David C. Myles

2.9k total citations
75 papers, 2.3k citations indexed

About

David C. Myles is a scholar working on Organic Chemistry, Molecular Biology and Oncology. According to data from OpenAlex, David C. Myles has authored 75 papers receiving a total of 2.3k indexed citations (citations by other indexed papers that have themselves been cited), including 40 papers in Organic Chemistry, 34 papers in Molecular Biology and 27 papers in Oncology. Recurrent topics in David C. Myles's work include Synthetic Organic Chemistry Methods (24 papers), Cancer Treatment and Pharmacology (20 papers) and Microbial Natural Products and Biosynthesis (10 papers). David C. Myles is often cited by papers focused on Synthetic Organic Chemistry Methods (24 papers), Cancer Treatment and Pharmacology (20 papers) and Microbial Natural Products and Biosynthesis (10 papers). David C. Myles collaborates with scholars based in United States, South Korea and Italy. David C. Myles's co-authors include George M. Whitesides, Robin L. Garrell, Ge Yang, Catherine F. Clarke, Yoshihiro Kobori, Wayne W. Poon, Samuel J. Danishefsky, Scott S. Harried, Yaoquan Liu and Robert Barkovich and has published in prestigious journals such as Journal of the American Chemical Society, Journal of Biological Chemistry and Nature Communications.

In The Last Decade

David C. Myles

74 papers receiving 2.2k citations

Peers

Countries citing papers authored by David C. Myles

Since Specialization

Citations

This map shows the geographic impact of David C. Myles's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David C. Myles with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David C. Myles more than expected).

Fields of papers citing papers by David C. Myles

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David C. Myles. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David C. Myles. The network helps show where David C. Myles may publish in the future.

Co-authorship network of co-authors of David C. Myles

This figure shows the co-authorship network connecting the top 25 collaborators of David C. Myles. A scholar is included among the top collaborators of David C. Myles based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with David C. Myles. David C. Myles is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Palazestrant (OP-1250), A Complete Estrogen Receptor Antagonist, Inhibits Wild-type and Mutant ER-positive Breast Cancer Models as Monotherapy and in Combination 2023 ·Molecular Cancer Therapeutics ·(unknown), (unknown), Leslie Hodges-Gallagher, Fabian E. Ortega, (unknown), (unknown), (unknown), (unknown), David Kulp, Gopinath S. Palanisamy, David C. Myles, Peter J. Kushner, Cyrus L. Harmon	21
2	Abstract P1-17-12: Preliminary data from a phase I/II, multicenter, dose escalation study of OP-1250, an oral CERAN/SERD, in subjects with advanced and/or metastatic estrogen receptor (ER)-positive, HER2-negative breast cancer 2022 ·Cancer Research ·Manish R. Patel, Carlos Alemany, Zahi Mitri, Della Makower, Virginia F. Borges, Joseph A. Sparano, (unknown), Pamela Klein, Julia Lawrence, Peter J. Kushner, (unknown), Cyrus L. Harmon, David C. Myles, JoAnne Zujewski, Erika Hamilton	17
3	OP-1250: A potent orally available complete antagonist of estrogen receptor-mediated signaling that shrinks wild type and mutant breast tumors 2020 ·European Journal of Cancer ·Leslie Hodges-Gallagher, (unknown), David C. Myles, Pamela Klein, J. Zujewski, Cyrus L. Harmon, Peter J. Kushner	7
4	The role of the 4′′-hydroxyl on motilin agonist potency in the 9-dihydroerythromycin series 2011 ·Bioorganic & Medicinal Chemistry Letters ·Yaoquan Liu, Christopher W. Carreras, (unknown), David C. Myles, Simon J. Shaw	3
5	9-Dihydroerythromycins as non-antibiotic motilin receptor agonists 2010 ·Bioorganic & Medicinal Chemistry Letters ·Yaoquan Liu, Yong Li, Yue Chen, Hao Zheng, (unknown), David C. Myles, Christopher W. Carreras	3
6	9-Dihydroerythromycin ethers as motilin agonists—Developing structure–activity relationships for potency and safety 2010 ·Bioorganic & Medicinal Chemistry ·Yaoquan Liu, Yong Li, David C. Myles, (unknown), Christopher W. Carreras, Simon J. Shaw	4
7	Investigating Amine Derivatives of Ambruticin VS‐5 and VS‐4 2008 ·ChemMedChem ·Zong‐Qiang Tian, Zhan Wang, (unknown), (unknown), David C. Myles, Ziyang Zhong, Jessica K. Simmons, (unknown), Leonard Katz, Yong Li, Simon J. Shaw	4
8	Coumarin-derived discodermolide analogues possessing equivalent antiproliferative activity to the natural product—a further simplification of the lactone region 2007 ·Organic & Biomolecular Chemistry ·Simon J. Shaw, Hugo G. Menzella, David C. Myles, Ming Xian, Amos B. Smith	10
9	Structure-based design of 7-carbamate analogs of geldanamycin 2005 ·Bioorganic & Medicinal Chemistry Letters ·Giulio Rastelli, Zong‐Qiang Tian, Zhan Wang, David C. Myles, Yaoquan Liu	35
10	15-Amido Erythromycins: Synthesis and in Vitro Activity of a New Class of Macrolide Antibiotics 2005 ·The Journal of Antibiotics ·Simon J. Shaw, Darren Abbanat, Gary W. Ashley, Karen Bush, Barbara D. Foleno, Mark J. Macielag, Dan Zhang, David C. Myles	14
11	Synthesis and in vitro antibiotic activity of 16-membered 9-O-arylalkyloxime macrolides 2005 ·Bioorganic & Medicinal Chemistry Letters ·Hong Fu, (unknown), Xiangrong Gu, Leonard Katz, David C. Myles	10
12	Synthesis and biological activities of novel 17-aminogeldanamycin derivatives 2004 ·Bioorganic & Medicinal Chemistry ·Zong‐Qiang Tian, Yaoquan Liu, Dan Zhang, Zhan Wang, Steven D. Dong, Christopher W. Carreras, Yiqing Zhou, Giulio Rastelli, Daniel V. Santi, David C. Myles	128
13	Design, synthesis and cytotoxicity of 7-deoxy aryl discodermolide analogues 2004 ·Bioorganic & Medicinal Chemistry Letters ·Mark A. Burlingame, Simon J. Shaw, Kurt F. Sundermann, Dan Zhang, (unknown), (unknown), Fenghua Liu, David C. Myles, Matthew J. LaMarche, Tomoyasu Hirose, B. Scott Freeze, Amos B. Smith	20
14	Isolation and Characterization of Novel Geldanamycin Analogues 2004 ·The Journal of Antibiotics ·Zhihao Hu, Yaoquan Liu, Zong‐Qiang Tian, Wei Ma, Courtney M. Starks, Rika Regentin, Peter Licari, David C. Myles, C. Richard Hutchinson	20
15	Rapid access to epothilone analogs via semisynthetic degradation and reconstruction of epothilone D 2004 ·Tetrahedron Letters ·Steven D. Dong, Kurt F. Sundermann, (unknown), (unknown), (unknown), David C. Myles	22
16	Novel biologically active natural and unnatural products 2003 ·Current Opinion in Biotechnology ·David C. Myles	29
17	Yeast and Rat Coq3 and Escherichia coli UbiG Polypeptides Catalyze Both O-Methyltransferase Steps in Coenzyme Q Biosynthesis 1999 ·Journal of Biological Chemistry ·Wayne W. Poon, Robert Barkovich, (unknown), Adam Frankel, Peter T. Lee, Jennifer N. Shepherd, David C. Myles, Catherine F. Clarke	97
18	Characterization of the COQ5 Gene from Saccharomyces cerevisiae EVIDENCE FOR A C-METHYLTRANSFERASE IN UBIQUINONE BIOSYNTHESIS 1997 ·Journal of Biological Chemistry ·Robert Barkovich, Andrey Shtanko, (unknown), Peter T. Lee, David C. Myles, Alexander Tzagoloff, Catherine F. Clarke	80
19	Adsorption of Sulfur Containing Molecules on Gold: The Effect of Oxidation on Monolayer Formation and Stability Characterized by Experiments and Theory 1995 ·Journal of the American Chemical Society ·Robin L. Garrell, (unknown), Daniel L. Severance, Nora A. McDonald, David C. Myles	111
20	Biotransformations in preparative organic chemistry, the use of isolated enzymes and whole cell systems in synthesis 1990 ·Bioorganic Chemistry ·David C. Myles, George M. Whitesides	49

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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