Edward C. O’Rourke

2.6k citations

15 papers · 2.2k indexed · 1 hit paper · h-index 13

Molecular Biology top 5%
Cellular and Molecular Neuroscience top 1%
Developmental Neuroscience top 1%
Oncology top 10%
Cell Biology top 10%

Co-authors: Venkata Nanduri Mariano Barbacid Rüdiger Klein Peter Tapley Shuqian Jing Kevin R. Jones Louis F. Reichardt Carlos Cordon‐Cardo
Topics: Protein Kinase Regulation and GTPase Signaling (4 papers)Virus-based gene therapy research (3 papers)Viral Infectious Diseases and Gene Expression in Insects (3 papers)
Cited by: Developmental Neuroscience Cellular and Molecular Neuroscience Molecular Biology
Journals: Cell Proceedings of the National Academy of Sciences Journal of Biological Chemistry
Partner nations: United States Malaysia Sweden

In The Last Decade

Edward C. O’Rourke

15 papers receiving 2.1k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The trk proto-oncogene encodes a receptor for nerve growth factor

1991 1.2k citations Rüdiger Klein, Venkata Nanduri et al. Cell profile →

Peers

Countries citing papers authored by Edward C. O’Rourke

Since Specialization

Citations

This map shows the geographic impact of Edward C. O’Rourke's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Edward C. O’Rourke with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Edward C. O’Rourke more than expected).

Fields of papers citing papers by Edward C. O’Rourke

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Edward C. O’Rourke. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Edward C. O’Rourke. The network helps show where Edward C. O’Rourke may publish in the future.

Co-authorship network of co-authors of Edward C. O’Rourke

This figure shows the co-authorship network connecting the top 25 collaborators of Edward C. O’Rourke. A scholar is included among the top collaborators of Edward C. O’Rourke based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Edward C. O’Rourke. Edward C. O’Rourke is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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15 of 15 papers shown

#	Work	Indexed citations
1	A 30-Amino Acid Truncation of the Microsomal Triglyceride Transfer Protein Large Subunit Disrupts Its Interaction with Protein Disulfide-isomerase and Causes Abetalipoproteinemia 1995 ·Journal of Biological Chemistry ·(unknown),(unknown),Edward C. O’Rourke,Bernadette Kienzle,Laura Blinderman,David Gordon,(unknown),Gordon W. Robinson,Richard E. Gregg,Daniel J. Rader,John R. Wetterau	63
2	c-Fos-Induced Activation of a TATA-Box-Containing Promoter Involves Direct Contact with TATA-Box-Binding Protein 1994 ·Molecular and Cellular Biology ·R Metz,Andrew J. Bannister,(unknown),Christian Hagemeier,Edward C. O’Rourke,A Cook,Rodrigo Bravo,Tony Kouzarides	24
3	Biological Activity of the Growth Factor-Induced Cytokine N51: Structure-Function Analysis Using N51/Interleukin-8 Chimeric Molecules 1994 ·Molecular and Cellular Biology ·Julia Heinrich,Edward C. O’Rourke,Lihong Chen,(unknown),Karen S. Dorfman,Rodrigo Bravo	15
4	c-Fos-induced activation of a TATA-box-containing promoter involves direct contact with TATA-box-binding protein. 1994 ·Molecular and Cellular Biology ·R Metz,Andrew J. Bannister,(unknown),Christian Hagemeier,Edward C. O’Rourke,A Cook,Rodrigo Bravo,Tony Kouzarides	63
5	Analysis of the Tyrosine Protein Kinase p56lck Expressed as a Glutathione S-Transferase Fusion Protein in Spodoptera frugiperda Cells 1993 ·Protein Expression and Purification ·Carl Spana,Edward C. O’Rourke,Joseph B. Bolen,Joseph Fargnoli	16
6	Purified yeast protein farnesyltransferase is structurally and functionally similar to its mammalian counterpart 1993 ·Biochemical Journal ·(unknown),Laurie Goodman,Sandeep K. Tripathy,Edward C. O’Rourke,Veeraswamy Manne,Fuyuhiko Tamanoi	48
7	The trk tyrosine protein kinase mediates the mitogenic properties of nerve growth factor and neurotrophin-3 1991 ·Cell ·Carlos Cordon‐Cardo,Peter Tapley,Shuqian Jing,Venkata Nanduri,Edward C. O’Rourke,Fabienne Lamballe,Karla Kovary,Rüdiger Klein,Kevin R. Jones,Louis F. Reichardt,Mariano Barbacid	462
8	The trk proto-oncogene encodes a receptor for nerve growth factorbreakdown → 1991 ·Cell ·Rüdiger Klein,(unknown),Venkata Nanduri,Edward C. O’Rourke,Mariano Barbacid	1209
9	Identification and preliminary characterization of protein-cysteine farnesyltransferase. 1990 ·Proceedings of the National Academy of Sciences ·Veeraswamy Manne,Daniel M. Roberts,Alyson K. Tobin,Edward C. O’Rourke,(unknown),Chester A. Meyers,Naseem Ahmed,Bodo Kurz,Marilyn D. Resh,H F Kung	125
10	Biochemical Characterization of Baculovirus-Expressed rap1A/ Krev-1 and Its Regulation by GTPase-Activating Proteins 1990 ·Molecular and Cellular Biology ·Lawrence A. Quilliam,Channing J. Der,Robin Clark,Edward C. O’Rourke,Ke Zhang,Frank McCormick,Gary Bokoch	10
11	Biochemical characterization of baculovirus-expressed rap1A/Krev-1 and its regulation by GTPase-activating proteins. 1990 ·Molecular and Cellular Biology ·Lawrence A. Quilliam,Channing J. Der,R Clark,Edward C. O’Rourke,(unknown),Frank McCormick,Gary Bokoch	53
12	Novel Expression of Chimeric Plasminogen Activators in Insect Cells 1989 ·Nature Biotechnology ·James J. Devlin,Patricia E. Devlin,Robin Clark,Edward C. O’Rourke,Corey Levenson,Mark David	14
13	Transformation of human mammary epithelial cells by oncogenic retroviruses. 1988 ·PubMed ·R Clark,Martha R. Stampfer,Robert Milley,Edward C. O’Rourke,Kirsten H. Walen,M Kriegler,(unknown),Frank McCormick	82
14	Binding of ¹²⁵I-Labeled Recombinant β Interferon (IFN-β Ser₁₇) to Human Cells 1984 ·Molecular and Cellular Biology ·Edward C. O’Rourke,Robert J. Drummond,Abla A. Creasey	19
15	A procedure for selective acid extraction, staining and quantitative measurement of histones inAllium root nuclei 1974 ·The Histochemical Journal ·Edward C. O’Rourke,(unknown)	2

About Edward C. O’Rourke

Edward C. O’Rourke is a scholar working on Biotechnology, Immunology and Allergy and Molecular Biology, having authored 15 papers that have together received 2.2k indexed citations. Recurring topics across this work include Protein Kinase Regulation and GTPase Signaling (4 papers), Virus-based gene therapy research (3 papers) and Viral Infectious Diseases and Gene Expression in Insects (3 papers). The work is most often cited by research in Developmental Neuroscience (387 citations), Cellular and Molecular Neuroscience (1.2k citations) and Molecular Biology (1.3k citations). Edward C. O’Rourke has collaborated with scholars based in United States, Malaysia and Sweden. Frequent co-authors include Venkata Nanduri, Mariano Barbacid, Rüdiger Klein, Peter Tapley, Shuqian Jing, Kevin R. Jones, Louis F. Reichardt, Carlos Cordon‐Cardo, Karla Kovary and Fabienne Lamballe. Their work appears in journals such as Cell, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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