagemeier, et al.. (1994). c-Fos-Induced Activation of a TATA-Box-Containing Promoter Involves Direct Contact with TATA-Box-Binding Protein. Molecular and Cellular Biology. 14(9). 6021–6029. 24 indexed citations

Heinrich, Julia, et al.. (1994). Biological Activity of the Growth Factor-Induced Cytokine N51: Structure-Function Analysis Using N51/Interleukin-8 Chimeric Molecules. Molecular and Cellular Biology. 14(5). 2849–2861. 15 indexed citations

Metz, R, Andrew J. Bannister, Christian Hagemeier, et al.. (1994). c-Fos-induced activation of a TATA-box-containing promoter involves direct contact with TATA-box-binding protein.. Molecular and Cellular Biology. 14(9). 6021–6029. 63 indexed citations

Spana, Carl, Edward C. O’Rourke, Joseph B. Bolen, & Joseph Fargnoli. (1993). Analysis of the Tyrosine Protein Kinase p56lck Expressed as a Glutathione S-Transferase Fusion Protein in Spodoptera frugiperda Cells. Protein Expression and Purification. 4(5). 390–397. 16 indexed citations

Goodman, Laurie, et al.. (1993). Purified yeast protein farnesyltransferase is structurally and functionally similar to its mammalian counterpart. Biochemical Journal. 289(1). 25–31. 48 indexed citations

Cordon‐Cardo, Carlos, Peter Tapley, Shuqian Jing, et al.. (1991). The trk tyrosine protein kinase mediates the mitogenic properties of nerve growth factor and neurotrophin-3. Cell. 66(1). 173–183. 462 indexed citations

Klein, Rüdiger, et al.. (1991). The trk proto-oncogene encodes a receptor for nerve growth factor. Cell. 65(1). 189–197. 1209 indexed citations breakdown →

Manne, Veeraswamy, Daniel M. Roberts, Alyson K. Tobin, et al.. (1990). Identification and preliminary characterization of protein-cysteine farnesyltransferase.. Proceedings of the National Academy of Sciences. 87(19). 7541–7545. 125 indexed citations

10.

Quilliam, Lawrence A., Channing J. Der, Robin Clark, et al.. (1990). Biochemical Characterization of Baculovirus-Expressed rap1A/ Krev-1 and Its Regulation by GTPase-Activating Proteins. Molecular and Cellular Biology. 10(6). 2901–2908. 10 indexed citations

11.

Quilliam, Lawrence A., Channing J. Der, R Clark, et al.. (1990). Biochemical characterization of baculovirus-expressed rap1A/Krev-1 and its regulation by GTPase-activating proteins.. Molecular and Cellular Biology. 10(6). 2901–2908. 53 indexed citations

12.

Devlin, James J., Patricia E. Devlin, Robin Clark, et al.. (1989). Novel Expression of Chimeric Plasminogen Activators in Insect Cells. Nature Biotechnology. 7(3). 286–292. 14 indexed citations

13.

Clark, R, Martha R. Stampfer, Robert Milley, et al.. (1988). Transformation of human mammary epithelial cells by oncogenic retroviruses.. PubMed. 48(16). 4689–94. 82 indexed citations

14.

O’Rourke, Edward C., Robert J. Drummond, & Abla A. Creasey. (1984). Binding of ¹²⁵I-Labeled Recombinant β Interferon (IFN-β Ser₁₇) to Human Cells. Molecular and Cellular Biology. 4(12). 2745–2749. 19 indexed citations

15.

O’Rourke, Edward C., et al.. (1974). A procedure for selective acid extraction, staining and quantitative measurement of histones inAllium root nuclei. The Histochemical Journal. 6(4). 395–407. 2 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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