Melissa Dumble

1.8k total citations
28 papers, 1.3k citations indexed

About

Melissa Dumble is a scholar working on Molecular Biology, Oncology and Cancer Research. According to data from OpenAlex, Melissa Dumble has authored 28 papers receiving a total of 1.3k indexed citations (citations by other indexed papers that have themselves been cited), including 17 papers in Molecular Biology, 15 papers in Oncology and 6 papers in Cancer Research. Recurrent topics in Melissa Dumble's work include Cancer-related Molecular Pathways (11 papers), RNA modifications and cancer (5 papers) and Cancer, Hypoxia, and Metabolism (4 papers). Melissa Dumble is often cited by papers focused on Cancer-related Molecular Pathways (11 papers), RNA modifications and cancer (5 papers) and Cancer, Hypoxia, and Metabolism (4 papers). Melissa Dumble collaborates with scholars based in United States, Australia and Japan. Melissa Dumble's co-authors include George C. Yeoh, Emma Croager, Lawrence A. Donehower, Elizabeth Quail, Lynette M. Moore, Belinda Knight, Margaret A. Goodell, Gary Van Zant, Stuart M. Chambers and Hartmut Geiger and has published in prestigious journals such as Blood, PLoS ONE and Hepatology.

In The Last Decade

Melissa Dumble

28 papers receiving 1.3k citations

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Melissa Dumble United States 17 749 411 271 244 203 28 1.3k
Tomohiko Sakabe Japan 17 475 0.6× 248 0.6× 171 0.6× 197 0.8× 163 0.8× 43 991
Sunbin Ling China 19 790 1.1× 533 1.3× 232 0.9× 402 1.6× 167 0.8× 50 1.4k
Chris K. Sun Hong Kong 23 791 1.1× 299 0.7× 333 1.2× 316 1.3× 197 1.0× 25 1.4k
Michiya Kawaguchi Japan 14 794 1.1× 680 1.7× 254 0.9× 257 1.1× 557 2.7× 25 1.8k
Joanna W. Ho Hong Kong 15 638 0.9× 283 0.7× 346 1.3× 281 1.2× 114 0.6× 16 1.1k
Laia Caja Sweden 23 1.1k 1.5× 744 1.8× 281 1.0× 434 1.8× 152 0.7× 39 1.9k
Masaharu Furutani Japan 18 366 0.5× 258 0.6× 286 1.1× 244 1.0× 237 1.2× 26 892
Thomas Amann Germany 17 806 1.1× 238 0.6× 284 1.0× 452 1.9× 126 0.6× 28 1.4k
Yongchang Shi United States 7 578 0.8× 535 1.3× 260 1.0× 211 0.9× 77 0.4× 9 1.3k
Ronald E. Savage United States 20 632 0.8× 341 0.8× 332 1.2× 141 0.6× 205 1.0× 43 1.3k

Countries citing papers authored by Melissa Dumble

Since Specialization
Citations

This map shows the geographic impact of Melissa Dumble's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Melissa Dumble with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Melissa Dumble more than expected).

Fields of papers citing papers by Melissa Dumble

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Melissa Dumble. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Melissa Dumble. The network helps show where Melissa Dumble may publish in the future.

Co-authorship network of co-authors of Melissa Dumble

This figure shows the co-authorship network connecting the top 25 collaborators of Melissa Dumble. A scholar is included among the top collaborators of Melissa Dumble based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Melissa Dumble. Melissa Dumble is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Vu, Binh Thanh, Romyr Dominique, Bruce J. Fahr, et al.. (2024). Discovery of Rezatapopt (PC14586), a First-in-Class, Small-Molecule Reactivator of p53 Y220C Mutant in Development. ACS Medicinal Chemistry Letters. 16(1). 34–39. 11 indexed citations
2.
Narasimhan, Jana, Aleksey I. Gerasyuto, Jiashi Wang, et al.. (2022). Ribonucleotide reductase, a novel drug target for gonorrhea. DSpace@MIT (Massachusetts Institute of Technology). 8 indexed citations
3.
Dumble, Melissa, Lizhong Xu, Romyr Dominique, et al.. (2021). Abstract LB006: PC14586: The first orally bioavailable small molecule reactivator of Y220C mutant p53 in clinical development. Cancer Research. 81(13_Supplement). LB006–LB006. 23 indexed citations
4.
Dey, Anindya, Xunhao Xiong, Shailendra Kumar Dhar Dwivedi, et al.. (2017). Evaluating the Mechanism and Therapeutic Potential of PTC-028, a Novel Inhibitor of BMI-1 Function in Ovarian Cancer. Molecular Cancer Therapeutics. 17(1). 39–49. 31 indexed citations
5.
Nishida, Yuichiro, Long Cao, Yasushi Kubota, et al.. (2017). The novel BMI-1 inhibitor PTC596 downregulates MCL-1 and induces p53-independent mitochondrial apoptosis in acute myeloid leukemia progenitor cells. Blood Cancer Journal. 7(2). e527–e527. 62 indexed citations
6.
Dumble, Melissa, Ming‐Chih Crouthamel, Shuyun Zhang, et al.. (2014). Discovery of Novel AKT Inhibitors with Enhanced Anti-Tumor Effects in Combination with the MEK Inhibitor. PLoS ONE. 9(6). e100880–e100880. 116 indexed citations
7.
Zhang, Yixian, Stephen Castaneda, Melissa Dumble, et al.. (2011). Reduced Expression of the Androgen Receptor by Third Generation of Antisense Shows Antitumor Activity in Models of Prostate Cancer. Molecular Cancer Therapeutics. 10(12). 2309–2319. 41 indexed citations
8.
Terzian, Tamara, Melissa Dumble, Christina Thaller, et al.. (2011). Rpl27a mutation in the sooty foot ataxia mouse phenocopies high p53 mouse models. The Journal of Pathology. 224(4). 540–552. 22 indexed citations
9.
Sapra, Puja, Patricia Kraft, Fabio Pastorino, et al.. (2011). Potent and sustained inhibition of HIF-1α and downstream genes by a polyethyleneglycol-SN38 conjugate, EZN-2208, results in anti-angiogenic effects. Angiogenesis. 14(3). 245–53. 61 indexed citations
10.
Merritt, William M., Alpa M. Nick, Amy R. Carroll, et al.. (2010). Bridging the Gap between Cytotoxic and Biologic Therapy with Metronomic Topotecan and Pazopanib in Ovarian Cancer. Molecular Cancer Therapeutics. 9(4). 985–995. 47 indexed citations
11.
Dumble, Melissa, et al.. (2010). 53 Down regulation of beta-catenin by a locked nucleic acid oligonucleotide antagonist inhibits tumor growth in experimental models of human cancer. European Journal of Cancer Supplements. 8(7). 26–26. 1 indexed citations
12.
Sabbatini, Peter, Susan Korenchuk, Jason L. Rowand, et al.. (2009). GSK1838705A inhibits the insulin-like growth factor-1 receptor and anaplastic lymphoma kinase and shows antitumor activity in experimental models of human cancers. Molecular Cancer Therapeutics. 8(10). 2811–2820. 86 indexed citations
13.
Sabbatini, Peter, Jason L. Rowand, Arthur Groy, et al.. (2009). Antitumor Activity of GSK1904529A, a Small-molecule Inhibitor of the Insulin-like Growth Factor-I Receptor Tyrosine Kinase. Clinical Cancer Research. 15(9). 3058–3067. 62 indexed citations
14.
Rabindran, Sridhar K., Peter Sabbatini, Susan Korenchuk, et al.. (2009). Abstract #1740: Characterization of GSK1838705A, a small molecule inhibitor of the insulin-like growth factor-1 receptor and anaplastic lymphoma kinase that delays growth of IGF-1R-dependent tumors and causes regression of ALK-dependent tumors in vivo. Cancer Research. 69. 1740–1740. 2 indexed citations
15.
Gatza, Catherine E., Melissa Dumble, Frances Kittrell, et al.. (2007). Altered mammary gland development in the p53+/m mouse, a model of accelerated aging. Developmental Biology. 313(1). 130–141. 29 indexed citations
16.
Gatza, Catherine E., Lynette M. Moore, Melissa Dumble, & Lawrence A. Donehower. (2007). Tumor Suppressor Dosage Regulates Stem Cell Dynamics during Aging. Cell Cycle. 6(1). 52–55. 26 indexed citations
17.
Lu, Xiongbin, Melissa Dumble, Thuy‐Ai Nguyen, et al.. (2006). Augmented cancer resistance and DNA damage response phenotypes in PPM1D null mice. Molecular Carcinogenesis. 45(8). 594–604. 61 indexed citations
18.
Dumble, Melissa, Lynette M. Moore, Stuart M. Chambers, et al.. (2006). The impact of altered p53 dosage on hematopoietic stem cell dynamics during aging. Blood. 109(4). 1736–1742. 190 indexed citations
19.
Dumble, Melissa, Lawrence A. Donehower, & Xiongbin Lu. (2003). Generation and Characterization of p53 Mutant Mice. Humana Press eBooks. 234. 29–50. 9 indexed citations
20.
Dumble, Melissa, Emma Croager, George C. Yeoh, & Elizabeth Quail. (2002). Generation and characterization of p53 null transformed hepatic progenitor cells: oval cells give rise to hepatocellular carcinoma. Carcinogenesis. 23(3). 435–445. 176 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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