Edward C. Giardino

643 citations

20 papers · 507 indexed · h-index 13

Hematology top 10%
- Blood Coagulation and Thrombosis Mechanisms 8
- Platelet Disorders and Treatments 2
Genetics top 10%
Organic Chemistry top 10%
- Click Chemistry and Applications 3
- Synthesis of heterocyclic compounds 2
- Synthesis and Reactivity of Sulfur-Containing Compounds 2
Pharmaceutical Science top 10%
Internal Medicine
Molecular Biology
- Chemical Synthesis and Analysis 4
Cardiology and Cardiovascular Medicine
- Atrial Fibrillation Management and Outcomes 3
Surgery
- Heparin-Induced Thrombocytopenia and Thrombosis 2

Co-authors: Bruce E. Maryanoff Bruce P. Damiano Barbara J. Haertlein Patricia Andrade‐Gordon Lawrence de Garavilla Jack A. Kauffman David F. McComsey Annette Eckardt
Cited by: Hematology Genetics Organic Chemistry
Journals: Journal of Medicinal Chemistry (6 papers)Bioorganic & Medicinal Chemistry Letters (3 papers)Journal of Pharmacology and Experimental Therapeutics (2 papers)
Partner nations: United States

In The Last Decade

Edward C. Giardino

20 papers receiving 495 citations

Peers

Countries citing papers authored by Edward C. Giardino

Since Specialization

Citations

This map shows the geographic impact of Edward C. Giardino's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Edward C. Giardino with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Edward C. Giardino more than expected).

Fields of papers citing papers by Edward C. Giardino

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Edward C. Giardino. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Edward C. Giardino. The network helps show where Edward C. Giardino may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Edward C. Giardino, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Edward C. Giardino Line = papers co-authored together Edward C. Giardino links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Cooperative antithrombotic effect from the simultaneous inhibition of thrombin and factor Xa Blood Coagulation & Fibrinolysis ·Edward C. Giardino,Barbara J. Haertlein,Lawrence de Garavilla,Michael J. Costanzo,Bruce P. Damiano,Patricia Andrade‐Gordon,Bruce E. Maryanoff	2010	10
2	Torcetrapib Produces Endothelial Dysfunction Independent of Cholesteryl Ester Transfer Protein Inhibition Journal of Cardiovascular Pharmacology ·Margery A. Connelly,Tom J. Parry,Edward C. Giardino,Zhihong Huang,Wai-man Cheung,Cailin Chen,Frank Cools,Casper Bach-Poulsen,David J. Gallacher,Gee‐Hong Kuo,Troy C. Sarich,Keith T. Demarest,Bruce P. Damiano	2010	30
3	High-content assays for evaluating cellular and hepatic diacylglycerol acyltransferase activity Journal of Lipid Research ·Jenson Qi,Wensheng Lang,Edward C. Giardino,Gary W. Caldwell,Charles E. Smith,Lisa Minor,Andrew L. Darrow,G. Willemsens,Shweta Khande,Peter Roevens,Joannes T. M. Linders,Yin Liang,Margery A. Connelly	2010	21
4	Discovery and Clinical Evaluation of 1-{N-[2-(Amidinoaminooxy)ethyl]amino}carbonylmethyl-6-methyl-3-[2,2-difluoro-2-phenylethylamino]pyrazinone (RWJ-671818), a Thrombin Inhibitor with an Oxyguanidine P1 Motif Journal of Medicinal Chemistry ·Tianbao Lu,Reddy JYC,Shelley K. Ballentine,Edward C. Giardino,John Spurlino,Kathryn Brown,Bruce E. Maryanoff,Bruce E. Tomczuk,Bruce P. Damiano,Umesh Shukla,David W. End,Marcus Mockler,Roger Bone,Mark R. Player	2010	27
5	Orally efficacious thrombin inhibitors with cyanofluorophenylacetamide as the P2 motif Bioorganic & Medicinal Chemistry Letters ·K. D. Kreutter,Tianbao Lu,Lily Lee,Edward C. Giardino,Sharmila Patel,Hui Huang,Guozhang Xu,Mark Fitzgerald,Barbara J. Haertlein,V. Mohan,Carl Crysler,Stephen Eisennagel,Malini Dasgupta,Martin McMillan,John Spurlino,Norman Huebert,Bruce E. Maryanoff,Bruce E. Tomczuk,Bruce P. Damiano,Mark R. Player	2008	24
6	In-Depth Study of Tripeptide-Based α-Ketoheterocycles as Inhibitors of Thrombin. Effective Utilization of the S₁‘ Subsite and Its Implications to Structure-Based Drug Design. Journal of Medicinal Chemistry ·Michael J. Costanzo,Harold R. Almond,Leonard R. Hecker,Eduardo Baudilio Baque Moran,Stephen C. Yabut,Han‐Cheng Zhang,Patricia Andrade‐Gordon,Anja Achtziger,Edward C. Giardino,Jack A. Kauffman,R Ham,Lawrence de Garavilla,Barbara J. Haertlein,Bruce E. Maryanoff	2007	1
7	7-Fluoroindazoles as Potent and Selective Inhibitors of Factor Xa Journal of Medicinal Chemistry ·Max Tamlander,Daniel J. Parks,Tianbao Lu,Panchi Guanoluisa,Reddy JYC,Wenxi Pan,David F. McComsey,Karen L. Milkiewicz,Carl Crysler,宏美小粥,M.C. Abad,Edward C. Giardino,Bruce E. Maryanoff,Bruce P. Damiano,Mark R. Player	2007	45
8	Exploration of Potential Prodrugs of RWJ‐445167, an Oxyguanidine‐based Dual Inhibitor of Thrombin and Factor Xa Chemical Biology & Drug Design ·Bruce E. Maryanoff,David F. McComsey,Michael J. Costanzo,Stephen C. Yabut,Tianbao Lu,Mark R. Player,Edward C. Giardino,Bruce P. Damiano	2006	19
9	A Novel, Potent Dual Inhibitor of the Leukocyte Proteases Cathepsin G and Chymase Journal of Biological Chemistry ·Lawrence de Garavilla,Michael N. Greco,N. Sukumar,Zhiwei Chen,Agustin O. Pineda,F. Scott Mathews,Enrico Di,Edward C. Giardino,Grace I. Wells,Barbara J. Haertlein,Jack A. Kauffman,Anja Achtziger,Claudia K. Derian,Annette Eckardt,Bruce P. Damiano,Patricia Andrade‐Gordon,Bruce E. Maryanoff	2005	75
10	Oxyguanidines. Part 2: Discovery of a novel orally active thrombin inhibitor through structure-based drug design and parallel synthesis Bioorganic & Medicinal Chemistry Letters ·Tianbao Lu,Reddy JYC,Frank T. Coppo,Bruce E. Tomczuk,Carl Crysler,Stephen Eisennagel,John Spurlino,Nusret Ramazanoğlu,Richard Söll,Edward C. Giardino,Roger Bone	2004	19
11	In-Depth Study of Tripeptide-Based α-Ketoheterocycles as Inhibitors of Thrombin. Effective Utilization of the S₁‘ Subsite and Its Implications to Structure-Based Drug Design Journal of Medicinal Chemistry ·Michael J. Costanzo,Harold R. Almond,Leonard R. Hecker,Eduardo Baudilio Baque Moran,Stephen C. Yabut,Han‐Cheng Zhang,Patricia Andrade‐Gordon,Anja Achtziger,Edward C. Giardino,Jack A. Kauffman,R Ham,Lawrence de Garavilla,Barbara J. Haertlein,Bruce E. Maryanoff	2004	54
12	Antiplatelet and Antithrombotic Activity of RWJ-53308, A Novel Orally Active Glycoprotein IIb/IIIa Antagonist Thrombosis Research ·Bruce P. Damiano,John A. Mitchell,Edward C. Giardino,Устьянцев Михаил Валерьевич,Barbara J. Haertlein,Lawrence de Garavilla,Jack A. Kauffman,William J. Hoekstra,Bruce E. Maryanoff,Patricia Andrade‐Gordon	2001	26
13	Administration of a Potent Antagonist of Protease-Activated Receptor-1 (PAR-1) Attenuates Vascular Restenosis Following Balloon Angioplasty in Rats Journal of Pharmacology and Experimental Therapeutics ·Patricia Andrade‐Gordon,Claudia K. Derian,Bruce E. Maryanoff,豊片野,Marylyn M. Addo,R.H. Wagoner,Bruce P. Damiano,M. R. D’Andrea,Andrew L. Darrow,Lawrence de Garavilla,Annette Eckardt,Edward C. Giardino,Barbara J. Haertlein,David F. McComsey	2001	95
14	Antithrombotic Properties of RWJ-50353, a Potent and Novel Thrombin Inhibitor* Thrombosis Research ·Edward C. Giardino,Michael J. Costanzo,Jack A. Kauffman,Lammya Kadhum Bakkir,Bruce E. Maryanoff,Patricia Andrade‐Gordon	2000	15
15	Cardiovascular Profile of RWJ 29009, a New Potassium Channel Activator, in Anesthetized and Conscious Dogs Journal of Cardiovascular Pharmacology ·Bruce P. Damiano,Edward C. Giardino,Barbara J. Haertlein,Gary L. Stump,John A. Mitchell,Robert Falotico	1994	6
16	RWJ 26629, a new potassium channel opener and vascular smooth muscle relaxant: a potential antihypertensive and antianginal agent. Journal of Pharmacology and Experimental Therapeutics ·Lawrence B. Katz,Edward C. Giardino,Joseph J. Salata,John B. Moore,Robert Falotico	1993	2
17	Novel thieno[2,3-b]- and [3,4-b]pyrans as potassium channel openers. Thiophene systems—XVII Bioorganic & Medicinal Chemistry ·Jeffery B. Press,James J. McNally,Pauline J. Sanfilippo,Marylyn M. Addo,Deborah A. Loughney,Edward C. Giardino,Laurence B. Katz,Robert Falotico,Barbara J. Haertlein	1993	2
18	Thiopene systems. 15. Synthesis and antihypertensive activity of 7- (subsituted benzamido)-6-hydroxythieno[3,2,-b]pyrans as nwe potassium channel activitors Bioorganic & Medicinal Chemistry Letters ·Pauline J. Sanfilippo,James J. McNally,Jeffery B. Press,Robert Falotico,Edward C. Giardino,Lawrence B. Katz	1993	7
19	Thiophene systems. 14. Synthesis and antihypertensive activity of novel 7-(cyclic amido)-6-hydroxythieno[3,2-b]pyrans and related compounds as new potassium channel activators Journal of Medicinal Chemistry ·Pauline J. Sanfilippo,S.S Najjar,Jeffery B. Press,Daniel Bush,Ellen,Lawrence B. Katz,Edward C. Giardino,Robert Falotico,Joseph J. Salata	1992	19
20	Renal vasodilators. The role of the 4-substituent in isoquinolin-3-ol cardiovascular agents. 4-Ureido derivatives of isoquinolin-3-ol with selective renal vasodilator properties Journal of Medicinal Chemistry ·Ramesh M. Kanojia,Хамидуллин Камиль Ринатович,Jeffery B. Press,Berggren Per-Olof,Harvey M. Werblood,Edward C. Giardino,Robert Falotico,Alfonso J. Tobia	1989	10

About Edward C. Giardino

Edward C. Giardino is a scholar working on Hematology, Internal Medicine, Cardiology and Cardiovascular Medicine, Biochemistry and Organic Chemistry, having authored 20 papers that have together received 507 indexed citations. Recurring topics across this work include Blood Coagulation and Thrombosis Mechanisms (8 papers), Chemical Synthesis and Analysis (4 papers), Click Chemistry and Applications (3 papers), Atrial Fibrillation Management and Outcomes (3 papers), Synthesis of heterocyclic compounds (2 papers), Platelet Disorders and Treatments (2 papers), Heparin-Induced Thrombocytopenia and Thrombosis (2 papers) and Synthesis and Reactivity of Sulfur-Containing Compounds (2 papers). The work is most often cited by research in Hematology (137 citations), Genetics (81 citations), Organic Chemistry (174 citations), Pharmaceutical Science (34 citations) and Internal Medicine (20 citations). Edward C. Giardino has collaborated with scholars based in United States. Frequent co-authors include Bruce E. Maryanoff, Bruce P. Damiano, Barbara J. Haertlein, Patricia Andrade‐Gordon, Lawrence de Garavilla, Jack A. Kauffman, David F. McComsey, Annette Eckardt, Claudia K. Derian and Tianbao Lu. Their work appears in journals such as Journal of Medicinal Chemistry, Bioorganic & Medicinal Chemistry Letters, Journal of Pharmacology and Experimental Therapeutics, Journal of Cardiovascular Pharmacology and Thrombosis Research.

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