Carl Crysler

1.1k citations

37 papers · 782 indexed · h-index 19

Co-authors: Bruce E. Tomczuk Carl L. Manthey Mark R. Player Tianbao Lu Renée L. DesJarlais John Spurlino Joseph J. Villafranca Wolfgang von der Saal
Topics: Blood Coagulation and Thrombosis Mechanisms (7 papers)Coagulation, Bradykinin, Polyphosphates, and Angioedema (6 papers)Cell Adhesion Molecules Research (6 papers)
Cited by: Organic Chemistry Immunology and Allergy Pharmaceutical Science
Journals: Journal of Biological Chemistry Biochemistry Journal of Medicinal Chemistry
Partner nations: United States Belgium United Kingdom

In The Last Decade

Carl Crysler

36 papers receiving 747 citations

Peers

Countries citing papers authored by Carl Crysler

Since Specialization

Citations

This map shows the geographic impact of Carl Crysler's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Carl Crysler with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Carl Crysler more than expected).

Fields of papers citing papers by Carl Crysler

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Carl Crysler. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Carl Crysler. The network helps show where Carl Crysler may publish in the future.

Co-authorship network of co-authors of Carl Crysler

This figure shows the co-authorship network connecting the top 25 collaborators of Carl Crysler. A scholar is included among the top collaborators of Carl Crysler based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Carl Crysler. Carl Crysler is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Enhancement of kinase selectivity in a potent class of arylamide FMS inhibitors 2013 ·Bioorganic & Medicinal Chemistry Letters ·Carl R. Illig,Carl L. Manthey,Sanath K. Meegalla,Mark J. Wall,(unknown),Kenneth J. Wilson,Renée L. DesJarlais,Shelley K. Ballentine,Carsten J. Schubert,Carl Crysler,Yanmin Chen,Christopher J. Molloy,Margery A. Chaikin,Robert R. Donatelli,Edward J. Yurkow,Zhou Zhao,Mark R. Player,Bruce E. Tomczuk	3
2	A novel series of N-(azetidin-3-yl)-2-(heteroarylamino)acetamide CCR2 antagonists 2012 ·Bioorganic & Medicinal Chemistry Letters ·Nalin L. Subasinghe,James C. Lanter,(unknown),Evan E. Opas,(unknown),Carl Crysler,Cuifen Hou,John O’Neill,Dana L. Johnson,Zhihua Sui	17
3	Design and synthesis of polyethylene glycol-modified biphenylsulfonyl-thiophene-carboxamidine inhibitors of the complement component C1s 2012 ·Bioorganic & Medicinal Chemistry Letters ·Nalin L. Subasinghe,Ehab M. Khalil,Jeremy Travins,(unknown),Shelley K. Ballentine,(unknown),Wenxi Pan,Kristi Leonard,Roger Bone,Richard Söll,Carl Crysler,(unknown),(unknown),(unknown),(unknown),Stephen Eisennagel,Norman Huebert,Christopher J. Molloy,Bruce E. Tomczuk,Michael D. Gaul	7
4	Overcoming hERG activity in the discovery of a series of 4-azetidinyl-1-aryl-cyclohexanes as CCR2 antagonists 2011 ·Bioorganic & Medicinal Chemistry Letters ·Xuqing Zhang,(unknown),(unknown),James C. Lanter,Chaozhong Cai,Cuifen Hou,Monica Singer,Evan E. Opas,(unknown),Carl Crysler,Dana L. Johnson,Zhihua Sui	18
5	Design, synthesis and SAR of indazole and benzoisoxazole containing 4-azetidinyl-1-aryl-cyclohexanes as CCR2 antagonists 2011 ·Bioorganic & Medicinal Chemistry Letters ·Xuqing Zhang,(unknown),Cuifen Hou,Evan E. Opas,(unknown),Carl Crysler,John O’Neill,Dana L. Johnson,Zhihua Sui	8
6	Potency variation of small-molecule chymase inhibitors across species 2010 ·Biochemical Pharmacology ·Jukka Kervinen,Carl Crysler,Shariff Bayoumy,M.C. Abad,John Spurlino,Ingrid C. Deckman,Michael N. Greco,Bruce E. Maryanoff,Lawrence de Garavilla	21
7	Reducing ion channel activity in a series of 4-heterocyclic arylamide FMS inhibitors 2010 ·Bioorganic & Medicinal Chemistry Letters ·Kenneth J. Wilson,Carl R. Illig,(unknown),Mark J. Wall,Shelley K. Ballentine,Renée L. DesJarlais,Yanmin Chen,Carsten J. Schubert,Robert R. Donatelli,Ioanna P. Petrounia,Carl Crysler,Christopher J. Molloy,Margery A. Chaikin,Carl L. Manthey,Mark R. Player,Bruce E. Tomczuk,Sanath K. Meegalla	9
8	Pyrido[2,3-d]pyrimidin-5-ones: A Novel Class of Antiinflammatory Macrophage Colony-Stimulating Factor-1 Receptor Inhibitors 2009 ·Journal of Medicinal Chemistry ·Hui Huang,(unknown),(unknown),(unknown),William H. Parsons,Carsten J. Schubert,Renée L. DesJarlais,Carl Crysler,Margery A. Chaikin,Robert R. Donatelli,Yanmin Chen,(unknown),Zhou Zhao,Edward J. Yurkow,Carl L. Manthey,Mark R. Player	36
9	Structure-based optimization of a potent class of arylamide FMS inhibitors 2008 ·Bioorganic & Medicinal Chemistry Letters ·Sanath K. Meegalla,Mark J. Wall,(unknown),Kenneth J. Wilson,Shelley K. Ballentine,Renée L. DesJarlais,Carsten J. Schubert,Carl Crysler,Yanmin Chen,Christopher J. Molloy,Margery A. Chaikin,Carl L. Manthey,Mark R. Player,Bruce E. Tomczuk,Carl R. Illig	26
10	Discovery of novel FMS kinase inhibitors as anti-inflammatory agents 2008 ·Bioorganic & Medicinal Chemistry Letters ·Carl R. Illig,(unknown),Mark J. Wall,Kenneth J. Wilson,Shelley K. Ballentine,Matthias Rudolph,Renée L. DesJarlais,Yanmin Chen,Carsten J. Schubert,Ioanna P. Petrounia,Carl Crysler,Christopher J. Molloy,Margery A. Chaikin,Carl L. Manthey,Mark R. Player,Bruce E. Tomczuk,Sanath K. Meegalla	40
11	Orally efficacious thrombin inhibitors with cyanofluorophenylacetamide as the P2 motif 2008 ·Bioorganic & Medicinal Chemistry Letters ·K. D. Kreutter,Tianbao Lu,Lily Lee,Edward C. Giardino,Sharmila Patel,Hui Huang,Guozhang Xu,Mark Fitzgerald,Barbara J. Haertlein,V. Mohan,Carl Crysler,Stephen Eisennagel,Malini Dasgupta,Martin McMillan,John Spurlino,Norman Huebert,Bruce E. Maryanoff,Bruce E. Tomczuk,Bruce P. Damiano,Mark R. Player	24
12	Carboxylic acid bioisosteres acylsulfonamides, acylsulfamides, and sulfonylureas as novel antagonists of the CXCR2 receptor 2008 ·Bioorganic & Medicinal Chemistry Letters ·Michael P. Winters,Carl Crysler,Nalin L. Subasinghe,Declan Ryan,(unknown),Shuyuan Zhao,Robert R. Donatelli,Edward J. Yurkow,(unknown),(unknown),Carl L. Manthey,Christopher J. Molloy,(unknown),Lynne A. Murray,(unknown),Bruce E. Tomczuk	28
13	2-(2-Chloro-6-fluorophenyl)acetamides as potent thrombin inhibitors 2007 ·Bioorganic & Medicinal Chemistry Letters ·Lily Lee,K. D. Kreutter,Wenxi Pan,Carl Crysler,John Spurlino,Mark R. Player,Bruce E. Tomczuk,Tianbao Lu	35
14	Novel potent and selective αvβ3/αvβ5 integrin dual antagonists with reduced binding affinity for human serum albumin 2006 ·European Journal of Medicinal Chemistry ·Pierre Raboisson,Carl L. Manthey,Margery A. Chaikin,Jennifer Lattanze,Carl Crysler,Kristi Leonard,Wenxi Pan,Bruce E. Tomczuk,Juan Marugán	10
15	The synthesis and SAR of 2-amino-pyrrolo[2,3-d]pyrimidines: A new class of Aurora-A kinase inhibitors 2006 ·Bioorganic & Medicinal Chemistry Letters ·K.J.M. Moriarty,Holly K. Koblish,Thomas Garrabrant,(unknown),Ehab M. Khalil,(unknown),Ioanna P. Petrounia,Carl Crysler,Anna C. Maroney,Dana L. Johnson,Robert A. Galemmo	54
16	A novel series of arylsulfonylthiophene-2-carboxamidine inhibitors of the complement component C1s 2006 ·Bioorganic & Medicinal Chemistry Letters ·Nalin L. Subasinghe,Jeremy Travins,(unknown),Hui Huang,Shelley K. Ballentine,Juan Marugán,Ehab M. Khalil,(unknown),Roger Bone,Renée L. DesJarlais,Carl Crysler,(unknown),Maxwell D. Cummings,Christopher J. Molloy,Bruce E. Tomczuk	11
17	Non-peptidic αvβ3 antagonists containing indol-1-yl propionic acids 2005 ·Bioorganic & Medicinal Chemistry Letters ·Kristi Leonard,Wenxi Pan,(unknown),(unknown),(unknown),Renée L. DesJarlais,(unknown),Jennifer Lattanze,Carl Crysler,Carl L. Manthey,Bruce E. Tomczuk,Juan Marugán	20
18	Oxyguanidines: application to non-peptidic phenyl-based thrombin inhibitors 2003 ·Bioorganic & Medicinal Chemistry Letters ·Bruce E. Tomczuk,Tianbao Lu,Richard Söll,(unknown),Aihua Wang,(unknown),Carl Crysler,Malini Dasgupta,Stephen Eisennagel,John Spurlino,Roger Bone	24
19	Modification of the Fc Region of a Primatized IgG Antibody to Human CD4 Retains Its Ability to Modulate CD4 Receptors but Does Not Deplete CD4+ T Cells in Chimpanzees 2001 ·Clinical Immunology ·Roland Newman,Kandasamy Hariharan,Mitchell E. Reff,(unknown),Gary R. Braslawsky,(unknown),Nabil Hanna,Peter J. Bugelski,Michael Brigham‐Burke,Carl Crysler,Robert Gagnon,(unknown),Michael L. Doyle,Preston Hensley,Manjula Reddy,Raymond W. Sweet,Alemseged Truneh	45
20	Evaluation of the Acute Hemodynamic Effects and Pharmacokinetics of Coronary Thrombolysis Produced by Intravenous Tissue-Type Plasminogen Activator in the Anesthetized Dog 1988 ·Journal of Cardiovascular Pharmacology ·Gregory A. Kopia,(unknown),K L Fong,Carl Crysler,Kathleen Boyle,Robert Ruffolo	5

About Carl Crysler

Carl Crysler is a scholar working on Immunology and Allergy, Hematology and Immunology, having authored 37 papers that have together received 782 indexed citations. Recurring topics across this work include Blood Coagulation and Thrombosis Mechanisms (7 papers), Coagulation, Bradykinin, Polyphosphates, and Angioedema (6 papers) and Cell Adhesion Molecules Research (6 papers). The work is most often cited by research in Organic Chemistry (325 citations), Immunology and Allergy (59 citations) and Pharmaceutical Science (53 citations). Carl Crysler has collaborated with scholars based in United States, Belgium and United Kingdom. Frequent co-authors include Bruce E. Tomczuk, Carl L. Manthey, Mark R. Player, Tianbao Lu, Renée L. DesJarlais, John Spurlino, Joseph J. Villafranca, Wolfgang von der Saal, Christopher J. Molloy and Margery A. Chaikin. Their work appears in journals such as Journal of Biological Chemistry, Biochemistry and Journal of Medicinal Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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