Daisuke Aki

3.4k total citations · 3 hit papers
27 papers, 2.7k citations indexed

About

Daisuke Aki is a scholar working on Immunology, Molecular Biology and Oncology. According to data from OpenAlex, Daisuke Aki has authored 27 papers receiving a total of 2.7k indexed citations (citations by other indexed papers that have themselves been cited), including 22 papers in Immunology, 11 papers in Molecular Biology and 11 papers in Oncology. Recurrent topics in Daisuke Aki's work include Cytokine Signaling Pathways and Interactions (8 papers), Immune Response and Inflammation (8 papers) and Immune Cell Function and Interaction (6 papers). Daisuke Aki is often cited by papers focused on Cytokine Signaling Pathways and Interactions (8 papers), Immune Response and Inflammation (8 papers) and Immune Cell Function and Interaction (6 papers). Daisuke Aki collaborates with scholars based in Japan, United States and China. Daisuke Aki's co-authors include Toshikatsu Hanada, Hiroyuki Mori, Akihiko Yoshimura, Masanobu Ohishi, Hideo Yasukawa, Ryuichi Mashima, Ichiko Kinjyo, Kyoko Inagaki‐Ohara, Masato Kubo and Hiroki Yoshida and has published in prestigious journals such as Journal of Biological Chemistry, Journal of Clinical Investigation and Nature Medicine.

In The Last Decade

Daisuke Aki

27 papers receiving 2.7k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

IL-6 induces an anti-inflammatory response in the absence of SOCS3 in macrophages

2003 647 citations Hideo Yasukawa, Masanobu Ohishi et al. Nature Immunology profile →
SOCS1/JAB Is a Negative Regulator of LPS-Induced Macrophage Activation

2002 540 citations Ichiko Kinjyo, Toshikatsu Hanada et al. Immunity profile →
Socs3 deficiency in the brain elevates leptin sensitivity and confers resistance to diet-induced obesity

2004 517 citations Hiroyuki Mori, Toshikatsu Hanada et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Daisuke Aki Japan	20	1.3k	918	851	394	386	27	2.7k
Chen Varol Israel	24	3.4k 2.6×	657 0.7×	1.3k 1.5×	592 1.5×	236 0.6×	48	5.5k
Anne F. McGettrick Ireland	22	1.5k 1.1×	254 0.3×	1.1k 1.3×	348 0.9×	557 1.4×	27	2.8k
Dietrich B. Conze United States	21	1.5k 1.2×	726 0.8×	1.6k 1.8×	384 1.0×	965 2.5×	29	3.2k
Pascale Chomarat France	27	2.9k 2.2×	1.1k 1.2×	1.0k 1.2×	388 1.0×	231 0.6×	32	4.8k
Nobuhiro Nakano Japan	26	1.4k 1.1×	496 0.5×	794 0.9×	142 0.4×	218 0.6×	79	3.1k
Ulla M. Sarmiento United States	19	1.5k 1.1×	502 0.5×	696 0.8×	302 0.8×	201 0.5×	27	2.5k
Kyoji Hioki Japan	19	874 0.7×	690 0.8×	830 1.0×	187 0.5×	210 0.5×	63	2.6k
Brendan Hilliard United States	31	2.8k 2.2×	695 0.8×	1.4k 1.6×	304 0.8×	777 2.0×	68	4.4k
Rainer Glauben Germany	26	965 0.7×	337 0.4×	1.1k 1.2×	349 0.9×	371 1.0×	55	2.4k
Cristiano Rumio Italy	29	797 0.6×	577 0.6×	1.2k 1.4×	201 0.5×	272 0.7×	80	2.8k

Countries citing papers authored by Daisuke Aki

Since Specialization

Citations

This map shows the geographic impact of Daisuke Aki's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Daisuke Aki with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Daisuke Aki more than expected).

Fields of papers citing papers by Daisuke Aki

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Daisuke Aki. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Daisuke Aki. The network helps show where Daisuke Aki may publish in the future.

Co-authorship network of co-authors of Daisuke Aki

This figure shows the co-authorship network connecting the top 25 collaborators of Daisuke Aki. A scholar is included among the top collaborators of Daisuke Aki based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Daisuke Aki. Daisuke Aki is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Aki, Daisuke, Tanakorn Srirat, Shigeyuki Shichino, et al.. (2024). The Nr4a family regulates intrahepatic Treg proliferation and liver fibrosis in MASLD models. Journal of Clinical Investigation. 134(23). 6 indexed citations

Yoshimura, Akihiko, Daisuke Aki, & Minako Ito. (2021). SOCS, SPRED, and NR4a: Negative regulators of cytokine signaling and transcription in immune tolerance. Proceedings of the Japan Academy Series B. 97(6). 277–291. 14 indexed citations

Zhu, Yangyang, et al.. (2019). The E3 ligase VHL promotes follicular helper T cell differentiation via glycolytic-epigenetic control. The Journal of Experimental Medicine. 216(7). 1664–1681. 80 indexed citations

Aki, Daisuke, Hui Li, Wen Zhang, et al.. (2018). The E3 ligases Itch and WWP2 cooperate to limit TH2 differentiation by enhancing signaling through the TCR. Nature Immunology. 19(7). 766–775. 31 indexed citations

Aki, Daisuke, et al.. (2018). Immune regulation by protein ubiquitination: roles of the E3 ligases VHL and Itch. Protein & Cell. 10(6). 395–404. 18 indexed citations

Park, Yoon, et al.. (2014). The Ubiquitin System in Immune Regulation. Advances in immunology. 124. 17–66. 58 indexed citations

Nagamachi, Akiko, Hirotaka Matsui, Hiroya Asou, et al.. (2013). Haploinsufficiency of SAMD9L, an Endosome Fusion Facilitator, Causes Myeloid Malignancies in Mice Mimicking Human Diseases with Monosomy 7. Cancer Cell. 24(3). 305–317. 103 indexed citations

Matsui, Hirotaka, Hiroya Asou, Akiko Nagamachi, et al.. (2012). Poly-ADP Ribosylation of Miki by tankyrase-1 Promotes Centrosome Maturation. Molecular Cell. 47(5). 694–706. 51 indexed citations

Aki, Daisuke & Yun‐Cai Liu. (2011). To go or not to go: the “Itchy” effect on the destiny of hematopoietic stem cells. Cell Research. 21(8). 1161–1163. 1 indexed citations

10.

Matsui, Hirotaka, et al.. (2010). The Dynactin Complex Maintains the Integrity of Metaphasic Centrosomes to Ensure Transition to Anaphase. Journal of Biological Chemistry. 286(7). 5589–5598. 8 indexed citations

11.

Saeki, Kazuko, Satoru Fukuyama, Toranoshin Ayada, et al.. (2009). A Major Lipid Raft Protein Raftlin Modulates T Cell Receptor Signaling and Enhances Th17-Mediated Autoimmune Responses. The Journal of Immunology. 182(10). 5929–5937. 53 indexed citations

12.

Kurosawa, Hidemitsu, Jiro Kikuchi, Yusuke Furukawa, et al.. (2009). Up-regulation of Survivin by the E2A-HLF Chimera Is Indispensable for the Survival of t(17;19)-positive Leukemia Cells. Journal of Biological Chemistry. 285(3). 1850–1860. 11 indexed citations

13.

Asou, Hiroya, Hirotaka Matsui, Akiko Nagamachi, et al.. (2009). Identification of a common microdeletion cluster in 7q21.3 subband among patients with myeloid leukemia and myelodysplastic syndrome. Biochemical and Biophysical Research Communications. 383(2). 245–251. 55 indexed citations

14.

Aki, Daisuke, Yasumasa Minoda, Hideyuki Yoshida, et al.. (2008). Peptidoglycan and lipopolysaccharide activate PLCγ2, leading to enhanced cytokine production in macrophages and dendritic cells. Genes to Cells. 13(2). 199–208. 60 indexed citations

15.

Minoda, Yasumasa, Kazuko Saeki, Daisuke Aki, et al.. (2006). A novel Zinc finger protein, ZCCHC11, interacts with TIFA and modulates TLR signaling. Biochemical and Biophysical Research Communications. 344(3). 1023–1030. 41 indexed citations

16.

Ohishi, Masanobu, Yumiko Matsumura, Daisuke Aki, et al.. (2005). Suppressors of Cytokine Signaling-1 and -3 Regulate Osteoclastogenesis in the Presence of Inflammatory Cytokines. The Journal of Immunology. 174(5). 3024–3031. 36 indexed citations

17.

Mashima, Ryuichi, Kazuko Saeki, Daisuke Aki, et al.. (2005). FLN29, a Novel Interferon- and LPS-inducible Gene Acting as a Negative Regulator of Toll-like Receptor Signaling. Journal of Biological Chemistry. 280(50). 41289–41297. 53 indexed citations

18.

Yasukawa, Hideo, Masanobu Ohishi, Hiroyuki Mori, et al.. (2003). IL-6 induces an anti-inflammatory response in the absence of SOCS3 in macrophages. Nature Immunology. 4(6). 551–556. 647 indexed citations breakdown →

19.

Yoshimura, Akihiko, Hiroyuki Mori, Masanobu Ohishi, Daisuke Aki, & Toshikatsu Hanada. (2003). Negative regulation of cytokine signaling influences inflammation. Current Opinion in Immunology. 15(6). 704–708. 105 indexed citations

20.

Kinjyo, Ichiko, Toshikatsu Hanada, Kyoko Inagaki‐Ohara, et al.. (2002). SOCS1/JAB Is a Negative Regulator of LPS-Induced Macrophage Activation. Immunity. 17(5). 583–591. 540 indexed citations breakdown →

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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