John E. Toth

1.1k citations

30 papers · 793 indexed · h-index 14

Cell Biology top 10%
Organic Chemistry top 10%
- Synthesis and Characterization of Heterocyclic Compounds 3
- Synthesis and biological activity 3
- Carbohydrate Chemistry and Synthesis 3
Oncology
- Cancer-related Molecular Pathways 3
Molecular Biology
- Phenothiazines and Benzothiazines Synthesis and Activities 4
Physiology top 10%
Pharmacology
- Microbial Natural Products and Biosynthesis 3
- Pharmacogenetics and Drug Metabolism 3
Microbiology
- Microbial infections and disease research 3

Co-authors: James E. Ray Richard M. Schultz Herbert A. Kirst John F. Worzalla Pamela Rutherford Gerald B. Grindey Chris J. Vlahos Richard P. Beckmann
Cited by: Cell Biology Organic Chemistry Oncology
Journals: The Journal of Antibiotics (7 papers)Journal of Medicinal Chemistry (5 papers)Bioorganic & Medicinal Chemistry Letters (2 papers)
Partner nations: United States Canada France

In The Last Decade

John E. Toth

29 papers receiving 762 citations

Peers

Countries citing papers authored by John E. Toth

Since Specialization

Citations

This map shows the geographic impact of John E. Toth's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by John E. Toth with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites John E. Toth more than expected).

Fields of papers citing papers by John E. Toth

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by John E. Toth. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by John E. Toth. The network helps show where John E. Toth may publish in the future.

Co-authorship network

The 25 scholars most cited alongside John E. Toth, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with John E. Toth Line = papers co-authored together John E. Toth links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Cdk1 Activity Is Required for Mitotic Activation of Aurora A during G2/M Transition of Human Cells Journal of Biological Chemistry ·Robert D. Van Horn,Shaoyou Chu,Fan Li,Tinggui Yin,Jian Du,Richard P. Beckmann,Mary M. Mader,Guoxin Zhu,John E. Toth,Kerry Blanchard,Xiang S. Ye	2010	62
2	A concise synthesis of quinazolinone TGF-β RI inhibitor through one-pot three-component Suzuki–Miyaura/etherification and imidate–amide rearrangement reactions Tetrahedron ·Hongyu Li,Yan Wang,William T. McMillen,Arindam Chatterjee,John E. Toth,Madhu Thota,Matthew E. Voss,Robert D. Boyer,J. Scott Sawyer	2007	15
3	Mitotic requirement for aurora A kinase is bypassed in the absence of aurora B kinase FEBS Letters ·Hui Yang,Teresa F. Burke,Jack Dempsey,Bruce Diaz,Elizabeth Collins,John E. Toth,Richard P. Beckmann,Xiang Ye	2005	86
4	Complete Inhibition of Anisomycin and UV Radiation but Not Cytokine Induced JNK and p38 Activation by an Aryl-substituted Dihydropyrrolopyrazole Quinoline and Mixed Lineage Kinase 7 Small Interfering RNA Journal of Biological Chemistry ·Xushan Wang,Mary M. Mader,John E. Toth,ERIC H. BEVERSLUIS,Najia Jin,Robert M. Campbell,Jeffrey K. Smallwood,Michael E. Christe,Arindam Chatterjee,Theodore Goodson,Chris J. Vlahos,William F. Matter,Laura J. Bloem	2005	69
5	Synthesis and In Vitro Antimicrobial Activity of 3-Keto 16-Membered Macrolides Derived From Tylosin. The Journal of Antibiotics ·Lawrence C. Creemer,John E. Toth,Herbert A. Kirst	2002	11
6	ChemInform Abstract: Synthesis and Structure—Activity Relationship Studies of Cryptophycins: A Novel Class of Potent Antimitotic Antitumor Depsipeptides ChemInform ·Chuan Shih,Rima Al‐awar,W. Mertens,Michael J. Martinelli,Eric D. Moher,Bryan H. Norman,Vinod F. Patel,Richard M. Schultz,John E. Toth,David L. Varie,(unknown)	2002	2
7	Structures of Three Inhibitor Complexes Provide Insight into the Reaction Mechanism of the Human Methylenetetrahydrofolate Dehydrogenase/Cyclohydrolase Biochemistry ·Andrea Schmidt,Haiping Wu,Robert E. MacKenzie,Victor J. Chen,Ahmad Ali Al. Syouf,James E. Ray,John E. Toth,Mirosław Cygler	2000	46
8	Synthesis and biological evaluation of cryptophycin analogs with substitution at C-6 (fragment C region) Bioorganic & Medicinal Chemistry Letters ·David L. Varie,Chuan Shih,David Hay,Sherri L. Andis,Lin Yaomin,Lynn S. Gossett,Zhiping Peng,Michael J. Martinelli,Eric D. Moher,Richard M. Schultz,John E. Toth	1999	31
9	The Antiproliferative and Cell Cycle Effects of 5,6,7,8-Tetrahydro-N5,N10-Carbonylfolic Acid, an Inhibitor of Methylenetetrahydrofolate Dehydrogenase, Are Potentiated by Hypoxanthine Journal of Pharmacology and Experimental Therapeutics ·John L. Tonkinson,Lillian L. Habeck,John E. Toth,Laurane G. Mendelsohn,Jesse R. Bewley,Katherine A. Shackelford,Susan B. Gates,James E. Ray,Victor J. Chen	1998	11
10	Sulfonimidamide Analogs of Oncolytic Sulfonylureas^,1 Journal of Medicinal Chemistry ·John E. Toth,Gerald B. Grindey,William J. Ehlhardt,James E. Ray,George B. Boder,Jesse R. Bewley,L. Frisari,Susan B. Gates,Sharon M. Rinzel,Richard M. Schultz,Leonard C. Weir,John F. Worzalla	1997	90
11	Disposition and metabolism of the sulfonylurea oncolytic agent LY295501 in mouse, rat, and monkey. PubMed ·William J. Ehlhardt,罗玫,John E. Toth,James E. Ray,Diana L. Martin	1997	8
12	Efficacy of sulofenur and a second generation diarylsulfonylurea, N-[5-(2,3-dihydrobenzofuryl) sulfonyl]-N'-(3,4-dichlorophenyl)urea (LY295501), against colon adenocarcinoma xenografts Anti-Cancer Drugs ·Peter J. Houghton,Pamela J. Cheshire,Leann Myers,Haniyah Indayani,John E. Toth,Gerald B. Grindey,Janet A. Houghton	1995	10
13	Evaluation of new anticancer agents against the MIA PaCa-2 and PANC-1 human pancreatic carcinoma xenografts. PubMed ·Richard M. Schultz,Ronald L. Merriman,John E. Toth,Johannes Zimmermann,Larry W. Hertel,Sherri L. Andis,Laurel Claude,Pamela Rutherford,Lee R. Tanzer,Gerald B. Grindey	1993	57
14	Synthesis and resolution of sulfonimidamide analogs of sulfonylureas The Journal of Organic Chemistry ·John E. Toth,James E. Ray,Jack B. Deeter	1993	10
15	Effects of diarylsulfonylurea antitumor agents on the function of mitochondria isolated from rat liver and GC3/c1 cells Biochemical Pharmacology ·Glenn F. Rush,Sharon M. Rinzel,Bernard Lenrow,Roger Heim,John E. Toth,Amanda Tomes	1992	36
16	Comparison of metabolism and toxicity to the structure of the anticancer agent sulofenur and related sulfonylureas Chemical Research in Toxicology ·William J. Ehlhardt,罗玫,John F. Worzalla,Jesse R. Bewley,Gerald B. Grindey,Glen C. Todd,John E. Toth,J. Jeffry Howbert	1992	13
17	Structure-activity studies of 20-deoxo-20-amino derivatives of tylosin-related macrolides. The Journal of Antibiotics ·Herbert A. Kirst,M. H. B. P. Madana,Manuel Debono,John E. Toth,A. Jafari Ramiani,Anne Manton,J. L. OTT,J.K. Fidler,F. T. COUNTER,E. E. Ose,Gary D. Crouse,J. M. Tustin,Satoshi Ōmura	1989	12
18	Synthesis and evaluation of tylosin-related macrolides modified at the aldehyde function: a new series of orally effective antibiotics Journal of Medicinal Chemistry ·Herbert A. Kirst,John E. Toth,Manuel Debono,M. H. B. P. Madana,A. Jafari Ramiani,J. L. OTT,F. T. COUNTER,J.K. Fidler,Robert S. Pekarek	1988	31
19	In vitro and in vivo evaluation of C-20- and C-23-modified derivatives of tylosin against veterinary pathogens. The Journal of Antibiotics ·Herbert A. Kirst,E. E. Ose,John E. Toth,M. H. B. P. Madana,Manuel Debono,J.K. Fidler,R. S. Pekarek	1988	8
20	Control of site-specific substitution of aminoglycosides by transition metal cations Tetrahedron Letters ·Herbert A. Kirst,A. Jafari Ramiani,John E. Toth	1981	16

About John E. Toth

John E. Toth is a scholar working on Microbiology, Organic Chemistry, Molecular Medicine, Pharmacology and Pharmacology, having authored 30 papers that have together received 793 indexed citations. Recurring topics across this work include Phenothiazines and Benzothiazines Synthesis and Activities (4 papers), Synthesis and Characterization of Heterocyclic Compounds (3 papers), Synthesis and biological activity (3 papers), Microbial Natural Products and Biosynthesis (3 papers), Pharmacogenetics and Drug Metabolism (3 papers), Microbial infections and disease research (3 papers), Cancer-related Molecular Pathways (3 papers) and Carbohydrate Chemistry and Synthesis (3 papers). The work is most often cited by research in Cell Biology (147 citations), Organic Chemistry (245 citations), Oncology (185 citations), Molecular Biology (464 citations) and Physiology (28 citations). John E. Toth has collaborated with scholars based in United States, Canada and France. Frequent co-authors include James E. Ray, Richard M. Schultz, Herbert A. Kirst, John F. Worzalla, Pamela Rutherford, Gerald B. Grindey, Chris J. Vlahos, Richard P. Beckmann, Sharon M. Rinzel and Chuan Shih. Their work appears in journals such as The Journal of Antibiotics, Journal of Medicinal Chemistry, Bioorganic & Medicinal Chemistry Letters, Journal of Biological Chemistry and Journal of Pharmacology and Experimental Therapeutics.

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