John Spurlino

4.0k total citations
42 papers, 2.8k citations indexed

About

John Spurlino is a scholar working on Molecular Biology, Organic Chemistry and Oncology. According to data from OpenAlex, John Spurlino has authored 42 papers receiving a total of 2.8k indexed citations (citations by other indexed papers that have themselves been cited), including 19 papers in Molecular Biology, 12 papers in Organic Chemistry and 9 papers in Oncology. Recurrent topics in John Spurlino's work include Peptidase Inhibition and Analysis (9 papers), Chemical Synthesis and Analysis (8 papers) and Protease and Inhibitor Mechanisms (6 papers). John Spurlino is often cited by papers focused on Peptidase Inhibition and Analysis (9 papers), Chemical Synthesis and Analysis (8 papers) and Protease and Inhibitor Mechanisms (6 papers). John Spurlino collaborates with scholars based in United States, United Kingdom and France. John Spurlino's co-authors include Florante A. Quiocho, Lynn E. Rodseth, Andrew Sharff, Roger Bone, Douglas L. Smith, Robert C. Wahl, Tracey M. Banks, F. Raymond Salemme, Bruce E. Tomczuk and Richard Söll and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Journal of Molecular Biology.

In The Last Decade

John Spurlino

42 papers receiving 2.7k citations

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
John Spurlino United States 24 1.6k 707 538 485 432 42 2.8k
Ward W. Smith United States 28 2.0k 1.2× 534 0.8× 583 1.1× 211 0.4× 506 1.2× 38 3.4k
Richard A. Pauptit United Kingdom 25 1.8k 1.1× 460 0.7× 558 1.0× 179 0.4× 526 1.2× 42 2.6k
Steven R. Jordan United States 24 2.2k 1.3× 280 0.4× 501 0.9× 406 0.8× 247 0.6× 46 3.2k
F.K. Winkler Switzerland 18 2.5k 1.5× 350 0.5× 432 0.8× 385 0.8× 453 1.0× 32 4.1k
F. Niesen United Kingdom 19 2.7k 1.6× 443 0.6× 422 0.8× 261 0.5× 211 0.5× 25 3.5k
John S. Sack United States 27 2.2k 1.3× 592 0.8× 370 0.7× 503 1.0× 488 1.1× 53 3.5k
L.H. Weaver United States 31 2.7k 1.7× 1.1k 1.6× 553 1.0× 280 0.6× 475 1.1× 42 3.8k
Michael Hennig Switzerland 38 3.2k 1.9× 757 1.1× 735 1.4× 147 0.3× 620 1.4× 88 4.9k
Petr Kuzmič United States 26 2.3k 1.4× 420 0.6× 569 1.1× 188 0.4× 471 1.1× 65 3.5k
Trevor J. Rutherford United Kingdom 35 3.7k 2.2× 543 0.8× 913 1.7× 185 0.4× 719 1.7× 87 4.6k

Countries citing papers authored by John Spurlino

Since Specialization
Citations

This map shows the geographic impact of John Spurlino's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by John Spurlino with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites John Spurlino more than expected).

Fields of papers citing papers by John Spurlino

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by John Spurlino. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by John Spurlino. The network helps show where John Spurlino may publish in the future.

Co-authorship network of co-authors of John Spurlino

This figure shows the co-authorship network connecting the top 25 collaborators of John Spurlino. A scholar is included among the top collaborators of John Spurlino based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with John Spurlino. John Spurlino is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Gege, Christian, M. Albers, Olaf Kinzel, et al.. (2020). Optimization and biological evaluation of thiazole-bis-amide inverse agonists of RORγt. Bioorganic & Medicinal Chemistry Letters. 30(12). 127205–127205. 10 indexed citations
2.
Xu, Guozhang, Michael D. Gaul, Zhi‐Jie Liu, et al.. (2020). Hit-to-lead optimization and discovery of a potent, and orally bioavailable G protein coupled receptor kinase 2 (GRK2) inhibitor. Bioorganic & Medicinal Chemistry Letters. 30(23). 127602–127602. 3 indexed citations
3.
Spurlino, John. (2011). Fragment Screening Purely with Protein Crystallography. Methods in enzymology on CD-ROM/Methods in enzymology. 493. 321–356. 20 indexed citations
4.
Tresadern, Gary, Francisca Delgado, Óscar Delgado, et al.. (2011). Rational design and synthesis of aminopiperazinones as β-secretase (BACE) inhibitors. Bioorganic & Medicinal Chemistry Letters. 21(24). 7255–7260. 36 indexed citations
5.
Kervinen, Jukka, Carl Crysler, Shariff Bayoumy, et al.. (2010). Potency variation of small-molecule chymase inhibitors across species. Biochemical Pharmacology. 80(7). 1033–1041. 21 indexed citations
6.
Kreutter, K. D., Tianbao Lu, Lily Lee, et al.. (2008). Orally efficacious thrombin inhibitors with cyanofluorophenylacetamide as the P2 motif. Bioorganic & Medicinal Chemistry Letters. 18(9). 2865–2870. 24 indexed citations
7.
Abad, M.C., John O’Neill, Alexandra L. Klinger, et al.. (2007). Structural determination of estrogen-related receptor γ in the presence of phenol derivative compounds. The Journal of Steroid Biochemistry and Molecular Biology. 108(1-2). 44–54. 49 indexed citations
8.
Schubert, Carsten J., Céline Schalk‐Hihi, Geoffrey T. Struble, et al.. (2006). Crystal Structure of the Tyrosine Kinase Domain of Colony-stimulating Factor-1 Receptor (cFMS) in Complex with Two Inhibitors. Journal of Biological Chemistry. 282(6). 4094–4101. 56 indexed citations
9.
Alexander, Richard & John Spurlino. (2005). Structural Biology in Early Phase Drug Discovery. 1(1). 287–296. 3 indexed citations
10.
Tomczuk, Bruce E., Tianbao Lu, Richard Söll, et al.. (2003). Oxyguanidines: application to non-peptidic phenyl-based thrombin inhibitors. Bioorganic & Medicinal Chemistry Letters. 13(8). 1495–1498. 24 indexed citations
11.
Rudolph, Matthias, Carl R. Illig, Nalin L. Subasinghe, et al.. (2002). Design and Synthesis of 4,5-Disubstituted-thiophene-2-amidines as Potent Urokinase Inhibitors. Bioorganic & Medicinal Chemistry Letters. 12(3). 491–495. 23 indexed citations
12.
Söll, Richard, Bruce E. Tomczuk, Carl R. Illig, et al.. (2000). Amidinohydrazones as guanidine bioisosteres: application to a new class of potent, selective and orally bioavailable, non-amide-based small-molecule thrombin inhibitors. Bioorganic & Medicinal Chemistry Letters. 10(1). 1–4. 33 indexed citations
13.
Lu, Tianbao, Bruce E. Tomczuk, Carl R. Illig, et al.. (1998). In vitro evaluation and crystallographic analysis of a new class of selective, non-amide-based thrombin inhibitors. Bioorganic & Medicinal Chemistry Letters. 8(13). 1595–1600. 20 indexed citations
14.
Salemme, F. Raymond, John Spurlino, & Roger Bone. (1997). Serendipity meets precision: the integration of structure-based drug design and combinatorial chemistry for efficient drug discovery. Structure. 5(3). 319–324. 53 indexed citations
15.
Quiocho, Florante A., John Spurlino, & Lynn E. Rodseth. (1997). Extensive features of tight oligosaccharide binding revealed in high-resolution structures of the maltodextrin transport/chemosensory receptor. Structure. 5(8). 997–1015. 280 indexed citations
16.
Gowravaram, Madhusudhan, Jeffrey S. Johnson, Ewell R. Cook, et al.. (1995). Inhibition of Matrix Metalloproteinases by Hydroxamates Containing Heteroatom-Based Modifications of the P1' Group. Journal of Medicinal Chemistry. 38(14). 2570–2581. 48 indexed citations
17.
Guevara, Juan, John Spurlino, Chao Yang, et al.. (1993). Proposed mechanisms for binding of apo[a] kringle type 9 to apo B-100 in human lipoprotein[a]. Biophysical Journal. 64(3). 686–700. 60 indexed citations
18.
Spurlino, John, Lynn E. Rodseth, & Florante A. Quiocho. (1992). Atomic interactions in protein-carbohydrate complexes. Journal of Molecular Biology. 226(1). 15–22. 43 indexed citations
19.
Guevara, Juan, Roger D. Knapp, John Spurlino, B. V. Venkataram Prasad, & Joel D. Morrisett. (1992). Method for calculating 3-D coordinates from molecular stereograms. Journal of Protein Chemistry. 11(6). 653–656. 1 indexed citations
20.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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