Darren J. Baker

25.3k total citations · 12 hit papers
81 papers, 17.9k citations indexed

About

Darren J. Baker is a scholar working on Molecular Biology, Physiology and Cell Biology. According to data from OpenAlex, Darren J. Baker has authored 81 papers receiving a total of 17.9k indexed citations (citations by other indexed papers that have themselves been cited), including 45 papers in Molecular Biology, 38 papers in Physiology and 20 papers in Cell Biology. Recurrent topics in Darren J. Baker's work include Telomeres, Telomerase, and Senescence (33 papers), Microtubule and mitosis dynamics (20 papers) and Neuroinflammation and Neurodegeneration Mechanisms (9 papers). Darren J. Baker is often cited by papers focused on Telomeres, Telomerase, and Senescence (33 papers), Microtubule and mitosis dynamics (20 papers) and Neuroinflammation and Neurodegeneration Mechanisms (9 papers). Darren J. Baker collaborates with scholars based in United States, Netherlands and Germany. Darren J. Baker's co-authors include Jan M. van Deursen, Bennett G. Childs, Matej Durik, Tobias Wijshake, James L. Kirkland, Karthik B. Jeganathan, Bart van de Sluis, Nathan K. LeBrasseur, Judith Campisi and Valery Krizhanovsky and has published in prestigious journals such as Nature, Science and Proceedings of the National Academy of Sciences.

In The Last Decade

Darren J. Baker

79 papers receiving 17.7k citations

Hit Papers

Clearance of p16Ink4a-positive senescent cells delays age... 2004 2026 2011 2018 2011 2016 2015 2020 2017 500 1000 1.5k 2.0k 2.5k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
    2011 2.7k citations Darren J. Baker, Tobias Wijshake et al. profile →
  2. Naturally occurring p16Ink4a-positive cells shorten healthy lifespan
    2016 2.0k citations Darren J. Baker, Bennett G. Childs et al. profile →
  3. Cellular senescence in aging and age-related disease: from mechanisms to therapy
    2015 1.7k citations Bennett G. Childs, Matej Durik et al. Nature Medicine profile →
  4. Cellular senescence in ageing: from mechanisms to therapeutic opportunities
    2020 1.4k citations Darren J. Baker et al. profile →
  5. Local clearance of senescent cells attenuates the development of post-traumatic osteoarthritis and creates a pro-regenerative environment
    2017 1.1k citations Darren J. Baker, Jan M. van Deursen et al. Nature Medicine profile →
  6. Clearance of senescent glial cells prevents tau-dependent pathology and cognitive decline
    2018 898 citations Jan M. van Deursen, Darren J. Baker et al. profile →
  7. Senescent cells: an emerging target for diseases of ageing
    2017 888 citations Bennett G. Childs, Darren J. Baker et al. profile →
  8. Senescent intimal foam cells are deleterious at all stages of atherosclerosis
    2016 857 citations Bennett G. Childs, Darren J. Baker et al. Science profile →
  9. Senescence and apoptosis: dueling or complementary cell fates?
    2014 650 citations Bennett G. Childs, Darren J. Baker et al. profile →
  10. BubR1 insufficiency causes early onset of aging-associated phenotypes and infertility in mice
    2004 586 citations Darren J. Baker, Karthik B. Jeganathan et al. profile →
  11. Cellular senescence in brain aging and neurodegenerative diseases: evidence and perspectives
    2018 360 citations Darren J. Baker, Ronald C. Petersen Journal of Clinical Investigation profile →
  12. Senescent alveolar macrophages promote early-stage lung tumorigenesis
    2023 109 citations Ines Sturmlechner, Cheng Zhang et al. profile →

Peers

Darren J. Baker
Marco Demaria Netherlands
Jan M. van Deursen United States
Fabrizio d’Adda di Fagagna Italy
João F. Passos United Kingdom
Jean‐Philippe Coppé United States
Laura J. Niedernhofer United States
Michael W. McBurney Canada
Raúl Mostoslavsky United States
John M. Sedivy United States
Pierre‐Yves Desprez United States
Marco Demaria Netherlands
Darren J. Baker
Citations per year, relative to Darren J. Baker Darren J. Baker (= 1×) peers Marco Demaria

Countries citing papers authored by Darren J. Baker

Since Specialization
Citations

This map shows the geographic impact of Darren J. Baker's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Darren J. Baker with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Darren J. Baker more than expected).

Fields of papers citing papers by Darren J. Baker

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Darren J. Baker. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Darren J. Baker. The network helps show where Darren J. Baker may publish in the future.

Co-authorship network of co-authors of Darren J. Baker

This figure shows the co-authorship network connecting the top 25 collaborators of Darren J. Baker. A scholar is included among the top collaborators of Darren J. Baker based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Darren J. Baker. Darren J. Baker is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Jachim, Sarah K., et al.. (2025). An Unbiased Cell‐Culture Selection Yields DNA Aptamers as Novel Senescent Cell‐Specific Reagents. Aging Cell. 24(11). e70245–e70245.
2.
Haas, Andrew R., S. Takafuji, Zheng Li, et al.. (2025). BubR1 Insufficiency Drives Transcriptomic Alterations and Pathology Associated With Cardiac Aging and Heart Failure. Aging Cell. 24(9). e70160–e70160.
3.
Bourdeau, Véronique, Sebastian Igelmann, Marlene Oeffinger, et al.. (2024). Senescent Macrophages Release Inflammatory Cytokines and RNA-Loaded Extracellular Vesicles to Circumvent Fibroblast Senescence. Biomedicines. 12(5). 1089–1089. 7 indexed citations
4.
Ree, Janine H. van, Karthik B. Jeganathan, Cheng Zhang, et al.. (2023). Hyperphosphorylated PTEN exerts oncogenic properties. Nature Communications. 14(1). 2983–2983. 5 indexed citations
5.
Sturmlechner, Ines, Karthik B. Jeganathan, Cheng Zhang, et al.. (2022). Senescent cells limit p53 activity via multiple mechanisms to remain viable. Nature Communications. 13(1). 3722–3722. 24 indexed citations
6.
Yu, Xiaoying, Erin E. Sundermann, Darren J. Baker, et al.. (2022). Current Challenges and Solutions for Clinical Management and Care of People with HIV: Findings from the 12th Annual International HIV and Aging Workshop. AIDS Research and Human Retroviruses. 39(1). 1–12. 3 indexed citations
7.
Childs, Bennett G., Cheng Zhang, Fahad Shuja, et al.. (2021). Senescent cells suppress innate smooth muscle cell repair functions in atherosclerosis. Nature Aging. 1(8). 698–714. 52 indexed citations
8.
Sturmlechner, Ines, Cheng Zhang, Karthik B. Jeganathan, et al.. (2021). p21 produces a bioactive secretome that places stressed cells under immunosurveillance. Science. 374(6567). eabb3420–eabb3420. 177 indexed citations
9.
Yao, Zhangting, Bhavna Murali, Qihao Ren, et al.. (2020). Therapy-Induced Senescence Drives Bone Loss. Cancer Research. 80(5). 1171–1182. 84 indexed citations
10.
Jeganathan, Karthik B., Jake A. Kloeber, Brian A. Davies, et al.. (2020). FoxM1 insufficiency hyperactivates Ect2–RhoA–mDia1 signaling to drive cancer. Nature Cancer. 1(10). 1010–1024. 4 indexed citations
11.
Baker, Darren J. & Ronald C. Petersen. (2018). Cellular senescence in brain aging and neurodegenerative diseases: evidence and perspectives. Journal of Clinical Investigation. 128(4). 1208–1216. 360 indexed citations breakdown →
12.
Wijshake, Tobias, Janine K. Kruit, Nicolette Huijkman, et al.. (2017). NF-κB p65 serine 467 phosphorylation sensitizes mice to weight gain and TNFα-or diet-induced inflammation. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1864(10). 1785–1798. 9 indexed citations
13.
Kanakkanthara, Arun, Karthik B. Jeganathan, Darren J. Baker, et al.. (2016). Cyclin A2 is an RNA binding protein that controls Mre11 mRNA translation. Science. 353(6307). 1549–1552. 59 indexed citations
14.
Childs, Bennett G., Darren J. Baker, Tobias Wijshake, et al.. (2016). Senescent intimal foam cells are deleterious at all stages of atherosclerosis. Science. 354(6311). 472–477. 857 indexed citations breakdown →
15.
Childs, Bennett G., Matej Durik, Darren J. Baker, & Jan M. van Deursen. (2015). Cellular senescence in aging and age-related disease: from mechanisms to therapy. Nature Medicine. 21(12). 1424–1435. 1670 indexed citations breakdown →
16.
Baker, Darren J. & Jan M. van Deursen. (2010). Chromosome missegregation causes colon cancer byAPCloss of heterozygosity. Cell Cycle. 9(9). 1711–1716. 28 indexed citations
17.
Jeganathan, Karthik B., Darren J. Baker, & Jan M. van Deursen. (2006). Securin Associates with APCCdh1 in Prometaphase but its Destruction is Delayed by Rae1 and Nup98 until the Metaphase/Anaphase Transition. Cell Cycle. 5(4). 366–370. 52 indexed citations
18.
Niessen, Petra, Sander S. Rensen, Jan van Deursen, et al.. (2005). Smoothelin-A Is Essential for Functional Intestinal Smooth Muscle Contractility in Mice. Gastroenterology. 129(5). 1592–1601. 62 indexed citations
19.
Baker, Darren J., et al.. (2005). The mitotic checkpoint in cancer and aging: what have mice taught us?. Current Opinion in Cell Biology. 17(6). 583–589. 73 indexed citations
20.
Babu, Jeganathan Ramesh, Karthik B. Jeganathan, Darren J. Baker, et al.. (2003). Rae1 is an essential mitotic checkpoint regulator that cooperates with Bub3 to prevent chromosome missegregation. The Journal of Cell Biology. 160(3). 341–353. 294 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact

Breakdown of academic impact, for papers by Marco Demaria Breakdown of academic impact, for papers by Jan M. van Deursen Breakdown of academic impact, for papers by Fabrizio d’Adda di Fagagna Breakdown of academic impact, for papers by João F. Passos Breakdown of academic impact, for papers by Jean‐Philippe Coppé Breakdown of academic impact, for papers by Laura J. Niedernhofer Breakdown of academic impact, for papers by Michael W. McBurney Breakdown of academic impact, for papers by Raúl Mostoslavsky Breakdown of academic impact, for papers by John M. Sedivy Breakdown of academic impact, for papers by Pierre‐Yves Desprez
Rankless by CCL
2026