Keiyo Takubo

12.9k total citations · 7 hit papers
106 papers, 9.3k citations indexed

About

Keiyo Takubo is a scholar working on Molecular Biology, Hematology and Cancer Research. According to data from OpenAlex, Keiyo Takubo has authored 106 papers receiving a total of 9.3k indexed citations (citations by other indexed papers that have themselves been cited), including 53 papers in Molecular Biology, 52 papers in Hematology and 22 papers in Cancer Research. Recurrent topics in Keiyo Takubo's work include Hematopoietic Stem Cell Transplantation (40 papers), Acute Myeloid Leukemia Research (19 papers) and Cancer, Hypoxia, and Metabolism (15 papers). Keiyo Takubo is often cited by papers focused on Hematopoietic Stem Cell Transplantation (40 papers), Acute Myeloid Leukemia Research (19 papers) and Cancer, Hypoxia, and Metabolism (15 papers). Keiyo Takubo collaborates with scholars based in Japan, United States and Singapore. Keiyo Takubo's co-authors include Toshio Suda, Atsushi Hirao, Fumio Arai, Sahoko Matsuoka, Keisuke Ito, Masako Ohmura, Kentaro Hosokawa, Gregg L. Semenza, Yasuo Ikeda and Hidetaka Sato and has published in prestigious journals such as Nature, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Keiyo Takubo

105 papers receiving 9.2k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Tie2/Angiopoietin-1 Signaling Regulates Hematopoietic Stem Cell Quiescence in the Bone Marrow Niche

2004 1.5k citations Fumio Arai, Atsushi Hirao et al. profile →
Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells

2006 1.1k citations Keisuke Ito, Atsushi Hirao et al. Nature Medicine profile →
Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells

2004 930 citations Keisuke Ito, Atsushi Hirao et al. Nature profile →
Regulation of the HIF-1α Level Is Essential for Hematopoietic Stem Cells

2010 676 citations Keiyo Takubo, Nobuhito Goda et al. Cell stem cell profile →
Metabolic Regulation of Hematopoietic Stem Cells in the Hypoxic Niche

2011 617 citations Toshio Suda, Keiyo Takubo et al. Cell stem cell profile →
Regulation of Glycolysis by Pdk Functions as a Metabolic Checkpoint for Cell Cycle Quiescence in Hematopoietic Stem Cells

2013 586 citations Keiyo Takubo, Go Nagamatsu et al. Cell stem cell profile →
Thrombopoietin/MPL Signaling Regulates Hematopoietic Stem Cell Quiescence and Interaction with the Osteoblastic Niche

2007 568 citations Hiroki Yoshihara, Fumio Arai et al. Cell stem cell profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Keiyo Takubo Japan	39	4.4k	3.6k	2.1k	1.6k	1.5k	106	9.3k
Fumio Arai Japan	37	4.6k 1.1×	3.6k 1.0×	2.2k 1.1×	1.8k 1.1×	1.2k 0.8×	98	9.2k
Claus Nerlov United Kingdom	49	5.1k 1.2×	2.9k 0.8×	2.7k 1.3×	892 0.5×	1.1k 0.7×	105	8.8k
Sérgio Dias Portugal	37	5.9k 1.3×	2.0k 0.5×	1.4k 0.7×	1.4k 0.9×	2.4k 1.6×	86	9.7k
Emmanuelle Passegué United States	54	7.8k 1.8×	5.5k 1.5×	4.4k 2.1×	2.1k 1.3×	2.1k 1.4×	98	15.3k
Richard Moriggl Austria	57	3.9k 0.9×	1.6k 0.4×	3.5k 1.6×	1.3k 0.8×	1.4k 0.9×	176	10.2k
Donald C. Foster United States	43	2.2k 0.5×	3.8k 1.0×	1.4k 0.7×	1.3k 0.8×	923 0.6×	77	8.2k
Carl R. Walkley Australia	40	5.0k 1.1×	1.5k 0.4×	1.7k 0.8×	748 0.5×	946 0.6×	110	7.3k
Sahoko Matsuoka Japan	18	2.5k 0.6×	2.6k 0.7×	1.4k 0.7×	1.2k 0.7×	559 0.4×	29	5.4k
Giao Hangoc United States	46	3.0k 0.7×	3.4k 0.9×	3.0k 1.4×	1.4k 0.9×	539 0.3×	115	8.6k
Isabelle Petit France	37	2.8k 0.6×	3.3k 0.9×	3.0k 1.4×	1.6k 1.0×	653 0.4×	65	8.7k

Countries citing papers authored by Keiyo Takubo

Since Specialization

Citations

This map shows the geographic impact of Keiyo Takubo's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Keiyo Takubo with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Keiyo Takubo more than expected).

Fields of papers citing papers by Keiyo Takubo

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Keiyo Takubo. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Keiyo Takubo. The network helps show where Keiyo Takubo may publish in the future.

Co-authorship network of co-authors of Keiyo Takubo

This figure shows the co-authorship network connecting the top 25 collaborators of Keiyo Takubo. A scholar is included among the top collaborators of Keiyo Takubo based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Keiyo Takubo. Keiyo Takubo is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Yahagi, Ayano, et al.. (2024). Abcb10 regulates murine hematopoietic stem cell potential and erythroid differentiation. Experimental Hematology. 135. 104191–104191.

Ito, Kei, Satoshi Suzuki, Hiroki Takeda, et al.. (2023). Potential Involvement of Oxidative Stress in Ligamentum Flavum Hypertrophy. Journal of Clinical Medicine. 12(3). 808–808. 4 indexed citations

Kobayashi, Hiroshi, S. Watanuki, Daiki Karigane, et al.. (2023). Distinct roles of the preparatory and payoff phases of glycolysis in hematopoietic stem cells. Experimental Hematology. 124. 56–67. 4 indexed citations

Morikawa, Takayuki, et al.. (2022). Quantitative Analysis of Sympathetic and Nociceptive Innervation Across Bone Marrow Regions in Mice. Experimental Hematology. 112-113. 44–59.e6. 10 indexed citations

Kobayashi, Hiroshi & Keiyo Takubo. (2021). A Culture Method to Maintain Quiescent Human Hematopoietic Stem Cells. Journal of Visualized Experiments. 1 indexed citations

Karigane, Daiki, Hiroshi Kobayashi, Takayuki Morikawa, et al.. (2021). p38α plays differential roles in hematopoietic stem cell activity dependent on aging contexts. Journal of Biological Chemistry. 296. 100563–100563. 7 indexed citations

Shibata, Eri, Midori Shimada, Hiroaki Kanda, et al.. (2021). Characterization of genetically modified mice for phosphoglycerate mutase, a vitally-essential enzyme in glycolysis. PLoS ONE. 16(4). e0250856–e0250856. 10 indexed citations

Tsugawa, Hitoshi, Yasuaki Kabe, Yuki Sugiura, et al.. (2020). Short-chain fatty acids bind to apoptosis-associated speck-like protein to activate inflammasome complex to prevent Salmonella infection. PLoS Biology. 18(9). e3000813–e3000813. 38 indexed citations

Suzuki, Satoshi, Takeshi Fujii, Takayuki Morikawa, et al.. (2019). Potential involvement of semaphorin 3A in maintaining intervertebral disc tissue homeostasis. Journal of Orthopaedic Research®. 37(4). 972–980. 11 indexed citations

10.

Karigane, Daiki, Hidenori Kasahara, Masatoshi Sakurai, et al.. (2016). Correlation of Expression of CD25 in Hematopoietic Stem/Progenitor Cell Fraction of Bone Marrow Cells with Response to Tyrosine Kinase Inhibitors in Chronic Myelogenous Leukemia Patients. Blood. 128(22). 3061–3061. 1 indexed citations

11.

Koide, Shuhei, Keiyo Takubo, Motohiko Oshima, et al.. (2015). Histone methyltransferase Setdb1 regulates energy metabolism in hematopoietic stem and progenitor cells. Experimental Hematology. 43(9). S73–S73. 3 indexed citations

12.

Nakamura‐Ishizu, Ayako, Keiyo Takubo, Hiroshi Kobayashi, Katsue Suzuki‐Inoue, & Toshio Suda. (2015). CLEC-2 in megakaryocytes is critical for maintenance of hematopoietic stem cells in the bone marrow. The Journal of Experimental Medicine. 212(12). 2133–2146. 96 indexed citations

13.

Nagamatsu, Go, et al.. (2014). Telomerase Reverse Transcriptase Has an Extratelomeric Function in Somatic Cell Reprogramming. Journal of Biological Chemistry. 289(22). 15776–15787. 14 indexed citations

14.

Takaesu, Giichi, Maiko Inagaki, Keiyo Takubo, et al.. (2012). TAK1 (MAP3K7) Signaling Regulates Hematopoietic Stem Cells through TNF-Dependent and -Independent Mechanisms. PLoS ONE. 7(11). e51073–e51073. 11 indexed citations

15.

Hosokawa, Kentaro, Fumio Arai, Hiroki Yoshihara, et al.. (2010). Cadherin-Based Adhesion Is a Potential Target for Niche Manipulation to Protect Hematopoietic Stem Cells in Adult Bone Marrow. Cell stem cell. 6(3). 194–198. 77 indexed citations

16.

Kubota, Yoshiaki, Keiyo Takubo, Takatsune Shimizu, et al.. (2009). M-CSF inhibition selectively targets pathological angiogenesis and lymphangiogenesis. The Journal of Experimental Medicine. 206(5). 1089–1102. 317 indexed citations

17.

Shima, Haruko, Keiyo Takubo, Hiroko Iwasaki, et al.. (2008). Reconstitution activity of hypoxic cultured human cord blood CD34-positive cells in NOG mice. Biochemical and Biophysical Research Communications. 378(3). 467–472. 39 indexed citations

18.

Ito, Keisuke, Keiyo Takubo, Fumio Arai, et al.. (2007). Regulation of Reactive Oxygen Species by Atm Is Essential for Proper Response to DNA Double-Strand Breaks in Lymphocytes. The Journal of Immunology. 178(1). 103–110. 91 indexed citations

19.

Ito, Keisuke, Atsushi Hirao, Fumio Arai, et al.. (2006). Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells. Nature Medicine. 12(4). 446–451. 1075 indexed citations breakdown →

20.

Ito, Keisuke, Atsushi Hirao, Fumio Arai, et al.. (2004). Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells. Nature. 431(7011). 997–1002. 930 indexed citations breakdown →

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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