Keith T. Demarest

6.5k total citations
147 papers, 5.4k citations indexed

About

Keith T. Demarest is a scholar working on Molecular Biology, Endocrinology, Diabetes and Metabolism and Cellular and Molecular Neuroscience. According to data from OpenAlex, Keith T. Demarest has authored 147 papers receiving a total of 5.4k indexed citations (citations by other indexed papers that have themselves been cited), including 70 papers in Molecular Biology, 36 papers in Endocrinology, Diabetes and Metabolism and 33 papers in Cellular and Molecular Neuroscience. Recurrent topics in Keith T. Demarest's work include Receptor Mechanisms and Signaling (24 papers), Neuroendocrine regulation and behavior (22 papers) and Hypothalamic control of reproductive hormones (21 papers). Keith T. Demarest is often cited by papers focused on Receptor Mechanisms and Signaling (24 papers), Neuroendocrine regulation and behavior (22 papers) and Hypothalamic control of reproductive hormones (21 papers). Keith T. Demarest collaborates with scholars based in United States, Belgium and Norway. Keith T. Demarest's co-authors include Kenneth E. Moore, Kenneth E. Moore, Gail D. Riegle, Yin Liang, Lubing Zhou, Barbara R. Conway, Patricia D. Pelton, Ellen V. Cryan, Richard H. Alper and Gee‐Hong Kuo and has published in prestigious journals such as PLoS ONE, Diabetes and Analytical Biochemistry.

In The Last Decade

Keith T. Demarest

146 papers receiving 5.2k citations

Peers

Countries citing papers authored by Keith T. Demarest

Since Specialization

Citations

This map shows the geographic impact of Keith T. Demarest's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Keith T. Demarest with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Keith T. Demarest more than expected).

Fields of papers citing papers by Keith T. Demarest

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Keith T. Demarest. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Keith T. Demarest. The network helps show where Keith T. Demarest may publish in the future.

Co-authorship network of co-authors of Keith T. Demarest

This figure shows the co-authorship network connecting the top 25 collaborators of Keith T. Demarest. A scholar is included among the top collaborators of Keith T. Demarest based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Keith T. Demarest. Keith T. Demarest is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	5,5-Difluoro- and 5-Fluoro-5-methyl-hexose-based C-Glucosides as potent and orally bioavailable SGLT1 and SGLT2 dual inhibitors 2020 ·Bioorganic & Medicinal Chemistry Letters ·Guozhang Xu, Fuyong Du, Gee‐Hong Kuo, June Xu, Yin Liang, Keith T. Demarest, Michael D. Gaul	10
2	Discovery of potent and orally bioavailable indazole-based glucagon receptor antagonists for the treatment of type 2 diabetes 2019 ·Bioorganic & Medicinal Chemistry Letters ·Guozhang Xu, Michael D. Gaul, Fengbin Song, Fuyong Du, Yin Liang, Renée L. DesJarlais, (unknown), Brian C. Shook, (unknown), (unknown), Annette Eckardt, Keith T. Demarest	3
3	Design, synthesis and structure activity relationships of indazole and indole derivatives as potent glucagon receptor antagonists 2019 ·Bioorganic & Medicinal Chemistry Letters ·Fengbin Song, Guozhang Xu, Michael D. Gaul, Baoping Zhao, Tianbao Lu, Rui Zhang, Renée L. DesJarlais, (unknown), Norman Huebert, Brian C. Shook, (unknown), (unknown), Annette Eckardt, Keith T. Demarest	18
4	Synthesis and biological evaluation of benzocyclobutane-C-glycosides as potent and orally active SGLT1/SGLT2 dual inhibitors 2018 ·Bioorganic & Medicinal Chemistry Letters ·Gee‐Hong Kuo, Micheal D. Gaul, Yin Liang, June Xu, Fuyong Du, Pamela J. Hornby, Guozhang Xu, Jenson Qi, Nathaniel Wallace, Seung‐Hun Lee, Eugene B. Grant, William V. Murray, Keith T. Demarest	29
5	4-Bicyclic heteroaryl-piperidine derivatives as potent, orally bioavailable stearoyl-CoA desaturase-1 (SCD1) inhibitors: Part 2. Pyridazine-based analogs 2014 ·Bioorganic & Medicinal Chemistry Letters ·Shyh‐Ming Yang, Yuting Tang, Thomas A. Rano, (unknown), Gee‐Hong Kuo, Michael D. Gaul, Yaxin Li, (unknown), Wensheng Lang, James G. Conway, Yin Liang, James M. Lenhard, Keith T. Demarest, William V. Murray	6
6	Effect of Canagliflozin on Renal Threshold for Glucose, Glycemia, and Body Weight in Normal and Diabetic Animal Models 2012 ·PLoS ONE ·Yin Liang, Kenji Arakawa, Kiichiro Ueta, Yasuaki Matsushita, Chiaki Kuriyama, Tonya Martin, Fuyong Du, Yi Liu, June Xu, Barbara R. Conway, (unknown), David Polidori, Kirk Ways, Keith T. Demarest	200
7	Discovery of fused bicyclic agonists of the orphan G-protein coupled receptor GPR119 with in vivo activity in rodent models of glucose control 2011 ·Bioorganic & Medicinal Chemistry Letters ·Graeme Semple, Albert Ren, Beatriz Fioravanti, Guilherme Rocha Pereira, Imelda Calderon, (unknown), Yifeng Xiong, Young‐Jun Shin, Tawfik Gharbaoui, Carleton R. Sage, Michael Morgan, Charles Xing, Zhi‐Liang Chu, James Leonard, Andrew J. Grottick, (unknown), Yin Liang, Keith T. Demarest, Robert M. Jones	53
8	Discovery and SAR of para-alkylthiophenoxyacetic acids as potent and selective PPARδ agonists 2009 ·Bioorganic & Medicinal Chemistry Letters ·Rui Zhang, (unknown), Aihua Wang, Ellen Sieber-McMaster, Xun Li, Ronald K. Russell, Patricia D. Pelton, Jun Xu, Peifen Zhu, Lubing Zhou, Keith T. Demarest, William V. Murray, Gee‐Hong Kuo	8
9	Next-generation spirobenzazepines: Identification of RWJ-676070 as a balanced vasopressin V1a/V2 receptor antagonist for human clinical studies 2007 ·Bioorganic & Medicinal Chemistry Letters ·(unknown), Philip J. Rybczynski, Mona Patel, Robert H. Chen, David F. McComsey, Han‐Cheng Zhang, Joseph W. Gunnet, Richard Look, Yuanping Wang, Lisa Minor, Huailing Zhong, Frank J. Villani, Keith T. Demarest, Bruce P. Damiano, Bruce E. Maryanoff	12
10	Synthesis and structure–activity relationships of thiadiazole-derivatives as potent and orally active peroxisome proliferator-activated receptors α/δ dual agonists 2007 ·Bioorganic & Medicinal Chemistry ·Lan Shen, Yan Zhang, Aihua Wang, Ellen Sieber-McMaster, Xiaoli Chen, Patricia D. Pelton, June Xu, Maria Yang, Peifen Zhu, Lubing Zhou, Michael Reuman, (unknown), Ronald K. Russell, Alan C. Gibbs, (unknown), Keith T. Demarest, William V. Murray, Gee‐Hong Kuo	21
11	CHARACTERIZATION OF RWJ‐351647, A NOVEL NONPEPTIDE VASOPRESSIN V₂RECEPTOR ANTAGONIST 2006 ·Clinical and Experimental Pharmacology and Physiology ·Joseph W. Gunnet, Jay M. Matthews, Bruce E. Maryanoff, Lawrence de Garavilla, Patricia Andrade‐Gordon, Bruce P. Damiano, William Hageman, Richard Look, (unknown), Anthony J. Streeter, (unknown), Keith T. Demarest	8
12	Enhancement of arachidonic acid signaling pathway by nicotinic acid receptor HM74A 2006 ·Biochemical and Biophysical Research Communications ·Yuting Tang, Lubing Zhou, Joseph W. Gunnet, (unknown), Ellen V. Cryan, Keith T. Demarest	46
13	Novel phosphorus-containing 17β-side chain mifepristone analogues as progesterone receptor antagonists 2006 ·Steroids ·Weiqin Jiang, George F. Allan, Xin Chen, (unknown), Olivia Linton, Pamela L. Tannenbaum, Jun Xu, Peifen Zhu, Joseph W. Gunnet, Keith T. Demarest, Scott G. Lundeen, Zhihua Sui	21
14	Design, synthesis, and biological evaluation of novel 7-azaindolyl-heteroaryl-maleimides as potent and selective glycogen synthase kinase-3β (GSK-3β) inhibitors 2004 ·Bioorganic & Medicinal Chemistry ·David J. O’Neill, Lan Shen, Catherine Prouty, Barbara R. Conway, Lori Westover, Jun Xu, Han‐Cheng Zhang, Bruce E. Maryanoff, William V. Murray, Keith T. Demarest, Gee‐Hong Kuo	41
15	Development of a Sensitive and HTS-Compatible Reporter Gene Assay for Functional Analysis of Human Adenosine A2a Receptors in CHO-K1 Cells 2004 ·Assay and Drug Development Technologies ·Yuting Tang, Jing-Qing Luo, (unknown), Yan Kong, Gilbert C. Olini, Mary Jo Wildey, Druie Cavender, Keith T. Demarest	7
16	Synthesis and evaluation of nonpeptide substituted spirobenzazepines as potent vasopressin antagonists 2004 ·Bioorganic & Medicinal Chemistry Letters ·(unknown), Robert H. Chen, Keith T. Demarest, Joseph W. Gunnet, Richard Look, William Hageman, William V. Murray, Donald W. Combs, Philip J. Rybczynski, Mona Patel	4
17	2,5-Disubstituted 3,4-dihydro-2H-benzo[b][1,4]thiazepines as potent and selective V2 arginine vasopressin receptor antagonists 2003 ·Bioorganic & Medicinal Chemistry Letters ·(unknown), Robert H. Chen, Keith T. Demarest, Joseph W. Gunnet, Richard Look, (unknown), William V. Murray, Philip J. Rybczynski, Xiaoyan Zhang	32
18	Macrocyclic bisindolylmaleimides as inhibitors of protein kinase C and glycogen synthase kinase-3 2003 ·Bioorganic & Medicinal Chemistry Letters ·Han‐Cheng Zhang, (unknown), Hong Ye, David F. McComsey, Claudia K. Derian, Marylyn M. Addo, Patricia Andrade‐Gordon, Annette Eckardt, Barbara R. Conway, Lori Westover, Jun Xu, Richard Look, Keith T. Demarest, Stuart L. Emanuel, Bruce E. Maryanoff	52
19	Benzoxazinones as PPARγ agonists. part 1: SAR of three aromatic regions 2003 ·Bioorganic & Medicinal Chemistry Letters ·Philip J. Rybczynski, (unknown), Donald W. Combs, Ignatius J. Turchi, Thomas P. Burris, Jun Xu, Maria Yang, Keith T. Demarest	16
20	In vitro permeability of eight β-blockers through Caco-2 monolayers utilizing liquid chromatography/electrospray ionization mass spectrometry 1998 ·Journal of Mass Spectrometry ·Gary W. Caldwell, (unknown), Joseph W. Gunnet, John A. Masucci, Keith T. Demarest	35

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